Table of Content
I.Project Summary
II.Workflow Checklist
III.NGS Sequencing Results
IV.Complete Report Download
V.Raw Sequence Data Download
VI.Analysis - DADA2 Read Processing
 Sample Meta Info
 Read Count by Sample
VII.Analysis - Read Taxonomy Assignment
 Taxonomy Barplots
VIII.Analysis - Alpha Diversity
IX.Analysis - Beta Diversity
X.Analysis - Differential Abundance
 ANCOM Result
 LEfSe Result
XI.Analysis - Heatmap Profile
XII.Analysis - Network Association
XIII.Disclaimer

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FOMC Service Report

16S rRNA Gene V1V3 Amplicon Sequencing

Version V1.50

Version History

The Forsyth Institute, Cambridge, MA, USA
June 03, 2025

Project ID: FOMC19514_Kenvue

I. Project Summary

Project FOMC19514_Kenvue services include NGS sequencing of the V1V3 region of the 16S rRNA gene amplicons from the samples. First and foremost, please download this report, as well as the sequence raw data from the download links provided below. These links will expire after 60 days. We cannot guarantee the availability of your data after 60 days.

Full Bioinformatics analysis service was requested. We provide many analyses, starting from the raw sequence quality and noise filtering, pair reads merging, as well as chimera filtering for the sequences, using the DADA2 denosing algorithm and pipeline.

We also provide many downstream analyses such as taxonomy assignment, alpha and beta diversity analyses, and differential abundance analysis.

For taxonomy assignment, most informative would be the taxonomy barplots. We provide an interactive barplots to show the relative abundance of microbes at different taxonomy levels (from Phylum to species) that you can choose.

If you specify which groups of samples you want to compare for differential abundance, we provide both ANCOM and LEfSe differential abundance analysis.

 

II. Workflow Checklist

☑1.Sample Received
☑2.Sample Quality Evaluated
☑3.Sample Prepared for Sequencing
☑4.Next-Gen Sequencing
☑5.Sequence Quality Check
☑6.Absolute Abundance
☑7.Report and Raw Sequence Data Available for Download
☑8.Bioinformatics Analysis - Reads Processing (DADA2 Quality Trimming, Denoising, Paired Reads Merging)
☑9.Bioinformatics Analysis - Reads Taxonomy Assignment
☑10.Bioinformatics Analysis - Alpha Diversity Analysis
☑11.Bioinformatics Analysis - Beta Diversity Analysis
☑12.Bioinformatics Analysis - Differential Abundance Analysis
☑13.Bioinformatics Analysis - Heatmap Profile
☑14.Bioinformatics Analysis - Network Association
 

III. NGS Sequencing

The samples were processed and analyzed with the ZymoBIOMICS® Service: Targeted Metagenomic Sequencing (Zymo Research, Irvine, CA).

DNA Extraction: If DNA extraction was performed, the following DNA extraction kit was used according to the manufacturer’s instructions:

☑ZymoBIOMICS®-96 MagBead DNA Kit (Zymo Research, Irvine, CA)
☐N/A (DNA Extraction Not Performed)
Elution Volume: 50µL
Additional Notes: NA

Targeted Library Preparation: The DNA samples were prepared for targeted sequencing with the Quick-16S™ NGS Library Prep Kit (Zymo Research, Irvine, CA). These primers were custom designed by Zymo Research to provide the best coverage of the 16S gene while maintaining high sensitivity. The primer sets used in this project are marked below:

☐Quick-16S™ Primer Set V1-V2 (Zymo Research, Irvine, CA)
☑Quick-16S™ Primer Set V1-V3 (Zymo Research, Irvine, CA)
☐Quick-16S™ Primer Set V3-V4 (Zymo Research, Irvine, CA)
☐Quick-16S™ Primer Set V4 (Zymo Research, Irvine, CA)
☐Quick-16S™ Primer Set V6-V8 (Zymo Research, Irvine, CA)
Additional Notes: NA

The sequencing library was prepared using an innovative library preparation process in which PCR reactions were performed in real-time PCR machines to control cycles and therefore limit PCR chimera formation. The final PCR products were quantified with qPCR fluorescence readings and pooled together based on equal molarity. The final pooled library was cleaned up with the Select-a-Size DNA Clean & Concentrator™ (Zymo Research, Irvine, CA), then quantified with TapeStation® (Agilent Technologies, Santa Clara, CA) and Qubit® (Thermo Fisher Scientific, Waltham, WA).

Control Samples: The ZymoBIOMICS® Microbial Community Standard (Zymo Research, Irvine, CA) was used as a positive control for each DNA extraction, if performed. The ZymoBIOMICS® Microbial Community DNA Standard (Zymo Research, Irvine, CA) was used as a positive control for each targeted library preparation. Negative controls (i.e. blank extraction control, blank library preparation control) were included to assess the level of bioburden carried by the wet-lab process.

Sequencing: The final library was sequenced on Illumina® NextSeq 2000™ with a p1 (Illumina, Sand Diego, CA) reagent kit (600 cycles). The sequencing was performed with 25% PhiX spike-in.

Absolute Abundance Quantification*: A quantitative real-time PCR was set up with a standard curve. The standard curve was made with plasmid DNA containing one copy of the 16S gene and one copy of the fungal ITS2 region prepared in 10-fold serial dilutions. The primers used were the same as those used in Targeted Library Preparation. The equation generated by the plasmid DNA standard curve was used to calculate the number of gene copies in the reaction for each sample. The PCR input volume (2 µl) was used to calculate the number of gene copies per microliter in each DNA sample.
The number of genome copies per microliter DNA sample was calculated by dividing the gene copy number by an assumed number of gene copies per genome. The value used for 16S copies per genome is 4. The value used for ITS copies per genome is 200. The amount of DNA per microliter DNA sample was calculated using an assumed genome size of 4.64 x 106 bp, the genome size of Escherichia coli, for 16S samples, or an assumed genome size of 1.20 x 107 bp, the genome size of Saccharomyces cerevisiae, for ITS samples. This calculation is shown below:

Calculated Total DNA = Calculated Total Genome Copies × Assumed Genome Size (4.64 × 106 bp) ×
Average Molecular Weight of a DNA bp (660 g/mole/bp) ÷ Avogadro’s Number (6.022 x 1023/mole)


* Absolute Abundance Quantification is only available for 16S and ITS analyses.

The absolute abundance standard curve data can be viewed in Excel here:

The absolute abundance standard curve is shown below:

Absolute Abundance Standard Curve

 

IV. Complete Report Download

The complete report of your project, including all links in this report, can be downloaded by clicking the link provided below. The downloaded file is a compressed ZIP file and once unzipped, open the file “REPORT.html” (may only shown as "REPORT" in your computer) by double clicking it. Your default web browser will open it and you will see the exact content of this report.

Please download and save the file to your computer storage device. The download link will expire after 60 days upon your receiving of this report.

Complete report download link:

To view the report, please follow the following steps:

1.Download the .zip file from the report link above.
2.Extract all the contents of the downloaded .zip file to your desktop.
3.Open the extracted folder and find the "REPORT.html" (may shown as only "REPORT").
4.Open (double-clicking) the REPORT.html file. Your default browser will open the top age of the complete report. Within the report, there are links to view all the analyses performed for the project.

 

V. Raw Sequence Data Download

The raw NGS sequence data is available for download with the link provided below. The data is a compressed ZIP file and can be unzipped to individual sequence files. Since this is a pair-end sequencing, each of your samples is represented by two sequence files, one for READ 1, with the file extension “*_R1.fastq.gz”, another READ 2, with the file extension “*_R1.fastq.gz”. The files are in FASTQ format and are compressed. FASTQ format is a text-based data format for storing both a biological sequence and its corresponding quality scores. Most sequence analysis software will be able to open them. The Sample IDs associated with the R1 and R2 fastq files are listed in the table below:



Sample IDOriginal Sample IDRead 1 File NameRead 2 File Name


F19514.S100original sample ID herezr19514_100V1V3_R1.fastq.gzzr19514_100V1V3_R2.fastq.gz


F19514.S101original sample ID herezr19514_101V1V3_R1.fastq.gzzr19514_101V1V3_R2.fastq.gz


F19514.S102original sample ID herezr19514_102V1V3_R1.fastq.gzzr19514_102V1V3_R2.fastq.gz


F19514.S103original sample ID herezr19514_103V1V3_R1.fastq.gzzr19514_103V1V3_R2.fastq.gz


F19514.S104original sample ID herezr19514_104V1V3_R1.fastq.gzzr19514_104V1V3_R2.fastq.gz


F19514.S105original sample ID herezr19514_105V1V3_R1.fastq.gzzr19514_105V1V3_R2.fastq.gz


F19514.S106original sample ID herezr19514_106V1V3_R1.fastq.gzzr19514_106V1V3_R2.fastq.gz


F19514.S107original sample ID herezr19514_107V1V3_R1.fastq.gzzr19514_107V1V3_R2.fastq.gz


F19514.S108original sample ID herezr19514_108V1V3_R1.fastq.gzzr19514_108V1V3_R2.fastq.gz


F19514.S109original sample ID herezr19514_109V1V3_R1.fastq.gzzr19514_109V1V3_R2.fastq.gz


F19514.S010original sample ID herezr19514_10V1V3_R1.fastq.gzzr19514_10V1V3_R2.fastq.gz


F19514.S110original sample ID herezr19514_110V1V3_R1.fastq.gzzr19514_110V1V3_R2.fastq.gz


F19514.S111original sample ID herezr19514_111V1V3_R1.fastq.gzzr19514_111V1V3_R2.fastq.gz


F19514.S112original sample ID herezr19514_112V1V3_R1.fastq.gzzr19514_112V1V3_R2.fastq.gz


F19514.S113original sample ID herezr19514_113V1V3_R1.fastq.gzzr19514_113V1V3_R2.fastq.gz


F19514.S114original sample ID herezr19514_114V1V3_R1.fastq.gzzr19514_114V1V3_R2.fastq.gz


F19514.S115original sample ID herezr19514_115V1V3_R1.fastq.gzzr19514_115V1V3_R2.fastq.gz


F19514.S116original sample ID herezr19514_116V1V3_R1.fastq.gzzr19514_116V1V3_R2.fastq.gz


F19514.S117original sample ID herezr19514_117V1V3_R1.fastq.gzzr19514_117V1V3_R2.fastq.gz


F19514.S118original sample ID herezr19514_118V1V3_R1.fastq.gzzr19514_118V1V3_R2.fastq.gz


F19514.S119original sample ID herezr19514_119V1V3_R1.fastq.gzzr19514_119V1V3_R2.fastq.gz


F19514.S011original sample ID herezr19514_11V1V3_R1.fastq.gzzr19514_11V1V3_R2.fastq.gz


F19514.S120original sample ID herezr19514_120V1V3_R1.fastq.gzzr19514_120V1V3_R2.fastq.gz


F19514.S121original sample ID herezr19514_121V1V3_R1.fastq.gzzr19514_121V1V3_R2.fastq.gz


F19514.S122original sample ID herezr19514_122V1V3_R1.fastq.gzzr19514_122V1V3_R2.fastq.gz


F19514.S123original sample ID herezr19514_123V1V3_R1.fastq.gzzr19514_123V1V3_R2.fastq.gz


F19514.S124original sample ID herezr19514_124V1V3_R1.fastq.gzzr19514_124V1V3_R2.fastq.gz


F19514.S125original sample ID herezr19514_125V1V3_R1.fastq.gzzr19514_125V1V3_R2.fastq.gz


F19514.S126original sample ID herezr19514_126V1V3_R1.fastq.gzzr19514_126V1V3_R2.fastq.gz


F19514.S127original sample ID herezr19514_127V1V3_R1.fastq.gzzr19514_127V1V3_R2.fastq.gz


F19514.S128original sample ID herezr19514_128V1V3_R1.fastq.gzzr19514_128V1V3_R2.fastq.gz


F19514.S129original sample ID herezr19514_129V1V3_R1.fastq.gzzr19514_129V1V3_R2.fastq.gz


F19514.S012original sample ID herezr19514_12V1V3_R1.fastq.gzzr19514_12V1V3_R2.fastq.gz


F19514.S130original sample ID herezr19514_130V1V3_R1.fastq.gzzr19514_130V1V3_R2.fastq.gz


F19514.S131original sample ID herezr19514_131V1V3_R1.fastq.gzzr19514_131V1V3_R2.fastq.gz


F19514.S132original sample ID herezr19514_132V1V3_R1.fastq.gzzr19514_132V1V3_R2.fastq.gz


F19514.S133original sample ID herezr19514_133V1V3_R1.fastq.gzzr19514_133V1V3_R2.fastq.gz


F19514.S134original sample ID herezr19514_134V1V3_R1.fastq.gzzr19514_134V1V3_R2.fastq.gz


F19514.S135original sample ID herezr19514_135V1V3_R1.fastq.gzzr19514_135V1V3_R2.fastq.gz


F19514.S136original sample ID herezr19514_136V1V3_R1.fastq.gzzr19514_136V1V3_R2.fastq.gz


F19514.S137original sample ID herezr19514_137V1V3_R1.fastq.gzzr19514_137V1V3_R2.fastq.gz


F19514.S138original sample ID herezr19514_138V1V3_R1.fastq.gzzr19514_138V1V3_R2.fastq.gz


F19514.S139original sample ID herezr19514_139V1V3_R1.fastq.gzzr19514_139V1V3_R2.fastq.gz


F19514.S013original sample ID herezr19514_13V1V3_R1.fastq.gzzr19514_13V1V3_R2.fastq.gz


F19514.S140original sample ID herezr19514_140V1V3_R1.fastq.gzzr19514_140V1V3_R2.fastq.gz


F19514.S141original sample ID herezr19514_141V1V3_R1.fastq.gzzr19514_141V1V3_R2.fastq.gz


F19514.S142original sample ID herezr19514_142V1V3_R1.fastq.gzzr19514_142V1V3_R2.fastq.gz


F19514.S143original sample ID herezr19514_143V1V3_R1.fastq.gzzr19514_143V1V3_R2.fastq.gz


F19514.S144original sample ID herezr19514_144V1V3_R1.fastq.gzzr19514_144V1V3_R2.fastq.gz


F19514.S145original sample ID herezr19514_145V1V3_R1.fastq.gzzr19514_145V1V3_R2.fastq.gz


F19514.S146original sample ID herezr19514_146V1V3_R1.fastq.gzzr19514_146V1V3_R2.fastq.gz


F19514.S147original sample ID herezr19514_147V1V3_R1.fastq.gzzr19514_147V1V3_R2.fastq.gz


F19514.S148original sample ID herezr19514_148V1V3_R1.fastq.gzzr19514_148V1V3_R2.fastq.gz


F19514.S149original sample ID herezr19514_149V1V3_R1.fastq.gzzr19514_149V1V3_R2.fastq.gz


F19514.S014original sample ID herezr19514_14V1V3_R1.fastq.gzzr19514_14V1V3_R2.fastq.gz


F19514.S150original sample ID herezr19514_150V1V3_R1.fastq.gzzr19514_150V1V3_R2.fastq.gz


F19514.S151original sample ID herezr19514_151V1V3_R1.fastq.gzzr19514_151V1V3_R2.fastq.gz


F19514.S152original sample ID herezr19514_152V1V3_R1.fastq.gzzr19514_152V1V3_R2.fastq.gz


F19514.S153original sample ID herezr19514_153V1V3_R1.fastq.gzzr19514_153V1V3_R2.fastq.gz


F19514.S154original sample ID herezr19514_154V1V3_R1.fastq.gzzr19514_154V1V3_R2.fastq.gz


F19514.S155original sample ID herezr19514_155V1V3_R1.fastq.gzzr19514_155V1V3_R2.fastq.gz


F19514.S156original sample ID herezr19514_156V1V3_R1.fastq.gzzr19514_156V1V3_R2.fastq.gz


F19514.S157original sample ID herezr19514_157V1V3_R1.fastq.gzzr19514_157V1V3_R2.fastq.gz


F19514.S158original sample ID herezr19514_158V1V3_R1.fastq.gzzr19514_158V1V3_R2.fastq.gz


F19514.S159original sample ID herezr19514_159V1V3_R1.fastq.gzzr19514_159V1V3_R2.fastq.gz


F19514.S015original sample ID herezr19514_15V1V3_R1.fastq.gzzr19514_15V1V3_R2.fastq.gz


F19514.S160original sample ID herezr19514_160V1V3_R1.fastq.gzzr19514_160V1V3_R2.fastq.gz


F19514.S161original sample ID herezr19514_161V1V3_R1.fastq.gzzr19514_161V1V3_R2.fastq.gz


F19514.S162original sample ID herezr19514_162V1V3_R1.fastq.gzzr19514_162V1V3_R2.fastq.gz


F19514.S163original sample ID herezr19514_163V1V3_R1.fastq.gzzr19514_163V1V3_R2.fastq.gz


F19514.S164original sample ID herezr19514_164V1V3_R1.fastq.gzzr19514_164V1V3_R2.fastq.gz


F19514.S165original sample ID herezr19514_165V1V3_R1.fastq.gzzr19514_165V1V3_R2.fastq.gz


F19514.S166original sample ID herezr19514_166V1V3_R1.fastq.gzzr19514_166V1V3_R2.fastq.gz


F19514.S167original sample ID herezr19514_167V1V3_R1.fastq.gzzr19514_167V1V3_R2.fastq.gz


F19514.S168original sample ID herezr19514_168V1V3_R1.fastq.gzzr19514_168V1V3_R2.fastq.gz


F19514.S169original sample ID herezr19514_169V1V3_R1.fastq.gzzr19514_169V1V3_R2.fastq.gz


F19514.S016original sample ID herezr19514_16V1V3_R1.fastq.gzzr19514_16V1V3_R2.fastq.gz


F19514.S170original sample ID herezr19514_170V1V3_R1.fastq.gzzr19514_170V1V3_R2.fastq.gz


F19514.S171original sample ID herezr19514_171V1V3_R1.fastq.gzzr19514_171V1V3_R2.fastq.gz


F19514.S172original sample ID herezr19514_172V1V3_R1.fastq.gzzr19514_172V1V3_R2.fastq.gz


F19514.S173original sample ID herezr19514_173V1V3_R1.fastq.gzzr19514_173V1V3_R2.fastq.gz


F19514.S174original sample ID herezr19514_174V1V3_R1.fastq.gzzr19514_174V1V3_R2.fastq.gz


F19514.S175original sample ID herezr19514_175V1V3_R1.fastq.gzzr19514_175V1V3_R2.fastq.gz


F19514.S176original sample ID herezr19514_176V1V3_R1.fastq.gzzr19514_176V1V3_R2.fastq.gz


F19514.S177original sample ID herezr19514_177V1V3_R1.fastq.gzzr19514_177V1V3_R2.fastq.gz


F19514.S178original sample ID herezr19514_178V1V3_R1.fastq.gzzr19514_178V1V3_R2.fastq.gz


F19514.S179original sample ID herezr19514_179V1V3_R1.fastq.gzzr19514_179V1V3_R2.fastq.gz


F19514.S017original sample ID herezr19514_17V1V3_R1.fastq.gzzr19514_17V1V3_R2.fastq.gz


F19514.S180original sample ID herezr19514_180V1V3_R1.fastq.gzzr19514_180V1V3_R2.fastq.gz


F19514.S181original sample ID herezr19514_181V1V3_R1.fastq.gzzr19514_181V1V3_R2.fastq.gz


F19514.S182original sample ID herezr19514_182V1V3_R1.fastq.gzzr19514_182V1V3_R2.fastq.gz


F19514.S183original sample ID herezr19514_183V1V3_R1.fastq.gzzr19514_183V1V3_R2.fastq.gz


F19514.S184original sample ID herezr19514_184V1V3_R1.fastq.gzzr19514_184V1V3_R2.fastq.gz


F19514.S185original sample ID herezr19514_185V1V3_R1.fastq.gzzr19514_185V1V3_R2.fastq.gz


F19514.S186original sample ID herezr19514_186V1V3_R1.fastq.gzzr19514_186V1V3_R2.fastq.gz


F19514.S187original sample ID herezr19514_187V1V3_R1.fastq.gzzr19514_187V1V3_R2.fastq.gz


F19514.S188original sample ID herezr19514_188V1V3_R1.fastq.gzzr19514_188V1V3_R2.fastq.gz


F19514.S189original sample ID herezr19514_189V1V3_R1.fastq.gzzr19514_189V1V3_R2.fastq.gz


F19514.S018original sample ID herezr19514_18V1V3_R1.fastq.gzzr19514_18V1V3_R2.fastq.gz


F19514.S190original sample ID herezr19514_190V1V3_R1.fastq.gzzr19514_190V1V3_R2.fastq.gz


F19514.S191original sample ID herezr19514_191V1V3_R1.fastq.gzzr19514_191V1V3_R2.fastq.gz


F19514.S192original sample ID herezr19514_192V1V3_R1.fastq.gzzr19514_192V1V3_R2.fastq.gz


F19514.S193original sample ID herezr19514_193V1V3_R1.fastq.gzzr19514_193V1V3_R2.fastq.gz


F19514.S194original sample ID herezr19514_194V1V3_R1.fastq.gzzr19514_194V1V3_R2.fastq.gz


F19514.S195original sample ID herezr19514_195V1V3_R1.fastq.gzzr19514_195V1V3_R2.fastq.gz


F19514.S196original sample ID herezr19514_196V1V3_R1.fastq.gzzr19514_196V1V3_R2.fastq.gz


F19514.S197original sample ID herezr19514_197V1V3_R1.fastq.gzzr19514_197V1V3_R2.fastq.gz


F19514.S198original sample ID herezr19514_198V1V3_R1.fastq.gzzr19514_198V1V3_R2.fastq.gz


F19514.S199original sample ID herezr19514_199V1V3_R1.fastq.gzzr19514_199V1V3_R2.fastq.gz


F19514.S019original sample ID herezr19514_19V1V3_R1.fastq.gzzr19514_19V1V3_R2.fastq.gz


F19514.S001original sample ID herezr19514_1V1V3_R1.fastq.gzzr19514_1V1V3_R2.fastq.gz


F19514.S200original sample ID herezr19514_200V1V3_R1.fastq.gzzr19514_200V1V3_R2.fastq.gz


F19514.S201original sample ID herezr19514_201V1V3_R1.fastq.gzzr19514_201V1V3_R2.fastq.gz


F19514.S202original sample ID herezr19514_202V1V3_R1.fastq.gzzr19514_202V1V3_R2.fastq.gz


F19514.S203original sample ID herezr19514_203V1V3_R1.fastq.gzzr19514_203V1V3_R2.fastq.gz


F19514.S204original sample ID herezr19514_204V1V3_R1.fastq.gzzr19514_204V1V3_R2.fastq.gz


F19514.S205original sample ID herezr19514_205V1V3_R1.fastq.gzzr19514_205V1V3_R2.fastq.gz


F19514.S206original sample ID herezr19514_206V1V3_R1.fastq.gzzr19514_206V1V3_R2.fastq.gz


F19514.S207original sample ID herezr19514_207V1V3_R1.fastq.gzzr19514_207V1V3_R2.fastq.gz


F19514.S208original sample ID herezr19514_208V1V3_R1.fastq.gzzr19514_208V1V3_R2.fastq.gz


F19514.S209original sample ID herezr19514_209V1V3_R1.fastq.gzzr19514_209V1V3_R2.fastq.gz


F19514.S020original sample ID herezr19514_20V1V3_R1.fastq.gzzr19514_20V1V3_R2.fastq.gz


F19514.S210original sample ID herezr19514_210V1V3_R1.fastq.gzzr19514_210V1V3_R2.fastq.gz


F19514.S211original sample ID herezr19514_211V1V3_R1.fastq.gzzr19514_211V1V3_R2.fastq.gz


F19514.S212original sample ID herezr19514_212V1V3_R1.fastq.gzzr19514_212V1V3_R2.fastq.gz


F19514.S213original sample ID herezr19514_213V1V3_R1.fastq.gzzr19514_213V1V3_R2.fastq.gz


F19514.S214original sample ID herezr19514_214V1V3_R1.fastq.gzzr19514_214V1V3_R2.fastq.gz


F19514.S215original sample ID herezr19514_215V1V3_R1.fastq.gzzr19514_215V1V3_R2.fastq.gz


F19514.S216original sample ID herezr19514_216V1V3_R1.fastq.gzzr19514_216V1V3_R2.fastq.gz


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F19514.S095original sample ID herezr19514_95V1V3_R1.fastq.gzzr19514_95V1V3_R2.fastq.gz


F19514.S096original sample ID herezr19514_96V1V3_R1.fastq.gzzr19514_96V1V3_R2.fastq.gz


F19514.S097original sample ID herezr19514_97V1V3_R1.fastq.gzzr19514_97V1V3_R2.fastq.gz


F19514.S098original sample ID herezr19514_98V1V3_R1.fastq.gzzr19514_98V1V3_R2.fastq.gz


F19514.S099original sample ID herezr19514_99V1V3_R1.fastq.gzzr19514_99V1V3_R2.fastq.gz


F19514.S009original sample ID herezr19514_9V1V3_R1.fastq.gzzr19514_9V1V3_R2.fastq.gz


F.S000original sample ID herezr19514_R1.fastq.gzzr19514_R2.fastq.gz

Please download and save the file to your computer storage device. The download link will expire after 60 days upon your receiving of this report.

Raw sequence data download link:

 

VI. Analysis - DADA2 Read Processing

What is DADA2?

DADA2 is a software package that models and corrects Illumina-sequenced amplicon errors [1]. DADA2 infers sample sequences exactly, without coarse-graining into OTUs, and resolves differences of as little as one nucleotide. DADA2 identified more real variants and output fewer spurious sequences than other methods.

DADA2’s advantage is that it uses more of the data. The DADA2 error model incorporates quality information, which is ignored by all other methods after filtering. The DADA2 error model incorporates quantitative abundances, whereas most other methods use abundance ranks if they use abundance at all. The DADA2 error model identifies the differences between sequences, eg. A->C, whereas other methods merely count the mismatches. DADA2 can parameterize its error model from the data itself, rather than relying on previous datasets that may or may not reflect the PCR and sequencing protocols used in your study.

DADA2 Software Package is available as an R package at : https://benjjneb.github.io/dada2/index.html

References

  1. Callahan BJ, McMurdie PJ, Rosen MJ, Han AW, Johnson AJ, Holmes SP. DADA2: High-resolution sample inference from Illumina amplicon data. Nat Methods. 2016 Jul;13(7):581-3. doi: 10.1038/nmeth.3869. Epub 2016 May 23. PMID: 27214047; PMCID: PMC4927377.

Analysis Procedures:

DADA2 pipeline includes several tools for read quality control, including quality filtering, trimming, denoising, pair merging and chimera filtering. Below are the major processing steps of DADA2:

Step 1. Read trimming based on sequence quality The quality of NGS Illumina sequences often decreases toward the end of the reads. DADA2 allows to trim off the poor quality read ends in order to improve the error model building and pair mergicing performance.

Step 2. Learn the Error Rates The DADA2 algorithm makes use of a parametric error model (err) and every amplicon dataset has a different set of error rates. The learnErrors method learns this error model from the data, by alternating estimation of the error rates and inference of sample composition until they converge on a jointly consistent solution. As in many machine-learning problems, the algorithm must begin with an initial guess, for which the maximum possible error rates in this data are used (the error rates if only the most abundant sequence is correct and all the rest are errors).

Step 3. Infer amplicon sequence variants (ASVs) based on the error model built in previous step. This step is also called sequence "denoising". The outcome of this step is a list of ASVs that are the equivalent of oligonucleotides.

Step 4. Merge paired reads. If the sequencing products are read pairs, DADA2 will merge the R1 and R2 ASVs into single sequences. Merging is performed by aligning the denoised forward reads with the reverse-complement of the corresponding denoised reverse reads, and then constructing the merged “contig” sequences. By default, merged sequences are only output if the forward and reverse reads overlap by at least 12 bases, and are identical to each other in the overlap region (but these conditions can be changed via function arguments).

Step 5. Remove chimera. The core dada method corrects substitution and indel errors, but chimeras remain. Fortunately, the accuracy of sequence variants after denoising makes identifying chimeric ASVs simpler than when dealing with fuzzy OTUs. Chimeric sequences are identified if they can be exactly reconstructed by combining a left-segment and a right-segment from two more abundant “parent” sequences. The frequency of chimeric sequences varies substantially from dataset to dataset, and depends on on factors including experimental procedures and sample complexity.

Results

1. Read Quality Plots NGS sequence analaysis starts with visualizing the quality of the sequencing. Below are the quality plots of the first sample for the R1 and R2 reads separately. In gray-scale is a heat map of the frequency of each quality score at each base position. The mean quality score at each position is shown by the green line, and the quartiles of the quality score distribution by the orange lines. The forward reads are usually of better quality. It is a common practice to trim the last few nucleotides to avoid less well-controlled errors that can arise there. The trimming affects the downstream steps including error model building, merging and chimera calling. FOMC uses an empirical approach to test many combinations of different trim length in order to achieve best final amplicon sequence variants (ASVs), see the next section “Optimal trim length for ASVs”.

Quality plots for all samples:

2. Optimal trim length for ASVs The final number of merged and chimera-filtered ASVs depends on the quality filtering (hence trimming) in the very beginning of the DADA2 pipeline. In order to achieve highest number of ASVs, an empirical approach was used -

  1. Create a random subset of each sample consisting of 5,000 R1 and 5,000 R2 (to reduce computation time)
  2. Trim 10 bases at a time from the ends of both R1 and R2 up to 50 bases
  3. For each combination of trimmed length (e.g., 300x300, 300x290, 290x290 etc), the trimmed reads are subject to the entire DADA2 pipeline for chimera-filtered merged ASVs
  4. The combination with highest percentage of the input reads becoming final ASVs is selected for the complete set of data

Below is the result of such operation, showing ASV percentages of total reads for all trimming combinations (1st Column = R1 lengths in bases; 1st Row = R2 lengths in bases):

R1/R2281271261251241231
32180.60%80.84%81.05%81.48%81.79%75.28%
31180.65%80.89%81.11%81.36%75.33%48.93%
30180.67%80.91%80.95%74.86%48.97%23.14%
29180.75%80.81%74.53%48.55%23.15%15.07%
28180.77%74.49%48.59%22.87%15.05%8.05%
27174.68%48.89%22.97%14.77%8.00%3.98%

Based on the above result, the trim length combination of R1 = 321 bases and R2 = 241 bases (highlighted red above), was chosen for generating final ASVs for all sequences. This combination generated highest number of merged non-chimeric ASVs and was used for downstream analyses, if requested.

3. Error plots from learning the error rates After DADA2 building the error model for the set of data, it is always worthwhile, as a sanity check if nothing else, to visualize the estimated error rates. The error rates for each possible transition (A→C, A→G, …) are shown below. Points are the observed error rates for each consensus quality score. The black line shows the estimated error rates after convergence of the machine-learning algorithm. The red line shows the error rates expected under the nominal definition of the Q-score. The ideal result would be the estimated error rates (black line) are a good fit to the observed rates (points), and the error rates drop with increased quality as expected.

Forward Read R1 Error Plot


Reverse Read R2 Error Plot

The PDF version of these plots are available here:

 

4. DADA2 Result Summary The table below shows the summary of the DADA2 analysis, tracking paired read counts of each samples for all the steps during DADA2 denoising process - including end-trimming (filtered), denoising (denoisedF, denoisedF), pair merging (merged) and chimera removal (nonchim).

Sample IDF19514.S001F19514.S002F19514.S003F19514.S004F19514.S005F19514.S006F19514.S007F19514.S008F19514.S009F19514.S010F19514.S011F19514.S012F19514.S013F19514.S014F19514.S015F19514.S016F19514.S017F19514.S018F19514.S019F19514.S020F19514.S021F19514.S022F19514.S023F19514.S024F19514.S025F19514.S026F19514.S027F19514.S028F19514.S029F19514.S030F19514.S031F19514.S032F19514.S033F19514.S034F19514.S035F19514.S036F19514.S037F19514.S038F19514.S039F19514.S040F19514.S041F19514.S042F19514.S043F19514.S044F19514.S045F19514.S046F19514.S047F19514.S048F19514.S049F19514.S050F19514.S051F19514.S052F19514.S053F19514.S054F19514.S055F19514.S056F19514.S057F19514.S058F19514.S059F19514.S060F19514.S061F19514.S062F19514.S063F19514.S064F19514.S065F19514.S066F19514.S067F19514.S068F19514.S069F19514.S070F19514.S071F19514.S072F19514.S073F19514.S074F19514.S075F19514.S076F19514.S077F19514.S078F19514.S079F19514.S080F19514.S081F19514.S082F19514.S083F19514.S084F19514.S085F19514.S086F19514.S087F19514.S088F19514.S089F19514.S090F19514.S091F19514.S092F19514.S093F19514.S094F19514.S095F19514.S096F19514.S097F19514.S098F19514.S099F19514.S100F19514.S101F19514.S102F19514.S103F19514.S104F19514.S105F19514.S106F19514.S107F19514.S108F19514.S109F19514.S110F19514.S111F19514.S112F19514.S113F19514.S114F19514.S115F19514.S116F19514.S117F19514.S118F19514.S119F19514.S120F19514.S121F19514.S122F19514.S123F19514.S124F19514.S125F19514.S126F19514.S127F19514.S128F19514.S129F19514.S130F19514.S131F19514.S132F19514.S133F19514.S134F19514.S135F19514.S136F19514.S137F19514.S138F19514.S139F19514.S140F19514.S141F19514.S142F19514.S143F19514.S144F19514.S145F19514.S146F19514.S147F19514.S148F19514.S149F19514.S150F19514.S151F19514.S152F19514.S153F19514.S154F19514.S155F19514.S156F19514.S157F19514.S158F19514.S159F19514.S160F19514.S161F19514.S162F19514.S163F19514.S164F19514.S165F19514.S166F19514.S167F19514.S168F19514.S169F19514.S170F19514.S171F19514.S172F19514.S173F19514.S174F19514.S175F19514.S176F19514.S177F19514.S178F19514.S179F19514.S180F19514.S181F19514.S182F19514.S183F19514.S184F19514.S185F19514.S186F19514.S187F19514.S188F19514.S189F19514.S190F19514.S191F19514.S192F19514.S193F19514.S194F19514.S195F19514.S196F19514.S197F19514.S198F19514.S199F19514.S200F19514.S201F19514.S202F19514.S203F19514.S204F19514.S205F19514.S206F19514.S207F19514.S208F19514.S209F19514.S210F19514.S211F19514.S212F19514.S213F19514.S214F19514.S215F19514.S216F19514.S217F19514.S218F19514.S219F19514.S220F19514.S221F19514.S222F19514.S223F19514.S224F19514.S225F19514.S226F19514.S227F19514.S228F19514.S229F19514.S230F19514.S231F19514.S232F19514.S233F19514.S234F19514.S235F19514.S236F19514.S237F19514.S238F19514.S239F19514.S240F19514.S241F19514.S242F19514.S243F19514.S244F19514.S245F19514.S246F19514.S247F19514.S248F19514.S249F19514.S250F19514.S251F19514.S252F19514.S253F19514.S254F19514.S255F19514.S256F19514.S257F19514.S258F19514.S259F19514.S260F19514.S261F19514.S262F19514.S263F19514.S264F19514.S265F19514.S266F19514.S267F19514.S268F19514.S269F19514.S270F19514.S271F19514.S272F19514.S273F19514.S274F19514.S275F19514.S276F19514.S277F19514.S278F19514.S279F19514.S280F19514.S281F19514.S282F19514.S283F19514.S284F19514.S285F19514.S286F19514.S287F19514.S288F19514.S289F19514.S290F19514.S291F19514.S292F19514.S293F19514.S294F19514.S295F19514.S296F19514.S297F19514.S298F19514.S299F19514.S300F19514.S301F19514.S302F19514.S303F19514.S304F19514.S305F19514.S306F19514.S307F19514.S308F19514.S309F19514.S310F19514.S311F19514.S312F19514.S313F19514.S314F19514.S315F19514.S316F19514.S317F19514.S318F19514.S319F19514.S320F19514.S321F19514.S322F19514.S323F19514.S324F19514.S325F19514.S326F19514.S327F19514.S328F19514.S329F19514.S330F19514.S331F19514.S332F19514.S333F19514.S334F19514.S335F19514.S336F19514.S337F19514.S338F19514.S339F19514.S340F19514.S341F19514.S342F19514.S343F19514.S344F19514.S345F19514.S346F19514.S347F19514.S348F19514.S349F19514.S350F19514.S351F19514.S352F19514.S353F19514.S354F19514.S355F19514.S356F19514.S357F19514.S358F19514.S359F19514.S360F19514.S361F19514.S362F19514.S363F19514.S364F19514.S365F19514.S366F19514.S367F19514.S368F19514.S369F19514.S370F19514.S371F19514.S372F19514.S373F19514.S374F19514.S375F19514.S376F19514.S377F19514.S378F19514.S379F19514.S380F19514.S381F19514.S382F19514.S383F19514.S384F19514.S385F19514.S386F19514.S387F19514.S388F19514.S389F19514.S390F19514.S391F19514.S392F19514.S393F19514.S394F19514.S395F19514.S396F19514.S397F19514.S398F19514.S399F19514.S400F19514.S401F19514.S402F19514.S403F19514.S404F19514.S405F19514.S406F19514.S407F19514.S408F19514.S409F19514.S410F19514.S411F19514.S412F19514.S413F19514.S414F19514.S415F19514.S416F19514.S417F19514.S418F19514.S419F19514.S420F19514.S421F19514.S422F19514.S423F19514.S424F19514.S425F19514.S426F19514.S427F19514.S428F19514.S429F19514.S430F19514.S431F19514.S432F19514.S433F19514.S434F19514.S435F19514.S436F19514.S437F19514.S438F19514.S439F19514.S440F19514.S441F19514.S442F19514.S443F19514.S444F19514.S445F19514.S446F19514.S447F19514.S448F19514.S449F19514.S450F19514.S451F19514.S452F19514.S453F19514.S454F19514.S455F19514.S456F19514.S457F19514.S458F19514.S459F19514.S460F19514.S461F19514.S462F19514.S463F19514.S464F19514.S465F19514.S466F19514.S467F19514.S468F19514.S469F19514.S470F19514.S471F19514.S472F19514.S473F19514.S474F19514.S475F19514.S476F19514.S477F19514.S478F19514.S479F19514.S480F19514.S481F19514.S482F19514.S483F19514.S484F19514.S485F19514.S486F19514.S487F19514.S488F19514.S489F19514.S490F19514.S491F19514.S492F19514.S493F19514.S494F19514.S495F19514.S496F19514.S497F19514.S498F19514.S499F19514.S500F19514.S501F19514.S502F19514.S503F19514.S504F19514.S505F19514.S506F19514.S507F19514.S508F19514.S509F19514.S510F19514.S511F19514.S512F19514.S513F19514.S514F19514.S515F19514.S516F19514.S517F19514.S518F19514.S519F19514.S520F19514.S521F19514.S522F19514.S523F19514.S524F19514.S525F19514.S526F19514.S527F19514.S528F19514.S529F19514.S530F19514.S531F19514.S532F19514.S533F19514.S534F19514.S535F19514.S536F19514.S537F19514.S538F19514.S539F19514.S540F19514.S541F19514.S542F19514.S543F19514.S544F19514.S545F19514.S546F19514.S547F19514.S548F19514.S549F19514.S550F19514.S551F19514.S552F19514.S553F19514.S554F19514.S555F19514.S556F19514.S557F19514.S558F19514.S559F19514.S560F19514.S561F19514.S562F19514.S563F19514.S564F19514.S565F19514.S566F19514.S567F19514.S568F19514.S569F19514.S570F19514.S571F19514.S572F19514.S573F19514.S574F19514.S575F19514.S576F19514.S577F19514.S578F19514.S579F19514.S580F19514.S581F19514.S582F19514.S583F19514.S584F19514.S585F19514.S586F19514.S587F19514.S588F19514.S589F19514.S590F19514.S591F19514.S592F19514.S593F19514.S594F19514.S595F19514.S596F19514.S597F19514.S598F19514.S599F19514.S600F19514.S601F19514.S602F19514.S603F19514.S604F19514.S605F19514.S606F19514.S607F19514.S608F19514.S609F19514.S610F19514.S611F19514.S612F19514.S613F19514.S614F19514.S615F19514.S616F19514.S617F19514.S618F19514.S619F19514.S620F19514.S621F19514.S622F19514.S623F19514.S624F19514.S625F19514.S626F19514.S627F19514.S628F19514.S629F19514.S630Row SumPercentage
input57,41979,97972,44848,27155,86562,43462,96455,55158,41956,79356,99859,33063,74848,00364,42451,01653,63249,70454,65368,56376,83340,23264,62967,00250,40365,05664,22564,11055,60664,56952,86760,41752,55948,88564,14070,71761,30350,68052,36056,97366,89347,38859,14257,67474,18467,20753,19061,07373,84763,14367,91463,09262,27273,43962,30665,15566,86758,15870,07453,48871,64072,08967,81359,73084,30158,72279,80996,392123,77475,94753,86156,82571,85262,14896,11657,93860,61053,51763,04159,83651,19078,94666,31161,09663,40775,41764,49565,41668,81266,14249,12674,90059,53160,73962,10959,09358,75163,38365,50364,38361,03552,26163,48156,92359,11853,66158,13161,26464,86763,72667,48065,28052,18962,25863,09664,04875,30664,08967,47963,37357,52560,21968,94561,28451,17565,61762,60059,14759,29462,88054,14460,94573,94153,48076,28559,13165,68759,57264,00758,24875,54163,31471,28250,67066,89658,03564,59257,16267,51061,36356,81265,05655,44661,24749,18455,04372,40660,86562,15549,68358,38359,63266,71458,50758,36559,90764,34447,04952,73158,43054,43762,07270,29657,16152,99365,52862,48271,18262,12257,67559,89657,82874,00852,61259,32657,70857,69761,90654,25959,40145,11163,64763,48746,55568,99549,77055,71367,86759,20652,45763,39274,30933,74659,45856,88547,84165,85453,38962,16574,69859,47346,67855,21358,86447,95161,73072,19651,79262,94675,18557,82353,65357,53649,68649,62259,36555,31462,43259,38460,86368,06654,39782,98563,72877,50674,49955,05062,55460,04249,04975,07558,38160,59441,12050,53464,62632,21849,83976,72248,79959,08352,93261,72953,95362,68647,48458,21159,88658,77779,52949,30260,39664,81160,81482,90065,06759,26262,13968,89453,44990,71362,03171,59870,97375,53253,20059,28866,04561,12560,61268,71461,96667,07258,38762,55368,56570,98456,49361,04957,89363,90567,25164,33665,43171,26372,07262,80759,50461,94960,56182,21264,56761,72367,74990,05379,70166,76849,73265,38355,08982,70271,62271,05274,69562,92564,61962,96876,47650,24368,68165,15770,28069,50366,50963,78461,39654,86361,82771,28860,25656,22556,95169,30268,32760,64873,50251,73863,87062,17459,35662,19763,98858,32158,63675,16451,28657,90656,61353,03652,54570,91362,51258,86956,99562,74953,08052,43651,47950,59857,75862,66157,91880,35949,85545,98828,16574,41355,57176,40266,63858,12947,66054,99458,24578,66655,57253,96267,09150,01931,90652,20456,50251,06437,17965,82856,95834,51085,09249,39947,16163,53876,56948,26579,66960,78568,20128,13462,92566,39166,31693,05380,46156,34748,49342,09650,66536,24663,66053,05626,612100,42161,68543,69961,52158,35247,96987,26262,06450,12564,91756,17878,48074,65261,44053,72494,80158,72860,11944,64983,23938,69652,18764,97471,92251,28453,94464,66550,02175,66773,375118,74063,12544,77947,66858,31060,35164,26932,86052,06172,36961,37656,82556,49179,45559,40573,13276,93376,24656,68678,82944,87668,64068,82160,84789,69151,85454,9566,18363,59659,43077,21479,59039,60185,05170,30844,01278,46864,07349,64593,37752,12355,27451,75843,65972,67169,98277,14257,64650,15452,14879,92965,95615,01750,93271,63073,19370,30349,79378,65370,83252,42553,356100,28070,70339,08169,68248,92949,54865,62149,77265,30358,17239,98475,67876,33487,72772,75068,65881,52276,14256,06939,72659,31263,98466,51080,14175,42679,04857,88245,01062,57255,00991,17773,37746,73174,24653,47154,13468,30763,24638,53457,83955,65964,96761,96088,14259,80766,74868,64958,06268,52460,75053,66572,31764,72294,84878,02370,11979,56066,76738,45557,67850,71975,74272,81668,99341,97741,67047,57673,86073,59360,71654,37061,87163,73936,50658,52267,09975,64965,84946,37087,65762,27946,93271,33786,02448,67064,72143,78577,45462,01464,66679,04960,41050,78563,27035,60376,24647,12337,48547,81481,31758,32582,90074,11275,85283,22156,05823,35363,56979,15448,42086,19031,51873,08559,22174,30431,49059,51554,40957,33349,90449,14349,09447,08359,73761,16259,47765,67052,99038,936,007100.00%
filtered57,41679,97872,44748,27055,86362,43362,96155,55158,41856,79356,99859,32963,74748,00264,42351,01653,63249,70354,65168,56376,83240,23064,62966,99950,40265,05464,22364,11055,60464,56952,86760,41652,55848,88464,13870,71761,30150,67952,35956,97366,89047,38859,14257,67174,18467,20753,18861,07173,84463,14267,91463,09162,27273,43862,30665,15266,86758,15870,07353,48871,63972,08867,81259,73084,29958,72179,80796,387123,77275,94453,85756,82571,85162,14796,11657,93760,60953,51563,03859,83451,19078,94666,31061,09663,40775,41764,49465,41668,81266,14149,12574,89959,53060,73762,10859,09358,75063,38265,50364,38161,03452,26163,48056,92259,11753,66158,12961,26464,86463,72567,48065,28052,18862,25763,09564,04675,30664,08967,47863,37357,52560,21968,94361,28451,17265,61662,59859,14659,29362,87754,14260,94573,94053,48076,28359,13065,68759,57064,00658,24875,53963,31371,28250,66766,89458,03464,59257,16167,50861,36256,81265,05455,44561,24749,18355,04272,40660,86462,15549,68358,38259,63266,71258,50758,36459,90564,34147,04952,72958,42854,43762,07070,29357,16152,99365,52562,48171,18262,12157,67259,89557,82774,00852,61159,32457,70857,69761,90554,25859,40045,11163,64663,48746,55568,99349,76955,71367,86659,20352,45663,39274,30933,74659,45556,88547,83965,85353,38862,16574,69659,47246,67655,21258,86347,95061,73072,19651,79162,94575,18257,82253,65357,53649,68649,62059,36555,31462,42859,38460,86368,06654,39582,98563,72677,50474,49755,04862,55460,04249,04775,07358,37960,59441,11950,53364,62632,21849,83976,72148,79759,08352,92961,72953,95262,68447,48458,20959,88658,77679,52749,30160,39564,81160,81382,89965,06759,26062,13968,89353,44990,71262,03071,59770,97275,53153,20059,28866,04361,12560,61168,71461,96667,07258,38762,55168,56570,98456,49061,04957,89263,90467,25064,33365,42871,26272,07162,80759,50461,94960,56082,21164,56561,72367,74990,05079,69866,76749,73165,38055,08982,70071,62071,05174,69462,92564,61862,96776,47650,24368,67965,15770,28069,50266,50963,78361,39654,86361,82571,28760,25556,22556,95069,30168,32360,64773,50051,73863,87062,17459,35662,19763,98558,31758,63675,16351,28457,90456,61353,03552,54570,91162,50958,86756,99562,74753,08052,43551,47850,59857,75762,66157,91680,35849,85445,98628,16474,41355,57076,40066,63858,12747,66054,99358,24478,66455,57253,96267,08950,01831,90552,20356,49951,06437,17865,82556,95834,51085,09149,39747,16163,53676,56748,26579,66960,78568,20028,13462,92566,38866,31593,05280,45856,34648,49342,09550,66536,24563,65853,05326,612100,41961,68343,69961,52058,35047,96987,26262,06250,12464,91656,17678,47974,65061,43853,72494,80158,72660,11844,64983,23638,69652,18264,97471,92251,28253,94264,66250,02175,66673,375118,73863,12444,77847,66858,30960,35164,26832,86052,06072,36961,37656,82256,48979,45259,40573,13176,93276,24456,68378,82944,87668,64068,82160,84689,68851,85454,9556,18363,59559,42977,21379,58839,60085,04970,30744,01278,46764,07049,64593,37452,12255,27351,75643,65872,66769,98077,13957,64650,15252,14779,92765,95515,01750,92771,62773,19170,30249,79178,65370,83252,42453,354100,27870,70339,08169,67948,92749,54765,61849,77065,30358,16939,98375,67776,33387,72672,75068,65581,52076,13956,06739,72559,30963,98366,50880,14075,42679,04757,88045,00862,57155,00891,17473,37646,73074,24653,46954,13368,30663,24338,53357,83755,65964,96561,95988,14159,80766,74468,64758,06268,52360,74953,66372,31564,72194,84678,02170,11679,55966,76738,45457,67850,71875,74172,81668,99241,97741,66947,57673,85973,59160,71654,37061,87163,73736,50658,52267,09875,64865,84546,36887,65662,27946,93071,33786,02248,67064,71943,78377,45362,01364,66679,04860,40750,78563,26935,60276,24647,12237,48547,81481,31658,32382,89974,11175,85183,22156,05823,35363,56979,15348,41886,18731,51873,08459,21874,30331,48959,51554,40657,33149,90349,14349,09247,08259,73661,16159,47665,66852,98938,935,322100.00%
denoisedF56,75179,28371,72547,70354,90961,58262,15955,00857,82556,19456,38658,41662,76247,25063,66450,40453,09349,14454,13267,61476,11239,88663,81966,13949,79664,34063,48563,32054,64163,83252,24559,54651,67248,26763,46269,75760,68450,08251,83956,29266,22546,94258,43857,16173,36366,58452,42560,28773,11462,48867,01962,29061,52272,43761,63864,38465,94157,44369,35252,90870,78970,73566,90558,99783,43958,13179,04795,291122,71375,00953,33056,31070,92761,31295,10157,11759,74652,66162,49859,29850,42777,95665,71560,45762,43574,57563,62264,73968,20065,18648,31974,15358,68560,07161,50158,58857,92362,62564,95263,71560,25951,79162,90556,16558,31152,99057,40460,59064,23663,02866,71664,39751,63961,54962,29963,02674,59763,46166,71362,74156,53259,59167,90960,70150,64464,93461,93558,38058,78362,00153,41360,20773,18652,88975,78858,46164,83558,75363,10157,71774,77162,69870,61050,16566,21257,15263,83056,48566,64760,56956,14864,33354,85960,62448,80554,19071,51160,10861,27449,30357,89759,19765,85457,67057,58559,26463,77646,51852,17857,59953,67461,05169,31256,38452,40464,84161,74870,36761,60257,09159,25857,28472,95151,99258,60856,87657,06361,25053,54358,69044,40362,68762,74746,08767,88149,21155,02667,19458,52151,82062,61073,65033,19258,87256,34747,23265,26052,71061,11974,04458,92146,15454,57758,33047,38561,02271,39851,11162,10474,40957,20152,98156,78849,13148,93758,66154,80961,77358,82060,15067,37653,61881,98862,88776,68573,85254,48261,76159,08548,47574,33657,56259,87040,60449,68263,84331,82249,17575,88648,28858,26652,23361,05953,44561,88846,84357,53659,35658,05878,79848,72559,77863,97659,95582,22864,44158,33761,53768,21752,95989,66661,32070,78270,10474,83752,58858,57165,42560,18259,75467,87761,45966,25557,61261,74767,83570,46055,83960,37757,30763,19166,65463,71864,71370,58471,24662,20158,80661,33359,89681,38363,91861,06766,97189,08578,57066,15949,02864,36554,54281,90470,88770,38773,78362,47163,95562,41075,88549,77568,27564,53969,37669,03766,07663,21860,83154,07761,11270,60559,54355,74456,30868,52267,59060,16572,75451,20763,51361,51958,97561,52863,30857,73157,92974,59050,82357,35056,11952,26151,86370,43761,87658,32856,24162,24652,61551,73250,84750,26057,28361,96257,41479,65349,26545,40327,83173,54354,92375,73065,89757,63147,20154,37457,55177,95054,77253,40166,23849,44231,46651,73155,90250,42336,90365,33856,45234,15584,65049,04146,47362,65875,61947,58479,10360,22767,48727,63562,23865,59465,48292,04979,79055,85647,87941,62650,10335,83862,93052,34326,29099,98160,97242,88860,83457,76147,57486,43961,43949,48364,17355,52777,71873,72560,92053,27794,01458,33159,41944,17182,62938,22651,50064,51071,27250,48753,52663,79949,37974,85872,390117,71962,34243,98746,92657,60959,73763,69232,39951,49671,82460,46456,08355,88678,28458,69072,49276,24675,59856,07478,10544,10467,76867,97460,31688,82151,21554,1236,00962,98158,88375,75978,73939,15584,06069,65643,51277,98563,33648,96093,03551,66954,72351,29943,38371,88869,32576,15157,08349,42951,50879,38665,33414,77550,39171,38972,34969,81349,00877,83569,91451,68152,86899,59069,98038,53068,72548,34449,14165,06149,47564,52257,45539,50474,70775,86186,89272,15767,83780,77575,43555,47239,32158,82563,19966,14179,47574,95778,62557,08244,67661,83454,75190,14172,74046,33073,56352,83953,38667,78862,59038,10257,42755,11864,57061,67787,39958,97665,98467,91257,71667,89960,48853,20471,63764,26994,13777,31269,47679,01065,94438,04256,95150,25074,89372,16068,57441,58641,27147,23373,41573,22360,15153,92061,25263,17836,07458,00866,31574,91865,26045,99386,77561,92946,49571,05685,41048,32464,04843,10976,58461,25563,69978,27459,73750,12562,62135,01475,52646,76936,80147,26180,90057,94982,08773,32175,21182,47755,54123,11162,73078,38047,83885,77931,17172,60058,79673,74231,09058,77453,88757,09449,39648,38848,38246,50159,25360,72058,85664,87952,48238,516,51398.92%
denoisedR56,67579,15671,61647,71755,14061,57362,11454,84757,56256,01456,23558,50862,87847,27863,55450,13953,04949,08753,95267,61476,00639,83563,82166,06649,62564,24463,38463,21954,64563,62452,23759,61851,89448,12563,37669,75560,62950,02751,72556,32866,22446,66558,35857,06773,36066,48752,55360,38473,00762,39566,97962,17861,54072,47661,55964,31266,05257,12269,02152,74470,81771,04466,91059,07583,58858,07378,70095,086122,69274,99053,21856,12971,02961,19295,18457,26259,87052,67762,35859,13450,69778,03965,51260,33062,48774,61363,53464,78567,96265,23148,32474,04658,68560,07861,37558,61958,07862,61364,84063,73160,13451,68262,72956,32558,35553,05157,46260,64664,12962,89566,66964,60851,60961,49562,43462,97174,65363,32566,75262,66956,52159,43267,96560,35650,40764,86561,54658,24058,62562,06353,31659,97672,96552,76475,68158,39064,87258,75063,23857,43874,67062,57370,58649,86666,16457,10563,70156,55766,68860,56956,15564,17154,65460,43848,62054,24371,59660,05161,43449,09157,73459,07265,88657,73557,56059,20463,58946,38052,05057,80753,69161,18169,40156,40352,26764,83761,76070,22661,46456,87059,22257,16173,18851,96958,56056,96557,03761,12953,59558,71944,46162,83662,74745,89668,19149,17754,90667,03758,39351,73562,70073,61333,30258,73656,25247,24865,15252,80361,27774,12258,52946,01254,53558,21047,38960,98571,50851,26162,14874,32857,13852,93656,64648,80848,87058,62354,85361,77658,47060,24467,28953,74082,00562,85176,78773,79454,39961,74259,22748,32574,34257,44359,79440,43949,68763,58331,70149,30575,76148,12558,14152,24961,05753,38062,16346,96557,31059,36558,01678,85948,65159,66363,89460,15281,99964,30658,46761,28067,99752,79289,76261,29270,77770,04374,74752,35358,55465,41459,83259,91967,92661,32866,30257,58861,75967,69070,29555,82260,02457,19863,13866,38463,58164,66470,23471,29062,02858,64360,98059,81681,47363,70861,03966,81289,02078,91866,26549,15364,18554,37081,97170,70770,19973,67162,43263,96662,09275,59149,49768,13664,24769,23468,92565,73262,94060,49254,00560,95970,44459,48055,35656,19368,35667,38060,04472,75551,11763,39761,16658,84761,31263,18957,50457,67074,25250,69757,28556,03052,22651,84170,42061,63358,12656,01862,16652,25551,70450,61549,95857,25361,72957,33979,38348,75845,24627,70673,31054,75675,63665,74757,55646,93854,15257,47777,80154,72553,29466,16349,42231,37151,62755,71250,26936,82765,22756,10834,03684,54248,97146,11862,59375,71747,52279,06960,02867,54327,46161,99865,37065,34691,95879,57655,74447,44241,50049,77535,74962,67852,09326,08499,80660,87042,81660,57057,74947,34085,87161,15849,47763,78355,53477,64073,54260,61353,14793,52958,27359,29444,10882,36438,08451,42264,39071,32350,47053,47563,65849,39074,59372,091117,27162,25043,88346,75457,30559,59163,39932,14551,33171,67760,39656,03555,61178,37458,74572,42576,16775,58855,97077,90344,05067,50767,97660,26888,58151,07353,9695,99862,84858,81976,20478,61338,96584,17669,33043,36577,86063,05048,72192,58751,40154,46951,18043,26971,71169,24675,87657,04749,29950,88179,16665,11214,80850,43071,25472,09969,64348,85477,94269,87651,47752,65499,33669,94538,40368,76348,34148,97964,76949,45064,24557,41539,39474,59075,58686,65871,88667,81280,67975,36655,49339,19958,80163,15166,04079,31974,84378,51357,16744,68361,72554,61189,89872,59646,33373,15052,68153,34167,75662,39037,88457,41955,03164,25561,58387,21458,70065,79167,95257,74567,78960,33853,08771,36964,01494,03076,75569,36178,72865,68337,96656,76450,13574,74872,04768,55841,10941,04247,08373,25573,11359,96253,89061,07763,09535,81957,82766,30174,68665,05845,80586,48061,89346,16070,95685,31248,23463,68142,79376,39260,94363,57277,98359,50250,14162,53934,80775,27746,66936,67647,23080,70757,71381,90273,15274,99481,96155,36423,09762,35978,24347,69685,59731,04072,50258,64573,58030,98658,79353,87656,97049,22848,32148,13846,51859,23160,50858,83064,95352,32138,452,17398.76%
merged53,10475,18268,25444,98451,86157,88858,27951,77753,95452,60753,35854,85758,72043,89659,95346,66550,48646,36751,13563,42272,36637,89960,39062,30245,90860,78759,52759,36250,78360,05549,21155,78248,59744,63459,54365,32157,34346,82948,69553,09162,29544,01654,83354,32169,77463,06649,53657,04868,64259,03963,11758,13957,52468,03557,84860,70761,93753,15365,23549,74367,12565,36362,80355,78679,56954,73874,05988,268116,54070,52549,90353,07967,42757,15992,28253,89756,45649,24659,52256,68547,95573,50962,03957,11458,68371,02659,25061,31663,13660,41244,99170,10454,38656,88957,97455,79654,62059,19061,86460,07056,49249,06558,99853,20954,72850,18854,23157,38660,52658,89763,00960,96248,74758,19658,66358,97670,56860,23462,56659,44452,63755,88363,38457,08147,06761,39457,94154,11355,74258,45549,79955,83268,57349,77672,69955,06660,83055,21159,91554,04970,62759,01967,08747,13862,44853,19059,56453,58062,60156,75052,71360,64251,90156,89246,27950,65467,58356,10657,36346,62754,82856,69561,91853,71554,36355,79459,90643,75249,56754,23950,41057,24865,02652,68149,52961,95258,23466,54258,08353,73756,23554,01168,52048,93754,80553,49253,47657,52550,43055,67241,38359,63759,51342,93464,25646,79251,62663,33855,19248,92359,33470,03930,95255,54853,60844,35061,70849,96056,80671,55955,00443,03751,27555,10744,49757,60667,74848,17458,20070,41454,07349,71153,16045,66245,23555,04952,38458,62055,03157,12563,65450,13077,09659,21873,57970,05151,45657,95755,76445,23470,53553,74156,45137,94146,55259,41329,61146,60971,75145,09953,73948,90357,60850,52759,23044,17953,78756,63554,81275,30545,52756,82760,24756,70178,13061,12654,96757,47464,17750,13484,68957,54666,59765,85570,89249,08255,20262,08855,73756,58164,03558,28262,14254,27858,15664,15067,98952,91656,50954,35359,72863,15560,78661,34566,12567,48758,74455,30857,79156,64277,85159,91157,95963,43284,37874,62263,53946,13759,68151,51378,05467,13667,25369,00960,42861,10358,27871,40745,57665,86560,25864,29866,07862,05259,12156,21549,90356,59666,65955,59551,79952,37163,48061,79056,45868,52548,16661,10956,10656,34956,48059,44453,74153,59367,61148,11254,23452,42347,98948,01667,48455,37854,40451,45958,35648,21947,46745,18247,10754,33456,43854,44074,62444,46142,08325,48467,47850,28970,77661,31454,49843,20150,08653,66672,40850,43349,75760,93846,11428,88748,20952,22945,90235,00461,37152,31131,02781,00946,37241,90857,82070,51343,34775,63156,07663,72624,66357,75660,22360,69685,93474,94952,79842,95338,70145,09928,45058,16847,61623,88496,88056,71338,69555,45754,08144,32380,12956,90545,82258,07651,98360,56768,06856,91149,94787,75455,77254,81641,26377,79135,24745,47161,26667,87145,93650,97858,09345,38769,56366,373109,93957,83739,79342,39452,37555,90858,98728,91247,23867,93155,31551,90551,12370,86054,56668,25671,50172,84252,31672,84839,60461,70363,07056,93382,45446,67149,1845,28259,22954,68769,84273,34834,75478,49164,48538,35675,03558,44744,07490,45748,03150,71448,23541,19767,03265,55869,55453,61344,95846,29375,84161,10013,60147,60469,43866,18766,32744,06073,80564,54547,20146,92795,18665,36735,10063,60044,68746,05261,16047,43358,94451,65336,17568,69968,39680,31568,45663,31276,51570,65151,89936,34755,57757,36563,24073,98971,80075,58053,11542,98557,08452,64082,99368,45144,17468,03048,67849,71064,17057,94435,12954,86451,71560,99859,98681,93853,22061,42463,82355,91163,84858,74350,50566,26360,01489,32070,57665,79274,74260,82035,29552,09147,35069,71368,09366,10237,60838,48344,88470,74870,65856,27951,66757,31959,79432,81954,91661,89058,94461,23443,50080,66559,96943,23269,18882,00545,97359,37936,24067,92456,16657,78372,72054,73946,58758,61531,85670,79444,49633,22544,22277,42555,35076,65567,81270,29074,31151,91022,00557,07273,61943,97182,82928,62069,70556,22669,15728,71654,54451,16255,53546,28544,15743,77943,00556,49657,51655,19460,70849,82036,079,05992.66%
nonchim48,00367,86261,53340,66347,38151,71252,42945,40649,29547,63646,64251,06054,99039,73253,56342,67943,89042,47844,25855,21466,15933,75755,28357,09142,62857,58254,71954,20345,68352,18443,28449,70342,93140,64151,81760,54453,87643,44343,64448,37356,08838,64949,24846,76059,48656,04944,91252,23860,70550,31759,65953,54251,63761,70951,78355,12352,37346,91760,07246,14659,78256,81354,76851,30671,97749,80667,10180,802106,79964,38441,44548,76662,48253,54688,85948,00451,68941,15654,68449,07441,53365,23157,45849,75852,47763,48552,18456,98755,34953,22639,58764,44850,13251,58852,00748,41749,07553,34553,42058,01649,66844,23153,80047,37748,04841,46546,76853,06851,29452,90156,20050,32444,07153,61453,70854,43963,97054,27056,89551,66247,71250,98260,74353,46844,16358,39653,95349,14149,56053,21245,63451,46964,04245,57866,77552,10657,63150,77755,47651,31662,69450,20358,81840,53856,37646,87253,76746,07459,12150,91445,06053,86444,31247,13840,11545,34657,49051,91252,41042,92851,41946,91255,92448,49247,39750,95151,96638,69542,95945,56544,15948,33060,85946,34745,65054,36050,64161,91648,83746,80848,28548,11064,44946,24351,05748,28447,76450,29145,73849,82338,06052,48152,88738,33355,31842,34446,19857,52152,19443,10250,92458,07727,78350,75747,44440,40553,61144,94150,14464,82650,02438,17146,56850,00541,03651,57756,28643,41850,76962,39448,29844,18848,38540,26740,81245,73644,69950,12347,96746,84058,65545,64267,31951,38566,11760,31345,40151,65750,75941,81063,03947,12252,70134,88642,31954,00227,56739,55363,24840,27847,53142,94652,02245,01849,21239,38347,05652,64850,80765,63142,02549,80454,24146,28664,98951,52149,87352,76059,81842,23571,45552,49958,59561,19064,98042,82251,45856,62149,79050,08956,60153,67855,82946,87852,00554,42860,19648,89350,93150,13955,47760,14156,78156,92160,68561,39454,24850,25450,16651,31668,01152,18051,91456,13279,16766,65356,96441,86052,60247,95672,94162,18858,43264,75751,95653,62053,90867,33942,41255,51956,89758,30055,68156,77553,62051,68445,88653,51661,95749,52148,39548,75660,05557,70149,02063,33541,75553,44452,31446,26553,73553,63249,04550,41465,16341,21446,26547,12343,32844,15859,70252,61048,07048,84951,49745,55542,09242,94842,58947,84849,85345,92368,37641,56939,39024,08461,91047,61659,76954,16845,51637,71144,59247,97763,65744,54846,50452,69040,70226,58442,28145,51142,56930,59453,43347,94528,11569,36841,92637,09655,52362,83339,83964,25952,99455,72722,81554,54857,64055,61077,83570,60547,54840,39734,86040,81424,51755,10545,60222,16683,33348,95936,53749,74443,76137,38273,08653,88139,84554,61846,57855,29861,59051,77246,73681,32548,19850,85036,76365,09431,98243,88854,89759,23543,47245,51850,49140,65562,75761,42099,84550,41036,90938,93345,85549,40651,74727,36844,03360,45251,70448,43147,18462,35948,66954,74062,38263,81446,41664,31538,13358,66656,69149,55173,75644,42046,4135,12651,84547,83763,19266,71932,28769,44159,32335,63267,90054,55940,96574,71542,63245,91840,86138,60962,30558,31660,89544,51241,26543,53566,61552,90011,37139,25357,09058,83661,03740,77266,16160,04544,90844,10774,91656,00031,31658,09040,37141,07754,61242,23653,46445,48733,73464,11256,99472,86259,55751,97763,72261,29845,63730,81650,73252,58453,01261,27363,43665,09844,57835,16649,71044,11273,78060,11334,79560,27143,08342,43055,26251,26829,99949,73346,39554,42651,74673,67749,17056,43552,90447,78853,08145,81044,64259,04753,91377,04866,65759,21865,38854,53730,69649,04243,32660,47061,86352,39135,16633,78840,05058,78161,38048,04244,21150,50653,44630,55947,10955,41055,08957,04037,28674,02547,92639,79160,64670,75639,26752,72133,73862,10650,93853,51364,26350,32541,31354,74830,16858,10338,12630,93740,26066,39243,90767,19562,12463,21569,34846,97919,16151,91265,37340,65168,95825,64461,86241,49761,74625,12350,14643,98046,04241,65841,75340,66140,45449,30250,25451,17955,99544,42732,264,43682.87%

This table can be downloaded as an Excel table below:

 

5. DADA2 Amplicon Sequence Variants (ASVs). A total of 26929 unique merged and chimera-free ASV sequences were identified, and their corresponding read counts for each sample are available in the "ASV Read Count Table" with rows for the ASV sequences and columns for sample. This read count table can be used for microbial profile comparison among different samples and the sequences provided in the table can be used to taxonomy assignment.

 

The table can be downloaded from this link:

 
 

Sample Meta Information

Download Sample Meta Information
#SampleIDSampleLabelSubject_IDSample TypeTimepointTreatmentGroup
F19514.S00110011001.V1.Saliva10011001SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S00210011002.V1.Saliva10011002SalivaBaselineListerineSaliva.V1.Listerine
F19514.S00310011003.V1.Saliva10011003SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S00410011004.V1.Saliva10011004SalivaBaselineListerineSaliva.V1.Listerine
F19514.S00510011005.V1.Saliva10011005SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S00610011006.V1.Saliva10011006SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S00710011007.V1.Saliva10011007SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S00810011008.V1.Saliva10011008SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S00910011009.V1.Saliva10011009SalivaBaselineListerineSaliva.V1.Listerine
F19514.S01010011010.V1.Saliva10011010SalivaBaselineListerineSaliva.V1.Listerine
F19514.S01110011011.V1.Saliva10011011SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S01210011012.V1.Saliva10011012SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S01310011013.V1.Saliva10011013SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S01410011014.V1.Saliva10011014SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S01510011015.V1.Saliva10011015SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S01610011016.V1.Saliva10011016SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S01710011017.V1.Saliva10011017SalivaBaselineListerineSaliva.V1.Listerine
F19514.S01810011018.V1.Saliva10011018SalivaBaselineListerineSaliva.V1.Listerine
F19514.S01910011019.V1.Saliva10011019SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S02010011020.V1.Saliva10011020SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S02110011021.V1.Saliva10011021SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S02210011022.V1.Saliva10011022SalivaBaselineListerineSaliva.V1.Listerine
F19514.S02310011023.V1.Saliva10011023SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S02410011024.V1.Saliva10011024SalivaBaselineListerineSaliva.V1.Listerine
F19514.S02510011025.V1.Saliva10011025SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S02610011026.V1.Saliva10011026SalivaBaselineListerineSaliva.V1.Listerine
F19514.S02710011027.V1.Saliva10011027SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S02810011028.V1.Saliva10011028SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S02910011029.V1.Saliva10011029SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S03010011030.V1.Saliva10011030SalivaBaselineListerineSaliva.V1.Listerine
F19514.S03110011032.V1.Saliva10011032SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S03210011033.V1.Saliva10011033SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S03310011034.V1.Saliva10011034SalivaBaselineListerineSaliva.V1.Listerine
F19514.S03410011035.V1.Saliva10011035SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S03510011036.V1.Saliva10011036SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S03610011037.V1.Saliva10011037SalivaBaselineListerineSaliva.V1.Listerine
F19514.S03710011038.V1.Saliva10011038SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S03810011039.V1.Saliva10011039SalivaBaselineListerineSaliva.V1.Listerine
F19514.S03910011040.V1.Saliva10011040SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S04010011041.V1.Saliva10011041SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S04110011042.V1.Saliva10011042SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S04210011043.V1.Saliva10011043SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S04310011044.V1.Saliva10011044SalivaBaselineListerineSaliva.V1.Listerine
F19514.S04410011045.V1.Saliva10011045SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S04510011046.V1.Saliva10011046SalivaBaselineListerineSaliva.V1.Listerine
F19514.S04610011047.V1.Saliva10011047SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S04710011048.V1.Saliva10011048SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S04810011049.V1.Saliva10011049SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S04910011050.V1.Saliva10011050SalivaBaselineListerineSaliva.V1.Listerine
F19514.S05010011051.V1.Saliva10011051SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S05110011052.V1.Saliva10011052SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S05210011053.V1.Saliva10011053SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S05310011054.V1.Saliva10011054SalivaBaselineListerineSaliva.V1.Listerine
F19514.S05410011055.V1.Saliva10011055SalivaBaselineListerineSaliva.V1.Listerine
F19514.S05510011056.V1.Saliva10011056SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S05610011057.V1.Saliva10011057SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S05710011058.V1.Saliva10011058SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S05810011059.V1.Saliva10011059SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S05910011060.V1.Saliva10011060SalivaBaselineListerineSaliva.V1.Listerine
F19514.S06010011061.V1.Saliva10011061SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S06110011062.V1.Saliva10011062SalivaBaselineListerineSaliva.V1.Listerine
F19514.S06210011063.V1.Saliva10011063SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S06310011064.V1.Saliva10011064SalivaBaselineListerineSaliva.V1.Listerine
F19514.S06410011065.V1.Saliva10011065SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S06510011066.V1.Saliva10011066SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S06610011067.V1.Saliva10011067SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S06710011068.V1.Saliva10011068SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S06810011069.V1.Saliva10011069SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S06910011070.V1.Saliva10011070SalivaBaselineListerineSaliva.V1.Listerine
F19514.S07010011071.V1.Saliva10011071SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S07110011072.V1.Saliva10011072SalivaBaselineListerineSaliva.V1.Listerine
F19514.S07210011073.V1.Saliva10011073SalivaBaselineListerineSaliva.V1.Listerine
F19514.S07310011074.V1.Saliva10011074SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S07410011075.V1.Saliva10011075SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S07510011076.V1.Saliva10011076SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S07610011077.V1.Saliva10011077SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S07710011078.V1.Saliva10011078SalivaBaselineListerineSaliva.V1.Listerine
F19514.S07810011079.V1.Saliva10011079SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S07910011080.V1.Saliva10011080SalivaBaselineListerineSaliva.V1.Listerine
F19514.S08010011081.V1.Saliva10011081SalivaBaselineListerineSaliva.V1.Listerine
F19514.S08110011082.V1.Saliva10011082SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S08210011083.V1.Saliva10011083SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S08310011084.V1.Saliva10011084SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S08410011085.V1.Saliva10011085SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S08510011086.V1.Saliva10011086SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S08610011087.V1.Saliva10011087SalivaBaselineListerineSaliva.V1.Listerine
F19514.S08710011088.V1.Saliva10011088SalivaBaselineListerineSaliva.V1.Listerine
F19514.S08810011089.V1.Saliva10011089SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S08910011090.V1.Saliva10011090SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S09010011093.V1.Saliva10011093SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S09110011094.V1.Saliva10011094SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S09210011095.V1.Saliva10011095SalivaBaselineListerineSaliva.V1.Listerine
F19514.S09310011096.V1.Saliva10011096SalivaBaselineListerineSaliva.V1.Listerine
F19514.S09410011097.V1.Saliva10011097SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S09510011098.V1.Saliva10011098SalivaBaselineListerineSaliva.V1.Listerine
F19514.S09610011099.V1.Saliva10011099SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S09710011100.V1.Saliva10011100SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S09810011101.V1.Saliva10011101SalivaBaselineListerineSaliva.V1.Listerine
F19514.S09910011102.V1.Saliva10011102SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S10010011103.V1.Saliva10011103SalivaBaselineListerineSaliva.V1.Listerine
F19514.S10110011104.V1.Saliva10011104SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S10210011105.V1.Saliva10011105SalivaBaselineListerineSaliva.V1.Listerine
F19514.S10310011106.V1.Saliva10011106SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S10410011107.V1.Saliva10011107SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S10510011108.V1.Saliva10011108SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S10610011109.V1.Saliva10011109SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S10710011110.V1.Saliva10011110SalivaBaselineListerineSaliva.V1.Listerine
F19514.S10810011111.V1.Saliva10011111SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S10910011112.V1.Saliva10011112SalivaBaselineListerineSaliva.V1.Listerine
F19514.S11010011113.V1.Saliva10011113SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S11110011114.V1.Saliva10011114SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S11210011115.V1.Saliva10011115SalivaBaselineListerineSaliva.V1.Listerine
F19514.S11310011116.V1.Saliva10011116SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S11410011117.V1.Saliva10011117SalivaBaselineListerineSaliva.V1.Listerine
F19514.S11510011118.V1.Saliva10011118SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S11610011119.V1.Saliva10011119SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S11710011120.V1.Saliva10011120SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S11810011121.V1.Saliva10011121SalivaBaselineListerineSaliva.V1.Listerine
F19514.S11910011122.V1.Saliva10011122SalivaBaselineListerineSaliva.V1.Listerine
F19514.S12010011123.V1.Saliva10011123SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S12110011124.V1.Saliva10011124SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S12210011125.V1.Saliva10011125SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S12310011126.V1.Saliva10011126SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S12410011127.V1.Saliva10011127SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S12510011128.V1.Saliva10011128SalivaBaselineListerineSaliva.V1.Listerine
F19514.S12610011129.V1.Saliva10011129SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S12710011130.V1.Saliva10011130SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S12810011131.V1.Saliva10011131SalivaBaselineListerineSaliva.V1.Listerine
F19514.S12910011132.V1.Saliva10011132SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S13010011133.V1.SalivaNANANANANA
F19514.S13110011134.V1.Saliva10011134SalivaBaselineListerineSaliva.V1.Listerine
F19514.S13210011135.V1.Saliva10011135SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S13310011136.V1.Saliva10011136SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S13410011137.V1.Saliva10011137SalivaBaselineListerineSaliva.V1.Listerine
F19514.S13510011138.V1.Saliva10011138SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S13610011139.V1.Saliva10011139SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S13710011140.V1.Saliva10011140SalivaBaselineListerineSaliva.V1.Listerine
F19514.S13810011141.V1.Saliva10011141SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S13910011142.V1.Saliva10011142SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S14010011143.V1.Saliva10011143SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S14110011144.V1.Saliva10011144SalivaBaselineListerineSaliva.V1.Listerine
F19514.S14210011145.V1.Saliva10011145SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S14310011146.V1.Saliva10011146SalivaBaselineListerineSaliva.V1.Listerine
F19514.S14410011147.V1.Saliva10011147SalivaBaselineListerineSaliva.V1.Listerine
F19514.S14510011148.V1.Saliva10011148SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S14610011149.V1.Saliva10011149SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S14710011150.V1.Saliva10011150SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S14810011151.V1.Saliva10011151SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S14910011152.V1.Saliva10011152SalivaBaselineListerineSaliva.V1.Listerine
F19514.S15010011153.V1.Saliva10011153SalivaBaselineListerineSaliva.V1.Listerine
F19514.S15110011154.V1.Saliva10011154SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S15210011155.V1.Saliva10011155SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S15310011156.V1.Saliva10011156SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S15410011157.V1.Saliva10011157SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S15510011158.V1.Saliva10011158SalivaBaselineJolly_RancherSaliva.V1.Jolly_Rancher
F19514.S15610011159.V1.Saliva10011159SalivaBaselineBrush_OnlySaliva.V1.Brush_Only
F19514.S15710011160.V1.Saliva10011160SalivaBaselineListerineSaliva.V1.Listerine
F19514.S15810011161.V1.Saliva10011161SalivaBaselineListerineSaliva.V1.Listerine
F19514.S15910011001.V3.Saliva10011001SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S16010011002.V3.Saliva10011002SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S16110011003.V3.Saliva10011003SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S16210011004.V3.Saliva10011004SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S16310011005.V3.Saliva10011005SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S16410011006.V3.Saliva10011006SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S16510011007.V3.Saliva10011007SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S16610011008.V3.Saliva10011008SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S16710011009.V3.Saliva10011009SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S16810011010.V3.Saliva10011010SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S16910011011.V3.Saliva10011011SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S17010011012.V3.Saliva10011012SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S17110011013.V3.Saliva10011013SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S17210011014.V3.Saliva10011014SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S17310011015.V3.Saliva10011015SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S17410011016.V3.Saliva10011016SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S17510011017.V3.Saliva10011017SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S17610011018.V3.Saliva10011018SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S17710011019.V3.Saliva10011019SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S17810011020.V3.Saliva10011020SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S17910011021.V3.Saliva10011021SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S18010011022.V3.Saliva10011022SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S18110011023.V3.Saliva10011023SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S18210011024.V3.Saliva10011024SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S18310011025.V3.Saliva10011025SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S18410011026.V3.Saliva10011026SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S18510011027.V3.Saliva10011027SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S18610011028.V3.Saliva10011028SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S18710011029.V3.Saliva10011029SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S18810011030.V3.Saliva10011030SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S18910011032.V3.Saliva10011032SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S19010011033.V3.Saliva10011033SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S19110011034.V3.Saliva10011034SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S19210011035.V3.Saliva10011035SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S19310011036.V3.Saliva10011036SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S19410011037.V3.Saliva10011037SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S19510011038.V3.Saliva10011038SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S19610011039.V3.Saliva10011039SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S19710011040.V3.Saliva10011040SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S19810011041.V3.Saliva10011041SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S19910011042.V3.Saliva10011042SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S20010011043.V3.Saliva10011043SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S20110011044.V3.Saliva10011044SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S20210011045.V3.Saliva10011045SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S20310011046.V3.Saliva10011046SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S20410011047.V3.Saliva10011047SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S20510011048.V3.Saliva10011048SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S20610011049.V3.Saliva10011049SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S20710011050.V3.Saliva10011050SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S20810011051.V3.Saliva10011051SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S20910011052.V3.Saliva10011052SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S21010011053.V3.Saliva10011053SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S21110011054.V3.Saliva10011054SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S21210011055.V3.Saliva10011055SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S21310011056.V3.Saliva10011056SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S21410011057.V3.Saliva10011057SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S21510011058.V3.Saliva10011058SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S21610011059.V3.Saliva10011059SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S21710011060.V3.Saliva10011060SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S21810011061.V3.Saliva10011061SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S21910011062.V3.Saliva10011062SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S22010011063.V3.Saliva10011063SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S22110011064.V3.Saliva10011064SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S22210011065.V3.Saliva10011065SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S22310011066.V3.Saliva10011066SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S22410011067.V3.Saliva10011067SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S22510011068.V3.Saliva10011068SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S22610011069.V3.Saliva10011069SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S22710011070.V3.Saliva10011070SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S22810011071.V3.Saliva10011071SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S22910011072.V3.Saliva10011072SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S23010011073.V3.Saliva10011073SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S23110011074.V3.Saliva10011074SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S23210011075.V3.Saliva10011075SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S23310011076.V3.Saliva10011076SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S23410011077.V3.Saliva10011077SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S23510011078.V3.Saliva10011078SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S23610011079.V3.Saliva10011079SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S23710011080.V3.Saliva10011080SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S23810011081.V3.Saliva10011081SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S23910011082.V3.Saliva10011082SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S24010011083.V3.Saliva10011083SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S24110011084.V3.Saliva10011084SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S24210011085.V3.Saliva10011085SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S24310011086.V3.Saliva10011086SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S24410011087.V3.Saliva10011087SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S24510011088.V3.Saliva10011088SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S24610011089.V3.Saliva10011089SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S24710011090.V3.Saliva10011090SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S24810011093.V3.Saliva10011093SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S24910011094.V3.Saliva10011094SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S25010011095.V3.Saliva10011095SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S25110011096.V3.Saliva10011096SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S25210011097.V3.Saliva10011097SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S25310011098.V3.Saliva10011098SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S25410011099.V3.Saliva10011099SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S25510011100.V3.Saliva10011100SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S25610011101.V3.Saliva10011101SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S25710011102.V3.Saliva10011102SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S25810011103.V3.Saliva10011103SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S25910011104.V3.Saliva10011104SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S26010011105.V3.Saliva10011105SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S26110011106.V3.Saliva10011106SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S26210011107.V3.Saliva10011107SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S26310011108.V3.Saliva10011108SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S26410011109.V3.Saliva10011109SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S26510011110.V3.Saliva10011110SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S26610011111.V3.Saliva10011111SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S26710011112.V3.Saliva10011112SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S26810011113.V3.Saliva10011113SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S26910011114.V3.Saliva10011114SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S27010011115.V3.Saliva10011115SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S27110011116.V3.Saliva10011116SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S27210011117.V3.Saliva10011117SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S27310011118.V3.Saliva10011118SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S27410011119.V3.Saliva10011119SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S27510011120.V3.Saliva10011120SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S27610011121.V3.Saliva10011121SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S27710011122.V3.Saliva10011122SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S27810011123.V3.Saliva10011123SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S27910011124.V3.Saliva10011124SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S28010011125.V3.Saliva10011125SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S28110011126.V3.Saliva10011126SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S28210011127.V3.Saliva10011127SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S28310011128.V3.Saliva10011128SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S28410011129.V3.Saliva10011129SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S28510011130.V3.Saliva10011130SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S28610011131.V3.Saliva10011131SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S28710011132.V3.Saliva10011132SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S28810011133.V3.SalivaNANANANANA
F19514.S28910011134.V3.Saliva10011134SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S29010011135.V3.Saliva10011135SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S29110011136.V3.Saliva10011136SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S29210011137.V3.Saliva10011137SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S29310011138.V3.Saliva10011138SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S29410011139.V3.Saliva10011139SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S29510011140.V3.Saliva10011140SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S29610011141.V3.Saliva10011141SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S29710011142.V3.Saliva10011142SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S29810011143.V3.Saliva10011143SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S29910011144.V3.Saliva10011144SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S30010011145.V3.Saliva10011145SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S30110011146.V3.Saliva10011146SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S30210011147.V3.Saliva10011147SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S30310011148.V3.Saliva10011148SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S30410011149.V3.Saliva10011149SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S30510011150.V3.Saliva10011150SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S30610011151.V3.Saliva10011151SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S30710011152.V3.Saliva10011152SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S30810011153.V3.Saliva10011153SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S30910011154.V3.Saliva10011154SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S31010011155.V3.Saliva10011155SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S31110011156.V3.Saliva10011156SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S31210011157.V3.Saliva10011157SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S31310011158.V3.Saliva10011158SalivaDay_28Jolly_RancherSaliva.V3.Jolly_Rancher
F19514.S31410011159.V3.Saliva10011159SalivaDay_28Brush_OnlySaliva.V3.Brush_Only
F19514.S31510011160.V3.Saliva10011160SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S31610011161.V3.Saliva10011161SalivaDay_28ListerineSaliva.V3.Listerine
F19514.S31710011001.V1.Plaque10011001PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S31810011002.V1.Plaque10011002PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S31910011003.V1.Plaque10011003PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S32010011004.V1.Plaque10011004PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S32110011005.V1.Plaque10011005PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S32210011006.V1.Plaque10011006PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S32310011007.V1.Plaque10011007PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S32410011008.V1.Plaque10011008PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S32510011009.V1.Plaque10011009PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S32610011010.V1.Plaque10011010PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S32710011011.V1.Plaque10011011PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S32810011012.V1.Plaque10011012PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S32910011013.V1.Plaque10011013PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S33010011014.V1.Plaque10011014PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S33110011015.V1.Plaque10011015PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S33210011016.V1.Plaque10011016PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S33310011017.V1.Plaque10011017PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S33410011018.V1.Plaque10011018PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S33510011019.V1.Plaque10011019PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S33610011020.V1.Plaque10011020PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S33710011021.V1.Plaque10011021PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S33810011022.V1.Plaque10011022PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S33910011023.V1.Plaque10011023PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S34010011024.V1.Plaque10011024PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S34110011025.V1.Plaque10011025PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S34210011026.V1.Plaque10011026PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S34310011027.V1.Plaque10011027PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S34410011028.V1.Plaque10011028PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S34510011029.V1.Plaque10011029PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S34610011030.V1.Plaque10011030PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S34710011032.V1.Plaque10011032PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S34810011033.V1.Plaque10011033PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S34910011034.V1.Plaque10011034PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S35010011035.V1.Plaque10011035PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S35110011036.V1.Plaque10011036PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S35210011037.V1.Plaque10011037PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S35310011038.V1.Plaque10011038PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S35410011039.V1.Plaque10011039PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S35510011040.V1.Plaque10011040PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S35610011041.V1.Plaque10011041PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S35710011042.V1.Plaque10011042PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S35810011043.V1.Plaque10011043PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S35910011044.V1.Plaque10011044PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S36010011045.V1.Plaque10011045PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S36110011046.V1.Plaque10011046PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S36210011047.V1.Plaque10011047PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S36310011048.V1.Plaque10011048PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S36410011049.V1.Plaque10011049PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S36510011050.V1.Plaque10011050PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S36610011051.V1.Plaque10011051PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S36710011052.V1.Plaque10011052PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S36810011053.V1.Plaque10011053PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S36910011054.V1.Plaque10011054PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S37010011055.V1.Plaque10011055PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S37110011056.V1.Plaque10011056PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S37210011057.V1.Plaque10011057PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S37310011058.V1.Plaque10011058PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S37410011059.V1.Plaque10011059PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S37510011060.V1.Plaque10011060PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S37610011061.V1.Plaque10011061PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S37710011062.V1.Plaque10011062PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S37810011063.V1.Plaque10011063PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S37910011064.V1.Plaque10011064PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S38010011065.V1.Plaque10011065PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S38110011066.V1.Plaque10011066PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S38210011067.V1.Plaque10011067PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S38310011068.V1.Plaque10011068PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S38410011069.V1.Plaque10011069PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S38510011070.V1.Plaque10011070PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S38610011071.V1.Plaque10011071PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S38710011072.V1.Plaque10011072PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S38810011073.V1.Plaque10011073PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S38910011074.V1.Plaque10011074PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S39010011075.V1.Plaque10011075PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S39110011076.V1.Plaque10011076PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S39210011077.V1.Plaque10011077PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S39310011078.V1.Plaque10011078PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S39410011079.V1.Plaque10011079PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S39510011080.V1.Plaque10011080PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S39610011081.V1.Plaque10011081PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S39710011082.V1.Plaque10011082PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S39810011083.V1.Plaque10011083PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S39910011084.V1.Plaque10011084PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S40010011085.V1.Plaque10011085PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S40110011086.V1.Plaque10011086PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S40210011087.V1.Plaque10011087PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S40310011088.V1.Plaque10011088PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S40410011089.V1.Plaque10011089PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S40510011090.V1.Plaque10011090PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S40610011093.V1.Plaque10011093PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S40710011094.V1.Plaque10011094PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S40810011095.V1.Plaque10011095PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S40910011096.V1.Plaque10011096PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S41010011097.V1.Plaque10011097PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S41110011098.V1.Plaque10011098PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S41210011099.V1.Plaque10011099PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S41310011100.V1.Plaque10011100PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S41410011101.V1.Plaque10011101PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S41510011102.V1.Plaque10011102PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S41610011103.V1.Plaque10011103PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S41710011104.V1.Plaque10011104PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S41810011105.V1.Plaque10011105PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S41910011106.V1.Plaque10011106PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S42010011107.V1.Plaque10011107PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S42110011108.V1.Plaque10011108PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S42210011109.V1.Plaque10011109PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S42310011110.V1.Plaque10011110PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S42410011111.V1.Plaque10011111PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S42510011112.V1.Plaque10011112PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S42610011113.V1.Plaque10011113PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S42710011114.V1.Plaque10011114PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S42810011115.V1.Plaque10011115PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S42910011116.V1.Plaque10011116PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S43010011117.V1.Plaque10011117PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S43110011118.V1.Plaque10011118PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S43210011119.V1.Plaque10011119PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S43310011120.V1.Plaque10011120PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S43410011121.V1.Plaque10011121PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S43510011122.V1.Plaque10011122PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S43610011123.V1.Plaque10011123PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S43710011124.V1.Plaque10011124PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S43810011125.V1.Plaque10011125PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S43910011126.V1.Plaque10011126PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S44010011127.V1.Plaque10011127PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S44110011128.V1.Plaque10011128PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S44210011129.V1.Plaque10011129PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S44310011130.V1.Plaque10011130PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S44410011131.V1.Plaque10011131PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S44510011132.V1.Plaque10011132PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S44610011134.V1.Plaque10011134PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S44710011135.V1.Plaque10011135PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S44810011136.V1.Plaque10011136PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S44910011137.V1.Plaque10011137PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S45010011138.V1.Plaque10011138PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S45110011139.V1.Plaque10011139PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S45210011140.V1.Plaque10011140PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S45310011141.V1.Plaque10011141PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S45410011142.V1.Plaque10011142PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S45510011143.V1.Plaque10011143PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S45610011144.V1.Plaque10011144PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S45710011145.V1.Plaque10011145PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S45810011146.V1.Plaque10011146PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S45910011147.V1.Plaque10011147PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S46010011148.V1.Plaque10011148PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S46110011149.V1.Plaque10011149PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S46210011150.V1.Plaque10011150PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S46310011151.V1.Plaque10011151PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S46410011152.V1.Plaque10011152PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S46510011153.V1.Plaque10011153PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S46610011154.V1.Plaque10011154PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S46710011155.V1.Plaque10011155PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S46810011156.V1.Plaque10011156PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S46910011157.V1.Plaque10011157PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S47010011158.V1.Plaque10011158PlaqueBaselineJolly_RancherPlaque.V1.Jolly_Rancher
F19514.S47110011159.V1.Plaque10011159PlaqueBaselineBrush_OnlyPlaque.V1.Brush_Only
F19514.S47210011160.V1.Plaque10011160PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S47310011161.V1.Plaque10011161PlaqueBaselineListerinePlaque.V1.Listerine
F19514.S47410011001.V3.Plaque10011001PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S47510011002.V3.Plaque10011002PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S47610011003.V3.Plaque10011003PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S47710011004.V3.Plaque10011004PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S47810011005.V3.Plaque10011005PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S47910011006.V3.Plaque10011006PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S48010011007.V3.Plaque10011007PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S48110011008.V3.Plaque10011008PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S48210011009.V3.Plaque10011009PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S48310011010.V3.Plaque10011010PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S48410011011.V3.Plaque10011011PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S48510011012.V3.Plaque10011012PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S48610011013.V3.Plaque10011013PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S48710011014.V3.Plaque10011014PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S48810011015.V3.Plaque10011015PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S48910011016.V3.Plaque10011016PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S49010011017.V3.Plaque10011017PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S49110011018.V3.Plaque10011018PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S49210011019.V3.Plaque10011019PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S49310011020.V3.Plaque10011020PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S49410011021.V3.Plaque10011021PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S49510011022.V3.Plaque10011022PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S49610011023.V3.Plaque10011023PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S49710011024.V3.Plaque10011024PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S49810011025.V3.Plaque10011025PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S49910011026.V3.Plaque10011026PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S50010011027.V3.Plaque10011027PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S50110011028.V3.Plaque10011028PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S50210011029.V3.Plaque10011029PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S50310011030.V3.Plaque10011030PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S50410011032.V3.Plaque10011032PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S50510011033.V3.Plaque10011033PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S50610011034.V3.Plaque10011034PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S50710011035.V3.Plaque10011035PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S50810011036.V3.Plaque10011036PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S50910011037.V3.Plaque10011037PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S51010011038.V3.Plaque10011038PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S51110011039.V3.Plaque10011039PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S51210011040.V3.Plaque10011040PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S51310011041.V3.Plaque10011041PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S51410011042.V3.Plaque10011042PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S51510011043.V3.Plaque10011043PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S51610011044.V3.Plaque10011044PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S51710011045.V3.Plaque10011045PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S51810011046.V3.Plaque10011046PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S51910011047.V3.Plaque10011047PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S52010011048.V3.Plaque10011048PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S52110011049.V3.Plaque10011049PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S52210011050.V3.Plaque10011050PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S52310011051.V3.Plaque10011051PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S52410011052.V3.Plaque10011052PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S52510011053.V3.Plaque10011053PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S52610011054.V3.Plaque10011054PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S52710011055.V3.Plaque10011055PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S52810011056.V3.Plaque10011056PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S52910011057.V3.Plaque10011057PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S53010011058.V3.Plaque10011058PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S53110011059.V3.Plaque10011059PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S53210011060.V3.Plaque10011060PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S53310011061.V3.Plaque10011061PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S53410011062.V3.Plaque10011062PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S53510011063.V3.Plaque10011063PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S53610011064.V3.Plaque10011064PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S53710011065.V3.Plaque10011065PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S53810011066.V3.Plaque10011066PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S53910011067.V3.Plaque10011067PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S54010011068.V3.Plaque10011068PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S54110011069.V3.Plaque10011069PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S54210011070.V3.Plaque10011070PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S54310011071.V3.Plaque10011071PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S54410011072.V3.Plaque10011072PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S54510011073.V3.Plaque10011073PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S54610011074.V3.Plaque10011074PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S54710011075.V3.Plaque10011075PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S54810011076.V3.Plaque10011076PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S54910011077.V3.Plaque10011077PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S55010011078.V3.Plaque10011078PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S55110011079.V3.Plaque10011079PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S55210011080.V3.Plaque10011080PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S55310011081.V3.Plaque10011081PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S55410011082.V3.Plaque10011082PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S55510011083.V3.Plaque10011083PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S55610011084.V3.Plaque10011084PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S55710011085.V3.Plaque10011085PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S55810011086.V3.Plaque10011086PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S55910011087.V3.Plaque10011087PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S56010011088.V3.Plaque10011088PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S56110011089.V3.Plaque10011089PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S56210011090.V3.Plaque10011090PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S56310011093.V3.Plaque10011093PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S56410011094.V3.Plaque10011094PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S56510011095.V3.Plaque10011095PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S56610011096.V3.Plaque10011096PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S56710011097.V3.Plaque10011097PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S56810011098.V3.Plaque10011098PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S56910011099.V3.Plaque10011099PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S57010011100.V3.Plaque10011100PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S57110011101.V3.Plaque10011101PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S57210011102.V3.Plaque10011102PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S57310011103.V3.Plaque10011103PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S57410011104.V3.Plaque10011104PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S57510011105.V3.Plaque10011105PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S57610011106.V3.Plaque10011106PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S57710011107.V3.Plaque10011107PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S57810011108.V3.Plaque10011108PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S57910011109.V3.Plaque10011109PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S58010011110.V3.Plaque10011110PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S58110011111.V3.Plaque10011111PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S58210011112.V3.Plaque10011112PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S58310011113.V3.Plaque10011113PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S58410011114.V3.Plaque10011114PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S58510011115.V3.Plaque10011115PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S58610011116.V3.Plaque10011116PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S58710011117.V3.Plaque10011117PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S58810011118.V3.Plaque10011118PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S58910011119.V3.Plaque10011119PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S59010011120.V3.Plaque10011120PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S59110011121.V3.Plaque10011121PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S59210011122.V3.Plaque10011122PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S59310011123.V3.Plaque10011123PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S59410011124.V3.Plaque10011124PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S59510011125.V3.Plaque10011125PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S59610011126.V3.Plaque10011126PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S59710011127.V3.Plaque10011127PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S59810011128.V3.Plaque10011128PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S59910011129.V3.Plaque10011129PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S60010011130.V3.Plaque10011130PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S60110011131.V3.Plaque10011131PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S60210011132.V3.Plaque10011132PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S60310011134.V3.Plaque10011134PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S60410011135.V3.Plaque10011135PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S60510011136.V3.Plaque10011136PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S60610011137.V3.Plaque10011137PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S60710011138.V3.Plaque10011138PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S60810011139.V3.Plaque10011139PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S60910011140.V3.Plaque10011140PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S61010011141.V3.Plaque10011141PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S61110011142.V3.Plaque10011142PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S61210011143.V3.Plaque10011143PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S61310011144.V3.Plaque10011144PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S61410011145.V3.Plaque10011145PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S61510011146.V3.Plaque10011146PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S61610011147.V3.Plaque10011147PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S61710011148.V3.Plaque10011148PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S61810011149.V3.Plaque10011149PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S61910011150.V3.Plaque10011150PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S62010011151.V3.Plaque10011151PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S62110011152.V3.Plaque10011152PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S62210011153.V3.Plaque10011153PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S62310011154.V3.Plaque10011154PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S62410011155.V3.Plaque10011155PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S62510011156.V3.Plaque10011156PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S62610011157.V3.Plaque10011157PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S62710011158.V3.Plaque10011158PlaqueDay_28Jolly_RancherPlaque.V3.Jolly_Rancher
F19514.S62810011159.V3.Plaque10011159PlaqueDay_28Brush_OnlyPlaque.V3.Brush_Only
F19514.S62910011160.V3.Plaque10011160PlaqueDay_28ListerinePlaque.V3.Listerine
F19514.S63010011161.V3.Plaque10011161PlaqueDay_28ListerinePlaque.V3.Listerine
 
 

ASV Read Counts by Samples

#Sample IDRead Count
F19514.S4685,126
F19514.S49311,371
F19514.S60919,161
F19514.S41022,166
F19514.S39722,815
F19514.S36624,084
F19514.S40724,517
F19514.S61825,123
F19514.S61425,644
F19514.S38026,584
F19514.S44827,368
F19514.S24727,567
F19514.S20327,783
F19514.S38728,115
F19514.S54129,999
F19514.S59730,168
F19514.S57630,559
F19514.S38430,594
F19514.S56130,696
F19514.S52230,816
F19514.S60030,937
F19514.S50531,316
F19514.S43131,982
F19514.S47332,287
F19514.S51333,734
F19514.S58933,738
F19514.S02233,757
F19514.S56833,788
F19514.S53534,795
F19514.S40534,860
F19514.S24434,886
F19514.S53035,166
F19514.S56735,166
F19514.S47635,632
F19514.S41336,537
F19514.S42936,763
F19514.S44336,909
F19514.S39037,096
F19514.S58137,286
F19514.S41637,382
F19514.S37237,711
F19514.S19138,060
F19514.S59938,126
F19514.S46138,133
F19514.S21238,171
F19514.S19438,333
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F19514.S16838,695
F19514.S44438,933
F19514.S49439,253
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F19514.S24839,553
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F19514.S58439,791
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F19514.S41939,845
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F19514.S15540,115
F19514.S60140,260
F19514.S22440,267
F19514.S25040,278
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F19514.S62540,454
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F19514.S43840,655
F19514.S62440,661
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F19514.S48340,861
F19514.S47940,965
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F19514.S62341,753
F19514.S33741,755
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F19514.S30841,860
F19514.S38941,926
F19514.S26142,025
F19514.S35742,092
F19514.S27042,235
F19514.S51042,236
F19514.S38142,281
F19514.S24542,319
F19514.S19642,344
F19514.S31942,412
F19514.S53842,430
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F19514.S38342,569
F19514.S35942,589
F19514.S02542,628
F19514.S48142,632
F19514.S01642,679
F19514.S27642,822
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F19514.S03342,931
F19514.S25242,946
F19514.S35842,948
F19514.S16942,959
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F19514.S43243,888
F19514.S01743,890
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F19514.S10244,231
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F19514.S46644,420
F19514.S63044,427
F19514.S48844,512
F19514.S37644,548
F19514.S52944,578
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F19514.S50144,908
F19514.S04744,912
F19514.S20844,941
F19514.S25445,018
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F19514.S23745,401
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F19514.S38245,511
F19514.S37145,516
F19514.S43645,518
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F19514.S13445,578
F19514.S40945,602
F19514.S13145,634
F19514.S52145,637
F19514.S23245,642
F19514.S17545,650
F19514.S02945,683
F19514.S22645,736
F19514.S18945,738
F19514.S55245,810
F19514.S44545,855
F19514.S32745,886
F19514.S48245,918
F19514.S36245,923
F19514.S62146,042
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F19514.S18446,243
F19514.S34046,265
F19514.S34746,265
F19514.S26446,286
F19514.S17446,347
F19514.S54346,395
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F19514.S45946,416
F19514.S37746,504
F19514.S21346,568
F19514.S42146,578
F19514.S01146,642
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F19514.S10746,768
F19514.S18046,808
F19514.S23046,840
F19514.S14646,872
F19514.S28446,878
F19514.S16246,912
F19514.S05846,917
F19514.S60846,979
F19514.S25747,056
F19514.S57747,109
F19514.S24247,122
F19514.S34847,123
F19514.S15447,138
F19514.S45347,184
F19514.S10447,377
F19514.S00547,381
F19514.S16547,397
F19514.S20547,444
F19514.S25147,531
F19514.S40347,548
F19514.S36847,616
F19514.S01047,636
F19514.S12147,712
F19514.S18747,764
F19514.S55047,788
F19514.S47047,837
F19514.S36047,848
F19514.S58347,926
F19514.S38647,945
F19514.S31047,956
F19514.S22947,967
F19514.S37447,977
F19514.S00148,003
F19514.S07648,004
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F19514.S35348,070
F19514.S18248,110
F19514.S42748,198
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F19514.S18148,285
F19514.S22148,298
F19514.S17248,330
F19514.S04048,373
F19514.S22348,385
F19514.S33148,395
F19514.S09648,417
F19514.S45248,431
F19514.S16448,492
F19514.S45548,669
F19514.S33248,756
F19514.S07248,766
F19514.S17948,837
F19514.S35448,849
F19514.S28848,893
F19514.S41248,959
F19514.S33549,020
F19514.S56249,042
F19514.S34349,045
F19514.S08049,074
F19514.S09749,075
F19514.S12849,141
F19514.S54749,170
F19514.S25549,212
F19514.S04349,248
F19514.S00949,295
F19514.S62649,302
F19514.S44649,406
F19514.S33049,521
F19514.S46449,551
F19514.S12949,560
F19514.S10149,668
F19514.S03249,703
F19514.S53149,710
F19514.S54249,733
F19514.S41449,744
F19514.S08449,758
F19514.S27949,790
F19514.S26249,804
F19514.S06649,806
F19514.S19049,823
F19514.S36149,853
F19514.S26749,873
F19514.S21450,005
F19514.S21150,024
F19514.S28050,089
F19514.S22850,123
F19514.S09350,132
F19514.S29050,139
F19514.S20950,144
F19514.S61950,146
F19514.S29950,166
F19514.S14250,203
F19514.S62750,254
F19514.S29850,254
F19514.S18850,291
F19514.S05050,317
F19514.S11250,324
F19514.S59450,325
F19514.S44250,410
F19514.S34450,414
F19514.S43750,491
F19514.S57450,506
F19514.S17750,641
F19514.S52350,732
F19514.S20450,757
F19514.S23950,759
F19514.S21950,769
F19514.S13850,777
F19514.S25950,807
F19514.S42850,850
F19514.S15050,914
F19514.S20150,924
F19514.S28950,931
F19514.S59150,938
F19514.S16650,951
F19514.S12250,982
F19514.S18551,057
F19514.S01251,060
F19514.S62851,179
F19514.S54051,268
F19514.S10951,294
F19514.S06451,306
F19514.S14051,316
F19514.S30051,316
F19514.S23451,385
F19514.S16151,419
F19514.S27751,458
F19514.S13251,469
F19514.S35551,497
F19514.S26651,521
F19514.S21651,577
F19514.S09451,588
F19514.S05351,637
F19514.S23851,657
F19514.S12051,662
F19514.S32651,684
F19514.S07751,689
F19514.S45151,704
F19514.S00651,712
F19514.S54551,746
F19514.S44751,747
F19514.S42451,772
F19514.S05551,783
F19514.S03551,817
F19514.S46951,845
F19514.S15851,912
F19514.S61051,912
F19514.S30351,914
F19514.S31551,956
F19514.S16751,966
F19514.S51851,977
F19514.S28552,005
F19514.S09552,007
F19514.S25352,022
F19514.S13652,106
F19514.S30252,180
F19514.S08752,184
F19514.S03052,184
F19514.S19952,194
F19514.S04852,238
F19514.S33952,314
F19514.S05752,373
F19514.S56652,391
F19514.S15952,410
F19514.S00752,429
F19514.S08552,477
F19514.S19252,481
F19514.S27252,499
F19514.S52452,584
F19514.S30952,602
F19514.S35252,610
F19514.S25852,648
F19514.S37852,690
F19514.S24352,701
F19514.S58852,721
F19514.S26852,760
F19514.S19352,887
F19514.S49252,900
F19514.S11052,901
F19514.S54952,904
F19514.S39552,994
F19514.S52553,012
F19514.S10853,068
F19514.S55153,081
F19514.S13053,212
F19514.S09053,226
F19514.S09853,345
F19514.S09953,420
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F19514.S57553,446
F19514.S51153,464
F19514.S12453,468
F19514.S59253,513
F19514.S32853,516
F19514.S05253,542
F19514.S07453,546
F19514.S01553,563
F19514.S20753,611
F19514.S11453,614
F19514.S31653,620
F19514.S32553,620
F19514.S34253,632
F19514.S28253,678
F19514.S11553,708
F19514.S34153,735
F19514.S14753,767
F19514.S10353,800
F19514.S15253,864
F19514.S03753,876
F19514.S41853,881
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F19514.S55553,913
F19514.S12753,953
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F19514.S56054,537
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F19514.S42255,298
F19514.S19555,318
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F19514.S29155,477
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F19514.S39155,523
F19514.S40055,610
F19514.S32355,681
F19514.S39655,727
F19514.S28355,829
F19514.S16355,924
F19514.S62955,995
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F19514.S27856,621
F19514.S46356,691
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F19514.S30756,964
F19514.S08856,987
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F19514.S06159,782
F19514.S26959,818
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F19514.S53660,271
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F19514.S45060,452
F19514.S56460,470
F19514.S03660,544
F19514.S58560,646
F19514.S29560,685
F19514.S04960,705
F19514.S12360,743
F19514.S17360,859
F19514.S48760,895
F19514.S49761,037
F19514.S27461,190
F19514.S52661,273
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F19514.S57161,380
F19514.S29661,394
F19514.S44061,420
F19514.S00361,533
F19514.S42361,590
F19514.S05461,709
F19514.S61761,746
F19514.S61561,862
F19514.S56561,863
F19514.S36761,910
F19514.S17861,916
F19514.S32961,957
F19514.S59062,106
F19514.S60562,124
F19514.S31262,188
F19514.S48562,305
F19514.S45462,359
F19514.S45762,382
F19514.S22062,394
F19514.S07362,482
F19514.S14162,694
F19514.S43962,757
F19514.S39262,833
F19514.S24163,039
F19514.S47163,192
F19514.S60663,215
F19514.S24963,248
F19514.S33663,335
F19514.S52763,436
F19514.S08663,485
F19514.S37563,657
F19514.S51963,722
F19514.S45863,814
F19514.S11763,970
F19514.S13364,042
F19514.S51464,112
F19514.S39464,259
F19514.S59364,263
F19514.S46064,315
F19514.S07064,384
F19514.S09264,448
F19514.S18364,449
F19514.S31464,757
F19514.S21064,826
F19514.S27564,980
F19514.S26564,989
F19514.S43065,094
F19514.S52865,098
F19514.S34565,163
F19514.S08265,231
F19514.S61165,373
F19514.S55965,388
F19514.S26065,631
F19514.S23566,117
F19514.S02166,159
F19514.S49966,161
F19514.S60266,392
F19514.S49166,615
F19514.S30666,653
F19514.S55766,657
F19514.S47266,719
F19514.S13566,775
F19514.S06767,101
F19514.S60467,195
F19514.S23367,319
F19514.S31867,339
F19514.S00267,862
F19514.S47767,900
F19514.S30168,011
F19514.S36368,376
F19514.S61368,958
F19514.S60769,348
F19514.S38869,368
F19514.S47469,441
F19514.S40270,605
F19514.S58670,756
F19514.S27171,455
F19514.S06571,977
F19514.S51672,862
F19514.S31172,941
F19514.S41773,086
F19514.S54673,677
F19514.S46573,756
F19514.S53373,780
F19514.S58274,025
F19514.S48074,715
F19514.S50374,916
F19514.S55677,048
F19514.S40177,835
F19514.S30579,167
F19514.S06880,802
F19514.S42681,325
F19514.S41183,333
F19514.S07588,859
F19514.S44199,845
F19514.S069106,799
 
 
 

VII. Analysis - Read Taxonomy Assignment

Read Taxonomy Assignment - Methods

 

The close-reference taxonomy assignment of the ASV sequences using BLASTN is based on the algorithm published by Al-Hebshi et. al. (2015)[2].

The species-level, open-reference 16S rRNA NGS reads taxonomy assignment pipeline

Version 20210310a
 
 

1. Raw sequences reads in FASTA format were BLASTN-searched against a combined set of 16S rRNA reference sequences - the FOMC 16S rRNA Reference Sequences version 20221029 (https://microbiome.forsyth.org/ftp/refseq/). This set consists of the HOMD (version 15.22 http://www.homd.org/index.php?name=seqDownload&file&type=R ), Mouse Oral Microbiome Database (MOMD version 5.1 https://momd.org/ftp/16S_rRNA_refseq/MOMD_16S_rRNA_RefSeq/V5.1/), and the NCBI 16S rRNA reference sequence set (https://ftp.ncbi.nlm.nih.gov/blast/db/16S_ribosomal_RNA.tar.gz). These sequences were screened and combined to remove short sequences (<1000nt), chimera, duplicated and sub-sequences, as well as sequences with poor taxonomy annotation (e.g., without species information). This process resulted in 1,015 full-length 16S rRNA sequences from HOMD V15.22, 356 from MOMD V5.1, and 22,126 from NCBI, a total of 23,497 sequences. Altogether these sequence represent a total of 17,035 oral and non-oral microbial species.

The NCBI BLASTN version 2.7.1+ (Zhang et al, 2000) [3] was used with the default parameters. Reads with ≥ 98% sequence identity to the matched reference and ≥ 90% alignment length (i.e., ≥ 90% of the read length that was aligned to the reference and was used to calculate the sequence percent identity) were classified based on the taxonomy of the reference sequence with highest sequence identity. If a read matched with reference sequences representing more than one species with equal percent identity and alignment length, it was subject to chimera checking with USEARCH program version v8.1.1861 (Edgar 2010). Non-chimeric reads with multi-species best hits were considered valid and were assigned with a unique species notation (e.g., spp) denoting unresolvable multiple species.

2. Unassigned reads (i.e., reads with < 98% identity or < 90% alignment length) were pooled together and reads < 200 bases were removed. The remaining reads were subject to the de novo operational taxonomy unit (OTU) calling and chimera checking using the USEARCH program version v8.1.1861 (Edgar 2010)[4]. The de novo OTU calling and chimera checking was done using 98% as the sequence identity cutoff, i.e., the species-level OTU. The output of this step produced species-level de novo clustered OTUs with 98% identity. Representative reads from each of the OTUs/species were then BLASTN-searched against the same reference sequence set again to determine the closest species for these potential novel species. These potential novel species were pooled together with the reads that were signed to specie-level in the previous step, for down-stream analyses.

Reference:

  1. Al-Hebshi NN, Nasher AT, Idris AM, Chen T. Robust species taxonomy assignment algorithm for 16S rRNA NGS reads: application to oral carcinoma samples. J Oral Microbiol. 2015 Sep 29;7:28934. doi: 10.3402/jom.v7.28934. PMID: 26426306; PMCID: PMC4590409.
  2. Zhang Z, Schwartz S, Wagner L, Miller W. A greedy algorithm for aligning DNA sequences. J Comput Biol. 2000 Feb-Apr;7(1-2):203-14. doi: 10.1089/10665270050081478. PMID: 10890397.
  3. Edgar RC. Search and clustering orders of magnitude faster than BLAST. Bioinformatics. 2010 Oct 1;26(19):2460-1. doi: 10.1093/bioinformatics/btq461. Epub 2010 Aug 12. PubMed PMID: 20709691.

    4. 3. Designations used in the taxonomy:

    	1) Taxonomy levels are indicated by these prefixes:
	
	   k__: domain/kingdom
	   p__: phylum
	   c__: class
	   o__: order
	   f__: family
	   g__: genus  
	   s__: species
	
	   Example: 
	
	   k__Bacteria;p__Firmicutes;c__Clostridia;o__Clostridiales;f__Lachnospiraceae;g__Blautia;s__faecis
		
	2) Unique level identified – known species:
	   
	   k__Bacteria;p__Firmicutes;c__Clostridia;o__Clostridiales;f__Lachnospiraceae;g__Roseburia;s__hominis
	
	   The above example shows some reads match to a single species (all levels are unique)
	
	3) Non-unique level identified – known species:

	   k__Bacteria;p__Firmicutes;c__Clostridia;o__Clostridiales;f__Lachnospiraceae;g__Roseburia;s__multispecies_spp123_3
	   
	   The above example “s__multispecies_spp123_3” indicates certain reads equally match to 3 species of the 
	   genus Roseburia; the “spp123” is a temporally assigned species ID.
	
	   k__Bacteria;p__Firmicutes;c__Clostridia;o__Clostridiales;f__Lachnospiraceae;g__multigenus;s__multispecies_spp234_5
	   
	   The above example indicates certain reads match equally to 5 different species, which belong to multiple genera.; 
	   the “spp234” is a temporally assigned species ID.
	
	4) Unique level identified – unknown species, potential novel species:
	   
	   k__Bacteria;p__Firmicutes;c__Clostridia;o__Clostridiales;f__Lachnospiraceae;g__Roseburia;s__ hominis_nov_97%
	   
	   The above example indicates that some reads have no match to any of the reference sequences with 
	   sequence identity ≥ 98% and percent coverage (alignment length)  ≥ 98% as well. However this groups 
	   of reads (actually the representative read from a de novo  OTU) has 96% percent identity to 
	   Roseburia hominis, thus this is a potential novel species, closest to Roseburia hominis. 
	   (But they are not the same species).
	
	5) Multiple level identified – unknown species, potential novel species:
	   k__Bacteria;p__Firmicutes;c__Clostridia;o__Clostridiales;f__Lachnospiraceae;g__Roseburia;s__ multispecies_sppn123_3_nov_96%
	
	   The above example indicates that some reads have no match to any of the reference sequences 
	   with sequence identity ≥ 98% and percent coverage (alignment length)  ≥ 98% as well. 
	   However this groups of reads (actually the representative read from a de novo  OTU) 
	   has 96% percent identity equally to 3 species in Roseburia. Thus this is no single 
	   closest species, instead this group of reads match equally to multiple species at 96%. 
	   Since they have passed chimera check so they represent a novel species. “sppn123” is a 
	   temporary ID for this potential novel species.

 
4. The taxonomy assignment algorithm is illustrated in this flow char below:
 
 
 
 

Read Taxonomy Assignment - Result Summary *

CodeCategoryMPC=0% (>=1 read)MPC=0.01%(>=3216 reads)
ATotal reads32,264,43632,264,436
BTotal assigned reads32,163,69832,163,698
CAssigned reads in species with read count < MPC0197,641
DAssigned reads in samples with read count < 50000
ETotal samples630630
FSamples with reads >= 500630630
GSamples with reads < 50000
HTotal assigned reads used for analysis (B-C-D)32,163,69831,966,057
IReads assigned to single species30,069,74329,969,483
JReads assigned to multiple species1,157,9041,130,904
KReads assigned to novel species936,051865,670
LTotal number of species1,236326
MNumber of single species520263
NNumber of multi-species7616
ONumber of novel species64047
PTotal unassigned reads100,738100,738
QChimeric reads426426
RReads without BLASTN hits6,7316,731
SOthers: short, low quality, singletons, etc.93,58193,581
A=B+P=C+D+H+Q+R+S
E=F+G
B=C+D+H
H=I+J+K
L=M+N+O
P=Q+R+S
* MPC = Minimal percent (of all assigned reads) read count per species, species with read count < MPC were removed.
* Samples with reads < 500 were removed from downstream analyses.
* The assignment result from MPC=0.1% was used in the downstream analyses.
 
 
 

Read Taxonomy Assignment - ASV Species-Level Read Counts Table

This table shows the read counts for each sample (columns) and each species identified based on the ASV sequences. The downstream analyses were based on this table.
SPIDTaxonomyF19514.S001F19514.S002F19514.S003F19514.S004F19514.S005F19514.S006F19514.S007F19514.S008F19514.S009F19514.S010F19514.S011F19514.S012F19514.S013F19514.S014F19514.S015F19514.S016F19514.S017F19514.S018F19514.S019F19514.S020F19514.S021F19514.S022F19514.S023F19514.S024F19514.S025F19514.S026F19514.S027F19514.S028F19514.S029F19514.S030F19514.S031F19514.S032F19514.S033F19514.S034F19514.S035F19514.S036F19514.S037F19514.S038F19514.S039F19514.S040F19514.S041F19514.S042F19514.S043F19514.S044F19514.S045F19514.S046F19514.S047F19514.S048F19514.S049F19514.S050F19514.S051F19514.S052F19514.S053F19514.S054F19514.S055F19514.S056F19514.S057F19514.S058F19514.S059F19514.S060F19514.S061F19514.S062F19514.S063F19514.S064F19514.S065F19514.S066F19514.S067F19514.S068F19514.S069F19514.S070F19514.S071F19514.S072F19514.S073F19514.S074F19514.S075F19514.S076F19514.S077F19514.S078F19514.S079F19514.S080F19514.S081F19514.S082F19514.S083F19514.S084F19514.S085F19514.S086F19514.S087F19514.S088F19514.S089F19514.S090F19514.S091F19514.S092F19514.S093F19514.S094F19514.S095F19514.S096F19514.S097F19514.S098F19514.S099F19514.S100F19514.S101F19514.S102F19514.S103F19514.S104F19514.S105F19514.S106F19514.S107F19514.S108F19514.S109F19514.S110F19514.S111F19514.S112F19514.S113F19514.S114F19514.S115F19514.S116F19514.S117F19514.S118F19514.S119F19514.S120F19514.S121F19514.S122F19514.S123F19514.S124F19514.S125F19514.S126F19514.S127F19514.S128F19514.S129F19514.S130F19514.S131F19514.S132F19514.S133F19514.S134F19514.S135F19514.S136F19514.S137F19514.S138F19514.S139F19514.S140F19514.S141F19514.S142F19514.S143F19514.S144F19514.S145F19514.S146F19514.S147F19514.S148F19514.S149F19514.S150F19514.S151F19514.S152F19514.S153F19514.S154F19514.S155F19514.S156F19514.S157F19514.S158F19514.S159F19514.S160F19514.S161F19514.S162F19514.S163F19514.S164F19514.S165F19514.S166F19514.S167F19514.S168F19514.S169F19514.S170F19514.S171F19514.S172F19514.S173F19514.S174F19514.S175F19514.S176F19514.S177F19514.S178F19514.S179F19514.S180F19514.S181F19514.S182F19514.S183F19514.S184F19514.S185F19514.S186F19514.S187F19514.S188F19514.S189F19514.S190F19514.S191F19514.S192F19514.S193F19514.S194F19514.S195F19514.S196F19514.S197F19514.S198F19514.S199F19514.S200F19514.S201F19514.S202F19514.S203F19514.S204F19514.S205F19514.S206F19514.S207F19514.S208F19514.S209F19514.S210F19514.S211F19514.S212F19514.S213F19514.S214F19514.S215F19514.S216F19514.S217F19514.S218F19514.S219F19514.S220F19514.S221F19514.S222F19514.S223F19514.S224F19514.S225F19514.S226F19514.S227F19514.S228F19514.S229F19514.S230F19514.S231F19514.S232F19514.S233F19514.S234F19514.S235F19514.S236F19514.S237F19514.S238F19514.S239F19514.S240F19514.S241F19514.S242F19514.S243F19514.S244F19514.S245F19514.S246F19514.S247F19514.S248F19514.S249F19514.S250F19514.S251F19514.S252F19514.S253F19514.S254F19514.S255F19514.S256F19514.S257F19514.S258F19514.S259F19514.S260F19514.S261F19514.S262F19514.S263F19514.S264F19514.S265F19514.S266F19514.S267F19514.S268F19514.S269F19514.S270F19514.S271F19514.S272F19514.S273F19514.S274F19514.S275F19514.S276F19514.S277F19514.S278F19514.S279F19514.S280F19514.S281F19514.S282F19514.S283F19514.S284F19514.S285F19514.S286F19514.S287F19514.S288F19514.S289F19514.S290F19514.S291F19514.S292F19514.S293F19514.S294F19514.S295F19514.S296F19514.S297F19514.S298F19514.S299F19514.S300F19514.S301F19514.S302F19514.S303F19514.S304F19514.S305F19514.S306F19514.S307F19514.S308F19514.S309F19514.S310F19514.S311F19514.S312F19514.S313F19514.S314F19514.S315F19514.S316F19514.S317F19514.S318F19514.S319F19514.S320F19514.S321F19514.S322F19514.S323F19514.S324F19514.S325F19514.S326F19514.S327F19514.S328F19514.S329F19514.S330F19514.S331F19514.S332F19514.S333F19514.S334F19514.S335F19514.S336F19514.S337F19514.S338F19514.S339F19514.S340F19514.S341F19514.S342F19514.S343F19514.S344F19514.S345F19514.S346F19514.S347F19514.S348F19514.S349F19514.S350F19514.S351F19514.S352F19514.S353F19514.S354F19514.S355F19514.S356F19514.S357F19514.S358F19514.S359F19514.S360F19514.S361F19514.S362F19514.S363F19514.S364F19514.S365F19514.S366F19514.S367F19514.S368F19514.S369F19514.S370F19514.S371F19514.S372F19514.S373F19514.S374F19514.S375F19514.S376F19514.S377F19514.S378F19514.S379F19514.S380F19514.S381F19514.S382F19514.S383F19514.S384F19514.S385F19514.S386F19514.S387F19514.S388F19514.S389F19514.S390F19514.S391F19514.S392F19514.S393F19514.S394F19514.S395F19514.S396F19514.S397F19514.S398F19514.S399F19514.S400F19514.S401F19514.S402F19514.S403F19514.S404F19514.S405F19514.S406F19514.S407F19514.S408F19514.S409F19514.S410F19514.S411F19514.S412F19514.S413F19514.S414F19514.S415F19514.S416F19514.S417F19514.S418F19514.S419F19514.S420F19514.S421F19514.S422F19514.S423F19514.S424F19514.S425F19514.S426F19514.S427F19514.S428F19514.S429F19514.S430F19514.S431F19514.S432F19514.S433F19514.S434F19514.S435F19514.S436F19514.S437F19514.S438F19514.S439F19514.S440F19514.S441F19514.S442F19514.S443F19514.S444F19514.S445F19514.S446F19514.S447F19514.S448F19514.S449F19514.S450F19514.S451F19514.S452F19514.S453F19514.S454F19514.S455F19514.S456F19514.S457F19514.S458F19514.S459F19514.S460F19514.S461F19514.S462F19514.S463F19514.S464F19514.S465F19514.S466F19514.S467F19514.S468F19514.S469F19514.S470F19514.S471F19514.S472F19514.S473F19514.S474F19514.S475F19514.S476F19514.S477F19514.S478F19514.S479F19514.S480F19514.S481F19514.S482F19514.S483F19514.S484F19514.S485F19514.S486F19514.S487F19514.S488F19514.S489F19514.S490F19514.S491F19514.S492F19514.S493F19514.S494F19514.S495F19514.S496F19514.S497F19514.S498F19514.S499F19514.S500F19514.S501F19514.S502F19514.S503F19514.S504F19514.S505F19514.S506F19514.S507F19514.S508F19514.S509F19514.S510F19514.S511F19514.S512F19514.S513F19514.S514F19514.S515F19514.S516F19514.S517F19514.S518F19514.S519F19514.S520F19514.S521F19514.S522F19514.S523F19514.S524F19514.S525F19514.S526F19514.S527F19514.S528F19514.S529F19514.S530F19514.S531F19514.S532F19514.S533F19514.S534F19514.S535F19514.S536F19514.S537F19514.S538F19514.S539F19514.S540F19514.S541F19514.S542F19514.S543F19514.S544F19514.S545F19514.S546F19514.S547F19514.S548F19514.S549F19514.S550F19514.S551F19514.S552F19514.S553F19514.S554F19514.S555F19514.S556F19514.S557F19514.S558F19514.S559F19514.S560F19514.S561F19514.S562F19514.S563F19514.S564F19514.S565F19514.S566F19514.S567F19514.S568F19514.S569F19514.S570F19514.S571F19514.S572F19514.S573F19514.S574F19514.S575F19514.S576F19514.S577F19514.S578F19514.S579F19514.S580F19514.S581F19514.S582F19514.S583F19514.S584F19514.S585F19514.S586F19514.S587F19514.S588F19514.S589F19514.S590F19514.S591F19514.S592F19514.S593F19514.S594F19514.S595F19514.S596F19514.S597F19514.S598F19514.S599F19514.S600F19514.S601F19514.S602F19514.S603F19514.S604F19514.S605F19514.S606F19514.S607F19514.S608F19514.S609F19514.S610F19514.S611F19514.S612F19514.S613F19514.S614F19514.S615F19514.S616F19514.S617F19514.S618F19514.S619F19514.S620F19514.S621F19514.S622F19514.S623F19514.S624F19514.S625F19514.S626F19514.S627F19514.S628F19514.S629F19514.S630
SP1Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;jejuni001406030739036270013134451298982143763671793547749015100350005751638283120811420121228106126009792088068177511609030617510202044067067259708119778045850100009600227012329050041837512896385826623673630031315472890243704270000204462915220443238817000079115001761303802371150014801072010721506800140172000080044001018970884003803290921481800593026441829532001461703136975081502528794842800316033000330412439769582212045828848290053027908716680406965013401920120102166279491124569301286220000309004212641630232300424880806468157145981550035556513653214251308840000148516547013451965203690001762741018832265418881830031130371422209462364002258710000000120026363000435002444445405003200000000000000000430010000000000000000000000000000880000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000076000000000000000000000000000029000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000270
SP10Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Schaalia;odontolytica322508764533259515152821494890102626623466120917551916937267640658371052587362190218914564952772393267204644651116219602371530150065792710121113235211629515225846771136767519971723201077205801504260026210221569383645273516088301783664568426106477314950880101761515051435464256410778652816231251610843585863400674840112145723044245542419321489139916539766808584695951706274056293201419456523911211440187879657348624181225418263718244557810178492089543252378753631131337814346291032380331435118215521129918702616933279579666601466362565292422482013355211212833533356597614153259012421155776406163546916134601451529516961660168162245554042856711481627110316018313277577801421186286721566346027113784035083289684115311769131097204185790692718801405108686958585895773337310228775737479264131811351089358195531765171169199263772151544967423155326511111297446694127911157769983447423283433941790114738130238013901189122111321889173436966117791433412138110982576175035214715735871348122617285855734403841941285110942461761839221318759317701763191021217084622511821853569605513024036017021636810101959904378000124114398263625693891630555001693623121137501371022831192217160702671662551311142111316775319122923880125122025734159185234831971812619862444502020255302381767129264026059817632102836461140692791931755492127213620396702010611001990093123375249211006605512271371330310661041057357226053055288607162247248175133814000176797811543427161180327240184101427350188277561952475601444740104585144958406267213501013774549601483068426124120228549046589225802191768129272088731003109185129100155513114417102112173142107021803479541493015251510565135234913122811804260122811471490156001012331323114963260390128332037519949002641393754119384113263614019001136812830235124102484612981690398704837833442169
SP101Bacteria;Actinobacteria;Actinomycetia;Corynebacteriales;Corynebacteriaceae;Corynebacterium;matruchotii3173016561832350178104694230601413326827475176271511039107250354810206928892600241822202173701688824385701321231421127106475413110162159924859469018020630852725140101417813011211469332212211416544310915579969661037856103320593291132147012663762495931017040137000321904512934135613282011028144795121882802774511315150102663715815285687110370878803612357616047610450372017102292313918171504022171200015322538750104141010346602274749501932475297446851211712826193950784710724256019480323261281301618413317230045982140603311326770131560581250656610156519584100000018133106010968008106837317806413895106169402419788012192560140414052441486862728628327126260221520573925193030862681153261028611641172177843115556193148136674132859523977115251460524457494117002804234164341487334821073458281823275207082178234725586308016816848354810142111755885736864916553948236124413949233323168389210439255331954373516704131152104736592358171016912547515729083499957229752497386081393511162160181233041665215446399333601212559644450148420216198402585124515180220325817974370301455126309831241842677918870117351391432798327113220432074404218852697780157141471211010093600233560344704763037675264980824540277130322447991792298414466921449803287221415776271269015553626172299359131952032250134922452203441142228701036715201410641626895016701508559803101111238591366147030225092908351241215236724774375290243638906861348423829194298365157266222820172736053625214501239300135342570947175537021266163261209418162334932430373030201443181805043251266925739204957078478610302922983171326011780358787767532076241719894138206811867313468131982166458544293684223722531204155231827791616917712831589523850214126032383144495063511271148201565
SP102Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Leptotrichiaceae;Pseudoleptotrichia;sp. HMT221060146111690014642185188287912507089001124936018125894252132020029270127007713323680001235141325066047511140100031112360001166029202331071342948831000147020602205201003133010146400027708006251301801829300753006298222537889144000044701420018723070185123800000063964701971000130613057023235198792441112815286683963045000550019510001462272707794430436090640002833664087143000003627113504705800014752005540004414067026013225001470160436236300345000005071055140012400137000510380034820701439248240025108104250003044255000011620344003934101439400052004298045550002740574427901685436142065582203117866136330000000100000032610092850017902826960172102550050000000000003080000009000000063700000001570008080110100000000000001217000020000030400005500000000000507170000000000000000000600000400000000003000000007000000000000001500000000021227000166000090012000060000000000570000094120000000000000004000040000007009000000000000260000004000000000000701909000001430050000000
SP103Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;vespertina0009000000663100290003823001061000000040113220432296112600041960000001900001420510000173018950311000000000000025139001010000001170001530220006009612431440671920000000001080151392322770000005702400000000000073006943000005114008000000000008051880000567005020000023853519186018340290005000000000000023093000075806894920929000000000000466170013280000046002200550000000098325191035917500000000012003413023413800000000378006000000000980022102160003502310300000000000000019000000002800000000000004000000000000000000000000000110000000000000000000000000000000000000011000000000000000000000000000000000000000000000000000000000000000000000000033000046000001200000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SP105Bacteria;Firmicutes;Clostridia;Eubacteriales;Lachnospiraceae;Butyrivibrio;sp. HMT4552814225305528471283103810786161228628250774624660119070450923676215085117041078043371481023995642890129013463732179724008000320181240413345385401903212830290270901013027314010157050615011420908212305601004132558133314208042420901000024490081320004080740341540403128783739299111653017170933315033102934240042474051706541061106622005102433171851745056626169104686330316210000360021847240071852116284071113118019822201203570524155210032827250134357140020240200501512611921992408323854149000310322451003850000805100000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000050000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SP106Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;infantis_clade_43176549143775911337951948109535361121140424106141685337366264111704151879313627542192112047274643139184671090943175015693140736955672127848856377010761009191016096462122615232417823761461675535209821921893916731964014513326246423910105315208954854783853464957547171716322581432122182646991232952137139857159910056629615926289710018811993182304006131228891897598504179118214171467481291132145197168282557236460285480116272266744731016415253761027212941278800250667390584662731441089561949610267942949198210603402442292068046583775111341818175173620214264964771971088899842613197474908147200699235841732229761046546399163964480195390551302928285768023912203198416108772582004202415603211921412169226399724920156253130324928741704316331803702948377099049032704216311391604311697174853939152133465354491466136371312565155471710209394824167915267293204092494285541971586386191176923618314283202679440275380295288670504391159346226296177137826315956904354355129565111132947932183455300000000000000100110002670000000000000000020470000028020401200002480000150000000000000018094500000000000000000080019000000000002740000000000000000000007000004200000019000026000000000030000038000000000000000000000000130015110020009002081100000029000000000000029000000000000889150000148800000800000000000000000000069000000000900000000016124000000000000001300
SP107Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Schaalia;sp. HMT17225612540008646204542414079012649978031384448314320620082501600265017603811141164732093814041156440855783811375072219317801111658105220791226360148599146015540631900045761432269172185077472380018201020176820410338499201110120871211214603906041210023730408550195584133871614013401705141620278790019700534651115127370700024400001271058049852000005935474266753516601005690059400371703262370221299000574600229122267521346888215709670302028383003046085701600081004498952106269051701901210272005262315422201497730657276047189120140862206411521515663600011354505047392524243110116716902050598482307441366153350166762864039610243950042971705560162452829562654503299181121815906076200320785181127480400252344000016158402667510021000592111837666511448580124031230461403188355040961500000500000000050003200000000080000000000000001000900015000000008000000000000000010000000000000000060000000000100090000002000000000000000000000040005000000001000000100000000014000000100000005200000000000000000020000000000000000000000000000010000000000000000000000010000000000000000000000000000000000000000004000000000
SP108Bacteria;Firmicutes;Negativicutes;Veillonellales;Veillonellaceae;Megasphaera;micronuciformis365667811261197193184616113733075826024862593283282152513159403940388947164188210879012294251538373471493017566831813041821631192518120501273612164525532943017711684075301391055242770171275570673341051766860311273827825861114154201391251510931860193361151312341727777134105104089713866686560069390036441424293027512181700136160335848470602241037235049241939215013577667803926939163810370537102693928215648133739443453990765096943860554527155312651203152326566575451612721457811834642400301691252905932042482260668429025124157081091021495104386444362377344328501558931638651104159144852133630200993130132571042191486562353115323401291625330410766111826910481710081280282814514014196586276301520011512413621664127918001812126108684410770125750000000000000000000004400000006300020000000000000003000000000000000000000000000000000003005000000000000000000300000000000000000000000000000001006000000002277000016000000000000710500004020000000000100000000000000000000000020005030000002300000000000000000000000000000000000000000000000001000000000000300065000072000000030939000060
SP109Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;parasanguinis_clade_41133713412544386105470767213607341004168242735377218538579117318351734164740670001317002014363656068219691040928456681202633474672630215185762719886087267031487101555859115401701964719854315284340014059881683143655619317059613310247014732852892501330140910408134715378114382361058179690947718127498599332118160951221617435169715491023111814804289457800103942422996565227956280900234182398158015111034112936600017220412547634706384442165503887909371539381612079192118690213819292561402576828605906138425941345681405690828616181597214745921323103200000109158296180357712481579907114874583590215113560734894249891459207128273135414574355357126663134233707282211597429091553137820920701505270496744817527338473419823197844868914249065211183326022501572106634420921991748257054138902031756974312419152277644105940775584255909036782289895935871264871320719394861971663501019302193046500014011341176732990320631473298846817735971018772244241178110100000000700005005064057300000000070000100040000093300000000000043080000000030000000000000200000000000050000000000000000000000000000000000000000004000000020001110000160000000023332800005827903254300000036207000014000000528001921000391810000060001700000010289003200018000005900000000000017149340005000012100000130000643000000001530000110000032000031006000208000
SP11Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Fusobacteriaceae;Fusobacterium;nucleatum1401406162180315410252119814810526411955468136831243963787016570181332913563451047431129422071871695669962692031442623218437104130892182754081085372391354334751821427712837454036701324608316218456010886391401345267111521588712434425747710591727487236298153271182647595116366388523112018415538814144468346328053787851631112642589234372821057553041356866785824324861957803502985748283694421721031501613354220182135202781491685836361031437429245863658643689632541093691341454717557129318240254166119151181155162481064363532031751025514026912770101151720111647414739241856583864137773638371131461617543111642216082601946844149210311444711445273633124312191189503108123147341760427128811591153524560370214260911472172441109126111718350706885767322211082796124014033856112878417232283289226438118753158231694072408531914270111512123713161194537116317704654712538831733256424858715753021041190315478431777413314695169101634373755845312581649193529736588203122346900511180916642801216239158834901864398331122664546321421801218516641932123519663071582268107210121503169264168360325424114631102030138680213451979018512652100411733151409156549546424616661787550102130862515718693472210826230207412971260207223551837373928200114738531654225534212331931571225220026182094198599698678723568283626152490109063411377101235128057920690891208322571716187321295323842323197567359132735342318100344828153747110067693893115859852515404521742105486132371554627436739178010001796134174021252669283336442265651342533792831012036105822429574221403108914784791658132412120180661904554853298681556826022503261340841111459573823712023931778887159419749201826021542103812745172642498742146323111683802118622280541824347981755806725511811490169785881366341542017520026142910316313613248138720371177211241721023977941455359612337453513327140727256027717142481535421223732851612111333733149172319801378447422771772
SP110Bacteria;Bacteroidetes;Flavobacteriia;Flavobacteriales;Flavobacteriaceae;Capnocytophaga;gingivalis1626202321667111103181573146226614008172326050504455012523191622070331492481870151119230238136115711370829661450887129145373663511803316031379790921075302901611212661738244462510145321446127331247831621120068515210123073159446378256038132633532072168104140174171126103031150215010302223340181329102324088035378491505901351784500024091000234318001511731523991315734232415019001127425302201251043603914231446535982622190134272225367533615188191354818911946318130021372488428494450102412336140350504533845149016513261172515222219494516104349324979225142914547567000292125109665364874943915511442066358169062217710126394034177276253782328831612484591817924016102111138702235146691455416917156650034599190144115238573824836735230110211522212956657493891712514451715510819078102386129726101758069415261010410722441271026623260153128081967634377781004938411335117003189125410374371383053145318115782253579459177593963938105302320153526517961639351184210742273972532067510242877510149736630221241735760453852665621127930133308426022771277141740833437972131317314928127560357140106196249116646153945972840103422118733189734149199161813818214180302169532212071536174102620251916408117038995536962167998352271332671184301121783010459432314760492020453834922612586250569155398219434221173923691342024476223761139430327967372269288241517157512091113717534715511640534125921583121105184657029113361080654342108012742222291226299123961834251073830125116522982251346166396
SP112Bacteria;Firmicutes;Negativicutes;Veillonellales;Veillonellaceae;Veillonella;sp. HMT7803894006619190608225566670772573135051007111217355433018912019848563501100880268466119113116127268063815142000201715120049001212628507944164303914236304712483338020933052831048052485114025249330025552556181609371018548880115146003796931256222925008397039267947008422272402346032322511611113467391040000336000006002610432860104800070430510228104031486500000110302000061505021013100200003207170070083566180192074260188800016404202871600300851273570010218700006059253122240388600003884180006000242741752125700703069427001460110042250176701016000071100012039000010001417800002100000000046000115001813004507320403300000000000080000502304614014000048006000070000000000005300010000500011676120003900023000002800007000096703000000000000003805190000000182900325330000000007305000000000000008000040000000006000003013800000000000000006000000000000008003050000000000000000068100000007000000000260
SP113Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Schaalia;sp. HMT180006157162177525108823015610429527717524062564116277324789263610474910599627180550114176320019960300517353460160146794354436815480195154209541039717187191134110066451852362267686897132451623550816760156620081142831650541433821899101640310913637426124436710068513110002919023182103443624735919587436391331621848100959798942432396616533600605479561610361078150830003393355893127193442319202690003241213633420271502535652022689101385741436370916625182772221282587253296803600308385055004106006925893142542697489662032510291000932312390259941411649165252405145500120060716933012906834432000548283104229013314599466646302907836004911554836119407330002606418192013667822267928746484338923310772766671157323780131985435680244450588321000490375260205241107165737100834621985047202890020000018110051330104229557832576291230000000702221380730960001561723761339000000600258102864283201003422756000115740732722326270048038348005306044800330100270001100714105565603160140017080211020200012000212162900039533310026087371704200001421520070019101801520014000220780550621321441848372024000000107918820500100601000801361070035101003800400000621500906258000540414801070110012103300000030174161700000000126253538679012410003649010053760000700012002120757331400822140170000112023729000210
SP114Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Actinomyces;sp. HMT170000420025006000230000095370000000054920013000406055106500000420000001590023129401530893031270130012670000000000013001690462100300506000230870110069000000118015000150152200000000052121320470007002114618780300280623000000219030002190000005001601300000000001810402200103831800001293754724400262331144341002516057200021080000080027807144080021570160171505200000000400600000000017050000131160304516023002100090802901400277105061313004000124435467029812317000541047036148129024000110185067207392000041882900000145611437193110790882252408907756640700320267110240052127000710015272312567161302059343700124959111423002975709683105810000000004010000551272110140000200442474327911763661652001641100453222339380180000771080000001265337310170713127730002081603702089746316571500571910251681682206400194909280000033571073107248771472620811471433552203943372623516871419143153910069001163254751502006438815014900115913051166636472430407601240000001060022000145511841506901700190144502843265718491247004870401000220225596600
SP115Bacteria;Proteobacteria;Betaproteobacteria;Burkholderiales;Comamonadaceae;Ottowia;sp. HMT8941441800236000252400000013000600000000000000110290000003072420000300110003000006573633210027020000071890007130000701416000004000008170014213463030300441460400406500070040004665840179400001701414400026000008052008260000000000130000000040000000000801890000000400000017018107006100000003631800540000001500000071004001440028000000000012245020000410000004002351826274800130000180102226051270364690109000347400500100003015000000000583023357822371200500060134453000000033100010209653011300173340000911754004140002101300202500025584000002401300591746001300519035040960175530619027108630030051610005800285452471514800844403092690013940422004533484285690000004000000731100000008630400972700006012350960000601436360301351790020140300000017412332310452390071613063000131007000522000002001004400004000001171623021974054228408000000730015301230350028000652120554
SP116Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Actinomyces;naeslundii2011396240216808417216757922133302512764575018681316023530102286301770000000107911272196427631911480105318112018280539670111411081803440616240221343300024092318188917961236420544672731731417197794402116402004752893511212825102852281160958382587181550390912920110104331306560610075107734150220203745253460450017744211003128003048625100122818116242643231170651992120293601710320028170014519545310354418601981617264010932045940302181846122513641151921113463000162100137525203001015614218301942157017223119242381451721322152556169222803130131830262611915484200027126234309622218025009314333613924204902934085347172190885313061713249310731473294619918618810316616161062691919642092901144933381681075231318512185622393613464127748423857476958485325129631115162016303334499351188238817701474921543140728943011832128836275766422691023413925134894327882312813159427791351880441036379382199244746218113471301444402228819051871453384672850436185014443065106467292346114915122760112836620142531442275335207261919472560114541164014492219699108230554998711588558316811214401609114112759141663165217173718618845504935401179372834429410912534989516121339014148042054410056331886101379473314404213224868901869166307115062529916462916377433123510053246771791087799320685927180104795912298004512259949702092657260789404242932791149675174487584762028871571151617294694497476396137533971072506206853002498418981401519611255831079448105029266011041336399176185718957212214305223312642259779326041616782597755577351386025910161111970439993637162013652683512442962554181163312051462231526027216117943457202657521963486916104130110039420392476427303311251394373822102320618645841466
SP117Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;sp. HMT30901702660858805230724616117242810984105524320000227100212268063261320000160312410526263441101000700379056808000330008201403879500220818868431218451221070012130000029214251425002002016300800127721220044009000112291351320124000000003500404018550412145606800206381027770700015721483683934113778023000000187007719309065310000107201107332704000011800321822129000350009118011014042176601170101787073292361159076151000000831041506160214770127040136028281827945065000051227462907381000000003000187220710010542711300800239200000000000000000120000000000000000000000500000000000000046100000000000000000000000000000000000000000003000000000000000000000000000000000000000000000000000000052230000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007000000000000000000000000000000000000000000000000
SP118Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;periodonticum0299550137168803330503244265141948744496100000360398000019184001592724049311579381313527610941670143196166646212370488170039780005610014702450730050000259156189155027102270027040000078706000150212712290100002039301363234001137317408801380150162729540001552230274153106010828811417408236908417373711487136012811103515325053864862121131101526311172197000001101059000067130000196962001266810377656965352017813380710004881120120654474260770014200440128000000155591102570210022700275000000220740013034167397023000044152251910001021622320013590442210472831320002468171611049970553901323670125249016466140402313800000000001500012100000000009130000000000007967810412307000000030400000000000000000000000000000000960000605000047400000000000000000000036000018000000000000000000000200000001001595000000050001961201209000000000583400000000000005007483050000023000000000000000000000000000000021000000181000080000000000000000000004700001210000100000000000100002408000000001900
SP12Bacteria;Proteobacteria;Betaproteobacteria;Neisseriales;Neisseriaceae;Neisseria;flavescens37730520420374456202926271661335012438583298454412838885333100195565845224975334011922280023139693366100031306435691307847485173010814114472927103322224449711366705817591301254260311752129214000091001354039031495050343416496556171652111546741473836000583143236171290045466532971401421210581528185231000006041055188111299733544146141271855057091136312983069240014726411240119589672003214793657190012754495619465829300140364953439007267051225522184776522843191000232649754344764241154510809001644137513724921212927014070164130112173000036975297273104180192889000110424560460740240016242283716646532274056733034011009300317468224922269816360787112243611631766053915435758410014101361581471211800131959115205212119381530133000000034837312122170820155685277291403601489392511178042720002041205054907245087605939957250045456169929863385017204774402410545520199266216506972121070001400248530060067125205600575501492694621124000894276000017113388331168950121000300270061370000000015070090402668288625801930000301447442000200000524126025253000005315022546003000001203580762641000415496480000020058627181570282412606023601480071551050000194012394060001532441763700300604729080000019301211000701500285440120140100016010031201650000001096984000021498824026091419800049103406610041038130693002190000006902649002506060110170000989000000335714300000760223350860126317400900
SP120Bacteria;Firmicutes;Clostridia;Eubacteriales;Lachnospiraceae;Oribacterium;sinus139323241180992195416341353451753631131133352201152291321247210622592436413972501143114118735534291574168161160116282864232752617213814319011310518014138918511272831939572764973504131603275215053294412134437125084946214715210367931410221271150244120945168241145138333117147248335611772801621102792991281261452091579817777643858776511818320226391701644269354903838223148869342401153641274314131547311419416773261662063073636910575421723631782021791322874901556591928452152002621912223082334862241991013016980222789513031467511585919614356285246958820802481939402570561561761177117844660275978737313269763439211899561591001281441058721231152132617130563232061519379433989067273045912018592508330619144182197424336130423273274312567131234324272196239559111214754749104428105949702225114910558283831079915311782310615113923924925171679135423329015321475573738418927729419245412700000000100080009000067000090000006000000000000000420060000731100040000000000000000001900000000470000058000728040000000000000001100000000270000000007040000000000000000000000000007000135000000000060006000000000000008000050000000600009003100006005000113000400600000000000000005705000000001100100000000017000080000000000120000000000134
SP122Bacteria;Proteobacteria;Gammaproteobacteria;Pasteurellales;Pasteurellaceae;Haemophilus;parahaemolyticus17950708971505229004510021283200600054920415745671730420481762575869057801715782581206113970044922112000305000042422331206335800000143324695002911705982190317142032106108004141747685517506766512394699610263082016926626600373354600862796514619256146181140270078160172001281041853101286291461111532162557752774951207131422702258589490257144829389112890112541933000381333406014080961183830324015420127561335515013543524751504371906473484810021379031424520612042016292476635129605980011228412230049104319024996027132172292310711002358234321200419140123182768187315452146120148235578730676171001403953245200108193243838380805509540170035473501144220301143421111317895547733792411982205600000000007000000000000000050005000000400060000000000000930000001000000000015000000000003000000000000000000000050080000000000000000000000002300025030000000000000000000900012700005000000038000281200000000015010800000090000000000000510505000400000000000000033000000070900000090000101000000007000000090000005000166235080000000000000000
SP123Bacteria;Bacteroidetes;Flavobacteriia;Flavobacteriales;Flavobacteriaceae;Capnocytophaga;sp. HMT3804600000005000000506000000000000070000000000000000000000001002800170000901503400000000000000000000000800001000609000000000000000118000016000070200000000003000000000002000000000000000000000000000000000000000000150000000032000019100000000000021000360090002000000000000000010006205003110000000090008110000010000000000001000000004000003950166000041047300011093151142000015102191000006125001280460000139153391933000000180104114100210276011922300000960000630260191605588024000240180045000019700048032810900280000089001070354512311620198040042160133142621200000107200001000020203600100352026500050018882430000138127690280000698005010800001441307416000000179500005801700366089300000000014509020106009860206000520000700000144000351202210117333300003403153004021155128042159000131016077740400121330620000000000
SP124Bacteria;Bacteroidetes;Flavobacteriia;Flavobacteriales;Flavobacteriaceae;Capnocytophaga;sp. HMT33200000000048011040046000013417509010049200003500320120140000900000314688710000001800000905200007629010002180000060500000031009100056900040070265008800110403006055018050002186687006040000000900009012400240800000000000040980001012425016652320620000290018020072600152110000024014050000000000010210600004119907013400000170117800000121305000110000000237221701500185418020001305000160326440000000000021980018181140680840500002800008345318989421150219047095014108415122599000251516704002692133846000122000005046182040600002012800011125000000261548919039605000751536142800442027004725001061227000960014564035134002002440311000711011144600135405900368623000000352612016290786700537014000016800000001412048060041203783992193913036000102130040830044800823310000070114260000010940003523000000145102080014300280004702420700600114002990000004826000010008790900000363262221705603442306110019511215616601309380000000011005338323830005500
SP125Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Leptotrichiaceae;Leptotrichia;hofstadii00090000480322000037140000000005000020007046081800012621179001100092700090122198084430003000000001304107181001100660040290615003306709812147028090550150100012300200115190005000001061700000629001600000000039600150171460057000012000013000900015340000000001311000000000000706104000250007603000200000365163307001108000030282730703403508013010080410015500170002900000000062600120006110008000010131464700111402481670000611796510002170160008000072200020605540121623000012014461917890005105596164906919203343600138231000174250010088258700173000200177388461580235332221340089103711174872921820788088052803414000254081240400014071712977100130060092000071175243203134107900260000014003501222300276010100006000267024000610000270002802125040754690001501777002100000460044003665000000056370930007200005968355014700001674607830212358953454430376051909700033870940242521000010000002600001840000013030001121901148071100
SP126Bacteria;Bacteroidetes;Flavobacteriia;Flavobacteriales;Flavobacteriaceae;Capnocytophaga;leadbetteri329150352802941538758291525639883237135041818753612601872175182475380391111713146433371901781230277318173420358264582217106857225130106410023337397211435512712615511639307011714734972123423591099156405322828205272066023146139145111674478224172570722631618128145412643832762143240625969111481424116520621510574143397484710647121618806114414918682620110131523591172521377326171364622417271113885013218251018228843141238151118489691296236418556015777311254140491023202141638186134401252223132912311460168154631813186108404536620686119016120758913790515119174294114737210931676061211137648512089122271378367413141266186485149920035385219740125519523397585975213442653533931185419311063223322213579111201068514111344091297724208526014411498362509512981346105501164351104175281462402100428554843391361918203246652904321671231420051082922932013915858027522013018539452839072142994659601124428846419357101865869212819523235175360231135517914235616014134541844793911511933601603331540147970100937756868116031148117079234632150271794883700442252105814017111599318764610936111753598398702118001639676543610129450255097186667448781468445392584128402690769644431133125642211133440481472318141349102331120394312120714757783329572382255775513541587642325237150151561914491238188081454612589920115335802321161136139204217803650391533787921178521777020738148411117713721565535104089643991841016187159265018347770659474141876141861121040501866298065116386013440231028796273634942223946332643041518822100819674804041708650511532434045036813969569051392171360388809715164779819066041963251319644847523246106656128612172601362627671401584156771091485486302622470464260045917701099107214362038319310
SP127Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;oulorum83395711375027531433159001407412871500012834904116201860060200002200012113410000821500442296071321317211416870102507004314806101314921105611700688341430331101920814238000269101055320058000000006000000513314010511008002203214145110731001373901314422207201101308461302622022119002728005220886030038290065209758101251356236104260034310641101390106000912261814338001700161931070371213291271188310101415001372170115000737001300461482418701200731170151701718104104013000042129118625230437181710240235035000042752505017700159030000017500014315000000018726131500482030054135000280006268101010160287243190110212118898535202457700065141204283141032017019000548004500001167080314000816000080000034710980522719322017709231031293012620092012293032601477431802508190000014802212182100004301560200068466240161110500000310016000700460106019080000003605700000115110038010000000810429419822942000000251006082581301240010360000030800300220000028959000819200005440
SP128Bacteria;Actinobacteria;Coriobacteriia;Coriobacteriales;Atopobiaceae;Lancefieldella;parvula50667134478162140148245646248833343716316125195662025817212917854530697946361158028798487108448674612791022443354842435227662241397141300157269162315411423705072598234335419148520164520933232633093566164015127661601233361449230179204105343079947631116427925943128566752214357173180994251042109723990455353241276056075033574259417237815312411922966026931757113171992271272219660235130542113010987202743232567941203222044245130838340833127243180446289109819109759536396183513404640232243014264291372722141902831168350033006165831325101307911065471630673669315321839850579151415321518160438488271311406645281501032302516146505207136189117304452409714441528236530156106206671645421891399112192202888486813445720437032332921619020701311151373419745255607210540489276280380863012019396347397347717724101297813654833337164261778123642141432024123921417818616251646689632841400000000002080000009600000007000000000000000000000000040200000150002180000000000000000030070500000900008000001800000000200002209000121740000000004500000000000003830000000000000010006022030000000000030003020000000558000000000000000000007400000000000032000000002920070000005002000000000003030020090500000000000000050030000000280
SP129Bacteria;Proteobacteria;Betaproteobacteria;Neisseriales;Neisseriaceae;Kingella;oralis2019144019053927460456051923128400021102202809014651600050105104126592702317892938016440102133330314914820092111371200710852142701301150150271425247645508144347265482776445841000040012110009205915101500211184636912001091338013311282400101243823441120023522451200000147935526751731528141890728801065114431100566101222619091014615329311467809281711597661520251029231561025116120219430111781147842391481611097542106012472162006230713120007971121375028056422222111783316254210166331113285072058225575212789115214914164923310385343421103100219974901045113329702025051738428010153270391928501491001281097028152422166946446739804213157351352908691821042849273762551235681287275352796812529121111380307046465578798820190111183360241913274779150391398745426380295190157105132100550233593319018612264268111562435345119033735419859485151719096627649617016523827365021423187941716010891996982662113382981341131847315621860895318954385168134443913321371096130132133174299148123897178622927810311790224071235378563821515066313867163159379699329712919189577209175645534279252381291253334224874066739635830631186514355110660163593979482147127057485451633371264191060148403216090912423148051214625783612714152342371218897932014216513656782681931559674075781134528811328065267
SP13Bacteria;Proteobacteria;Gammaproteobacteria;Pasteurellales;Pasteurellaceae;Aggregatibacter;sp. HMT45815012051364223106719707563129492792246351169251400442013401004315601312161858311257181715156297810111419216322352623998163488736018195110437700320138512072038613260262302438143123300388876211305403001754512004200323960156345146565219204717630542309442422443420072034001011087541502852645219900153110105602557014409260128371211611560514500540461993710130126610107117445974677922765011956541090758085210667202268520233831606125050201950224713244694802071591213330780059216924017014724215430050000010511210170593431673699676202900916520742430205627111001680184100160188235211101800120016680005823217722164930227271857519347018771600100020395520000169380118185545241701372131734330083628644145481486127453813211205178198873323302117358007250011604015900019104971004550143803575921845150059145106403114864353217500100058645075574909720215144293698380364506349131572029110205170109001681469860781211917200941880168220014234902381300187261160261700760000338067001500005135500022298003324736154416042510105111015720230001315040200513600079020671754004001367024100613712345011000640025091057270385001310000111311511737919134527116321666602162005198925588003529636060029029001826552511630011150
SP130Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;downii2521797818126920932733920138424376416725483155131492677705016833429086571716158419873185241061225358411010739201528244052620502775557120828119192751116893510497083818701049266264390245941348033842000862166101378194519541942351293423911873685234221886873627698010633016730159921711055112883591982157322646219226312491295884676349524661287188113032346632121795366128023263071715715816448695564701110112344519334223651453343300273432916681507434169030316273943869861128673128427013291724764378293860321016984014036185614162836198159414891716854423622513263446152939012282212650581691285642974970060417811638121922031853092755352702471218499707125767394914109661690278103826644950412700167281360307444432407779526525403099689801122245422672644711510251270147001102616830535846979562221673303020117711021049243003126281595381776301322641585205115310744708380827075025629228841570862224294529510490157120074817467777586573523361749646951202012617983000013411200001138500001691340040000000001755693011000974000000001690038835000180100161000034618000000600007700200600092100000000000021547000000031500145000288022400014150009340090000000900001140000001150000068301370000596410000630006500050001001634019302301070000000020001340000001201210100001808704028000000000007018620000080000025000064700000000000198000322002333000000020473760041009008700500560000004260
SP131Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Actinomyces;sp. HMT169000322171411210834122378000000148366104001071660702000110605929240601801812804641265045168805390438106338000801964000161500042155740013346065002716107370034553710101300042330036438143521032721718501163761152634004811985013126011321901018191493190246121766779370349711547722263103600012030237247155580203000092802619418001720468200161970202529060241721492911640903781882176466200022193235723400013815898510067500684016147151551011010649726131436983620421663240550001914816400715728040741302790571830386782016444013002500146202811668806004635681545730251116112637200115080141591920054845642891317728629193071405260701600512673341382915634700419411853151533911851361002321412784178153171432161404122275988639818614914258369386990320311087063812316781150031874514665597190927602880460018116093501189018911739326270458266559419641910175271342651130600021011304420828449109610591263381026353561571010639557018821042962401055504369674026657636818327231902424791306370035185667137266588192413441119308711412110004849235137170328803144334020391202681206764754944329051280072485305930030055074558929403414243389191702180647861299460251656632151919613133243603850169402391610862815211400039419432109600751863603872020521096911103781133025062611366893791186538882007453560590423166529214264141136772000110698011212296132914862442033465019490445211180480148932539312836403756943774601936185923395042346411258622842107611396529386865101563653148924414148220365642621734154942811012508945
SP133Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Actinomyces;sp. HMT5250000000035000800001221160600000000010000146040200018120900503220704741240794001302550091019017000001286005601216805700310426311000631400000000000008043000000000000000000001205813000002000430000000001820013010003031011000001700000900700316000017600000420050215490046006800934880030400029231200010001420327000557006027030000000000004100130000000000590000000024009400007001480000000007300075450948436154230000000112900065902311009015000524222303640098045800026401107304500140097002720007028283420122000109613163686600250165011100050300063135054284900000000000007280094000000000900000000705082910700162000011528000000000000064707019301280000000027000088800000270310000822830100600111000034000044415001140070002337928300000711026001857741000010533800000001336144558000000000000617534000000000000781000000001001161630001201400433000
SP134Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Porphyromonadaceae;Porphyromonas;sp. HMT93027980791122000582713156254141416412303202911924194717005869015116413111304087156929171042089610562552286462659163487033012807508004080352013000320018411802296949028641123771705111512688941310128207420169600279106766672998210068793752547114812116774592153908703610979211411708819481775543198048917720142511920000152333815151634902273634178624570852801509300000006151330550032342271028051296571830308940187512160401720067029091325497094401320003453209001900980120002360014167868610314247194009112201322334844114139214510086171512431631510082542618567171000792135318115602751402804644149873853007041040103345110538224015000873290701375418516582850332392400002300000000003701600001002105611000000170000000120027450000270029001100031000000000000000300016560102802300000000000000000007000000800000000032240180014000360080000000000000000000380000000000000014000000000000000127000001100000000000000000069000000000000002801400000001400000000000000000014000000200000001727060007000000000013011179300000031134000310000110
SP135Bacteria;Firmicutes;Clostridia;Eubacteriales;Lachnospiraceae;Lachnospiraceae_[G-3];bacterium HMT100490120031900148749721310036300591491306080402074081062560000000000839011460000040240761310220042900120000313091222903003611004516735190000001617524319136259200440334309140151114770001922771820013400140000045011300020420100146180504000000003850000000030347822817215401901230048714803000000450470004140090013192001605005580007401228110241222000312190003540728007034216220011197812001341601052372121400414221323124610240000027540301186670620142180301012810312003219127439679228281901100224000038734116954204943872580876540318345352604042886200444618701383141370012273908221709152117300023156831188075621742110941243092213737510209453330010885423543119841770603001997139001360155199364603650117819353848928433950031871420473422856658000027200324209985123831210901313803055390242334961830600013148441129310525510652200010298601544413041214641111102058916415035168001118367001296026610005806712103432992409206600463987171000881341210100265132167662305921800027401056480018775123201000032391175717140264487431060149129117003866161745118026622148000015803900127289821972026753
SP136Bacteria;Firmicutes;Clostridia;Eubacteriales;Lachnospiraceae;Catonella;morbi691584562481312852432225444188161771074166141914014646582429212210425113265799515046912674422163233221332562410698108112451921481005032115591298716852161203163687733681255520114009245372014532032501184956865416136146915455637946423661548145825555820332928644501311213412766633131324141173179446915019681348198971201810779403981491151678889411905713986128040281430141412827121363447020640042281161286116868973833229770610698105464276326210974732282643508442767630002365361234929112196707784424581911549661333399557615662774195379623176143446371123304313973621433644550148238138347621731353513108596289213172315014268687113420711886101137241968194216122873216839713299148229395332387716025111163974601242213369440831911913515333193363000035680000282029497181922902284013702000027195011039110530132010550704902254260117380061110000380515026003313001054070253156331994645385973000857320600270427345011700000350110012168120770351451423256682886900250176188021000667425021154401601203503400001492860120088559599741866300004598108013175801809314000582589700360072600090000000024160138409002602894037850000001727109813067364000220150100003000140012824389000008236263490760416610157825023005728280860240005596340004300003100
SP137Bacteria;Proteobacteria;Gammaproteobacteria;Pasteurellales;Pasteurellaceae;Aggregatibacter;sp. HMT94900000000007250000000000000000000040000000170014000200014060700600031650001300000000000006006934100004300017000130120000000244200000017010000050000001100000000000000000002800622000000070000000000000000000000000000001000904100000000000000000000000000000000000000000002613132031000000000000000003401200000008010000000000000000000000001000001008120000000003611001203610700900370000003613290000007000004054050000873308990000063077601730600001300000140000019014109606290004049000035040059231401000000157000220030014000000000000000000000009000010233400611210000026000408397000320000010059020000000000080001230366180000000000000000009100000000003800000011001500002941605700080000700001600430115000000152206600000000000000012000000000000155611300400
SP138Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Fusobacteriaceae;Fusobacterium;sp. HMT203000060000007185017000000150004000000000055000000000070000000000002700000022540220000000000156000081600000000001402440000159400000000000001010007800700000000000000000004900200000000280000000000000901375100000016080000000000001930000000000000000000017001990000002302000000000002660000000000000200023118300000350000000000000530001090014000000000000000000000000000000560000000000002089000000000000000000000019000000000000000000000000000000000000000000000000000000000000209000008900000000000000400000000000000000000000000002300000000000000217000000001323000000005670000000000000000000000000000000000000000000000000000000000009000000000000000000000000000000000000000000000000000000000000000000000000
SP139Bacteria;Firmicutes;Negativicutes;Selenomonadales;Selenomonadaceae;Selenomonas;sp. HMT138200000000001709000041100000004000001600000001000000000600000001300000039100000000000000100000000038003002350000000000004460000000005170110000160000000000002470000001340013000000000000030000000009000120400800190000000400000066000011000000002400100000000000000000200000060000000000000070130210000000700700011000050000009000001412614010001702000430002200051371105621801383205060190064820004205010290000120001250000400315028140003002900326006101828016802232011061247040157238002201700010050002900003700019070208342520000024000039046000117172701785154331611142004400000001315135170000287020601980004000024200006090290603600020713805220360100240000330000513090021772705304871900000000000505800000539640154024235260000528005023046600000011700135618030700
SP14Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Alloprevotella;sp. HMT9120000131088000817150800002500502061239300800742807000000130001034120030060000000029060000004000000003011000003700035020000000250005026000057022016096021700002600075000000016700000000740000000110000009348000000000231180453101000050000000005000130400000060000000024030000200070150032001390000007000000000300111240320140005280161730900300002300000000003020000000008200000020880000122473117000041006102040010735000360120227048000000300092900005600000000000000000001220603030000512000911900000000000000520280170000008401301907940354124000000117056000000021013070000011300000012084000020976113000000011087024070602400004500680000030000060000000000000030000020000001000590060000000410000000000007590000000015210570670602050000180042012000000000000000003700
SP140Bacteria;Actinobacteria;Actinomycetia;Propionibacteriales;Propionibacteriaceae;Arachnia;propionica4043531637774006618152820832132421202607225163450169862325315027237051334042915924763173137541731326150467034463549366118171383720131830230443810100026333549527142512670182290164881243412613191183722158222615761016310220322471055291015141165925468739630900243485122215910303434248662642122701518891020018115470027120012023626275220126518636040519100412701100352646104175469403061256908997824577261300190411067470215997022203710068002311212222514216106621743970153817763633289578534262821121212200034298591301340918420168415224111246657110764114033551947461284111163252119323302111631865637801124347120162871583940451097145316421108191517191153370223441413155583029883723631676432862225156329467446216056118451189364167213452652362412658496510802733229153591907330292362732374928118615152921131266136225289275241005681761362331155529061073316196233258113643134982053722146427124380423281012036823469189752263914496452891133027410768319191851104162829239665291016120141659542313598591523757468127376802701618444274492953351461843869702633213712137812811063452277021539003032519234692272327299225838585584305215101034462774063781507391445081341955501708361444508402783273605683846579597636311493771795253170048517296678550487360267597573348396288102337365331043435911507113261701786956440231891294479842686847620042880430408220912529125926678450222326411162382548315128451893864991124449101011218320522463519529242312852112412413478261047508
SP141Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Actinomyces;dentalis001900012500639374541654265093060042150001015001006000000000550000000334325339680114161890431600300000007051228403301350005000102800013170627000224771216051460726639120001003310200009000900001000150200000002300170001000008120180014953150002500123326301015270021013000500000330000000424307407028012000600000600090025635070340040002105001914012000072631600450110025311100000010000400160906316017000135000002700166900000020362758329103766542172123190019404820058511256002966724480046170025859418600750007201058500128139300452510692796818530061150900017002714059063002351603413517615384541105125249170757660187746779800139015360534000011093234600159604323180104027102132890098088720041498013050330174001386680287484872505800185001242000000777120136349052245621075800038605950051586002196510520058702168979540040350000138001370139000239107024733422173000139007007000000000941009825572920511802140930000040001841019002000052401516013109333392664385253215035733300709546140060201703552036080094000230379185000038
SP142Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;australis47226522070132524127118862185766764044510031942451461444220983474549164197656915992922260300537446697695671408113648311481769103802416422496656254522372040083576224990150934185123856165013356681693593830534836027911708122225146451161153425991152333776174468116011372407618139101186181029059383380024360541022357313140110715252427061636460729921228817401006904295621894042693891491527840065390319561070718378420312434281534175584392125936171902925362745814699781671769562662681848515329479141464248505163164263172397010514276825811072117863545716331663545191723361947256794171490450016602317405021837995680135132161009172449128506120115726793263053214193152106816124539215609555592757041432611501041661506457521969047330121821781310917390322330021464570293852624426121987701032143374189300292103038227139118381562226852265677007047513536813786727336501884872489113411942620719912418621058470190684120932035214300720105247750179378102240000035816226922910054150000015134000000002808120250235121792700312016100026000000024396016200028001303001202118023900000001400001521422170000026831800100060080004205434682219009040981324000064014415140001410350004158204402106000001411310688343001532800001424389049300000003800520017539220401910111744007000358237003500095705716006515200002911901860271040119510000026034011093541302204521151700364960159005002730295625086310014904315918000000102068
SP145Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;shahii3080028487500001120001831611031700584833405663215040142000000233150033905000015127230048123806222318227000000651123220012703490078199053164230051085103147601820320026280251900347145040316200000001151370012601793579370015519811308826715105267434175500282711322367768263470010627420110000052201452000087196370000490009726812028300340877931452111404800000014200478003700003600840010217401992700000548493800057003131372352165011015302399173237186022200137120662001598703772722000000802316003470231685607719364166044252310695011171950026940957141488264279003738247000000519305000000000000000000000000009000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000050000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SP146Bacteria;Proteobacteria;Betaproteobacteria;Neisseriales;Neisseriaceae;Eikenella;corrodens7025900022300014220172043013288700101484490900000188244337000134061515312810186610570092712012504364442082756026360480014119205270313921700634217151001313048325521101018117276456444060140201510101017048256817110196130000303321511039916001103908481035641009000120400042092467112236846155360164313210840270060980714780104001705608131061305852123800016101526710160190241801110931317805000197001211151410201371605783704390124615042561680000351413144116270130471225221265701732053161110331762191630190215394887447319986353396125401470385288459398229192180017543699131141941558119350173213812926818379494322313156231224257624969985932941511042056147651199295171113990332115221533943682571176232233302231431406238516110116599121067562191371643434189109141323441351511020613325768152154104677948479213160511012305419012463550450245737026411225617720513162281656395371280257010823515106391882301074012621645197654241104721035191118201373139551521714766261140224145131150175858813315614115073524075195291108322020414317228176253844914731224184096106515921423302051611412761925318828530253782241221191394503721667444146102614762137670207131103735116268385829122190784208612072015011171811682782361172243074468542517178154396918010511092593551933927692
SP147Bacteria;Firmicutes;Negativicutes;Selenomonadales;Selenomonadaceae;Selenomonas;sp. HMT892260001001600140000000003770000603300700000000300008001109140300000000000000013000000110000000090000600000400239003000000000006002300140002511100000141115000000000008192100000000003119000110000000001300000500050800071000000800000000000000520000000000000017000000000000000000340000000000000013003000000000000001800000000023000001000000000042001640000800720009121560038431510181077003612400010844310900270511201702950205000022002632907602412044014050009192000073000211981760570502902655210182603304701600029029190000001102550120001820010901003487353306217000100012238235000000291062716150180015142261071812600933227000093070141210000001391922000293518912200023272640080280110001100040000100047636770164019000272021000015204010200051511100017200007500000085716000000045053679019617596370180069120017301110240000470310005615000060
SP148Bacteria;Firmicutes;Clostridia;Eubacteriales;Lachnospiraceae;Oribacterium;asaccharolyticum0614900000021300000062008000018280078480000019000003044001500170001162620000002593090432905610000000000015340000002943000000000003900000000000002306600000000131029000021000001004000260260031626023000012000570000001793000519023400000000210012300017000330000182500100000001901700000028000000000000000000530000001900004100240000034000000012004908836043019000000005200000202934000000000008900000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SP149Bacteria;Firmicutes;Negativicutes;Selenomonadales;Selenomonadaceae;Selenomonas;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
SP15Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Leptotrichiaceae;Pseudoleptotrichia;sp. HMT21914729000000000100006000000000006000000000000000000010409000000000000000158090000000500000000000000110700600000400000000019014190200060026000044990329000000000050000000022002000090000000700000100000000000000000000400000000000000000000000000000000000000000000000000000004000000190012050000000060013009490000000310000000000000700000000340029896300194295036170004001212118060000018112064000000000162517000500009046000003988600000000000000730131000000600000001865420008490000115035280110000008300140002531148691907019116431220018000000020600272155018902811631700621850112380002706000000004007400000000000560250000000094100002500167034000009000000001500125000004400000007401609004200055606600000000010472424120071119301551640097350118011400000000000001480058019
SP150Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Actinomyces;sp. HMT897000000000006000401200020001400000000000000000011400007000000000002000000000051901400304000400300001060000001059401503011000000000004500000000000024000000000000064180001770003000000000000000000000003006540000004000000000000000000000000000000000000000122000000000000150000700000036003600040000000000019000002000000000000000000000144003422000110000000000000582000513233290000001830000001324421000000000067513058301800000000000370000000340001603272600095106400013173810142202890024300001920434028351439909540000000000037000001500000200000000000006119422101611842466130012500000000000001311000852950000000870000007243121000000000000000000000000000006000000000471667225111700008500001720514836300400000000077900019130000000000073000002600000600000000000001941210006941198342002600
SP151Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Actinomyces;oris1347903214000295801132102510818450135911135002140094149001938089741147928150024927116610058410054027992206080493729717181606000169312400019007000331830810015614055263065131339121911021472712050005900704235320916700402272450000150371231114750112472512077501218800010000028741196030881246381002901248290141204013380920130382394280100013301690059280283613635412130101630219775311110001397128362100142810040016171011037250036191201720761200579230030422018101217000000590014034200000179060150190024290160080343431187409584767093362110697621306374392341563273221564406136021507186237654261312370340188383012009093696143185808360110552012768140918196120360523510051694173700012481829555633681202993010091601423222572432641736830812586462047634143046010680202673360422247138175165130045885798245001704191064791611493398901233328324282318184320595821754948942212636192193004344801107711241800108352153903024617382621872313415140823097242981091493560463489121014182147411472058506635198461123228161455010422681519076691134651663491782311517019827837227261022006041801571741476909791443129731253792910710881439128491164737134612052019208314073757843401502860214731917714712254110078225822497881148463435346756505010714051471152161530393102901571522111210024135112533028324052109235429227315342131352326016655383001441791039116437000202271214323343325693717134165815652878329
SP152Bacteria;Firmicutes;Negativicutes;Selenomonadales;Selenomonadaceae;Selenomonas;dianae000000100000015001301100000000000000000530000000000000001450000000000000054000000000000011060012000005800210000000008000090035000000000057000000006600000000004989000000000039000000000000000001200001400000300000000000000000000000230000170000000002600000000000000030000000006003000000001800250000040000000000000000014113100000000000430014000000002200053340000001100736257010970003070001880002844054400044001433650016400020000025121001300000000000002900031003234800997910000923744003500003704050170008709004429001702000000834100001014200620000005129743090426012000124120100038113803200000003434508000031201111300327001738301060003611001520320000000000003302200040001280025000000000640132500380000901490000000000023328037000004501325480570000360000079115600790000000010800001000000
SP153Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Alloprevotella;sp. HMT30841652971243691014682276911010721025242020833060252393144387090172003780436483053541985896705203451321482415309045304432033922672646115656281044754364041819311101229725188085801956449622620771565221052024861016544091574131521761852846941865501721418811722135211255123112428247111272610512332334415833516112231547021050251861722120122182512403471839114002751128431311441437911228027444314324320541072168710204166147213026397494849511216527957572012345021043445493513034009147914234530118103363931279438753614331740909119578335730450580326225262556462725922762431921734801698108697290597263834032830116041564686927194127969132430116107681202549048628652286207451261099068953371862771993404057166210351058425443004791912855692011539530695952081418571538010141666897601408182331588421422376254101343102183249114570104673160008000040013470110070043400000020427000400001700000000070008300000000030007000300001351600000067021000060000300300430014300000000000070001300003900005800050660002117000926000020300400013600012007080000050000063020000016000000000020006009480000001000000165028040081331000053830000406000180010000000000220400000029002134150500110300100061220009171207010830500150500170
SP154Bacteria;Saccharibacteria_(TM7);Saccharibacteria_(TM7)_[C-1];Saccharibacteria_(TM7)_[O-1];Saccharibacteria_(TM7)_[F-1];Saccharibacteria_(TM7)_[G-1];bacterium HMT352122423813282829063311032181351127082443012366294035800404329144280144273192666377575559706601116221222741555691022174280382450271306713491117244405484151751273003135393566309368413690930681469177070313288830349561400290188201911259783439543822663239119334155050414618483882321209379966056177157381241293281637277753732964252101132849194379155360216141439663673821293200811226705486111987740630131310380742156619505753642991711774862030890114665560792930301367329131577916110769379169524014081100014513269681945105519618429015718811113425110952422414912711744368544511722119815566221181916414720640655056885025124423559109822071612671965748575291506238419915511505214317532264151420362940514307843521249581851894410126322220926425836253121154612201583131887390443233143859926255730248426588606711240426040666023310236000000000000520000000003000000000000000006773000024201700000000005000060000030000001400000000000000000000000000000780000026001900000000000000027040300000000030400000013000000000000000000000000000002000000000001410000000000253000000000000000000000002000000000000020020000000000026000000000000000000010010000030400000510000000210000
SP155Bacteria;Bacteroidetes;Flavobacteriia;Flavobacteriales;Flavobacteriaceae;Capnocytophaga;endodontalis000152000500160003300330000000000000000304000000000006000000470010301702400080803340000100007081705300943112382030455000001010112610054020400030100020400000000014264902034608031000023200020040665001301371169098220000001101170101313000008380441000001101025093902000740271040003200002501234056002905258000123016000050277110070301000103000000000200200293452330203740471400260531930026181642601046823924139330174067019590007303702690114284440300000370224103096602805551201616807241701181922540000000212134720512006073603500321011562155780003110438526331480188139560014900979045142005920691931001100953874000231430003076275007518910333618026620634000292110001915570006182542217393573667211923360646165500462135691060000000380721041064235430000019394439095104202038271310308498524430120000000310531339000335300014314054775265003340015295184103073768500380000275289624964604806130019310002612004805110183740050460385700023309294000112557
SP156Bacteria;Firmicutes;Bacilli;Lactobacillales;Aerococcaceae;Abiotrophia;defectiva60979003172135431439223018410142189928035027920261337368127205119710660165310866560139189121806319929116211516920445529036918810127616317123875691238831903803713468120573571016755604261441401341211499586320358214812827352532856312031124321143712154699466741379514249422330618718948820447325403334859142199279907771192705739715958151175368148420923368614829520732157429361632362831328139813727502481334601351846900130680150001966313601572003449001720001737750025842032835771120105441102079239356361132003399206800648003741330092708510312388110024020411340265273524024284200140004124113074603212081010354215163291512023326015042900101085871512610415101001880224023007653307860819589202300005341861811631014514310641244661615229305161135996545280547560861440733711711325264522892671052110431624673257334223149513203439421172032817171271497273821090396147910263309686169116123382871217879130625718289896111119309567616970149740992463911482761650617385644233718484143731627023804402632474264764513741385584973816276966413962232131379061938691464605642672101553595709218155017416030288283792281124361486367164146317731995101210751732403742840028394797991959189415225251837542174542521161214240428975146602375190114062411630308311520025239781640094284032398580219171520005381905689408660018106198721601666393104214656182945415184217314022070480404322002897062554700010803030004192013511369266880166587761287201011637325188511857117899014600209848188660101902332151020206410534308262323324047336890188745007414417286194423914925436724079001845641762780161969487332733612022400310201242914224413854842864259012953990
SP157Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Porphyromonadaceae;Porphyromonas;sp. HMT27580560074000004936114007000000000167556000000000000007000020313220000004000008301608035001000020000071360000350000000000190000250000025129000053001701470031403200262510529050416532400000402708870010000000174451100000000100142205013383800000001100050030040000008000004700000105000057008100136890001101000000001600009700000171200932000000008004400125030142209002502612000001014790613161400531110000013200923613133033000026001203850000191636390000000000008000269000020000000009600047530740005001312026789600017900000000001480000390001001890000414006604012001400805293223507402721718140000044016001928510024700000015760014700000001322000831580126009000000005000000008630000000000001400000120130000015003831118101180000000000000000000269000000440200057000000001114003750790330112003000260000000312000
SP158Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Actinomyces;sp. HMT175843203521016013007095845747854910112916454212970030043311427152110504216151925110807243156297012485910515810901153276014113204221930551146043152997024727000320068531457201316720050148600960705702687121557616078193141298041071039726704622574309065398829240106373810872509831251011029122405314202820203500000337125575131825416931075041811251230112486114401131246652008843051806199173010430001552107551682332407400100500338203361131571134571614022121122106002830701540516251610242413112218059133810189401422817115033261812174023504250139308231807315123854746355926320178335321100352694451270020151339566840040077517340405101243178224554224820833527441021242168107242210695231517328701544327130550668912167663835524519184252146782152181411002207079712361386365427256845165695198710951478591551059727330071125219491283309186300766116505648085841087533381309815002639310229110123731577768909622613625531628241621031002443428382251693236019400522281640861259821186415691034314813102786671604224123217910731148728272045101238355406553642870027314636488153511319033981244964900053407121563108829192717408303589622712818314192218841925211093172997667266426771080594494343286615393242985024443219527929764342117747154775412003171339153342178293550081728751587721294529339965137287631393772292082028790431581049226454276285019098933074344164513261762197216062084168154381671105215921591595415236464912040727771710234456302557392883144317950258214048981655155921294158944358557241158235439421162861359371533024361758791012681213805701967533742271884681569153599
SP159Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;oralis111321413511611932012101413104771585861248882971061034140127105911771271180300105511428423895715719313735798348841772484258760915572411422582175129125642471194012010188350018373295663200651810570694520592271200350000231217955411128116612133877357368294131402415095376490278892104578390219222447441411035661461422418775063098284930017169767481221618623420369926147365811217241391194238230241200129088548441106490199107010910116413013469258596314125633001784012926013570834265525197891487622393147104244584757255543189402133220201112213300542017953882459253013560052563479793318501152401196231723348376102614132470150022848882514127231274240175512447141585417210932377374695564017416535582143284280264108171301252175113838653710555916651120790364178286251944702707496312630619517146134801036481134174245943225093431713466159666950492101935212410524176414135305121417401734290638135041743501161500430981746206643611591004629236418076786143550147917592901269116894072011091351054746651110245927110100490234813551300100122637666550239156973710610118577000070722842182077423111627113311794474561346256560427276321352381633179123951041323452081315145983060306176591112081934813242313561399106711486181171539326605018423961167730212013283837298158102168746080556570016110729673801393708466012486659910616451923321423109104819548702078502141324394820935597193136845612931032836207542511184203229822523281594148839762421046396342897400282457592086677115195662812200566726365877961480692677114337179041221165400155419810274004008147030894300167415564678532966728619273249564495174618291899026120850602384305151234269614204593802732286112814701626014738147107389020491960126528157134211480341989101697731433713656161892585910921060
SP16Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;sp. HMT305020795950000371672906900281341035401630000001610172811801033230003450083990150001825055010321172411503203700010100000500090220041714020011600040230000055141530320370005004270152304900000004600000000000000002600581573700007300964491700004010041018021131923002881000000150865117205512429000465400740600019221200123128026873600121100082170001400056500051005000410283804090000342496919014514085007874151245095100000001803706116800000303814078007516043000085000000000000000000000160000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004500000013000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000400000000000000000000000000000000000000
SP160Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Alloprevotella;tannerae000532200600006499247510701021168017593379003711500418000000000500000000000021003500200000042000720100000000002718109152051940000287546100000000009000301434001013619146251614063735600399050184024180023990000057183496810000000023390008293000000015151740650193715801084652003761332332000000000002300000000030008103250011000004400061311002140800000192142471010118900003510105900000606004000320334007081968271180251230055502602250629117110728300000446438911100000300211600000000000008300180140390000250000000000000000000170000000000000000000000006000013000000600000041940031000005800000000000030000052001402100330000000000005000000022257000000000211000000000000002370026000110005000000043000000000000000000000000000000000000000021600000000000001600000000000000000000000000140000000750000000000007000000023473500000000000
SP162Bacteria;Proteobacteria;Betaproteobacteria;Neisseriales;Neisseriaceae;Neisseria;flava0675001322560020856809013477600530015543204352780322124158001193232000107072005141333457020142511133000080101500542000313367803847110000559011753325892000040135423649001154410536622147035580212396061713582227634053701298636870300010250112213901330002144136118528941501511790117265744234243937796200544294065703780218698021400002977761507902700386233003710009691570000797220014102404115600915812500100146004174151710143650000000580000375009510408828080000100101860774005423129876415882783030000010800250001998374494341240001290000466050466416000935901759539409017113501483587105232220400019123698036518823470245691013500000679619155505405590057152333001196930232465913060394002352440073429054227319083800746236700231830400067032409414904090449075900009433750243378000468601012421500003250931726462980179200935611717940291006344492261424561102507464053424606634975563501035944068822394185200046190228517902300013326772832725882332075953206774620467723060801672020753253082409139201215202666750000566121011270715059001312556001750009226122011400127600025149162150010620026154480006212499003632513587034484830000001500001394678001303860129930056000010011425360506700193411496198910960883054537343200005157070000025162230335894119200011700001781098071040200097195095416512066011182991011450791126400841000280619350205752453800916459397400001305237196021055
SP163Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;sp. HMT3170014000137029160475010190098310000000600310000182113015176113822935260453621002100223101602065415702900030017003900000120124008601620001353208731602815100281850202300116325000800130938350017071713100011120900036742854917104624750090280013010070400014330128005302100056000071112808011941705519117385211709013054313441000801011011724909100000490601334300001415007404400901001250034101773702742031600669100111708014473004661531051000312018000194130117260418293182033220700550120040049298011890452153203106399445500001034016000131123100164440141200268940754545065573117322380157078050434594784030561437298285132040403340150005214515490001650056189702840002360125705027425226325899783131633117446370277850014007382910008320831496205800252274005045004028336219320001102105281786045210415811330090410076027150000031282142691877021904430001306680250001931801903101947007361595321470121384128005480000300010754306107730147513505220561176931100002232530630005682488301370000008246960197019559875401251154904420002217009061450981912643000049014929400003000914000020538245005014448206120254703
SP164Bacteria;Bacteroidetes;Flavobacteriia;Flavobacteriales;Flavobacteriaceae;Capnocytophaga;sp. HMT87800000000000018300000000004191333000001000000000000000000000000000000000008000000000000001208000000000000000000000000000000000000000000000000001613036500000000000000004030000000000000000000000000000190000029000000000000000000000000000000000000000000000000000600000000000000000000000000000000000000000000000000201800000000000000025018300000000000000738000000000032026166779400000230000000000000000000000000000000000700000000000000510240700000000000000000000000000000000000000000000000633166687115300000000000000008690000000000000060000000000033171415000004190000000000000000000000000027000000000000000000000000178000000000000000000000000000000000000000000000000019702453000000000000000026400
SP165Bacteria;Bacteroidetes;Flavobacteriia;Flavobacteriales;Flavobacteriaceae;Capnocytophaga;sp. HMT3360006000005000000000247120000013020000019000000000000000010011000000030500521470000170000000200000170640700013000038000900070000000105001000110000300000500000000016000005000110000500000003053000002349902400440030000612000000100004000020000000004000002001200001040000000000000200150000000003016010700110000000118000001600000050008060000040131103544103450001050000001175565028700110039148200148004255031901270380210030002652331820201420000023497000000483832000010114300026317704902100200014802524902392622625000001151000090896410678201144000000819122016811327000051000100001351000000412102021295356007600031800000068221360305100210815800137895142506507001901500420002482806068470000153233000000002780002143320001153391120700000001916925169477103000002000070623892992598910600000060911340134530125006005008002062000022002500065802174760270
SP166Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Fusobacteriaceae;Fusobacterium;sp. HMT20400852842095900331406602906236390080092612101600400094500333631547913080142434003251604901139162020164132022310014805351338100194623313270072685461151002022880521621205822307284101211106310461040024000027710212023321239011360029419001000000011110002880071025400360740017401006801300221013600056001728044673201145283401602104700100450187019191378709803343001126171802251600600300600092917158008214200065033107211352414870023141913092470007130133519770013214120562905422078190005001038140008300642138803017732541230340219208468700002070000000900030601884626702231264348270034010603301373643730158177035010827009278215229004263951067032924800745191097082526910200521671311820734228000620116341447154511073302741305414183719405529689290521971730143125154229012283133630128493001891321174220000000060619600755487480034104721181500126017600038034003701790013600005010225811064277337880004500100130496020215008583433228135365028638101044997005800100942304806504008401201640000000010192647421310933161244501070034073018940313520869122084857743041330701792100423772600000000024633106
SP167Bacteria;Firmicutes;Clostridia;Eubacteriales;Peptostreptococcaceae;Peptostreptococcaceae_[G-1];[Eubacterium]_sulci240116181402201031761520713282166599257178120329600332217120966479119152419752713212966205271145117979433225659601102111326964671652182401091441219445662163284150025590307113016912024011069352542116823862174749001645020926272090571543450506221047817189842402832215993125252250111081212371726062904013631562109527142002909187167002013861422624749198135723153111848232011415226651759499002257102101551111861362091326183611999608420085660025011311979241197159893471589988124920154231886848163823912488132385610283768841003813516725640196716714489156233227612902728114322803525813805416986561632382001901195911141261349387632001739921372307324638325333425571342051531238069101582065018200000000000000000000000000005000200000000000000000000000800000000000000000000000000000000000000000002000000000000000000000000000000000305000300000000000000500000000000000000000000000000000000000000000000000000000200000000000000000000000000020000000004000000000000000000000000300000000000000020203000000000000000000
SP168Bacteria;Firmicutes;Negativicutes;Selenomonadales;Selenomonadaceae;Selenomonas;sp. HMT13739180000001100180000100220000000480000000000000100000000080000000006000000000808000000000000000300400628001030030800000000063700000011000006003040000000000081000006000000040000005000000000000170000400000000040000000000004800000503000000000004010000010000000200000000100022001005500660000091000000060000000700370000300001204340001531600000431191200101700210133218000000191244010900007300015054432112403170003900001734174055110000323003507201200000004066602760340002503500080142023250153805310001497264453031000234407003032473052004014220079500000000408683307225690900022076176703734010218001290170030031093000013200001882049038900169100009513601343300000401511060000000001241512000019000850077007737440000180003010273726194631200001437239101001418291000005000231219150000000006711000033743725000480
SP169Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;sp. HMT42343374984760156014704254456323169091459270323804323779955029363348368292543014960130102216869592900129116621805403233043962316143105788301424633928142021259417765119122412964678025121113713333322563864281220043232247553447638431626319288251852412213438612452747820488516617106613218621157309214705029291218291059897313962151312242191710124649060010111298182204231506467137820231712010440385000433288452148255401986933739430661101913642501538962317224127727383412722473544243953735191041033181851545587972383927639314435214394962368541422785024749910371424394145605604697121617144436465128925751055048739693274431647621103596342245610287782795217611050953481461741314706112467889289353416196102127135630636057313996236544203173155415152542196503145592231168246715471701411823532411081936271942408031027034738542023735828209393248623418630513262230207019444950015514379171881440396117660103107553168887134911269494413479394216318372043648822439627269143526218338670146481811220127531161392735104010339613093131360018116439761544235524593201433131108561888156918675118038271279131877845112320112063275257498328208601106362712011522907325999901343947884335656934401619116151352110193981332321761596618540156118871548794542762608611939103515362791123109301498963169501954592363810561099679149512826444401703003009211416501280180894725012064924556108734283010151748184130762816061200866636191630420023634428167214692385278185812032765157374056214200232729161095273367363972186143139515422382217600656661171311621608195470881159548421664606577704228552264354270021072992206513082181907615492521571857744328684475030152171218993766256173421618190154878017635210043397920353561723040407517156135093342930765955211572311020191697714585717804421753421192043822249545746390914734507851944610254745695619609517214890414061019571138181471164121974951867653109901120203164763843915308056661474469112631231033370240322497527291704739207450219782253495320861071671730
SP17Bacteria;Bacteroidetes;Flavobacteriia;Flavobacteriales;Weeksellaceae;Riemerella;sp. HMT322684412542112483092181073137321225759305252643170137681081227210089554811113351045710738556201837273115117192618988471612935265412338367617311214814487111356211037254703677585870151182119278435174212317719144100681143766140341288335151472310255355194124481012866337174131401546183133127511011821014571355525150997285228145581051351754933539107637247393730392515624199115959157920186158180675211924151137840921173112918788108139391611467359810624535542921803583306926491831105596232211028673725224522345981178883614739924041032227109113147521271313666111047611822438331343339427029465572197247331298633920120102381263322096673146506520432116129148107241591892111590173069281346434419436529636543075215910748512083342786930015499625147342772657932130416436174240133482114940261134611666197777921417271371209188997473427512214179178168721010749189443389471381921288727880301503998691883661155132327758171273601171806438372994662683311963032122946821541514297922836748113778639398921320634915462551256915918957443333039526353392391619414511525345611540818718611127795130269691102913242545134307983054221661043188741221443575888365259417146280150152842515118154312953909262634274022852721449723924178051164710223131437615380025772197445901425015139312243122124184505129519399883344102513955222394922692200180163042673885149263326227244633723522935114400757045422020441023748641569615331789128511327127312281198500901275922165151142171821308424480104832942436753431520147120480107351671225811641412292174201113932971042311294903910371113079020711742721140507796115434
SP171Bacteria;Proteobacteria;Gammaproteobacteria;Pasteurellales;Pasteurellaceae;Aggregatibacter;sp. HMT89811461010101600299018300280000000008463068110131501900090016017000002232408500016132006201366550403507004231001463704232802067640004113918029007037810400001153341030510043341213110091684960101901117173233403730482100000450272102800000100012060020360000001300000000050003920000571892120000002800080000128000000100000026099000001098001000150800000140000000002350140015023006021000040323441417022100160000084600038100000000000283000005210013315780846938526116060531234022579274030072918160189272247270155862951190032400139674530048004841394813143010022870126028855761742584597404400299990021583204670029004838142425240001712461902236232428530202902800273585958314289045442401053719197679439475911481382358096215541037234428829700000592055776160390080179014008860049137102600061630014875000009100065210037015905641000000004200068000012936000581201009032012724601799300000091600090090000500012500180000001050599307723096005006000042047641365284132643101815209883115022016935000000017001511200001666055
SP173Bacteria;Proteobacteria;Epsilonproteobacteria;Campylobacterales;Campylobacteraceae;Campylobacter;concisus186385114526331029349537839049125038813334222711419070112315149303281001412292087169121692134192497195142252302518072467195137761581733102781682064061555163791722271252777218683381574771879391613403220627424864311833290267231284311893083992491133304711616152469712558137178200160216323266491273083512574314051901051237425011218988406125441621819926246728266142161712722612847523954188271044675492281561222661641513336015773456298545903481387414423011834554210926043734631620631716242013027645416933432817214851735641396717620327229592547122114133320168117442115167257026448356883442169733331517513497132032130638019248960418220480645749388255392531104910693902483402451380805150231303211661736023301613306831503734529126821936933858022224517234280400217566151823675513040138925835988821423005594383101526144323332251092313161370164619338380143525106734349514520612925516510489382571425502946101738417265004051511909621843091420151816209119797497169123653142225382180077034003360260169480201844189132460240432143961184915431713203010322253216233571031042700017400613662179096163312855612626474016776378321110132249009498717108250331278946012891850004740399000071411400030001433169060601125375415973122202276126588770480619012825094401274262105372333081410002890800518451490238020727760246371932053637166067130420700052362875003115150023001102993170529782133025006793601418578061290044001653121073716516000000252075312601282034601160003405232703320350188011521101502334601721920002900
SP175Bacteria;Firmicutes;Bacilli;Bacillales;Gemellaceae;Gemella;sanguinis37417134581425399015508744353003062615572288531214108130374844231161192157277360874220110734011032743721638726836869577109412613736545223023229849718959568356281181560463414133052715724255069415144273818651712373953227360012923080304691092315413819613361245161537346729113919649531818731892457169724133198995420711011952803477418373243039551068873177137790141405490323481761128318882569635647406413470297577436418291042156403663138964963214501134808313106940123454753454978920718310833982801047140211961893401866889659409721003296902295713538169972172815923143130520711924946698684702014971034895852964084622881597621232150910940624018120124643922285015191757023810878581012503237555828553253776111869918871445017282162923486371743541092702697222149127348719161364326594122939647386663638766145942678694523753315816342843126743017395588213640128111023456376205976365032176631188276913515794544596507643462927864609705107015619676421182838168320131645674574320918867153675611386111018853997001002075000350320003044869800670404000000000639005400040000018020000000000000000000600014700000004000400400040000000000000663800600006140006000013121407000000001166313190000090001435500020000090327004003000220040000004151690600002000065000000237400010200001329200520000000078011170300000500360100000010011000000150025050550085013005703000000400425
SP176Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Fusobacteriaceae;Fusobacterium;nucleatum_subsp._vincentii0000250000006000004000000039650000000045201937110000000010000288114000798030000201130130000000000000018331900100265270000064600300241240000000003600240140411208400003300036600000000003504980009001316016000063000000021039000000000120000000000086064821000000000050043237002300000000120000004000000000050000005959000002800100251900000000000044000421416506800720003880000000000903816150000011104014000000000000000016002300000000000000000000450000000000000000000000000630000003700000000015450000006000000000011903701660000000223500005270000000000000000000004190000000000000000000000000000000000000000000000005701760000000001200000000000000000068000100000000000000000000000000000000000000000144000000223800261040000000000000000056300000002600
SP178Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;denticola0042300000012000700100413000100230000700006119130000000100190170120000158900000029300020100000100000018400189039510132590411501370003660000410225001100002707002400565000018100000162930033150427026006110004200000000004290760241000450016000002200093732100000606000123011011000800000014200057010000600160003650467011801442105042662000344440002703164001500002401300290020250000710000077874600627000312150217900023400000000004704256000000000460000000000000000000000000000000000000099000000000000000001000103000000000900000000000100000000000000000017000065100000000003360000410000000000000000000000450000000000000000000001800000000000000000000000000000000028000000000039000300000043000000000500000000000000000000000090000113800000000000240000105000000
SP179Bacteria;Firmicutes;Erysipelotrichia;Erysipelotrichales;Erysipelotrichaceae;Solobacterium;moorei139930578401225431371912718837283218156456238337282219018549204149236102174131852810515457253518971229834114981617659399189104311601432435540923490136203192428742213652147105124186327118417528437208619446371771812024136402242253519327612611724724045262401391653651242064465195681801546124168204781126311844413649148223612242592562903005432115621015283722121445532291819758431021034603002093840484596317620292271889641235552064111376235833421871722597132247522106641691729620103346189294528209135653818276229285183228234966648768111281242871421552822314423824012334432107672801557943264488261198135197127324242023743629317696957614338227039979551361682921190995252150421013588220840137542361404197212199127359238155645231519111943116521829310455713957735385111162522951654602372042228311182764623762732141140900000003280335013000000050001040000000035000003004231000000010000213000013004000281800401100000026370065650014230640221000120131000001000005001600070000002600000000024400353000001410000000000068086060500000002090000300075000000014900300002000600230000000000710700000350700001000002480000000000034000000007001710400625330000000000300000001214400000000500
SP18Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;sp. HMT0646112505001350045700985111221000150134040819196344120061119086920900015102085702733207716220017263116330076017339026494815142130410042304032066860530241693770017188014634120452122180005090433700302781382600247014076914000093300990014304069848326540801654356299614221167737923017449087673001583214783370000956328623477005017125015943851511100203492790531380024108597000004825660253631024021562531285300002193571705510596020271288102123093096169136473313473245720846710243480110489916272871518159008114915846160354247380560008235149030081932900731695934790001491379750000023003282641817490317013667655151277371231501012235800286177287117153022039389102540901235001848023085800006901013002115000108246351211100210846101829290365915740007223117152518852114250052319457678601002039906731069098107113310921518039036027800689803572010143169073076503014004434921068000164100004501900000143510010001680510370371200012477014312375500763500139114177856860196138591465720270300001992591181879158000794608360368618076981511644300000316450120337682565709250000104573108795134232001941077313562568990352572059608732242423618374830315631953117845907220390505629133873120121209519683013487053902838202212248515917400460078806227300179166217200000253904332149042512702425327158034567602886098001380383117110677302141661099533717912153800001060786346
SP180Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Leptotrichiaceae;Leptotrichia;sp. HMT2159323344580134122718215322585381434818420836737942928101922310316160131382669694215562267100645332522843413834731151461515241924024039280248503541211291757519148423200301742011741841313274512315702436380297295273182425335395536255258259453158733191075332561081400342211461119923950362904580226519921241113543621120365301212487478763416236844162955430506113030783215514315482186103112624976434516832948532411001814065448241015273113730221465337341150299037845512147536301386558014483052362245516049134203937737934701241218220340721911404880298105139161959125217752352301301707411884426150922202318103233143841922761604228243198508327468326118235237109266266167927764620517330179161360231540339140039520300467280112347715319925120330846398431937020066738315912581681052213692907021535303868184374833601055117903240471839417602120325571099146271158126461424701500077052800023353613970621914085086201454125757037000513211442140022001208871315200251350693107196250238500039004012027001023520190013030000210501134113952081510061004190914000155624723675837900033004832129911529190201807178227005146529062171003753242496103031091935212860130888803317001040660380927954020118008877033224480694401503509089907133302143106998261400550450029000028401092413317106411338203400000261911003310041006396002020553318952009021601337115
SP183Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Schaalia;lingnae632764132064573742511311482741562720511019221523364772311932658368492412454001339832230099125164140971542405684092020580124120103945119735947660414435462441173193667147301209511376184814286180152042121637919112619698641001951091052171821751637220224317614047151149685585220216375356073335412438612713777777861526113129564951713318712114323641114693110151403081858817766111130174238284247494134120201813292386032002931491732812234463191901763725410210115846620795074817074128101420132374283951863769043133978622830711985701146878317395514673942822212102475101372581201901023616917582443701624335121124304810265116344961921851138977361025073304121538064269209185335837262321882091763501028012324436198291374877020412670102932858611810010729659219249298611611885513211614587191670792121572038112120490209209407171695294000000000000000000002500000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000300000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SP184Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Porphyromonadaceae;Porphyromonas;sp. HMT278000400000160000075123216001600027201100213160150701118251100803000120000000037000007826000001500130000013260007100000000220400000024003830000000000000000107201006017002714250000210224500001400000000000000000000011004300000231234000222114240001363580001410180000000000009500000102716000002135000000001600004500000000030000000116115000000000000001000300000418000110000081105300006000000022100800009200000250115202203300008334214390040431234600002665579002201650001500206000000000917000000421151589000005955000041800001000146000000114600570000000000000000011030192000216200395511700002725403100007300000001200380000000000114201800005820195000039228723000993222106400012634000030000100008300000140200000011620000800000122100070000000000000000010027000000000000000000180000133000800000017103900007000004
SP185Bacteria;Firmicutes;Negativicutes;Selenomonadales;Selenomonadaceae;Selenomonas;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
SP186Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;sanguinis10148615668418917176108113955887740959526911982297104119832168335471221545659611629534111850294023324234632414142901354186071571003422452083221282352751848923110312884269732412494315713831589958701137379419716700106153419301312123181191835046241603115132102301182202931010149633924418394311936112664612082213912745332547421570518519566506742975932492717782882604218502167628130830965951824720575837150333114663502006691064119824721834888295212652909241297146157171791201438211162497128013554739711841231427744771991386152879223617752481221324916372158123819615434494253318274344449768179888274864611242861679469355166648921318140636522096111244112505103678366871485230310653745353727534224912041142111521531536398166434161758377678675110136105715724292491723653104312525342740315842121119121117621335443110595409851483755114337597401111512716628013224340810810097132941586526217247110452202254175217011002085196971018438668554644851072949612964467885122154097946139818453612661002289029308132242127369040261628677278912631805611629736830369921441756730164810837332139229799347309090085954201365147088115963644215911116713150430276844843574408313653682561416811814377838091002496201386147422268781006844967911135598190349391826717927160943272459149076124139515917560392838623644369132341873277465220612232437120626891029433922171054918937011178988421601079112344274839816512337321114259566758783462242185468058135543794687420717871576663999285846345274546971381750403461628627625319148527773522229837852465670340448012011450101575854358576410160552567411385017365293803971021969166511771259541440962315233484511982339216881725776901262942223018284484186275740883489694151425618601047837561416476372416448211626811362703142582476319521477395244364131128451880911765042830323571158963331218378164136115385316191368942436417755282064192476594865231181417141484123260680956601086330726974557225464732160956121476194538161362198962063249835758748168662711066912442562034160160927329962492857215917661921332355146620542043189119571708986216439222101518801953653474051448464444136668089809499600415637224
SP187Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;anginosus004120000001700010217351435220015200000005040003723000284020489544410000170240000219300300300000601202000582040068000530026700063020113004706901540038200300000000120000000000030281111093709113001335002722000009200000004612432416918000000040600065500010220200946344416000300000012630000000000061009000660030160002002800016552615004380113013800252006510003000000000000000734325144500188300083200433000000001110002702975813036100027000000041000000191600090018003030000000050000013460000000000000000134000715000870002700400013200219670000000120700830000700060000000000000017042714400298123900000000405000000075200000315902530019000000015000000012500000000010300000000500000000000002000000018404110002943002100040000000053220000006010300281800011000000000000000000699147716200094682000000
SP189Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;constellatus00003700000000003923000000000460002800000008296000023000000015524000012000600070011003201700002724044000006142416150029011656000011032003700000000002605380220000000000000000000000001000390000000001900000000130001900000000027001523017000004210700004400000002300000300000000800000170201002979095000009151390145207016400460016039001700000000006002002401700110000000000000000000120019000000000000000000210029190000000003390000000000000000000000000000000000000000000001000000010010100000016000000000000040200000000000002700000000000000000000000000000000000000000000000001750062000000000020000000000000240000000000000000000000000000089007030000011609000000000200000000000009600000000000007000000000000000000000000000000900700
SP19Bacteria;Firmicutes;Negativicutes;Selenomonadales;Selenomonadaceae;Selenomonas;artemidis0010300007000805600012200000000006200000000090000005000000046000000513500700090700500000000000003002027507300070300020000156002906000070012000000000020304071200010000000001340000300005165200410210000000000800000008005000000000360000200409000495040000005000000000003100000007000140000011075013004210000000000250060800140000033001590510006004000000798093500280488481055192117861292800015500000162475003400183904762152008396481200236315224334002600520816001500027815720343018918541362801680504717600391582010334031102311054012000058850001175117002100112357300724000111012850409411757001283000062840050705595062190048327588611143183015310005600000016780000002417222872900026917000130000190000180151018029514001416836803701010069500024357005300000200008001131691637319000042000101643866001402400140009719900003284273010797619000096180700230
SP190Bacteria;Actinobacteria;Actinomycetia;Micrococcales;Micrococcaceae;Rothia;dentocariosa250221521212672941763042812867102815527396481084020226049280797938014164122081441459211710652018620144001001921578913953749174138307602632408301805913779432274712579874019499134015211393400010192681346434119915760186695154002942315339266113229657617126661738581115118227122149241551228794934681516963616915919254360532581241641811415832935801685106541970472761801136746594251399911584502923221033186217321720371112728164430249018845199471491191214167115561015011241913215584702496251680939511848655491542247926116628713923924350117761115302941122588331510310812158233628017646834741591101167745933916510000245360146685342846471491455371251137381317316561959251000682531130198743781294911515716197255387721421772538120278536378133808669259172523512671791701741174194263081104002121114437324038359208800381818291559092315114758940323711256453122311409301167702601038532153256367777303953877066389137148422261712402861496543348821448545421310127047001074386519590002311825189660419708363119425233536200459146421181310060549018644927767110436091461537177572000611268214873317892269710493658161111184196231277154908159586135741781497028037345127925832195526262891685466086131097131928615233894001004810025415353475985149191908290844240681510392493563492880701138934501204720426305398420996590170219156283831481157097770124112772071424418855215218116003694610213623324296311072703870023541643770452141883604964418861165038381402211074753803042996750588021187135301283575277977974914163868701241322193203726501164118801279902233187736217893912863202499433017961262423238055166216180000162871931
SP191Bacteria;Bacteroidetes;Flavobacteriia;Flavobacteriales;Flavobacteriaceae;Capnocytophaga;sp. HMT86400000000000151006000001703000000000700000000000100000002000407000000000000500000002110000016520090700289009101100000000436000000800100000058001011850000000000500000300000000005000006014095000001304000000000000000610000000005000000001100091000000000000000002190000011240010000034000270070500000001400000020003000001604038054070000001600000802200000000014000001619000019360036050020000013123001016022101150210900006735500002191406200000094025000100000000000355980120480015499707730805013013300805000026200087051360002789329800196374100303622000010500200221240110000002013712000093000008008805000000006360000010270000600157001120000000240297000000000000100021000174012113000140000192960011080000181170010001008900033801380710521339000356112080025320001605600001274070000
SP193Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;sp. HMT47510047007033000015380501800200107067111000000000041000000000007000000400304300000000002700040001370050000011025603615760000007121100042600330030000529009000000000002100000615350400000027017280008000000122001200000075700407000050000147000006290000000000927080950000000000240001400121303000000385272200326603000001645000080029061907002909221000000000000000000160540300000034011333210000000000450894000630024400001630000000000045000000000000000017170200210000000000896000330001160008000041254400122000000001201200017200016460113000150261001692200000050670000000424300000000200829820300810000000001002200000140000000000430000000700017060000000000504000000000000030000000000000000003102040000000000001200000000550011901502048005412000000120230000000017000000001500
SP194Bacteria;Firmicutes;Negativicutes;Selenomonadales;Selenomonadaceae;Selenomonas;sputigena3040090006120000800150557023183006400280001900502206300300045400021699149330001333070009018660055020007809110100043300119050081786000000580600001000193050340000000000083274000000900401705540000009204016600306824580900070060054700121067040000000080024700020000628200100005052083971200049008015929003600116430400001600029001971800070000020320270000000265027303411300445470860050079809503826005644599560516068000144800082504110180200000011069001622000106803835310500087001350001443120265063018210003000254261322937405827009371201274015821529014000022117001606551181102310319000990012400000341592153003768150099320012505100124701284011181628865802602190360001580027200000290101301300080080282000000011000000300003080120000360010100846845160009440000000351651344717400000053424073894301544050000006361002500000331469800017011970002630
SP195Bacteria;Proteobacteria;Gammaproteobacteria;Pasteurellales;Pasteurellaceae;Aggregatibacter;sp. HMT5130000551000018804181069591990004000800131074756006402120000000151417740004016326816029707086923125060030019488310000000912020486400006985000000062363000686620877074061601838241050009495834717840601014119059803196201890002302335001907504973521727484617105500518361770000858000000200392800000019736203394009353176027000256127000267201405604400076360159082804321000000000661411661118014820026000000001104537015001420620041055800000752410134025220927803520003000210461900520690302507316019516625101653334102300003852700001291038577261127160700001180216384260000322652460000040687481340038181928471005440496061069077000405636000000001481093136270330063447000000000132521800029220000503280134401764222060003338189735038301123812360859721737370000610999600139065102626747442480317608336004615623000005247000080582090016300000033383337643912000156537401120005584219700018202303101500017970790461102813180000000824525475291400603922000000211318220041600129005824580045000000000157329318530518633618186626400000960760000173065022410190020454137774037155
SP196Bacteria;Bacteroidetes;Flavobacteriia;Flavobacteriales;Flavobacteriaceae;Capnocytophaga;sp. HMT32300000070000000000000000000000000000000000000000000101400000000000000000000700000000000000000000571100000000000000000003805000000000000000000000000005020111400000000000000000000000000006000000000000000000000000000000012000000000000000000000700000000000000000000163400000000000000000004300000000000000000000000000002602202800000000000000002180000000000021800000000000000000000003270000077075114200000000000000620000000000000012930000000000598210000000000900000514025606000000000000000000000000031003593891910000000000000000000000000000960000000000000000001800037743262000011053300000000000000025700000940000000034490000000000345512000000000000000006407883852400000000000000000000000008701001800000000000
SP197Bacteria;Firmicutes;Clostridia;Eubacteriales;Peptostreptococcaceae;Mogibacterium;diversum27151265221361623096214254325111347865238843281487710533234741622948198110252115822723314464015943857285615018819025032552131236122851161811023114958223021256118108601850685147126061118266314363252231100865801604410724312846343533463091133935427322737541110744016102714673815876151861453617128747109164353813728718159159733577491139633149241441408020668362753106233462254414419129166138229186261821391115317112123573294146031231181228767726376605916926012513275218105111222831825013370162409761721614131177261114225851262582185311794676142374106448823615723715723411223212401435837032255815513921318688898915137610845385216690254849127291715596486721342171983326110153411092571181221793950546599553812372658161151019611160933311103561008277601622641155135400000000002507003200120000000400010400020000000000200000003200004000016000400080000000206005605000000340000030017000000000000000000000220000714000003000010700001100006002000000000260400113300000000000007000000000300011030000000000000000000000002000000016020000300009000000000000370000000000043300020012000000320030000000409000000000450
SP199Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;sp. HMT4721050090006140285410823033200310000009510700120160990014008100000005013000003116430050270081314340009200071800150918163121600811391001940035490000000270132002100001300013574012251614002902601624038020000001621160901899002300402507315003800000000011000065010003923002520124500900000001562320000207300000000290290001400010075018201101207000222319000000000150000001100000010200036401800000008292112203009370000000000181318703530378052850004601362515463245046611010104580037004680081614900046343905313613054520240005100260297750000861335121237601272191009003260003338210036297197040088463634723305801501525600940035047000350001462010600000000192083152318680365174010001375254058024334091000010114958337602720721641130014507402593601081105930014582034403130600243483800024111300911386130000652357780000280000116000700391044700559114000830900034873570023005000921602601112031430240320430000000008440033703000000080875953823922021339070045316192600980062800000002270008641800
SP2Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Actinomyces;graevenitzii44552857112180951261323008374834626521657553311611077234468752063397783051742573150602251227875563924852601525877248120115114961532165109819641400334110933137034116253426187574376662067765420144686781533399181466226781127168994304261325777464525445131523182126379821601582756494300147115220214108771033913313471511402065756716265961005589233148114488181214893458872506621674622822625842237587315420293234297417761492281295556200629841663279213406356237108609432012805311405340925958537117542652041283107221611154629638433564950886072243961436303904622662172795978811156786118727863151801414182991898311304812512632187117303372488195143023830158678252677112933029280669117973489521921908346388488578889745262023410213038627225305034903153312581691501118964017970158125147987428812453617841665431680475928642217499695211197849747171326434519901479579611359720430253828920240131334193057326916317832959119828702110834696140418895019110177324100000000400000000500000000000000000000000000000000000000000000800000000000200000000000000001000000000000000000000000000000000080000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003000000000000000000000000000000000013000000000000000000000400000000030000000000000000000000000000
SP20Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Porphyromonadaceae;Porphyromonas;pasteri148944997660268955131870378635647914741542783147016433482362271358800137938370438112930396246854441418908799120513412676611460102930523342225169151121134162119879913576572525174718927471282154511564972673921721414191035134806271605208845691100329145626885901748256363729222714723143460277078519491466206405115290610846091735528109922892671977830230689414114334562062506525183092431616493769175619643710689361046153685244294209527302349321794227397082654321281594366317062554187030641382333278131616747339568914832270021520610791027261837756623919113317381214105666318482112024311881345862215704540562238513263753254640403842499501429882508118287365319918365128724032621293714190195836720264220099915115922231781595522061713176272001326268766510618001732421600239823611224741144289685023742477870149033291789149162333222144211852383111237211100167678537331725456945180220147155211116574559056822662175721582383893801723123835871494863569368441392051890594263010228424152355939373585122460856307152176755202819032566292219411436701308904615974526138131990232913529395428391359177723014016646942813242941134997162620450015542095837322231767561045569941357396836189391157444519336352021821428519966035814191936514431333114912626037846015300258120695221404822911112144597535101793131199648368971610507483105463154519587168418830164142432920489381321256121002012353618104132089398443342352303360529044116163066225949306704052497335231543525101579422121172260710220972581224081130037862583755351156104053470179086514862830627603187971181109684902724441697203051284300319372293213823366206031062108308941501105718840530106013212863001166028104773604007699052900173148885800005005675453434114345434783029197074805074164367716232415343445087936100073567054315209513755200648009301221209293895904351910900
SP200Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;oralis_subsp._tigurinus_clade_0701600000000530229516122003400000392196351125000170000029000000000000000001400000000000309434000240201000021000000000402667000000194000028055000055200000269000000022000003000000000000177758011122932610010700170300000040111040345160110040027926325397000000102001280000000000000000500006000000027102175100036060000000120000000623775000000120000250920000196000000310003400013000000000000000000631997729181141840024340000000000000750000264214382000002003600000000001510000000000000000000001600000002500113000193501583000088017000000000800000015000080930000000000023200000000000000000000000005111022707092371849700680050920000000193102000461004860000094340000000000029000000000000000080003000000002760650049217752127700000000000000000000400014000007400000000000019300000000000000000000000001481330222282148927500174500
SP203Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Leptotrichiaceae;Leptotrichia;sp. HMT225351270321121190287181415411288011029271025719412222199210320471029000180086300240305100010340170153032229910100160121600560031000803914341131363300300006543171401168220011001745013848091480821600015283375392210409961064661132332430000022017422300003623526371500013159000001700900002201001400370011405221281200000000150000000000800015500190000000072085002702006320000000001100003734011100000320092370000114018002035613220000132268100294000002605511000008427110245235618345378443024502442320512949746288330241183025043068724722492226942652255719759749985144217317732811178238794372966317558722159149189363051721246011150201525186118013762456000086098005211081120533109104146288122635396782307235401315066621100085550220289728142481106024633305451232010605770585492171837790117700193111713228220735013261193404712119117665224549146200001017604885261321300014021280036832029447000168932191134032100592000141423000027019608601649110053997826461624224004107761624774072867007300007640006202860581275400800000485818160000144934424713571408303272162214370518000045443880279135700119400597000750112305245114143145474586437235123001315942337040089214700000100015400000111109390597
SP204Bacteria;Actinobacteria;Actinomycetia;Micrococcales;Micrococcaceae;Rothia;mucilaginosa105223752763361214293601624201036901699399142280554417604241040134419748747572026726297919082138130739249289271920901303142361552432305518988769416955111070274558821828114325803371163216101445945425725102821247328241988535711011463293818864047162828622178272644433377307326191029792017741356113288267778932327147835478618723554137231967864229002074268142622187518126329311170952128017301579223018602836296346473419278812942724158423221299465598516651415130113811365721171828154613061112435976584679292010361276176112581043367922777192213141132266721532423425443779288038194366157314962464154359321830158632312790279421684246362615184531140153220831749731151911412091378846830541433141130021422153817020524259153114197684293165165084319642879266124208031702973946433951752137628151347351394614918992652365518462731440915751320190479144232871559236428352355188921244767166124196562174865844426122982817105312873819941154965506691107578219061453178271271682195314041806858584988109213001476332367831670100237442422917461146794262199957846081578130927110972295300668381864860320856512171553595433419987535465635905511265373991460503158552140817401880218351445117459212923135980100676000015612011210060000000031100120170001401301064140380070000100012010551932180131251827004006000011012010001600000000900000070014000000000000001100405064000060870127000000000714546700043000000010013055400300007970003604017015893011980618301030001293659700019001714944801072180629427042924147150251022110035003141900470000227000003670161040360722004016240500001449417705900071077779580265000100700240637850001000009000279
SP205Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Alloprevotella;sp. HMT914963201030195300736464746295120200440049938842612188882282010575133471871008437000004701855813195054040414418507313101680137020417100912601624247710713669491522020413005387380350247630342334301900000142870110510686181315087653015054061223060101601882228310044531602700000602928911600001806204109353400125160800000031527843140190001913119814926101484012171401343000290009110067211006006313001281222015778932702701430013800281655780013403654700449710184141102000642554360166900000575440003013301728003918946735893706925184211909910604055240000728476160000022322156039230002022000000350262737000003319300230000000500390000000000144024000607000005210000300004900150950403900260002152000013230000000000000003019000050204222294100220220500000000070000000001300482900152100000037062140020001130114200000000500002400000000900080002000000000400001492200000150011000700290000000000000000000000000156700060002100000400003200000006000900022100
SP206Bacteria;Firmicutes;Clostridia;Eubacteriales;Lachnospiraceae;Lachnoanaerobaculum;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
SP207Bacteria;Saccharibacteria_(TM7);Saccharibacteria_(TM7)_[C-1];Saccharibacteria_(TM7)_[O-1];Saccharibacteria_(TM7)_[F-1];Saccharibacteria_(TM7)_[G-6];bacterium HMT87013170132114001982711373774736823274453199990062125304761121713332116900193979956211418825838130001661296621959181310281028561438191508710736900301202101253519302132423450921601699170388620015225283001562892164110362321020001330961679525761341406292810184231426070002541414735000001013210971710197094974473515571040144330020017307013521129482048000671731463320181401231223017410310335034852519655000120171797401460176976141687311137106631401844056242737056001630920644601102116374552420037043001792152531802500152070490079184179121150197996914859302127272602404158531100000316951937711397940432600184017800001034000725001910060012100000340005700911000021851940822274242120003000227106038227400290000210080000261626107071361000450501460204190005854000594656320000000017000170200000400180961280003801626860000033185325050400614101206500017190000007440580000008330003050039043002250452429415215480000800000002605000110011350020217294653000190397180005920840800000050000300045001540000060008200018700028073981040032000000000390114001431118176103400
SP208Bacteria;Firmicutes;Clostridia;Eubacteriales;Lachnospiraceae;Stomatobaculum;longum092950414850053950056003523122190432898000001544303619271010926358370055815043155171830570002395000652981873810500237910350141056350002003336711801910000010727102400111100200124213432722770190002200204761386001720000000208000000000000003002180320491076923501660113003042001814500089292007400271672141332412650000003540032491712937581713200267688011012945000053112000407200441900025830400943001746760420156940012800013070249072002734000021917161441611952002121004615529560245221000280024002400152000000001610911302607722767811413423302850000000000001100000230040000000015000220000640000170000018000350000800120000790000000000000000000060326500003163001859004291028000000000001500000000000000400000000000000022884000050000000110000150300153260080500000000364515040135000600005000000000000000000070000000000000000000000291400000500500063718805000000000055000000000000000000000000010000014840000320
SP209Bacteria;Firmicutes;Clostridia;Eubacteriales;Peptostreptococcaceae;Peptostreptococcaceae_[G-7];[Eubacterium]_yurii_subsps._yurii_&_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
SP21Bacteria;Firmicutes;Negativicutes;Selenomonadales;Selenomonadaceae;Selenomonas;sp. HMT1360781152643371814226572686589236510808313606012101372063302612200130263031675261005018508834357156631711511201612412090116122001034120194534202113349212012011918022498949191216910101168942151361103080251253539625152239693110107150272657599061985671602831845009201000612804121390047241065000170560483663635314634121034181260281135663641139018940241201990730417201609778466149751394837227017033891793509412012128561301212525185490232174223904483163140486281101177190101167231312915918511112338324361021870706610688189901124491647110145173458628301936246952900108403301344215916169123200251601937173148054551054951309143102214600000000002400000000000000000720001000000000000000000000000000000000000000000000000400000000000000000000000000000000000000000000000000000000000000000000000000000070000000016000000270000000002400050000000000000000000000000000000000000000000000000000000000000000000000000000000000070000000000000000000000000000000007000000
SP210Bacteria;Saccharibacteria_(TM7);Saccharibacteria_(TM7)_[C-1];Saccharibacteria_(TM7)_[O-1];Saccharibacteria_(TM7)_[F-1];Saccharibacteria_(TM7)_[G-1];bacterium HMT9570000062500014335136312193322430020011007230180400200030200041831151528157403737060371072000002030890192400010101001015252742900632644287026044016800411530001541315801630010396347053201016445000566300001362228023003000004004017640000121081211143286011270020703310302100000301400016753400290142304534002222500000000440200680077800760800201840700201207064227190003032130017032218148001777102500025000001887431705872600043040012010112000001931679813635524433843421814931866602941010039702805700360227056917370121616568406892971504343201760161013710003751461240000016496096122265214702506923527315002480838829302271110850185190729101053039880044100669001760164302158321740425202214613682393730986439610020586872700000012414700337502540189064048004005018036500174109026239193191920007120230001222519408442000178063118145323026693762220061883016000137060047268000600033036802490300223213251430083373815890980536360302903693216001081896234000001233146621627402546604059071048174022000480177000003803115030176240000000
SP211Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;oralis_subsp._dentisani_clade_398000000000000000000090000000000000004700000000000000000000000122110200005800000075000004680001600000001900095000000039262690000031528300094401708000000000000000000000000000000004100000000000000000000080000000000070001010000000000000000000000064476100001200000009100000147700000570000000000000000002925000002436000621026000000110000000000000000000000000043012000000000000000000000120000000000000001200000000000000000000000000506000010600000050000008500038500004080570009300000001991814250000052012810000350206000000000000018000000000000000000010000000000000000000000100000000000060001800000002200000000000000000000001700000001240000006710000167819000000000000000000473000000000046445030800000000000003700000000000000000330000
SP212Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;histicola5924240819509719823322856828239014150126917772912182513888501121314890010136417997028951346414956508123667834567113136363214274491762157984443246273113955383141201012071565111923137960075701017584239138233714621003295492407460739618356456132323621183972101544300184617299411844427852683100572315371151330892641135464158102264512420114563911930156339153550262674702340021472275072955210500602602571047039370104117491244319513632001469013294632026139826101549848182160678411452980746918931192726398121131124602503007401182153218332371371111946613745795423222317441327762320815312268359238813855147292635018321223119480427553218819561094059180696602267128160312548218476952177120310061321289583891084731753827514518345785102346408259562894000122479983583829899474401026794279111945140201206226596121383087422008140530350706651169210515475040652119752500220259081410690371286256201183015203349149657014720571749400000000001100000401004680000000020000000000000020000000007000900130000270000000000002500000000029120000000000000001000000000000000000000017000000000000000000003000000000000000000000000014012200000000006030060000000009000031000000000300000000000000000000000000000000003500000000000000000000000400000002650000000000000000020000000005
SP213Bacteria;Firmicutes;Clostridia;Eubacteriales;Peptococcaceae;Peptococcus;sp. HMT168700019039000442794726110022004752397631170560000033655019000007230009000950020820256221230087208100025009370000037016005100002704601231265938000000001185015012171822095777915820576402332445100222119864115950000801200000000651000380400009281157639193000350798252310400067000605272000005000110042002812019370141582160002002846064507008590200123613002364410003632753905300002625031908609322588045131736246065303300323912304946119042037140300000110170000000000717259585000000370894730070028005421140000000004000000002140000600210000000040020000000000180000000000048300400000390002035000012008454050000007503407017300002120000000601093000000000404020015300000002113700000800005000000000400000000000000000000000000850000000500009000000137000000000000000000001320029383003310009000021002090570500001400000000000
SP214Bacteria;Proteobacteria;Betaproteobacteria;Burkholderiales;Burkholderiaceae;Lautropia;mirabilis4195092066415089251432563612218939335814742147314125525316951104743105141198211823069102119670581324911303350658302649445337713641541451671892767547892107581549068211155018662374345776919161015054332274154618325353311041938152051358125105111190336416180177134835296226552526314429524256333289213629157338205262127735732141387217374233806114021413418031796017142118393292105983167610717138581159430797356170548114202460345312031611261043679514211400461689342170168422615729500530403808712682542816425420135831413621487080102105251373017181542701847635295293832373085106166794328022261918052932525052884880471902229795533371543921559903582333635716146811689126592501513715451167102391082510913184898951671878133311974541581211925185203554658385753739544104265715100151134114851315363112381711793535228031241556228539984001365217211996861348104630332365850219311093861046505386019131661464370525971514156532051132672261618755329362251290321356976910308132182364038701796884155573103914892623556681197147735199671322604341095116588106847764788895309696149252532840674099462801017961038930322416111711017451096414561306471982179455016502224196711509214238001414243794631541177338369267111152294433652681173318176013814060978711939492638283221174159012963461731943368449120357157292377949022633201710337762807804255225237959677460892801210114192004674377141930665510141725410483669145742746346338176115006101611638226412126848258036531280266153427271319985022042517325821704670891190270227807611612130723014149199283576178413652752734171253201838153847646446391334072071986169611989812322102955221977041034144829440711115416411877111707192720311301385575231927518498156971246411040066412301273038113317111180207046711142825148525522063235107250715881747151077128719538396339802792565143710198174559133833034461128208
SP218Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Schaalia;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
SP219Bacteria;Firmicutes;Negativicutes;Veillonellales;Veillonellaceae;Veillonella;tobetsuensis00000109100000000305940000003833326345400000000032000000000000900000014000000790000034000139000021000005360740000123800000355200000000000248000810000000092136800883407000106330014531315640000000000000000540364000061491060000070054496000000119437690250400000001900000000000002200000010700000089000007200017150008660000027406600001251000004081080000000000785000503000000002795085501115402000699800399127242900000000000000000198072800000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SP22Bacteria;Proteobacteria;Epsilonproteobacteria;Campylobacterales;Campylobacteraceae;Campylobacter;showae187452301291230151528315040161726040541308681113915932434003105205370195318041119212573216624238231395693315094829495533324728173548122017421300341732142580841557013496215622166101027744326020121265656241575215581137186140161410485158402152573504039328444014614291019165889365525133556041241685340710156299571518260126018380302107191249037762441302692763653657116661518886691326111268515144105800244916710111241810201031310151160912515283368918672815331477925017217639593105758015054953010118144422701473092701679506550296776216993743474205334292011751065421501030110431415905068939300396943286902374403454477000826320491377465561698342176157781608444252301831145437776220272996336139984300445271434389375701991058458189795291735525217135732288104430160921522310004483381051646175793123184457411611807661941454663745120210957343046290881469154647192813064001171654252475866961383413311114254845434571625410061430864491675615157329237221418914117920031119092191274167429463539370505383670226219238355841270263963474511868829834286373531311152939636131401455492221982033101298742810828761384506802971381341834114814477173910514269014961489075371969406723517617141831001472242020956934312551150232887318862612515716032136127165524316403791040341030152164402712144115685915642650001121761442226236242244345174301578301302542195933246418651582228383424840266141356011260570125445306103313135773
SP220Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Leptotrichiaceae;Leptotrichia;shahii00102000006510400103010010000000000000004600000280000000000000000000047000745000000000000019011002002000403010500000000000820014200516000155009000000000000000000000001031040106542190000000020000000000035800000660000520000014000000011001000000000000000000500001410000000000000000000001350019500000000077900018701020146000000000000002300000000000000000006094183151000000058701180000023741652007325021013152038100001490000012901092820142800017802741531118873940518145000287000000078320980325187009480012660000272427940720926318582867000213005581860159700161000016880522155517040034200301001112445004860321004550016120740000000920000000654871391073238817862560014018000504018123830000000061134024061000068800000037219000001620031621492812728201110000000000007210000017200000000670000042801474003031810018302960000000000173311890034250000022811123461467930243401758600000000000017800000000000192047382673900000
SP221Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;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
SP222Bacteria;Absconditabacteria_(SR1);Absconditabacteria_(SR1)_[C-1];Absconditabacteria_(SR1)_[O-1];Absconditabacteria_(SR1)_[F-1];Absconditabacteria_(SR1)_[G-1];bacterium HMT87500000530000001653057111812905300682031293231861088027160024003900275000000012480177028140000048410003407045700590251155000156615827801400002083583038476006290000003330020066122500036451070413298262167027034661521600137896067502675000000560598000000116020000014716600000027521555144300001410845324138432081000200230012335402000015800000020660044166000604201020800053142127861500077290100590159362000042258002930034553000000130667940260069483100054310831929011012211239358006127684605361760000392092021700000001940000000000000021114422812800003401612205000000000000027000000000020000000000000102000000005003000005015000000148000050000190000000250000056000000301102232440095001133912011220000001500000000770000000000000002002662000000064323000000000000000000000000000000008200030000000000000000004800000000000000000000000014520000070660000030056302014007301992820000000000000005000
SP223Bacteria;Proteobacteria;Gammaproteobacteria;Pasteurellales;Pasteurellaceae;Haemophilus;paraphrohaemolyticus00007200000501312915025000000361201400236870000000000050000234191682279022006900004904600000006037000000001120000200121502191643790000153600286012000091250076120729127092800045500033360267002255819000000015960968080312400000350002700107202230100000001150060070890000000260002400000074183000401433007620460000000560114220000000000060400002082000052130000071380000424000169741314054500046280000031000411920000000011734702831880601200000014000000000000000000050000000000000000000000000019001700190000000000000000000000017000000000500000000000000000007000000000000000000000020000000000010000000000000005000000000000000000000000200000000013000000000206000000150000050000000800000000000000000000000000070000000000000000000000000000000000050000000000000020000000
SP224Bacteria;Proteobacteria;Gammaproteobacteria;Pasteurellales;Pasteurellaceae;Haemophilus;sp. HMT908131500800029027141225004100098120000002720045013100190060011311000004712403400000349032507110000000890901191900008003101201201443816118046000164001380015150390000594256396403125312017100024370630040631394600000325344364625875710111700301200000021007000450003290000004212503102950002105403060240000077800000000000000400000008180372324000158268000000016112860000059630000016534001400039251000810008640007200321240272218565000006100760365634351470480000006000000000014000000000000000000000000050000000010280000000260000000000000006000001600000000000000000050300700000003005000090000000000000040000000000600000000000000000000000260000000000000000140000000000000000000000000000000000000000000000000640000000000140000000000000000000100000000000000000065000000000000000000400000
SP226Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Alloprevotella;rava00072908300001282039166016000240000130046072820627134600000000000000160000120001417908784380200000000000067990000002307518001102190005900230000600690000029173911370290000028011100000226230000000001793501900000000000001112641900003589614192926904090000180001259066712040450000500011600000140000000591148264151928100000000000910917900000000001800002592684001000750000000011001201616700251563400000506100300043433620000000501414940000006000000000000090110000000000000000000000000000000000400000000000000000000000003600000000000084000000000000100000000000000000000000000000000000000000000060000000000000007000000303700000000000000000000000030000000000000000000000000000000000000000000000000000004000000000000000000000000000000000000000000900000000300000000000
SP227Bacteria;Proteobacteria;Epsilonproteobacteria;Campylobacterales;Campylobacteraceae;Campylobacter;gracilis740400130630016000061403000000775033000512000010800000000870600002705180008647461700000110060000000500060460011470925311061516440507001538890240300017110010000006000000000412433525445157050105050000000036689004100931160000200070001102300900113308008003439000000180700001057046500005412500800000001230053200828057433016090022609110010060100161800050001700000050025101427100061014001605321497708784151264484802090918457441112920405013600242180078011812452617513301240374022541716106055250051411774316106723351911112659041111000993340146019002261107340901871113414345447155030242200886106241601416621545814690000663240017604621966000782372500114156052944311602110211112536023125710052013733291223300590626006061865073635701100131045635110010400441113114850605065582406413002469213620109620029005090129360710009045672707393911510704262201280051724053706010716300015006119245182111261880703822918028812711729522848000101500315412126279800153068513370010667233530004730
SP228Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;veroralis400000044400000738008023015360000049004012000060800003806500054906100001000000000000000000061400007000004500620000000002002002200033000006006817000000000000040000026998000510000124900000640000026700404102151800000790030060008073000000130700074330174000000000000000000000019530000000002110073600000000000000062180012000001353233190000000000000300000017301300131139600001965000002000000210016076014000000920000000000100000000000000000000000000000000000000006000000000000000000000000000000000000000004000000000000000001430000000000000000008600000300000017400160900900000050000700000000000002000000000000000000000000000000000000000000000023000000000000000000000000003020000000000000004470000006700040000000
SP23Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Porphyromonadaceae;Porphyromonas;catoniae15153028821808862247472082160001110112131111057267120151254290329757148141900765037277313787176271298289043753900663190822416574201185227112361155672258145081718263290315101608015048822702167538123394526725964552698792801254258767563342067757145784257103746525030105714319472927189431602281639310012142080721003310398152100760026868065114415421069217185125012102390332870191652517192014426212632516352417356315303002918881090182224423140331015618401552490891580767856031024342024777933741555154661095757782040174624255173381817332731030394273157807513936157814367418212743330159516240329412961991421004061791332901241071339770240837323563003414213532117536348403092094640185150466763116960629886033652453299636541681771557902056031954401428754566334049091271829386039432218935677561872713490383551961039339188032516396019817032002992314151812291052845801901127193481245148742866516040649431861202114496762644410470345180323479799426272619911110804855987762751100558833146104016192610511138244097166181001900493123417079020953218349725591093039601089325339405510110033013774038971430610300952720115414918535191600147786809011110460085063483702193143104569044683542390100640003950533726107279600114516320002313584456678535832759950095549971844027619411255699125171623980416223510440027502830015682819870119703361426
SP232Bacteria;Spirochaetes;Spirochaetia;Spirochaetales;Treponemataceae;Treponema;socranskii1600000320000040000000000005060000000011010030000600000362040001062000041215030025000000067704060063574001709181400000000000004200040001414500000070300000000001631900000000000000000000000401320060860000030000000080040000060000001552005054000300000000000001830340700040002000000157000060600000035600001006060000060018200000000060192003070080014000104900064250792082110240000153005113000174051015232400030011000003100164725202601415048002120059400023094144034142730205138190020180321390610926223069000001602101502741643725040470000220406501300000154283304101530019017400074700000124061822130000005900401700065220003482974000504515000001003070169064030000000030160000057632200151979000010700006000000071240000005830020012101452130159000001942059044000085187002320000000
SP234Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;salivarius26611402644105144398540705717852057657337705014891193378395782136120886010106016163127214112628027652023575933233322203589574667773778244214282462416821554615134659491873528113199230156332268826702558142403027428540046810130752427752293699905863848058691038321702128275206539120111091591815441378052409054724413618001160611978104241064038236923793127592304961513839489756091352262716221444124126554152324538473791441036361457513739368062321512028428504621030014741634307149369887340253718337224314441115064382136391888069052702472105545401965381602986144447841063135717421105539146035893071065486235839712045483179713071682255091325100011282136686641260155084444148406447896387775784894849136856469816745524545312095211610226373418763500182451240953618519413432574487864545217523373929269904210151529361162871362678929131254871110111355892850425894616664382333391711904490237376984126031633203838692692105178629643361105121094242724926466702242122666300250293453196122541808375937455350467678853454226335168715493610730164397836936363134422035562021578249011410634204483211829491542542116832444792517169544743340991124322367354724581108819724536049123494190227426511806461574041260764696128947243429195321605385257033295826365341007849202258604731955290166478902548122067000670703420018013343901423290023613000380500000000030239024603279018590452045996450003107040011001116020052177120007120000171801900334002446140105130060270118110070001600000000051044112007110201584815052578036001216601393232104111970420141103600161406417001290000258911005001902840381234114516420480000001102100132070011036001006300540671534721033121046114504470014000729214170000012421210800921009011100245791310450080013033119
SP236Bacteria;Firmicutes;Clostridia;Eubacteriales;Lachnospiraceae;Oribacterium;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
SP24Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Leptotrichiaceae;Leptotrichia;sp. HMT4174172668787133344016731702126316935040143940885195552955086326608711415775046989013593732212919046390284113250839218262184574819018416206138195512445249105107819574180678494785903131793997360660310190124402592682527603163430104032220012813236544766412012872466686474123253320601786892530564704256773854547526096832542356606651182341033889239241194837085007511073525632241258401002978116200003201717336034847601632120125840258101087835329217512782913054012516516251519186112460341483059419532983845916928202057243431439372173019732671933232612248435613457143156284120757000345017220328119303531432300253016756583723989103128583591518000360147818368360222139852304041647084319438536384717626327953017366818892941702223091012113429301114355278144283562190012051383361136452970513467823726016401664615312122631361572581151301450003802571270912203374218896896052495770763022844017000009236517644019623138105195147100004670104300627001392124103140016010015302820240075101771301800001217012765320300090615000000000002874300014785214139001324130402320005994200718002335411028395001300000000171882034000000010160000000000000371223192821217105129100299532194118058100083100000009931227000627000160036500706716619033021580960211861110064732008000000071191002020160237600007800001300013000051301320700000005000018079018810033090000018141710000000087008000800000000331305004901143060000290814
SP240Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;sp. HMT0616857378761356137249075200781523603441417338123700193000770109133331931137187150441083406562024313211264572472203364785799148421192669836317100143149630643144148910011003503421871280428740003061736191036280532807005434201792117416002912915421391641023110502959120421178103202470135041125861512136423300000941026988111176213080037348400034510229027766163840263342547394715500703653446283331587386001520011100365049562529043101143981570934629524037513011243763466331257895105006441901541642359619523167743091011247815217110202324601702472154616511391755261300673037161680221009498302521178518503430302609645722898190280036543005377663133857159702500172165860339829780009051900130012601440007000260000000600710000000260076000305061000710060000014004520000000000011000280000000000000000000000000009350000130000031000000000301833000000180400000000000000000000004500002209000015340000400700160000007300210000070204004550000000057051104880006000115000102013000000140004001000000091040000067006011000002200000028002112147000092300302000100080000000000000020000
SP241Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Tannerellaceae;Tannerella;serpentiformis19495000000813596448130000300051814988192366900110051180000000000016000002800084000590628027230006230000290509024173200001504550613601424940002960000300160280170002615021000450016110019001011660000000213070000902000001600000019001600005400314301121261631120000050018000000000110000017000000044712509000000110001343046216524000011063600000148530000100000860140004000700700011600316201900421800000000090016029013000000000521303540113227003639503700361050443503819000153800699013709425000054261000031001000033391110156480000614900277827100000220707013457816001370341350001144300706610298100025250000019027000000053534302122000054037905323112050002000002088160031042000000063001313420000137150000202041172100000014163052012302519400081461400000000000026400149800019900006722000004015300003201098004500000000230370000308290000002395208360012062000000000844008900000013000010218210061200
SP242Bacteria;Firmicutes;Negativicutes;Selenomonadales;Selenomonadaceae;Selenomonas;sp. HMT1490171004646822029591107040301626190518898180021130209121024204790035161504423000260029003761340632400565100520092000000013702914748260122851360002900000731425313901550000016100290194570211031025782371350070000204212010915003902140025902400386003324207241881701708412903109820000002300169516444323672693918185014002035136179103412481216801030177300005638011801000302701834725510999048288020073507285181431304301500501841717111280121000443015045674621301122000051112108262703871040211410404014100000000000000000000000000000000000000000000000000000000090000000001200000000040000000000000000000000060000000000000000000000000000000000000000000000007200014000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007000000000000000000000000000000000000000000000120000320
SP243Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Fusobacteriaceae;Fusobacterium;canifelinum0000000000000000000000000001900000000320000000133200000000000600000000601601700000000000006000000000000111000000000000016001400000000000000000000000000000120000000000000000000028000000000000110000040000000000000000043000000000000000000804500019000000000000000000000100250000000000000000000010000070000000002808000000000000140000000000000000000000000000000207000000060000042480000000000110011000000002232210000005831007034700000000000017400000110000010460000000000000070028700140066022666000190000000000000005600000000000000000000306000000000000000000000000120000000000000260000000004400000025701080001470000000000500190000003200000000000000000000000043600180017001712000000355003000000000080700000000000
SP246Bacteria;Firmicutes;Tissierellia;Tissierellales;Peptoniphilaceae;Parvimonas;sp. HMT110043233050000420159401391139432400164508121774084411017201283165111411000022010729006000001402002600700004602950000744404000002258000011730002334000000214301011522001701436001300919025630033200912706058450000000001701410160250020051853144443175800016090151313001761473149546691041487600002501066001200430500164000000740117102800331400000100003000012030001847060001300918058370012101319044008030033186000000681462153013283016003300634000180000001311761005042263319000029000020000202570001800280007018000050000050000000490071002100002280043009009000006300000110000000000000000150310000000200004012200000997003402100006805060000000001106110113200035163000701500020200160030000000000000000000095000000080041615907000243300000700000100000860000000000004006000141290702089000000000001647204019862000001000320
SP25Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;oralis_subsp._dentisani_clade_058423550571280140034111159328240110101019134101150109675143539855141362170475253581378131416045790316476901781380952543269466800340409177021701000959463171521179013462071572047547400085118230822104879706778809057142385226002472944545278262911200003580400022966225135934842585701103115691125966477240176557616003363931717328772141138164278149458034937122149536089746274447190445700073000002738033227008219653001852106621027353123715716317167653021135730141172405271803991520219015569000000274290632476105751026110822241010200693105538384323400837221052095262239377152392001903310031626639084037236042048167840000151580110480113181420406685119010421331601313415920044749627437043884016161860332707612961266446112285059707614500001000011756619804567584110681800132930164122010070627597154014911556261802880605506405164430035021371223575544890886007009500172031690000047281410299262632526314441331512717928004932720125834417230000182700006016115090061747141638140220127681750154700117404803325007823070820672513255437305770479017830200970170004016263169142871610308800091362278047600205047126172101529702923656104830108019610001500405456402760058860120059622134000005844562202516018104017339716000142205300380511741691480001070187233100075611268022286283040845014820502743300445569407726226121760210168161781536487120024
SP250Bacteria;Firmicutes;Negativicutes;Selenomonadales;Selenomonadaceae;Selenomonas;infelix0000000001361421000077021013000022000000046000050701600400123000000800600017004000000000080500008000016000230017610000060003100014000150000400000000701500000000103373500000070004400002000016005012300050000060010000000011031000403020000242000005000000001900000000200000702000210009120000004000000052702200050000000000400000001112000000000903950300012012098400064600013266351295914429311251610222053202430012600004200790249010209501511310296100220060132143057000412103800701100083033019305242350801812331180164286600529020414028905650703980800201300137020412596805033000218570086000000520323626010881670191813255814000146137023140427405442623918229000501084000800577802801874301661420140200740345800003104600631443516000790144518000001510501100086561353000691400010000003602815900000620843109101800105271071901500664006039000005222530042827700050
SP251Bacteria;Saccharibacteria_(TM7);Saccharibacteria_(TM7)_[C-1];Saccharibacteria_(TM7)_[O-1];Saccharibacteria_(TM7)_[F-1];Saccharibacteria_(TM7)_[G-1];bacterium HMT86900004000000000000000000000400000000000000000000000064800000000195000701810300000000000050000005400000310000060000000000000000000000000000000000000000000000000000000000003000000000000001300300000000000300013000000003001045000000000960000000000400000003000000000000050000050000000003000000000000000000000000000000000000000000000000090720000000000000018000347000000000066001100000000026900079000000001723640327200000005443000160003810420000043900000290000047000000000000000000000000000000000000000000000000010500000002951050000000000000000012040900000000000590000000003500020000000006020250000200053610000000000000000000000000000000000000000000000000000000000000000000000000000000000
SP252Bacteria;Saccharibacteria_(TM7);Saccharibacteria_(TM7)_[C-1];Saccharibacteria_(TM7)_[O-1];Saccharibacteria_(TM7)_[F-1];Saccharibacteria_(TM7)_[G-8];bacterium HMT955000000000000000000018000000002300000012000001205000000000000004200000000000000700300000000450000070000000000000000000000003170001700000000046500000000000000000001501000000000000000000000060000600090000000000000500000000000000451100000000000000000000030000013000000000000000000000000000000016000110000000002136000000000000000000015026000000240000000000000052000034200063500000023900000353305800000000000072250000000000000004130490096000289826000001600001020000000000000000000089000370400650001111380000000000000000000420026000000085760900000000000000002070001000000000000001242900370000000000010300007400000000007250990000150006461790000000000000000000000000000001882054033000054000655140000000000000000000016300
SP254Bacteria;Actinobacteria;Actinomycetia;Corynebacteriales;Corynebacteriaceae;Corynebacterium;argentoratense01940000015674441000000000000000000000000525045320000000043100000000000076166200043900000000000642000013610000000039000000000002100000000000000000220000000001462175600000000000000000000000000000008500000270819133206000000000000000000000010038640000001803300000000000011100000000000000001850802000800000000002310000000000000000000000000002500002150000550000000003000000000000040000000000000000000000000000000000000000040000000000000000000000220003000000000003000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SP255Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Leptotrichiaceae;Leptotrichia;sp. HMT498000000001200000000015000002000000000013030000000000005700000001400719600000000000000000000000001280078000106000960013350000000002106001000149000060000000000000160112000000900040000000000000000000160116000600000000800015000000000000000000000050000000000000000000050000000100040000000000005329000000000700000009200000000007000000002500900001922000000000680011000160000000002100000000001503380220000000000000120000000080334200000000000127000048000000600519001683000116100013213001422899800000000046900004820061200085000000000000000054591500002729300061000000890000002600000420701848011200000000560001303000000000000390070000020000000000000000000000000011300613000000000000001162111000000000007400179002421100820000000000000000111000007461500023970
SP257Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Leptotrichiaceae;Leptotrichia;sp. HMT212371413615412233442695710772345155490104701724394771472043060260314162588542163143112410740806645023191815383216727412568540124810111448031849441641525600163862706682100223497233191132324410892204723415913101260740199158238658392118110125508763983063108245223034791155282140301761481141311031079001900064211120210002902053030433778301442330071311919113904561012922003086010500424311272901722001132556481306146101223507009590035252105127302212091041551375925253404744120033431146115923398148380700167814603366157481017000311852341082012167337413425109692150217818443524526924972507028991176616396922347350182587303704226552443513320942435537531763618775715893241307309474211987402815644601675954345488586508970145156334250197885768111880634411616205159743212110589652768587034134511610802328381006061365430330105262124075012935186619446530010234240612211250812924090158411741682124629928437131029897141211455431934134350489437123923861638692080115533480616088915032564832828712073137296513672231943114402512082781337307340374161749500057683771915591610405195691166412836020305849754713394514170233818012302176302115220120120801606920013551846285592330124544901049755340790185284914004854865853378813210957038903037774211347712357572492106191961474689451289263615373589582115495142162214023441123221815235270282891442696019500910200322502729116427172747642321
SP259Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Leptotrichiaceae;Pseudoleptotrichia;goodfellowii301902806033103088003008000005692816500014080004000000003017070712000003000038291009106000000000000100069114000220140702490815415937064214016400006002090320000006171130000107434204150002300000153021000446030171214600000000300032236522000443608206000070503000100001000000000016023018340000000544040480090500860130400400233376150101824060000780926700000000922247000462000110080164014042500990505331800100000200104000011100041400000110017000700000000617018000000000000500030005000162201500000080000009200700904917404223000700000000000030200000001441030000560000050001300001600716104421603003120000000045100536066350000050031100000000500043010000000143000000187004903200000018000000050460000001100000002407516000133000060000004109529000003241435000530870000040000000
SP26Bacteria;Firmicutes;Clostridia;Eubacteriales;Lachnospiraceae;Lachnoanaerobaculum;gingivalis41315260841304969002864105362216237588418805114119311321614335457004536635170197246488512601004103712180971311821330384181607292835420420291109239816349645211739082420591789015107487216852151151189632450266120391041436118582614183700001306520066595365471726114019085287163132448380163227153013513532213121313885611010446305403235551301405829242140026097068552968607101311481316778354501120801121367678940364132527116420312531318934624103952691141471902610602307712586253342438012166896139941511761256952510004418547185755766131455924189828520179222891068421010517461103360824564146656400000391521173568175561595681136885673801721121229014777113233122382384483112199922483562805812188131161080011001902041890119000228320220001802799394151723900559066616338603700001238298006420016029400001110248000780631492361240024700000007339006711982780137018400027600530000000043003676240258202000000001881190152821055000844300001180513632211000009503539114500900000762713320000000000140405701610800180015001223784007249238271229074700640870045026283540000006006001000130000000196506230012330158003765136170000110410000840000001200000012151300041600240000000007217217022000142901000290000150800200
SP260Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;cristatus56001280006302061180000950001424543316476481501601676214282710460000000351635002698000000000027900000050043251030932090000078000000000019480028006940174400000040000000000356011200000000000197598151320244755380001331027600018740000570022084028400000001530005420226326120819307000959111344202000000014689300191380000000000232046000050031142603025301200005786049000000000000230655591170000000000000000075457189000000000023582330821414167512000005501400571100002300230000043430200003010000120672012614565032000294232213623000000048546880012284000000000074000042006200015201200156000021500000000000177900071891081681252030000001600000000020416305247000000000188028562150000012626170000072000000000000000000032900002870108628197307000035142225000000000136559640036125000000000000000400000033500000000082710000000000016000066471877800000000000000000317360000000000052450070000389000087120000
SP263Bacteria;Bacteroidetes;Flavobacteriia;Flavobacteriales;Flavobacteriaceae;Capnocytophaga;ochracea0000000000000000000000000000000000000000009000000000000000023000000000000000000000000000000000000000000000000000000000000001050000000771000000000000000000000000000000000000000000000000000001800000000000000000000000000000160000000000000000000600000060000000000000000000000000000000000000400000000231900000000000000000190000000000000030000000130990000012500590000000000003000000000001100000813026701101700000000000040000490000000000003500000000000000000000000039000027650135968110250050090000000081482062900000002000000000000002839000012283622063000000004600000000000000038000003601801000000000000000023000620010000000003100000000000000000000000020131700461600001184215301681710000000000064921560001500
SP264Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;sp. HMT9420000800000003350000037530710039231470003000000000518060000010510000000001037060000000011027000970003030090025430365003029000250000000000800170000823100001000282306043700000016523862721410030835000008000000000040000602500024400022200000000000570000000160006000000000700000019103800087000000000000600001100701330002018150000000044003420001600000000001320400000001600044000003000000000000000000000007000000000000000000000000000000000000000000000000000100000000000000000000000000800000000000000000000000002003000000000000000305000000130000000000000000110000000000000000000000000000000000000000000000000000000000000000000000000000000000000040000000000000000000000000000000000000000000000000000110
SP266Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Peptidiphaga;gingivicola235600000000240000043200000000000000720000700000002230033000500013040000300000080401600061504206014405000108020002070019028052615192960000500290097005110384001004000000051410652750316002900072000000000200000000966000452000007000000000000120000430018030000120000000000120001240003360800370010000000016000000001611175200075011001800013007000000000000082003028000190070130200441275600531606002614842710000005682497037127159390011086001000017269327680101217022036300050231700128006026000037524418429110001903177162531604509521543002168933001088185120233012004229131867029020100315109000448798913436140010214141371002200025145621125214981400084001372930098000037070560177000000025189740241709670000196000000034090030000166200044440012005100000032467300740001930382150136001870005890800032130811406302400913537639250930001570022610100612100032610842280072000067160408030130300
SP267Bacteria;Firmicutes;Clostridia;Eubacteriales;Lachnospiraceae;Lachnospiraceae_[G-2];bacterium HMT0960007010134680018060651610543541300015494069715148299320154207056016213300032100006871800000167152530140110000125572612377112420721488670000000001643312660000001641837176000753048262100631660029400001609001501380200015314386231831001282150000310090300650012800034003200285353010211301000072000000202224000020843192617096562000179004738718191004113099384233693000290000297000003867116092373800922771932455513000223187000000060261235416300000001316000001332142310038001640000197002106609709541853902251101572900003010310006900451870012000273001980051003690001000000000000060109372000002220002180000000190000000012000008500000007640000440000000000000012000000000000060000020500018110000900003000000000090000000000000000000000057000000001200000000000000000000000000010003000000000000000000000000700000004000000000000000000000000000000000000000000000010000000000299000000000000000000000000000000013000000
SP268Bacteria;Proteobacteria;Betaproteobacteria;Neisseriales;Neisseriaceae;Neisseria;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
SP269Bacteria;Gracilibacteria_(GN02);Gracilibacteria_(GN02)_[C-1];Gracilibacteria_(GN02)_[O-1];Gracilibacteria_(GN02)_[F-1];Gracilibacteria_(GN02)_[G-1];bacterium HMT8720000060020271188445033029040404102003000000000700002220257424001603160084001160010104214001072203504049727071150014250005211200014250019068223687500602326410014012001506304121511300500700001310060300190002100000001302900002100008180230200760534153000203308201719000017007200002500046000726030075030000010580130181683003112120000007002600637200200101386702009002700604191000030000352201150124912200590200001018702667602920831300672400029176449107101400961992460024400114343501819912702981144900277987125051193400050211433281120061111166112200051501387108843201140039510500052139221000331030091046689222923039326136706002159100150204792214535200381144900002061122226351361750020605000491202350479309142542519272474011000440005410600446159000003033203389412221973190012000986230219066046414643710110000143844005001804123816403231021567321180144894004110000531190020801640160141071481712501625761490003011610037247000001022100030212090021916190006500
SP27Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Schaalia;sp. HMT178883901401120015800010574000020070045200210220140000000002980131580000000124100852000239300000190000300000000001200190020571521504300000212325014202420010006024300070011000000000000444000174000446576000172316000081072600101937070054370300120310430000000400300000000150130000004171700000500000000000001400002090200000000500090802909024003400000110005000531500000000900030022821800000217714410171942510971101281500516414910818912100502304017500021311442813913929938645701321210179000232160553425311616188460122444125716212711701684386000110907124180086500504980660203251381245427101287780202331518344197104113513710891866332583950031520250110656158100670104260123144031172201704054004290000000724975930334771113150390370112741286154013974308219910000102472531040002120147706160843820612104135836492176030101212900061581201074082317000013131600327082400032110002066477850011014204867046253306866550119142335140600039067580031404202023181730401207253829122352322300001457815970053400000071144671149117605402606790
SP273Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Leptotrichiaceae;Leptotrichia;sp. HMT2180000000000000000000000003900000000000124460000000000000000000000000000000000000000000000000004951562000000000000000000000000000000153600000000000000000000000000278700000000000000000000000000000000019000000000001342480000000000000000000000000000000000000000000000000003310800000000000000663000000000000000286000000000000000000000000001010000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009000000000000000000000000000000130000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011000000000000000000000000000000000000000000000000000
SP274Bacteria;Proteobacteria;Gammaproteobacteria;Pasteurellales;Pasteurellaceae;Haemophilus;sputorum1207360195109100460280603329727462315839035500404019415556184010204401033590049220264242901590016114042124701547791267996189263154591300633523602712156704171074405835937401074312359014217820249122246674023520117942118326284055360261941809106496652817323115481137886142159043491770241310003204193343991851121631091679838661150000136618387034845012814010453612200026404318523933221887008316414336531375300015068515707160985520161001525502270005123453010583967215125042020023002802624073981820113180048856602001276873139295314478140405775036142101542005217958002130371095915415431407021944311107126437024325044006940527051616072100842109549847602600960600800000000000000000000000000000000000050000000000000000000000000000000000140001000000000000040000000000015600000000110000000029100000000000000200000000000000000000000000500000000000000000006080000000000000004000000110000000000000000000000060000500000000400000001050000000000000000000000002200000000000000701300000000000000000000
SP276Bacteria;Bacteroidetes;Flavobacteriia;Flavobacteriales;Weeksellaceae;Cloacibacterium;sp. HMT206291370228023000032124220000110570005190096407501158231368810663730048246000009900001391640076715923902330001590000081201200338621822089860101271949000370395191193401460659930028516610089017043610455235000002924007800033851101943712853676670046151314490000490036870138719965500981590130720020000000795200001500041300000089006811120121723850163610000042000049800012420900215000001250000001647700029342280085320146031000012021935000377170428043261300001451250017009082313005301470184270172031948500113107316500000001526209091251207190266014401420000000000000000000000000050000000400000000000000000000005000000000000000000050000000000000350000000000300000000000000000000002500000000400000000000000000000000000000000000000000000000000000000000000000000000010000000000000000000000000000000000800000000000000000030000000000000000000000000000000000180000000000500000000
SP277Bacteria;Proteobacteria;Betaproteobacteria;Neisseriales;Neisseriaceae;Neisseria;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
SP279Bacteria;Bacteroidetes;Flavobacteriia;Flavobacteriales;Flavobacteriaceae;Capnocytophaga;sp. 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
SP28Bacteria;Proteobacteria;Gammaproteobacteria;Pasteurellales;Pasteurellaceae;Haemophilus;parainfluenzae37751208870223824753517214220892474782601153940551058408219463815716771611140257415552906228033015339219711532836245530431804899294016743947810158627183232363518712976118511982981337716893004289139763744207711565440927442616311449972688660372023743824342657338189578923657722652414023952253124271309427752206257380749571733668058511295121570847422241283871476981695398938861127266412981838311492112511232425828044985560213021767417410651478738667013935449269719452619385328672099249920818527794521156918402016756228553979515337511475376557588925108187454991815240821712368135380024621721040181833803075411110799472986327523231333322119744811025832579142760226031198442030452693545135133964792249653261764958178332092461896322168212992159165740021432383520812574072185327227929414500178058983471531910337232013531738305812371839367330393685455832345281250359918154032602529162025007693159224721271827235885883063446202388495429291555507216227093708691369823206502177255426892214111711011127447218533388974290545526606495416782021783406479011356161430646652004315340123932868306226461403282411721733322517062364313333609992901519804082446622831393445165344595621470106121742095111361522640454743651727154635338713161828476802178108732944531778111222417056965312715119172193173451591959373812291305182676011143414211162467889610476371771743711270283351249573458184472827410961835402596862408327519437329213718272513226133993951723528554137962566744997324438161018138649144167102561228235761021069433220594983177263256762476477370310154365210881935629207319168436314218487491226773524115989585170209260419137862014584121277482762051320654650724271417501655301072955092502893254078626412593795613817727521035226725193082542700443562576128196309414417748382402391542344302223145349036225562335627994170563710622431849504647186266621034994968610881725150043744551515181901874510952166619025021216401915172679026028860301914032697165919371451028632483242363226621109316428182401420511621147118517685253908322428428981582201603859949334503181219346737581227634819451104117777450253975521405014687561080149474639
SP285Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Schaalia;meyeri000176002810000013167470079919000000000002720655523413225027280390008986000292000019005152760012530000140617509805920272770556007701400000222500195031901800010001850238700000290000517530000000000063089251120000000075503500001448021039073500019200271065000233231290016437000000000000020232143110075813580004408870160116940037634700317832652009900000007030110582044854464802554001552740000014500226012001100022013108060000018014194268541203000000000003550162429500000000320013000001110980830145400000000000000000000000000000000000000000000000000000000001100000000000000000000000000000000000000000000900000000000000000000000000000000000000000000000000000000000000000515000000001500000000000000000000000000000000000000054000000000000000000170000000000000000000000000000002005000000000000000000000000000000000000000012
SP286Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Leptotrichiaceae;Leptotrichia;wadei113329383316120198001501008338720600256838145400000000001010871100036000089111221700112101000210846000184000104900070194732010060000008001011019241861030020612513243148654022721613000075901100293208000009700011200014290000000025001412020019922115331800015351345100561770250203033931301724793812000090039038008454600201207007306711130038012001001500009000486000561106017490012202800000003900001579000792033112701044919000021502242007355000002222000000028209000000032029713415053828739680000160437035013790781383288143406008419261353225300000001000073894903903500107001180643314191000990007366622160025980000160800151061901797400009844004092454450500546550811124178028807210151526195037486332410578600000052610000128041400000114113900000000000000013300025994846210003000014840000250012413172341105860362482114323014015000670016251000122197011323001200241893111606151700003600002830005904000000372600002200059002560342260022007050060003311120837661360000000107100050567000006001430000143083000000000190002706053322700032790
SP288Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;sp. HMT056552957004021170460720000286416000821008000040000000006414023620000001600010000025600000419000000007000000000000186800000010009061106243711420021640000002515005110900500300001193759000412904017001601020000003040157000004058000041500106000770000000729000112807002002730622005103359001309351100001400400024000700008750000802484013601501016000909300000000002400130000000551231620084922130000464240445310700553201100004000281716401813209000340000024200000022100431101912300250719121300110108234000300131580060010200000000000009321048014027940023010716655410110596133830023007027679140247800170040000374360100015819000022101987361374040140010200156871100691716120000561300679000102108224001230030260023100024203002860354501802873411850043025426214003003830802503300003040000331601850150865720002680350242016310254650202453704201100111913001783212400001010409000246024204004168
SP289Bacteria;Gracilibacteria_(GN02);Gracilibacteria_(GN02)_[C-2];Gracilibacteria_(GN02)_[O-2];Gracilibacteria_(GN02)_[F-2];Gracilibacteria_(GN02)_[G-2];bacterium HMT8730006000000025200000001300102017200000000010003900000000006015500000130502400070000020000000220000000000000001400040300000012052905070000030243752100491458004000000000040020000060300002300000010060000000000000000000005002300000000417030000000000014000000000500000000003000000000000000000300000800000000000000800000000610000000000090900640021035060000000000066180000003007220142000000000290013030000000000035290000003000000000000400000235300000000540000000026200000000800139003033300000132422921501753430074002000030080190700000900027836110000036320030000008300200000000000005700000000024009000000000510000000002000000012020700000307000000009000000020006300000000005220063014230001900000000900002000003033
SP29Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Actinomyces;massiliensis103499429031051292528050002491019101400091180719173139001318078162760624212115134086901013802437725801831153644363185001210500438250700230281505598341095187350056121174410144111445767351213012418314022042065349043193506118117016016334544918166913000079618024151574440018016240012219464142861279881832561713109506054190915060029191020159754131415410425012918221820473234696120004074700003807705720362612414240037155937192111191704114281300131082801505210007304928187231211700161383985412620014171101089492111099573087913247208401155100015941479431493311791292270211662473418510361696221817269214510501061221737176690172110809361066583548406165589788340280032420782101854128115320341048900798302676510847671523399057229493393488543312132571953268172511315486741120481296992011339594263262863561087115569426227122359849383155692117181339917813164233269167832001255118869191576223364640609146776924478544486815039932734672359761485195182341071104955658171920182092651373511727745071992117362046109933596108110395973311751081105116848624114982344913056853318507995256782691329233855042561398531312352011948591384165061254919051374358171498418357751661086222763420864010591115785167835722482187325993083261457144212895288740879554032251225389501167199132207402771071739161615012011125733154435329467042633546410511091356567864361125313162528725281031601234178191261821063994696442642744430251320192163152931999191874151986961246252130757877200931614681927712712732441034515582191023733148
SP290Bacteria;Firmicutes;Clostridia;Eubacteriales;Peptostreptococcaceae;Peptostreptococcaceae_[G-9];[Eubacterium]_brachy1935460140003737342004120007018071990100003028420263000425600420255620060980000316213706720140330407332320730901119121303001144191470290000035701414000170110113329514000902000095700220014211507200500300520070001906141941100900316133906150100444005870306400023833003002814021211133000006336023004870433003615140021302221615420000152386862030000064780008015412025041003108012000804005400962500501190480240805000000423200130029007012000000000000700000000180000000001500002000011200330029000350009011004200071120003503050660773402600000000003300610040000000200000000001640100000000000400000000000700000000111500080400000004001700000200090000000000000000000500400000002403000013000050000000000010010000000000000030190000000200000010013004372000002003200
SP291Bacteria;Firmicutes;Clostridia;Eubacteriales;Ruminococcaceae;Ruminococcaceae_[G-2];bacterium HMT085780710511001410527579525413021491178135642359116312635120106148734244231447292080733244263959723154834558101251392331922312972830412102565292132308922044218100063405910895719314966950921242619305258019123422698133300012535110291449214561271928336125125426601716611275002553065583051893415286570626822528630292611821091340101012644203815103218181964138195157741181774251600892895100351683883802715112305311727713117401506427483749166738932736515413014186070351461612636138101026159182430464038101183287576366016876407919650682291093138114019796586720404961222639022711962340040106023112982019461311118302521741951130527434130001111000024144114232377301042055088114600000630000052008400000010520000800007000020001500000033000021633603400042182600126015603000060046000008001200013228461013817500900081189500394000651700783500037023300014921000005502085000003308302170000519000000082015000000000000000020410090000000000030000600820000300000420000150201500300300000000651240007918749640000000089023000000600000000900
SP295Bacteria;Firmicutes;Clostridia;Eubacteriales;Lachnospiraceae;Lachnospiraceae_[G-2];bacterium HMT088000000000000000000000000000000000000000000000000000000000011000000001480002631000000000000060000000000000000000000000002200000073264600000062400007700000001800000000340000000000000012000000000000080000000000000000000900000000000000000000000000000000000000000000000000000000000000000000000000011070000000000000000001100000000000150000007390000003300001300000019632280030000000000000000015006400000000000000000000016100000000000002492900046150000000112100006401831600000150660000448217242013621060100400289818266000047006800000000101000000795900000033000000000009012400600000000000000050000000000000000018000000000930000000000600000081045000000016000060004000002101960000180230077401338800430100000000013000000007200
SP3Bacteria;Firmicutes;Clostridia;Eubacteriales;Lachnospiraceae;Lachnoanaerobaculum;orale0158594111573748518121330448275026364021177130298014521800387085552011038386032502622450181813367624160003428000011131046894046313317462365062836070300028106590580330121109828515019351603145261313430803992101580010170463543619415511900477043076130027878018849000010303720867029027582500023475102745502042104327002159817328846143410018250109034348552141684331402081043736386713814117911800116111626310861151695613264128550014026622540040202803563572531120313587259241281137206311170000387198043471222063404148508313501983253703024719730136090121110001437056178175111140713261601110306340981377110761780013610840161446206047194100111464823614202311731614026115210272433865243490000041400005296023000000224000241900700000000001716000011012000000188025293510000000000000100025000100000000000000002579000000000250000000000000120001509000001441000050830001300012013000000000000000002501600000001000060000317000011010130130000000000000000336000000000005170000000000000000000000000000000001300000000000140010000000000087750000250110000170220015000000
SP301Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Actinomyces;johnsonii12601128001332472942016241348715036010558000180045314013002506500446711516620103730702061037253494106070003400593000030011230543500894140602332511281421041761024332001399501130471003380936380003000120704116185551476130170121707450006810110914880019231016519035402120008218401420520600077192181054027403209014145355501109010007010006000410934160851702010000062440444162010005112001501120232711011100106410041500601700215015115157018016757032261011319530121225598772826832293118822576123899241475103883147086101233223200132017446150153616601087908627141531561446291885490215161114731601155219101277804901490118830040802369841778530835635565017977701165974925116439216410804291226043481016005393662533193103480487482900040740205172904621428109853127669580212944427223041032528027222003015728184065414737673373532204371777523101070336444031448318273414601791899123239271920886610665364180286511426035420899315281150336801804513834894536244330125019521488381941423110123882239736910150400122742694169177764421244751883457962871841442817389828143750870470277052553445762118700012205580401240744123186399511875606872943530975480018104617972633226132543446144372774023317341
SP302Bacteria;Proteobacteria;Betaproteobacteria;Neisseriales;Neisseriaceae;Neisseria;sicca022920333000006450277632521214420000004340260398522411313037009471600000000630680197021202051236090700045031900076902026001811996279100117404000000064610831000094074127061000018892127292680114001443000304043000109510002526228011378700008800000000000678000070211384818220312910160152000000015091634538840830082000501235122160016035587592000009532601370185521050243011157809930000610036800128800131165181000033547000000240640000309857671200001040279247515055177028600358000940198000024002490764960350000017000011380000003700205910522490179761002160002710940800000117238437073797971018600480791806630295309253411051950169910400000000843322982520142901403247205710005439500094802390000360229511700272240000000519936631000046900428000000121113332688810432902871000117904400038248000261468978807920480000000015000000738800003332486690721641055510161096900000002408921743775180465000019000488934731780054320115661540000017842630354051022373029670101243601223000052002562002644003622314250004012980000000002349000019224955345154400001420279091779500002620069200019201494000000032170186385097000000000910000000125004194608161079235224703429700
SP305Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;oralis_subsp._tigurinus_clade_07100000000080012407600040000000007000000000310000000151000000106412401442220000000085550100000000000820000001603141601800017422095957034163212000000252000008901700046026000001153800000000040035960062142000000000000005009139909000780000016135000007020204700000003700000015033206825500050000443801800000000000000002732465120150011015010090501330218800000000000035033000112000556970682400000000097151423671328408000000000000000000001653180901229000000000000040000149940000000300000001381186149013369670000000083006900009260014002770000001065626380407001624047000017442236230000009000005705500000336000031234000000000004742515071874101600000000000000000017634530003190000011690000050110002072300000000000000020741805684000000000550380000051000054000008171551933073007902680418000384287816040000000000009003110002270310183031179000000000332075540630281525900000
SP31Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Leptotrichiaceae;Leptotrichia;hongkongensis01810491081701653268402470253914866919000143546272238130101518007130397101502214546282480175611520000003118829171419052527166035416502520330244120029121262000311313323356147151815501691917202413700902371001945655149882450409034163512453560158814642523210250080111037500901000701203101700009220225423610302040585840603590260040301800000105800712047113037329303022000275643000043007140042607948195100220501101949141720029100000039157100169200120440226404216467163115033020332668696320710381202435566549160028074129160748723107021515472791673426346575224231319927505030793219543962068436798650361161112042325597235240462470292279726503002027006638540626411597240220678243268330126120028331160581962018431255301252699207602197665207859317568770939621230700140482455698142407234108190446104753039771751218821176641133012901662530444501444950030137112101232663010755051324640262100642000161430010662864721473882824101926117823162928701313201140118620100643172000012871500006254898005010574039912200446573764000817130013011222109332218536698204580113000843175505336548036100267231270002633103910025741166230816220602020091477286364039961378
SP310Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;scopos4005600005802300621963059190306000000000008000010735000000000000340000000000000100000250000055183220022011406206017001530000428700047520176250020005931325178400000001390001930000001301200000021680221300000101400290000000510000411612858007600000000000000002420000000000000310000000000000110420019600000212087008401050180002000118000083000002640683700123000408079224116060000017000020000000590120000005240801041000110880000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SP313Bacteria;Proteobacteria;Betaproteobacteria;Neisseriales;Neisseriaceae;Neisseria;cinerea154174002900012802168360009186170051421121977230159212919017937550534657818540680391631160113155122435685144004203557680000001230691243214813111221012281301411871030078128011016110465990198000120329991402771641557538600286125111192790146031515900725216600009034212749184670106297013116011238002839011000000007342000130500305808221130750071252809026100120026200091132700534000196300000244123998101000014013105002285300077031000033137899040471017180000914976271110885027122124331100002036000424418000036044540251488016122600300040004000000000000000830001200508000070030602700001400846013000180000000000001400000018000501020001700000000030000001107006600040000700000002600000000000900000100000000060000050000000030800000000000011100000000000000000000000000000000000000047900000090019000000000000000015000000042000000386800120005000000000000000000500000000000000
SP32Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Peptidiphaga;sp. HMT183510055000094250002030500001604301401700038023000431058000120104201200000019203001711734824053170017210642216000003110135012284330403304241510009016904773057702906126000401200752761130000100015832120300210658229190022000017000718170000100025040065020000771016094100733840036025000000000034155310255331201943461016240131571940000000631161314400104343914140050310097311044804028026000413002717308173700019016524221050047201587610180020000227193700040004001600111701200190228906012135006060028460195300000042282070000000000894500830842600600120054168214094001523114180109000050521838000400019232942860965338004800000371603343850112959636880000156810022163900411988000003612106623300090598115341093024388800000001912200115102600000040904008020703040000901302420200000120301612150000000002400818190000007401025810005182629000030002247201000003621230156000000019083227003820066329200000113000115277540439132700001860286332512300906342285010800
SP320Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;sp. HMT074284001796113136415391330181096021115521017436714359200760000000131742724160140235012613540181845551963160670390412015218211814401235991743063931008323214560012800121019903890350471103571160001530376149332194405051800142490633111547320335740245697404444001013611452800001500894937620494000002960134236390311849008316223793845009211996227577424811529310171499017106238105622496153975647000000020136217169024425023415001515122610736160452340010554275334013247851810881310005349313701100020044013015941804266223821510541860051200113170142439519928470010327864858818274113376106880665024911192261331472460000151001907424129033142500003305663340357428095596546577644127003272000000020000000000000000000000300000000000000000000000000500010000000000000400000002000000000300500000000000000000000000440000000000000000004503000000000000000000000000000000005000000000000000000016000000000000000038000000000000000000000000000200070000000347000000000000080000000004000000600001800000000080000002000000000
SP328Bacteria;Actinobacteria;Actinomycetia;Propionibacteriales;Propionibacteriaceae;Propionibacteriaceae_[G-1];bacterium HMT9150000000000001304700000000000000000000000000000000005000000000000000000060000000000000000000000000000000000000039500000000000000000000000000000000000500000000004708000000000000430980000000000000000000000000000000000000000000000000000006000000000000000000000000000000000000000200000000000000000000000000000000005000000000022040000874024000046061000000000000000000000000000000000000000000000000000000400000000000000000000000000000000000000235174500000000000000000000000000000000000000000005509100000037001240000117015400000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014236000000000000000000000000000000000000000000005800
SP329Bacteria;Gracilibacteria_(GN02);Gracilibacteria_(GN02)_[C-1];Gracilibacteria_(GN02)_[O-1];Gracilibacteria_(GN02)_[F-1];Gracilibacteria_(GN02)_[G-1];bacterium HMT87116618003000000000000000000000800000000000003000000011011000000000000000000120000000000000000000300000000006311000000000000000000000000000000000000000000000005040732001019009020000000000003512000600000000000000000000000004900000000000000000000000000000000000000000000000120000606000000000000000000000000000000000000000000002591304500083266001170100000000021651701000005163900000000000003900000000042600000000000000000000000000000000000000701130000010211007424316530280000000000000000000035000000000000000000000096541007000973950013400000000002679003000184210500000000000004900000000040100006400000000000004000000000000000000000440000002330942291140080000000000000000000090000000000000000000007375113040000
SP33Bacteria;Firmicutes;Bacilli;Bacillales;Gemellaceae;Gemella;haemolysans37942617616721113032005822412945631012327125299465370658548232916841118461724841183208971211002739574344891792521118635819259669828773181326635718111184257275551542424332713803653351025744146512519376547716468762307818047112821584125055422033051943833439950510483123619272442271605191795156222237575380713811786152313135203567828172326311167731386216914651759115058219021036135713265921153161641801277221222362451914262335172377111614459471701272119107262252677882112911218342128116421335279634363692361929246916395314337521222320747816423872957211416572866347013729237682591610795417227105719291132248946210513491164622691143235198649336931485155157126231231339155219147415641816549857250211633113058211652581381442100539755943616285301974644288164562624241170845108206574398141611509462111438234473172183301461694215601483157067889378275165496824770268628964333498611628802007632100883367117029061073550215515205628275225815111572591843506106149281701131347842097462180769677154113713881441565876445184768117240001113061012531317134733871020321608012591015238302013112626065010132502723828700766430403113151042882601144250140048730130696222031741090192100300641102870004844050470300179025164010011707029100190400211989112860353470149000170141027025060708674405915008104700054293084081430650112671149251038412384127380001325633460270601328709426102136410120314435503514100301224190068818268435189014020145102494008670000023727013723183001961910300210234154745161860066703301400214914622910920100013618294923000861021140330
SP339Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;intermedius2344149232251330132113115824031769274728491341594326403881433615557240539280221808241233615461431171011260184013819171011241935613051393205190703111009215329144892222255992118134027443602434426122076101070233628339797665530128119181467291624105442623017186008105512334010501395055107499413414631641220681344515705212123869148210380773810750491029223735561334252463302352016257201073401201209014619190892300004140109443851215742225919322117051172046381811162323124201027190457068912233248757119001110033516452132614526183474601739331114501200457198723549228042122114792602330672015042226251000423203232013540020000032006801377100432260080006800121900030000140500064606022004101300710525210000000022603020029000004062012105110000400751682511000233245023150333300330314100503090171000222341134408000003020001161723027260000000000002270400070000300030001000200000004600228000201602631500021502750000021924004055708000400018195166297000335070144900000
SP34Bacteria;Bacteroidetes;Flavobacteriia;Flavobacteriales;Flavobacteriaceae;Capnocytophaga;granulosa53590008009079141300000000900032244616463915000508000010140000906000116001100355701700803322901083024430131800000001191301100046009916290090288019730119125182126988100160002490140086000000490000000000160284101003044833233003339016001800185090025500041051031600551190720530015000011032400300000006263390000090036002602403200310261414142200150000586271616128011703400430140316015195844760112163417838040060044230160191700040003400000000003996333000255788294026554565631584873065419739113114010112013764266110814011192521630212915258706171280061182350301224741321173105282425249775430270409099013111418624716020648226767200250921271473010216877009067514310160346131727147031104741841331032188930300181498649010347543549237837240112469930176580170218156525873808602230893061249247202324691058002735100000934173171626352814741586262823818244514914874746242444242225640956901638125922110287651802305853214751534514003428117731802325811642274458395045619005702106012270302100108202271009027112750454243019796072113615445760310058134119291470496420586845235112897704490355002612103418443721923210902120201001787010501386702910157742872300387197210223610025574003390405949131004943104418157001912901471276270131717223187
SP343Bacteria;Saccharibacteria_(TM7);Saccharibacteria_(TM7)_[C-1];Saccharibacteria_(TM7)_[O-1];Saccharibacteria_(TM7)_[F-1];Saccharibacteria_(TM7)_[G-1];bacterium HMT346001406075000051770311234181600038301763501426001912500000013507001001791630115262000021913566501350122002800000151158003307100761930319302712300050000000870220085009419000980020133820880000028069180808000040122007030700004218101000910200106533010259000075701400330002281004001402911433064049001017410171101170300740000231713505715311011047224004203300503001000000220017000530168110440380261614071100000370500071902005200380054800184000157359270784135579213553432010043841117004046060026403360018270520000038113501674230052002910001157160003302925302600707000346721600089047839929563041834149001485380300105615307159780105287390000009006181003201616056700270641108003565950210123900000790362321316040750100000210001009003510000181187523424249730338636000692014190027773002920150000611310000001651300199024890006070013343715300001820069231253400007338411177400205939417655000804400000003040146980000000016520040214103438796530258500109464217911301705000002907000029594000076
SP344Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Actinomyces;sp. HMT4140000900000000163700000000000000009300000000000000000000000000700000014700000018000000020000000000000024600000000000000000000000000000000000500000000000000000000000000000220000000013387000000000000000020000000000000000000000000008000000600000000510000003000000000000000000000000000000000000000000000003000000000000000000000000000000007380000000010331514000000000000000025019800000000000000000000000000050000061900000030000000052000000000000005810000000000000000000000011100000000000000000000000000000000000000001119300000000810934000000000000000014891000000000000000000000000009332000001100000001442000000078200000000000000000000000000000000000000154000000000010000000000000000000000000
SP348Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;mutans042048100047022366000002470405730000000061300001803820003000000174403000400000007602305000000000300300000282740680047500038000185610530081000112400002404200000000500020000000000009602017084000000100261000901718000002630943448000000014240040400161320084020000042750400052070000334250000000001210002560000012470750011130010019779428138042000010000000400000200040001218000000000051022491845000160013670140000002554222000002320020560117700000000910000004000013100000000000000280091000000000000000000000000000026000028200000047877843105620120000000000006000000000000000000000000270000025000000100000000009036500000790001117093300000000069000080290000001200000440000000001540000400000000000000000000000100504006556200000096129195400000000000000000000000000000000000000175000000000000
SP352Bacteria;Saccharibacteria_(TM7);Saccharibacteria_(TM7)_[C-1];Saccharibacteria_(TM7)_[O-1];Saccharibacteria_(TM7)_[F-1];Saccharibacteria_(TM7)_[G-1];bacterium HMT348000330000776224770036260020341620000000700000014000000001525001500300134000024000271061780202210027029710000500000000000002824093308003225075160000003459130950000000390028001400211543900000000014241026770000540018030000000000000023130000264849000000000293426136640000180031752785000000175000041000000002730000000140000000000048770000021000027000793322500079017018099000251900000000031006932990000000005415444905318391562901800005405910203944639017410340441610115562684103820054704030007600975101521240071162948017317461396415262231198860167133250065409278490211625000933755162341911830050321000415207852761091020517512074556169549128263612151852700837140544292701831140134069599433650270025400811144001020215213804500497309424600167701068016800000211248610322224625139718200241654300127042515900430074033262165495100159313409070487014017000324317319550750109401930232827655211364204901622095037000037101511201301107711992201400143223939960000226001910282916471009381761409050000188021508330689370319288005800092813203409339520805558004300025175864137600237000000651051000441357432331191901480
SP356Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Fusobacteriaceae;Fusobacterium;sp. HMT24899700190000000000230280310032002017000000000000014000000151413422013415500004260001490310300000005402201140001581180001110010517447000000000293190000270000022225260010401040650000179041005100033284010000016302058600000021043180000001213000000000430000002600020600000000000008000000000300000410000000000000006364150000090400001323000000000000683370002201000000058000000000000000000001400000000000000000081400000700000000009080000800018100000000000000000002100091800000000033000000000000000000006900004500000000000000000000000000014000000260000460000000600000015080000000000800000000000000000390000000000120000000000000000000000000000000000000000000000000000000038000000000000000000000000000000002400000000000000000000000000000000000000090
SP358Bacteria;Actinobacteria;Actinomycetia;Propionibacteriales;Propionibacteriaceae;Arachnia;rubra000000000000000081011000000002100000000000000000005900000000017210000000140232200000000000320000000000000006500000011070000014401211300000060180000001090000005280000000100207500000000000000000004002800000000900000000000500000000000000000014900000041009000000000001100000000000000002100000553000000018011310000000000000004200000044600000008020120000000000000000000062613001570000000029843130000000071471870000000250000000000442014278200000007600000000000115428200400000000000774830000003930600000297031614000000401170021317501660000002776473011600000006401034452000000000000000000037000000000004363600000000119060000000020000000000163000000000000000000000011784800000000000033002750000001588000000086901290180000007001220136530355000000984122251000000029020271694000
SP359Bacteria;Firmicutes;Negativicutes;Veillonellales;Veillonellaceae;Dialister;invisus00050010400800275002847261753760184146149203376244001003110048812110133557040005781712120065004454002541350039021536150023817751700706540717001210434230190170320313737975015030040819191505071014008074000005000001914220347431140031925502842202922024609207000351403101620602474100007004400508504570610017103800019004213129330503224406161808404143017812951280000630300705211531633291231018101100022161000361161100000000000014207863009000150071200004000020200000000200000000350005000006700400001013800000005001600006802300053000005508116604000000000000014000041000039590000000005950200720000700000120000000012300900000210190052000300002720000000000000000000030000000000001003400000019406000027000030000000000000760000000050006004096201520000001386040000030803000077000000
SP36Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Leptotrichiaceae;Leptotrichia;trevisanii0023500680039708000000000001015800000033718026251480033500307240000051900004050010000040201761830230131100280071702800010264440700000601212004873234069060151000000000000580150010002442381004017425290900500070017207000000600005047000000160808180055020010013500000140000050110001400301230470170471000000018012000074015024000010024000100661201100813101091800000600040003066009087055106290600391082030022490130000208000028107150000000672651910239505466400000233200003540000005030001000715123702752054217172262468100600500001930032500009300300000140206350290050136080728000000417010700007003167346000357262142800801730800913105000000000001990880000140073063244471071490000089000000800000000000000076816020041242389002100000000000000000001300261200500512006400021133003500004039001100000700000001500080
SP360Bacteria;Proteobacteria;Betaproteobacteria;Burkholderiales;Burkholderiaceae;Paraburkholderia;fungorum0000000000000000000000000000000000000000000000000000000000000000000000000011348000000000000000000000000000000000005000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000300000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SP361Bacteria;Proteobacteria;Gammaproteobacteria;Pasteurellales;Pasteurellaceae;Aggregatibacter;paraphrophilus00243000000001400000000000000000000000000101400000000000000000000050000002200000000000001000000000000000000000000360000000000131110040000000011027300561771051000015520000000026000000000000000038000000000000000000000000003734000000017000000000000035000000000000000000037000000000000000000000000000000000000000000000000011500018374200001100000000048000000667000000000140000000000000000000000000014300000000000000000000000000003000000000000911500000000000000000000000570000000000474700000000002050610018114511225100001849000134000021200000000000000002110000000000000000000000000012320000000400000000000000000000000000000000100000000000000000000000001350000000000210000000000019511200112664120400007000000000120000
SP362Bacteria;Saccharibacteria_(TM7);Saccharibacteria_(TM7)_[C-1];Saccharibacteria_(TM7)_[O-1];Saccharibacteria_(TM7)_[F-1];Saccharibacteria_(TM7)_[G-1];bacterium HMT3470700003900102401546300090020916800000000000601200016154100000221300000712004709111000628810000000000000000030095300000951380025012190005019469200009012030000080002677110736090000000029301040410907322230070010012000000111101022221448000000700419190000000250310000000000000000520500001180000000000001470036000006140900110090701401511209406300000013030006800001301517191160000000001800520118303406011004212036143840080060443124243447111304647515143741326033600000015950955003940648479812616260001509114800880020719500261097776170017451021150000000010122400350442002861401113068006855713143078982188130335157013885811691530703012001250076502196929243698232830400610000412434330254914137652810117573148980132537063150452102300242428492323424574192664063100001660004826761400003706737839207809640110011000000325200451000000091100000008800001916900920630006516503005551594221470262150929301005570571133925434400024111380158003910610410340310904524201807700000037013979604391389473053189116330
SP363Bacteria;Bacteroidetes;Flavobacteriia;Flavobacteriales;Flavobacteriaceae;Capnocytophaga;sp. HMT8632110000000000012000000382900000504107000006002400080000005096700000016000000531100000000000000000000100000001010001003112000036082000000018000070004000847200011000000001117500023000000056000900000000023500002070000534002708900600090000084000000001497000000400040067000000000000005070059000000009000001831800002102000000002020003200000000790005050000003713300018500044001840001580039000000000003800003225550512013000004127305512515000000000332229200000010190000027008000000500007000000129900115000096000811393050000263000000005405001300105220005690062715210000000188000215320001130063000202001450000018105000000000380220247015008000360574700357000000001100000035130000001300000000000093850153051218000308000000001770188500006807400000016307600220004800610951008303791800000003000011467000000
SP37Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;pallens1049951791192072191214847979613521346927814757105607961651968340111294136657412196877811518542217327790601986157753141180152936606821467155665835346181882123318195856159450578888047256413848482812420754172233363133108841469603171577239235238523952143214932042442964638550526511152221122968626158686609044444820419989655718538029223661834153184143410055420322310591115751473133288380452124014754201017535773711953132132102773927421634837876230058718354648090257156934238119371558158399110377401416966234943030250273318325311013502538751532127983312611683303031053321279314708023933223209218137873661530568426618693114514992958810361021796709239182121703841521187520393452854689525139338521312302205139594365126914127081824151916018073384771725958374716424973197576341078039022735049013733180297659222744655885422744145926865253212739109245824873119837541081212813494971348763149623732004091675174412882521823726561374911159571011713123690258132477809013000001700141500150000168000205770001380040261066007000001002000000000001500610162001400001706000600000000900013200042000112000040000000600000000014880756600000083060309000225168601086172000008360008958700004002700500000000060000105160000103031150170000000000000000000001404090000000000000000000290000000302000000000300000003010000021001555000000803800000005069100091610000380
SP370Bacteria;Bacteroidetes;Flavobacteriia;Flavobacteriales;Flavobacteriaceae;Capnocytophaga;sp. HMT4120000000032000600000000000000000000000000000000000000000000400007000000600000000000000000000000000000000011000000000000000070000000000000000000000000000006000140000000000400003530000000000000000000000000000000000000900001500040000000300000000000000000000000000000000013000600000000000000000900000000000000000000000078900630000000102422100000328000000000680000000000000000000000000003900046763104507200000000000000000570000000000000000000002082210006000000000000014700000000000000000128000000000011927900000000000001694790002103300000000027100000300000000000000000000000000064003503570000000000000000022300000000000000000000012940000215000000000000182031000000000000000118000000000064141000000
SP371Bacteria;Firmicutes;Negativicutes;Selenomonadales;Selenomonadaceae;Selenomonas;sp. HMT9207100000000002004004000000000000000000700000010100000200000000000000260070000000000000000214000090000007030000000004000300015000000000000000000000000077100000000101000000000000190510020000000003000000000004000800300000500000000000002000000002000000000003725000000000090000100000029009000013000060000000000000000001654000030301012100000000036190394500006913076038000000000000004503882500000000800271259070000005000202000000200050041000213002069000000054701501138000000000000050039110080000011000000000010140003000000000000000036000260009000580000000002000000000181000005000000004900000000200000000000000350280008354200002600000000001626410000000000007435038131200000014011500000000112950000000000470
SP373Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Actinomyces;israelii0000000000000000000026300000190000000000000000000001000000000000000000000000000000000000000001206100000097600000220008000000002900000000000000000000000000000001570000000000000000000000000088600000230000000000000000000000000000000000000000000000000000000000000000400000016400000270000000000003700000000000000000000000000000003421000000000000000000000000005100000018970000000000000000000000000000000000000000000000000000000080000000820000320050000014070400830000000020300000000000000158000000000000000488258000000000000000000000000000000000023330000000000000000000000000000000000000000000000000000000000000000000000000000055000000000000100000000000000015650000000000000004561589000000
SP374Bacteria;Actinobacteria;Coriobacteriia;Coriobacteriales;Atopobiaceae;Lancefieldella;rimae901080237003031137014717781900600932294800709623000114361304051915202006000000099003280027051203004514905413528102234366088300167418001207001730811015018507003200410344600000010092109404400481490004016000092386024110742700620052624338601115261105370025325680452370020879000105832793882106436190560270024803512351190140012004941134364881007110681338039188000155032218028000000355610204134170041414340100000000060040000300000000201260000000000000000000000000002100000000000003000260202000001770349000009000150000080012260000000000000000290000730000152380000000000300000190000020000000000024806200110370000000007001040000060000000400000030000000000000000002105000000287013000000000610000000004003800000000050061390008100810000001810030000000597000010000000
SP377Bacteria;Absconditabacteria_(SR1);Absconditabacteria_(SR1)_[C-1];Absconditabacteria_(SR1)_[O-1];Absconditabacteria_(SR1)_[F-1];Absconditabacteria_(SR1)_[G-1];bacterium HMT345000000300000250355006000419120296000000003000000000000407000003836050000025080000000000022070027300023223020501450000000070000516039000371901770004542310052181016000000011000000000018000000000000531009000000611864958312000052000000000000000000000404000040002040000000000700100014808329110600900006050000000222800006600504060937000531010009027813250000070147007000010014000000000000401260580000000230000000055000009035000000177060000111312300030019000021000095000200149201809300088232700183008490000000800000141003400081564102840000000001500000006130006000000900001300000005033800000008002900000000000004500047000000000000002800000040000044000000310000605300006500007030000000220000092501762023901200720006700002700000000000090000000
SP378Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;aurantiaca00000000000000000000000279270000000000000000000000000000000000000000190004670000000000000006000000000000000000000000000000000000000021719040000000000000000000000000000081000000000000000000000000484376733000000000000000000000000000000000000006432000159000000000000000000000000000000000000000000000000000000004961000000000000000000000000000008700000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SP38Bacteria;Firmicutes;Clostridia;Eubacteriales;Lachnospiraceae;Lachnoanaerobaculum;umeaense510000010003220603012000003100100216182400000000530016004825000000700000000080009624554700000000000032000060180200011190042252052220000198000433160000028000000027214220098022000000000000170062191316213570220880000005800000010770000000041521293400082170000000100580000000000150000210900002218880000010000001250013032001800000140002600000000140000016270640906400700012008704800000000000000513082627572800340019426300311213001201709581019014585230316004308002372720100083591267018045189022810222024501101740045934440001881017959458600996853141801300120221870617042003486722933921907616508680066221527817022450301016260033224029018218050001370966292192674021493255850000122161561027314600001094940011927426180311861057017025400472031032843543734074673064332543300013046104020007318923203103501218101140533600003600640006220139377001334032490000013001908904512301023100212131162866900296770110699021210000177402400000118033253750415188594460338310631000001840128301190000273321001252651536054100
SP381Bacteria;Proteobacteria;Betaproteobacteria;Neisseriales;Neisseriaceae;Neisseria;oralis26674700023425264410860088063005407502960821793723014000310009000849010100842467731004684126196480003450520700019404013568008135700191628002411700491036723361149478488330044005312222614110026652431770082118133953101384636116900140013021326323001480211476045193002952812160052300320008001300010256220312112400050731300908000020103002100018205060024303120001511170870006371706070040107600130017601212221054515901600790003815660001265141982752900155230830151414310070003027050112022331790103103961002209803231030997720115002021755773030062147164757168110243732611217500007602415847009499297023678035746000883800096019379614600237001700001073304222561135003545897010023656100432880003910670271843700384702271700420041522480411300601478051922440136257561381871720183278551082800510053502059501240341035142860103972055002486704833100384200153340000018920165551066019426500013041661004100000028227003106100050400104001172010558000212241980189000993870084039903340000002903402730502056000059000333701190007136852112741792181000931006383915332124515041000020216000970021751069
SP39Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Porphyromonadaceae;Porphyromonas;endodontalis000060000000000140150000000000420000003000000000000008000000008325171000000002540004904000000000276100061240292000000000000060000000000000270343380097003500050335000000000000018000000000000061000000000008000000000015000000000000000000000500000500171175000000000000631700000000281400318001010000000000000190000040000000166045120012600110004276700000000000002700000000000000000000000000000000000000000000000000000000000000000000000000000000009900000000046000000000000000000000000000000000000006200000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003600000000000000000000000000000000000000000000000000000000000900000000000000000000000
SP390Bacteria;Saccharibacteria_(TM7);Saccharibacteria_(TM7)_[C-1];Saccharibacteria_(TM7)_[O-1];Saccharibacteria_(TM7)_[F-1];Saccharibacteria_(TM7)_[G-1];bacterium HMT34900000000000000086500000050000002000000000000520000000000000000000000000000000000700010080100095000000000000000000000000000006000000000000000000000012100007000010000000000000000000000063000180000000070000000000040000000000000000000000000000000000000000021000015000000000340000000000000000000200000000000000000000005916029000076000000000000000008505108000000600000000202000000000014500000000000000000000000080000000000590000244024023050016300000000110000000000000000000000000000000000000000008550330020459214003200000000000000000772100000000200000049000000000000000000000000000000130000000000000000530000002502716000000000000196000000000000000000000000000000000000000002067000670000900
SP4Bacteria;Proteobacteria;Gammaproteobacteria;Pasteurellales;Pasteurellaceae;Aggregatibacter;segnis11620010958110044400017423202234200416741305767844520800502645015026610100005013040057096037000037930008800035321816000409377700390060254622200000006120196063166929687500034404966818315400001606002310541523000000090404541543540001019470440000163304200009516007700018131121742005100028503280199007224650280222900052001050180410462800000516000400014130100013000019351900650011717515477400000082400110737863634913000256237180722000070000115011110000000090174321300870009287609120011013180956000393303007700001075930868105004290000553177013760001380017905651160000909209020088025000018258536002800001202600000701515300035004624618074500000064080025444198564690000133502525812211400002700690134083121000000529918612848120159600025017004000001020430000627860063100042154118823001000061780345211600010237029051000000801370300907623000000000000006496300000815662000027900314504491510000003630000035415137700000483078100000004100005300980000000003353164041910030450054200000550
SP40Bacteria;Firmicutes;Negativicutes;Veillonellales;Veillonellaceae;Veillonella;dispar161580754542365458832243149135649050521161381333482752313404022012846726060118126193545438249333684198651309237444090654980610593704323245750150208131933153421042109048711354591562455291372989164613939748135013690593794474734474304471923113202747331035452367258254215612271603390768862495136377444158512502782106997790482739482542663744103405096436422337218922205531302145764270454456161554108484348833419636675141366395654261386989188095832729128020817611110703737913422823524966314260531630227963926981157340539241440063710386063759133722218760970542632623508244305417084823782812213619924912874175841901044254336194162627312534566215793656254056011292974498112110388468175287283513103664060619154842165312722207816823808518468797382374960609371418274114277624695927232518257721104512549025870414820730547702871837247297012726738124313139212016396733351549426615598131539868418000505000017234194549123195100004044100000021000403169811710200000100132406230028300000277000028274121673956000029250339513114200106358001007067701032000007058241173000000032600023813764000000001260030500000000082360640000000222721100430000160004723290000903800000035300634522615700361000000041705935004518000001410002101033713281000605008141600560059580020017990785020000000861114400000003290600672551126000520020200230000000001460011000620001050
SP404Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;micans000000000000190050004000004331000050000000000000000026110019000080000000143000009000000046000040000180001900970000020000000000000001411143004000001700040000000374900000000600000000000000000000000000511951100000000000060000611000600000000300500030000000000000015300003800001000000000000006000000000000030120111450060003200000000900413300000000320000000000000013110522830302800005130019600007390000000000008000520000000029000000000130004217000004003520004170006125000000247137000011700000000000009017882820736900001410001600000000230198190000000160000000000000000046053000000144080000074000000094000001100040000000041006000070000046100000000000060160000000000000000000000000000000210002360142000006800042000000007800000000000
SP41Bacteria;Firmicutes;Negativicutes;Veillonellales;Veillonellaceae;Veillonella;parvula263177811233212374790129057061067311232520911835301347551295160810938178414156546829670234730685722962614966351434966145668795424072110573166687887042063229271561112203493661832103501124751959842293811601313096364351431279512183201221287722014389397601632149190988247359355263545341081703839170275749844119261457726647726325823545363199315538263432111004569131657375436214238196404546521036802703536381012171117922198861985657552471226592182413386488158674317100213345615119129982841326454424112676410437321896462102519038914117726964179879625698428480547713217694830168275204669157702453217925010933414441393258925425722784763925183451857260260236112955227630558464125426212127296927611430726243666712254888108229184435805931172315854972162944324940328110206608122161106306163109324144085825941431458603785106019865121821202693713811185401337162340195191930207512262139473408015334926151005811413181520492211101572577979696151219594270021604319778260016198980270246755383410421146529112436407341972073252583673712234426818292129783321805369851402301395861713962442061123530315600391223004658232476794561114409228550005102181605104738502524303813204710910934671012015055454738911220080189047286520555660366121341419916417262422102931018502330696107205428580138622610441241661381353761244520010653338134751000189106120611036889540039072203542112750486605430021072280342562102808710598410106117488047724518518214487650001991414002812083314555671435001171551170013515613716614134469535601339280100962380261339729312442609528338244014415277063534170156590006127
SP43Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Fusobacteriaceae;Fusobacterium;periodonticum9945817296511382197424351288145678220174935545772416198719815912896530186157619872470327028981153644132639317651350161319116653577207435616891938546533336772451560147020489364013221090358916472758117196419816812271198238215182140262828992635819433416430397725760108420178399712226152409435010011547146783219461020135740433382427134721440966382583310817771121710481186553532714748125901015621686366516521428518721794116326662764638930551788118928102613803103429844553489216817510671526271612343944418523958178061293167890634833401321274957105991271460150931293184321021452068267110121657561512231020169333027872109177444642616300188190265457054200425393580013701632218140165513839612295163019213518551354113462561242976144180216084650475224914451590802735032304142679475758612023337210822682710761352164064314692268807129011051121197433426232481191217971917127640510851623190294811321133821943777471288512543491716226812721723113937265814914993641935247019591175113411352349175023441881687248191311350254335443159190523508541126303156973383212918243235219562132126061925330747643415325760024606574164573802950947150650352323259502233423309188123946372503132703989201054753371101494762764831082817411638316562773158007354486482612912316940167163854824439360130099540000701002112370734116752648104827356238513118720337076353382028061054617910026810141001617111330182413232078018843072105077963727855524144812737348450119478543280136247100566203768071208213371284202931126016939190146998464070461421078467171700035464318251710390180003547718331187265242402016711824463120337561113167198569004552717396725382268000561157636023455433229668178017634800072194581548718092189456178340238610113184367395515981901600842170000416125018715360285418431263621122236467014506975168749604040636146429833018914453496930950482804174014042037038630840013
SP431Bacteria;Actinobacteria;Coriobacteriia;Coriobacteriales;Atopobiaceae;Olsenella;sp. HMT80700000000000760000700000000000000600040000000000000000000000230000008510618000000000000000002185501800000043500006000000000000000000000000000000000000000037430000060000000000000000090000001607000003000008000502200000000000000000000004000900000000000000000000230000000000000000600000004000000000000000000000000000000000365000012007000000000002404800002974270000001200000001077000700000000000000000000005000002240000000237000000000004689014248550005700009303353228000500000000000000000280000470190000000001516282900261800000000000000008281614000800000000000000000000000000000000000000000013002000600400004520000000000298000000000000030022000000000000000054640060000005000000000692950000710000480
SP44Bacteria;Firmicutes;Bacilli;Lactobacillales;Carnobacteriaceae;Granulicatella;adiacens512141992626404711066133916391515213492291296378412729255991059832129419229351307177810328837601032659111713018078943652984143916448232323933281358013972061730818870123116268721059797127568615984441783190641411448081960877145213151742707196121681842213243326574709001032995450326629146292134857591611472186158296192425591319864160115321472108912076127254781813137518969757772335107719275421150876756745674152862074015808641432114811562006791865126236017251094821103710531923865567118164811161758143117581137190455265560410571372189047498412551066903256814841567897517123815451490154514381379763210730802151611801249671686611735165166011639608335559431401099370100664278838221651453144339424411166195482275726497371496667863246910791033849942413138612251591117212081550151520427751491786800102216251902110736933618381126839820658193010586695551236102132112991029740194532112661105106298743816901387166412751411227397485810964093433119015576831289787822384227197812338961189799104579343610111096157333971301121963782114164617741472146891711185509256891148925132646110902228121422751295743671154088525271208241012749128651801914354341672223403568228441991994878152942901884053014901652679801431252554293926491729194583140212926828549492631247413231916617149450314016887531174885261581013081192436699787856246883229446763996837111541291192536561552567333483793641182472226116531331493711667598382199468227137338927743502311721532235813892442312031821282232530872435511412190663386721252392381001251273876526927510031607811116885969512401581402182301202411223310949124663181561813094362138973100927122232943696484383932666934545712050110291286783147413317974297184223465942726631256005273544779838038571628941193314819628313525351293224799323523873142111662417812324081675995110125287494205014631083985211818157520759419018129546651927243642989011694212484111312451816113946251433782201082916411553616887454130650636252164168677112167401227795847888353823162419110516239984125413559254742327020198285131010471744157
SP45Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;gordonii103507461114008201093210113400980685119800020843791027188312064303224362481132782155502441613890586291614055311986021760018312061680080162730498418120000550507901390024310213009513204777753980208202651702182615436432350809001370102002701414110000529432121125627190012136680891906376062121001004100148480026648409581460095000012342006912215801331102795211362541945161098092239210201262710764110018365510109000421503424022532170000700228202680440312745222104118701601651250490728125431067462102715170008903804026000043319571191013548163334415200091480655036615484430023201349960637732727912644338907244106092255024108713329322043118901964811235460096569368734161922100122120183423274081145456371115811841171651540115383300549001011513791169132116274102711000198026949002420031484109402211802223533294875331612543414703302975890434808247170020922988807304498924590001083811814662478679205414295590065347263353220501425156084061124839468220227653247239191626166315340600005820324756510631824074151877571086121291279910580659727922184456128240216534180446248120290416228374048200328518882088541504586065070066075526875029004012886500589012403313136832853036094602034252110161673121485161400400272251035015100012004100561604990211658716252211556181136028138173
SP46Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Leptotrichiaceae;Leptotrichia;buccalis39302314170027311831153204702024084000012003157000152603600954722208610852130037161813050140012148010393861816023102400223018000026053900012022338154005628327120774937101513133859043631400303988177345034251509100076363330000000000171283109461156181622400820789109040025001300297639210000250660757841900220022800013309510231215050009300001240456029210110001200002000000010821500016501501334001600210002221102509278016600043000390890181330220000005420152000000002749041310159107762650039082840013090186729804183951944369180657113317320752110049300181901577480253126643006378227501488240487292710118026703404486133651711764196666135176912542095249717048924459868841180560041420000282144978323013282272844151587540063915490755040681268002061167412351013271328628532592931210116342001573009958301011280249498111847333065171102337728229001202630000023452831063101312239988090029000128303307410950122976937675319526140151181107122316126107100185502436017414213000721151090522019515314522001115334691004739323100961010082010103750229612570255615816580005900516156721644000010072250197288400501637012810620930159170531700938602024531040249301547000671406673298115751362085723594550500740014806022252259001360000000210220048233241336253200133033
SP47Bacteria;Saccharibacteria_(TM7);Saccharibacteria_(TM7)_[C-1];Saccharibacteria_(TM7)_[O-1];Saccharibacteria_(TM7)_[F-1];Saccharibacteria_(TM7)_[G-3];bacterium HMT351257297897133462730275612017074475185447298201628946132286501041241439275501311811885258358314111361072217860951252071106682453225110199551133115378322211132011013801311412606724201186704046111066653113318710136312510129845016620787100383452618884644851432175121043910026324511711188166981701361231821611060461882114245541457627310040380203700130983012251699571113802444987571644022056242664880215512519297815516317229799056213682147427807716226771864637229501731592520886711236319907535471111751245461916548602378972113106911758629930212279561404311814539089930860611143346810254640286242724211371731201096816923117788817324231107107174388010042986161251121076972563737510121830752470108926038705390006134242740370704003901230900070271608301840483048600023191500527860057000002130002000005838801352006000002304310431160178950006132026406820270400175800600004500023000805400000000752200070800000144880034000200022080360005029050000760070120158203700019000190050000060002000110000400000004010000086131900150600110000010287183000000504513350200000000000418050000000130000230000000
SP48Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Fusobacteriaceae;Fusobacterium;nucleatum_subsp._animalis2333483410151041221107902007900264100002595657003007908017011935830023117000066962560044061108020000959641788451757067000048152700008614671672048002011900180552314848000802818331044750102000007508430000312088000000030005200830490200112000400000101608000041025700200025016000032045214027024502080880010812700220231510001829205027023106300001504614182624100160032305600115300000900326113634097313001201003856850452678010118315346000049900012498800022270042663500000685625594214000044361100035320001460000006604702500230064510100002664000000000000600000153000033000026901630000000113000290002693800101000002400438150817515140000004800234021518700670000000055000035000063000021000200230070120000006100001410000000000326603000000000750000132230002900000210450000013685400288000000017000000000014000570301300020000000000000000000004600204000360002600036580660200000900000264000000003583631540003124252000310
SP483Bacteria;Actinobacteria;Actinomycetia;Micrococcales;Micrococcaceae;Rothia;aeria8772580160112063147363652635174913854469762221224579232143173385766100950201091571673434020134180561351182527966454678391014422308256643482345754676759110093171054275708301511325590016351236431661204010480140521461076387922032177493544644214132129926523996184415122723603242251421841328186008844899811350436601656494658013077101472756703856647101065368162297050032104219349439012917412135112257569672898931736411882267117529938353497316761456622323032314743848128351241950017847213734740192230389861362394631629675183670571835141045421586698723401851753549328227433392261471331691572411511975162175028710637941424142013651140673440131947360894431223185591401024263116514926168640570989914881720141429813717149321185769112413843415670825781211384396741872665172702012110113947565181865132652393608295014907781577282461471201036925392632429518013664153397843030762498398618231548480554013045953079847217349251618985475285202940486823162634668212202324782197940796339301121949254132544761419688611806108749132872331971624332660562107714633151242109031045230231943918992043480378281116461103151192691302460113119144642672182761021165299046126521411498170877784929124146165129619811182292129283150807140667172101633104325240011967225929783912018009178010935927220255668981148374158163998267766120921824422241146042113551752661112124718453947143222934873294666418797174204291994306726229164262881826719282068123274013178794482934483214709530134420216159113111142441558819014171566764458994015540413126871712202957853027085682278150426118010441532811751715155204096363205605561666090412764177444456616491473146
SP49Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Actinomyces;sp. HMT17174700000021200150150000814300150000001070900100006000018370902040300091927640003318003036063111514000300009000002633600000923190564088602820012860210001600060000022004900513001326060106477017493218071812019362800002015000081161109035280350000007140141151360510000191165030252202000030210233058010240280110186122302401800090001200000490047042810059227294000130007200021001050913002714305000000404811067250418279125323140231410163561045074028692472810183260621022370613050740670000054834019729010131930660979851091740190124003517112876831956359111221874173924003028313279112123683702365202201471185432022137816900000546132994614871150199021595140014310000191070015776000134026336611280060216213884072764052802868612025683498033338820653410231090657040017297301051810462411233114492404439189431239000002314147014412700137089900003815176801065050296000033544168720502538132014749267330004140512655472209652267010822125323452504654224138558018623330116521571653754723581039221851334006431017056002299601268001114016023195145766283008582488467437326022136158023333272177120128283570723162612034
SP494Bacteria;Proteobacteria;Gammaproteobacteria;Pseudomonadales;Moraxellaceae;Moraxella;osloensis0000000000000000000000000000000000000000000000000000000000000000000000000039720000000000000000000000000000000000000000000000000000000000400000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000150000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SP5Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;maculosa5910000000470070005009345000068400400300262000000006004161900008600120040902000040300000001200190270530031203438031020030011088503000020000645009022030000010106000004304312900000007000134300024277007041451005001602391340000500803132210000130400040300013000000006005040001000001040003900611866090050507004103043300010513001200720032051135700001001015093306402000001801301856027219622530000250021358100065430330230000000026090800000250071000000000190000780006702011002918301230642631115640034110180210990057004000001430016027002690031178110023042302801100006741810018430017031584518500131403200954267013474450000018000530031710000673040000081380000000000011009800000000037000000048010600130744500051000000008290422902300000153202470013504570075780000293059039000709700072000004210
SP50Bacteria;Proteobacteria;Gammaproteobacteria;Pasteurellales;Pasteurellaceae;Aggregatibacter;aphrophilus18000442600009569511942667512060000486535367201232000021005314900756365302656377117000004008132760000000004101583011841309280182507561051206501300005802400000150077104500064095289022644202901082146769150034340200100293147961630000000487183214460161612920302002711835000000763271011001500210201099106196000010003019000320514028346054000000003021800000000000020074100212615100340102000001102400501211003213310017020301621662087325386516006131180071389700000003230814923161050100101000006802180236033733264216985007393602600003157312434642400000016002831272830012992891500136153181100000000039003050000012100059029010705513042103512455465179440117815130010300003380000060600236409900087063142115750130068878518288718610003370731300223112785104700000004871040830301648723020433200164068112706007061090021760000052000347218415350000210019501033004835195018033614400000000000420400000000032360000844720123532376810032800390000037042000200001431000001374460054513706383052823800645700004941980000000485000400001807014
SP501Bacteria;Proteobacteria;Gammaproteobacteria;Pseudomonadales;Pseudomonadaceae;Pseudomonas;helleri000000000000000000000000000000000000000000000000000000000000000000008000004634000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SP510Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Actinomyces;sp. HMT44800000000023000000000060000000000210000000000070000000252700000310000000000000000000000000000110451100000156100000006000000000000000000000400310000000000000000000120000000900000000000000500000018400000000000000000030028000000007500000140040000000000000006090005000200060000200700000090000000030000000000001000040000260000000000000300011000000000000000000000000014100000000001390000000061007200000007270900000700400000000000000000000000000000000000000001930073000000000000000000000040000140000000000000500000003070000000000000000000005980000000000149000000008480000000000164126700000000110000000000000000040000000000000001573520000006203050000000000000000000000700006010000000000000108100000002790
SP52Bacteria;Firmicutes;Negativicutes;Veillonellales;Veillonellaceae;Veillonella;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
SP53Bacteria;Actinobacteria;Actinomycetia;Corynebacteriales;Corynebacteriaceae;Corynebacterium;durum13611716813523508200541951226959242485332246022580220010412151565119765227119110290449271470763588601151880187425326512010541132261233191414683670409823727638118407720198407505370266079378745311771481520415354201394436282731863285332942177471994028094012622575424312633281142041011941035340591861915113773430125159114974839952902781245010173846159213020321013382510011226658710154229222154850516564992234112818522022202850573801371298920580413110301756057517029211176383526945680117106205358175628134732018139735602576641985179667001541634847401673402302715693185412133150441449725211316047029361161867559119459068173747119042470169358471751250319010160610154426378419984659201914693013319987397392054016156975111033156232107959751236243557131174327817721015702431033348652666398198610520464218041025241820156143465109313412581213557451439135433293106842121434298365583272791873449124814324211217841627881021548262653350532127183539194847776596334114991557453151342424384302913273927487872215784550526630275538185812280120211399427353633687298120773010642356165617251574245746941290136549421204791706391144035431933684295331307029923381067189163122403028111713032837110027254323107210387221445854542419774448601341552874523496136150045617141922461482465478678483344902353321357108325753253528208160534826161961219259925231831416356349188445185568022383112270642711251998600229365332301301475485168245474838220756767409147035701822833213101144981891541111286986521721801581932385161294444029386328216475242682320291065105982156042884424331481117467942496329324871109211428753682897117529032731911791188003642446590415133319842589223434
SP536Bacteria;Proteobacteria;Betaproteobacteria;Neisseriales;Neisseriaceae;Neisseria;sp. HMT01800086000002112430000000150010061800000110005280000000600000104101100000140110000064800000520100000010000002400000000182000000001300430230007000050000001040009200000000000000000001301200180000000000000000000003000000000000130000000000000811000142000000005000000161600007437000000800000080000000000000000213500100000012000502100000000003100500000000002300011010988300000037022015310015870000000700571901290000013000079100000006330480001263090000000180000061000006516800002576000000000149000013246000446001290099081000000950000002215250000000000000000000002202600800000000019004080000600000067700000000000000000000370300006760079000009000000000000398875680000029900409000006372880002000000210410022400380430000000007700179048000000000000000000000016021194145800
SP54Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;oris702540510211057199311423551403732267536114110241349768123103140157491248122600374812140792276279650001018391151890131875170173006505721335096693872140141244261171650502513124638153212312539122180837030260683767270192452060101510000103821411799516404009470232435196176101519480113340311017061615098000101579700343291516911135891354318592562662590162110321385208141401851401014651443918110075262728089820901330200162064940272371610616021361055075415320878312121100247652640222082275223550857841810742314532813630018016176033176771241900366104924151257303411918712099481580200140005302909206720914046200000288000000001200000000000000000000300700003230018220000000524000007002331900012000034000007105950449013400000105001004000180000000002828800000000013577000260051806700001260000026036300401900015700002000446150000300028000002000100000000030000000000800240000000000000237000057400001800000106201600000001800161550550250002000001527000001509011294000810716005300
SP55Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Bacteroidales_[F-2];Bacteroidales_[G-2];bacterium HMT274000000410000054000000300072417950000000011508000000300000001046000410200000041212430001700000000602086400031255501500654180000000000150000004000106108150009110080000000000020290200000019019000000150000025013000080004130311470080400014008870000225000001402000005204000150170000000000011418001067200424101900004412080000000021000000000090175830005673001200000000000049000030111165070000410000001124611196027290164000088412016840005812084001142500019000023300003000020000000004200023153000184020949006332342317026091000670120620000228601830450001220000220569557028897000000160298000000056919016300302004800002240000003620494828500000005060240000088180000213249000330160000001900000460001800000130008960000015441236003480830060760000000025000611015000000000003770692762204826000000702760000000080000750000600
SP56Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;mitis145910561401716422142161523084616012197510451211720948161831214283145391584125851062534016256544281437427367681802136111363378741717452217103201626498972812011790593226811655108530624412361575782622140324191949253201810897039481016291708581647217830662529143629085734513467833837064132757631079473571217150628584067735547522310321452095222996015653709982398544862958288240352536177743553000654431725912745178210534844231262051136502555878001601508293789066240102879375446795281072631431719313423542970432616914226964791268681247921832108443105134217434361061581463619224635081595636237712703521261756398242418594217992817582208210776886704799390320711380434124010586046306821757123430918561460200521549799991406394220338501447334854665601595717102544954964117572201685677170722649243010847847107366641788445493438510952844137981307487112379773190116416366661955499180418934861541926464417122216771665433376845119236419963939194321239916428552736952185673775036783499268248871172646327634047185435034767043264596129817831378689274175118333011770692143448644651114906116125215695161359126412480016121502254100053000576928788011013001137901147260270991502900202784021110533435740165097042702113600071038001400003322015286425634000692831016515107150339203012000073712590280011542803236061280085001528160034102322458416017064300241182528016486000630030200000029301029183180140210706720062109191011580171401476600501431203900083927965149068516370809082011116253460004480541070152119500019447104146918632223220112001681502351511780800121501830039039042232348170017131119800000814687125140167043000065841511612015114866183610656188615330905365181338100153500001280
SP58Bacteria;Firmicutes;Clostridia;Eubacteriales;Ruminococcaceae;Ruminococcaceae_[G-1];bacterium HMT075138340263511182470209123234624620879290168509664753924936041652342250133841130404941658819129901651658107393458361355942117356121114247763341190027825017496660011387917130014019529185412928782513920621150238242944940400446311100027655113450227414431229419213585012333829943000518437227160012017834178182339265650332309341000420413080026873202160120154002495792851087000722511229645149155388534100137017415022161805404160710183773181894558200600378622602261501863104940819272817112718721205051110194931323729703162324600064349242761971617938232015270312117373180012162883500002429299113033441012100242014271960036370059059183478418581528436104300340296345123170031382067071016201511371750934777158954219535551012945000005031128500960057941931000155452190250027417717344124510565288520012521126420334501172180000353836495022241128156699163111062462002568131010000007961144574939003070375460028213501700402520875230020062424801303003237409713026001420715705852300000603020430096361260000418223020048672054750002203221748016700003004525338003311027501460004704866427602078358435170014640030015905800000039003214211700005
SP59Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;sp. HMT3140068901809900010213606131269145181657500692141023112364554214010170000048013026146100635130200502411004270194014090181500502367683707926452610144614909120001800330017604001000090822201738712360861412142051602917501200001211360294040311503109173009214428067000013792666122916427005174000101104292084801929520163742901239430001616012203012409006004264601515592524044882013047108536131500133603417700220035280451279000016121621508172505917156130805323911752900001814172011250015117522510190700615000000050130012298169524173590000000000022479000246021511891109050003000000050000006500800063209000650000001700205113000000000000700000000000072400002322700111000275643374000003204000000172111001300007430400104003500001434595141080000000000033000034011276291086006000000230000063000000490001001190530000000000000370000000000000000000000000000928200900381901262740000044615000000058000000058000010
SP6Bacteria;Bacteroidetes;Flavobacteriia;Flavobacteriales;Weeksellaceae;Weeksellaceae_[G-1];sp. HMT90034420060004310070000005110006001190401300210005480000580101314570000013800060085600009408300040100000501300191882431904600043061853231846414604200022150220900001570040300000014201060010150120050331301000000070054260000367000100001202202100508000301489012050039000050000300738003000700000120060025500400704000000140109021721006087209202007703000000125000000000061088003220253600150529427301233604262396018111314586202060100181476416170036018923130292806673234814706492551128521311110120803884800724611212005300193067204504095016885100321750152954353931007448124660222101517832881821425347023414095898451880272431223422015202410123779502071123300000365979126014012482600043131881963628030110803614036901322335923230000423427401285109030245020200133041209893459319906027007000501664020401229120016001123104006000181871870280791518922802760110023202165590104145302720165012082511722083301177212487530791000271454900022819000002006003522417793001305
SP60Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Fusobacteriaceae;Fusobacterium;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
SP61Bacteria;Proteobacteria;Betaproteobacteria;Neisseriales;Neisseriaceae;Kingella;sp. HMT0120041501000801100000000332000000051000000000000000000000020000000012000100000000000011000000011000010000000000000000000320000045001000009001070001400000000000000000120142500000000060000400000000000000000000200000000000000000000000000000000000000000000000000000800000800000000000001400180022000000000000000000000000000002000000000007004200000000000035896390100001100016000024252065000018000000000024001000125020790003400000000032000059205320000600000000048900000000000006004930000030002580007400012000000000004680000000067001133300000000000390130000000000000000000000000000000000000000000000010000046000000000000402690000000260000092036000000000003500330075000000002600400000000000000042350000000000012614000000
SP62Bacteria;Proteobacteria;Gammaproteobacteria;Cardiobacteriales;Cardiobacteriaceae;Cardiobacterium;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
SP63Bacteria;Proteobacteria;Gammaproteobacteria;Pasteurellales;Pasteurellaceae;Haemophilus;sp. HMT0364978125880520107332702110038353642291291121602703908320200141588141017143410520473818029523125141232449176011400630010860102225120589812138148023131629011757559712041113186606976278383826791701956010382014540004614228721869149101124840444602300429140173333110381041117543030710007604124471246044320202013060300025740412651871119130271123306101840928180004400212055194444411619591204402060374327134110877850618032364381145911347729349781030581839754731171701571780392624032110142701304287117028233295414046009331003258750426391430132135035528352500134630410767341264950422021000440188018000016110000000000040000000000500000012900000100060180030501960027000000000000000040000009000200000200000200080000120007000000000070008060000007000000000000000000002701400410000000000003240400500000000000010000800000000000140000110401600000000000940080300000184000001600002000000003000000010000300000000000730020000000000000000000000
SP64Bacteria;Firmicutes;Tissierellia;Tissierellales;Peptoniphilaceae;Parvimonas;micra26000155526000000100000001729000002501500030004000000926575005170181360010129000700304802340500050100810049413053018360232090235034686217002012585702500033000378052012555001800380019412000260000062000011134110000300006152700500011000000163200000260231000280003000000478169305919038240613314550640018000060050007705600723005831248081655037971447118191114192212014003530004915018701940018000138002733100020000002000050815070410730000000000002800600000000000000000000000000000600000000004000000000444000000000004700002000168000024000018608000400167011201660000000050200000000000020000000000000000000000000000000000000460000000000000210000020002000000006000900000000000000000000000000000000130002000000000003300000701800000000000000042000000000420000000000000000110003900
SP65Bacteria;Proteobacteria;Betaproteobacteria;Neisseriales;Neisseriaceae;Kingella;denitrificans070180000021728122611206517001522552512120257233230724220133111091115132715406101162883339132240010900045081320160446125280653003706136250038588116000422100016005650160007575100750754421411832025611808491720002101673080306601310181800102905401134579165303212858396229025400000000000051201670593600100000110014361104232014269012610407154450001320270001214801102410029182651932621505712118000001591855120556002500507321490004648039002382150002800332014671087615430102200014001934006023039270104734150301286012232293516100660329251181350378124714208660910921161712804109352001437271163555227306071946311570638318139004710592184743495475283144622893880000718170291742456354742948002143991118229300231105991281710012210513018113500795514500027660328042133540683144932159195031618505092617280505132312311129297943803503312401091239333401932188377292934914816499115112109518979056000295701251300017504125272904400015000766419173479297137570368677491654315105111096497453140121018007317357904739217500239591787241669155041873802163901210425200531731400027115141771210700152455904920719590095002382224640182011000583132984188248586058186174004770048274308104122362822901815598118501321211583075704533629
SP66Bacteria;Proteobacteria;Gammaproteobacteria;Cardiobacteriales;Cardiobacteriaceae;Cardiobacterium;hominis1886102280306676232535723045291790361758151091411070110660045166026653293241208513466906279666464134702207665012201511001713121205930053009249110623302934052134332332553326637101340213213011613315300091020212034913541458400046711177603382011155041106190002804900024532080040549751765131176103008380335660046591072001001511180151302838427101807137208010519141540301028002200540006001637947103935381318061743344962220236790006115647221047541418230612004510414380420154012596305157364546163364246142132264796011120208131129483766440682683614195298062515325876293571306714181330716225681406578711983761798942452317333022614738139111567761522920443054362102734400333048571527619814311817603980910072451841576557145147160249428047278103194654831331381347125046053714768143742120386649320590257322606622754354954243259416226125126421141117500354148794109317156201467166926513061122072131883412141232253889831879119513118263108218414088693129484226128162017112925611698771224665219602062904220315170760050071719726118869038843533746154427094432651228317734480637571054210547494132782181801060786995901610302317779820758529610432251432785751575773210284152251273632858038165103826856302176215011614578411153436138491221720443553895181545017138510831431022653024970149451378147233640590285159212167701322960628
SP67Bacteria;Spirochaetes;Spirochaetia;Spirochaetales;Treponemataceae;Treponema;sp. HMT231002109000000019030116000100130021000000000390164039000050000900691804030812000000490700000000009380260001800230626002413045817003001400000000400011000290330000500000000000402214360500000000150030000000099040060002680015000803000330637270000000000001397050060040000000000023000714502000025801421024170220024180016000000000000001204401206390005200000023000420053300005700100700000000000230900560120000560000000300200000000000000000004618000000000000600001100000051200001800008000051003007100000000000000700000002800000000040000000623170200000000400000000000052002100000003300000002000000027000000000300000000000000000000008000000063217000011000065000000000000000000000000000000000300000000000000000014100000000200
SP7Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;sp. HMT06646187020118921442661214188331222998199962345322425499036916454734211102116204134619707276304902274313932151281421411744286061561699633965357010932643515033927380924207609615190315123026684022050346306121412294776223321418328992268159113796819719649461832975110619825152110503989712761353253697158712503267693568355871368182155312820710323552094090801562761493692013549533220335953404551315491317184159162215657571295071127135711101101011015952715531528071282916285185678701029614758141608495107441827336217451435922466175145632512943200637502049857430068184188317141140128695202582244248854534121361404025312307016115472663602161587326352471453854655922854834317833125221320683222068221217132016214210515596128910117110325258008478331048634351860014026039210001862611557100886902926439366118428162474619722107158126648839147647111013121429069132793725706923538326478113820415436791799128827820312467645775740111842601743600230005751551802304003005606025060702070000001000001200060001960540060000001004000200000914000000000600090000000001854015441100650126300001840500000900030011175000110000080010319001102288439065254110070000070397700000000052301300100002147890194680810240005000000135201404002000071200070000100510111203177118140505001390100313236024001002200048149540500000673000611252160000001500310
SP70Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Schaalia;sp. HMT877000000500000000000256000000000000000000000100000000000000000000000401171500000000000000000000000000000000000000000000000000000000002000000000000000000000000000000000000000000000003746000000000000000000000610000000000000000000000000300240000000000000000000000000000000000000010000000000000000000000000000000000000000000000000000000060000000000032281770000000000000000000007011230000000000000000000000610015571420000000000000015000000012000000000000000100000000000000000001555500000060000000000000000000000000000000000000003225485000000000000000000000166727000000000000000000000008405107000000000000000000000000100000000000000002110000000000000000001800000000000000000000000000000
SP71Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;sp. HMT05701321616001013427288109362116215051323141083600265147115321216440554551005909069557165003743056177721452916012856404696739103017801018509501435247109465164360251819596418601272111013971363417212835234681080310561801024421202786140205254087310508671421250104249098310520381142086011100000141104094312016542306921429635834260052917023915028209732145303557141401251522942497340013811167252011470411571256002814198013354071058558361375422634517623841593446122017396406031035364004317612412584841100541220145333313619473021308845619105663108032126280001140912471890021203332135928501869919326654000015035513777576000229587212218973999141331671489108306258149000000000000000000000000000000000000000000000000000000200000000000150000000000000000000000000000000000000000000000000010000000000000000000000000000000000000000000000000000000000000000000000000000000000000070000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SP72Bacteria;Firmicutes;Clostridia;Eubacteriales;Lachnospiraceae;Stomatobaculum;sp. HMT09720000531808741361700142494316528805908500931183110373640110385211348016496392421617621136100104458671886425927302752362928287183312538621131125042010721492885568043214324100018903933345487920835113124687302611798095730000506231255022256098228792736734019927262177112049451041894647908290733799425542191280000000779301891855700107526638268191601579741109310560387800014212276933701221242094570254171388916160690130030539761059606952261507198210024464841413957046845242137978554711421216714020920942141311266321922117153831190191213604200000001544932040194615246643135231521715319384619529625581597623234032119622973170516934512043000005610126030400000030006360500200000000040000013000014000013500000302100003100000000000000000001301300000000009130000015009900012000000001200001500150000007000300000307000000004900000009000000000000007613000000011150001615160004350000000005000290060000017000000500000000500000400000006000000200000012500010000020000090000700000000070000007000070000014000000
SP73Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;melaninogenica4444614131813685791801325414232884610138846433115385535873206716511651205403381710256969102814564852389618024592178990786435939151164322790615261100356157720721774361414435190553453542407456433745709105039542052307615073598226818617501105359881672838631192610528416618215048376729183381552304314342045224427333645526386945291364712661657508931261862281247811631823923940206531265222206586692209216573901786573957216409608721932191415607559121347271771319540553485162101209332212107354271624364672586257932719529886312687791141617982173263213142582107142119126621742350140231302198606333737106211759703682538884650660833035362671184502012322089327111789011715134317192011920646228612621936114979381110444052123127326804241260314772903705543221030662052737304140329113045332365541173114065553912204263271384290838263124531521312954800248111391803115031231674501213741051372821462196172913834487402262272525263360702792269413961864274939585862416112019586163795604027542130121470071587212160344219445724731215720251494539177013112175686438931401532426852979356912557662253729189215252833183135979165257248371907661758701296124878884556482421365948178895382246839651652231113172383690842671881206569088564437047430673948009992735269710306668121008930245140331104901478115210482033181562862351901101219804624171441142729352151763623031302800144130014301234307352243699083174645612354985012040028516583014020017933329936414015006441201358231691203409410125454100060356022038095705292247160913318493185142755162919692833222600118712878650615603820250260014511171150948482778680562737104107108701510551086023306481601200468704030003420000104621500050236201640600358507971630168024882003724215327186320000415254691871143717514100014602850015504082036590270111874330916591100290960
SP74Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;salivae105617983952531242362802975332331727617088454161157187359310712101311724491280289843032028905523522511514227371344083414231124124146355871961811602614251149658485588108089373577163324628735191330134349653926812832215686711677470551101705303530941422644221310473601296018612312621229321430266326393155001299516529501082408611885158103327301112144473061038536311371836746040212360270104736642044141381428481751113551053031073416616123541722501212181031462035276688008139457952129533514055756213264157647233620131311072213438331822381414371587925942114661439601891269326232151951827845109405831242861663142401348895711513050361338451192402492633819522770972711473903867841682156180454399873334278263729529963550610791212444029582532371054982257343148186881562501121589601046399151268599422612839465127278660196000000014121405001718000403014000002440007300139011200091000170000000000172070095460002420007000000000000000022011060004435500000002805700000000000003001500002800007700000042000021000452200800000157000000002040000153435021011800000250006904020001105000090006000000000000000460660330000000000000000018900000000000080830130000000100001659000000000000043300507000004850400700003180
SP75Bacteria;Proteobacteria;Betaproteobacteria;Neisseriales;Neisseriaceae;Neisseria;perflava294021120479551794597111425313219595900132082013900146033400027898385232122826188413861390704604475400480983014215319813167346271209123263801535104016100924330699206813357229112617693765051105520107700001549622449400990223125174755335054802757784269202511197822250177040026419780180191425164493304321565215104025500397339027203703017811907005033226552001140521261477900003180049162889100670621829134672939941800015370192201036701010138240918913522641174025901630071808001330024663000181613716743811757715469203482449180055352621945142886813269335650321491103418217119200495909720264377918761964082983801917345700003915432121004941505510268224452001259824067748717780169115562307922999490559141400067019594038343022355032910216380070891901530243202082356013810363531243261149378312480000441304205205636712433835342520900035720018960001600000000000000000150000180000000001400000000024000022000000062400000000609000000000000000000000000005000000000000000000000000000000000460000190900000000000090000000000050000000000000000020000000000110000000000296000022000000000000000000000001100000014310000000071000000000000043054000000210003000013000010100000170700000000000000015
SP76Bacteria;Proteobacteria;Betaproteobacteria;Neisseriales;Neisseriaceae;Neisseria;elongata89295014183450119309613938196090012459691181333101351631020384451827411243691800043210424736161734220867292751926501162933913101752481271304802082240582557582601397707755123000221282226109456176416015689002468337159327711649349591954623910790497301391999602211033760006124197002801371704018615533311611519584610978170273417134289256603235707525910139648838164421951001062104153736343000421827035151043001115965105849231486657779914701761240568927111128557950379815631059000611714146025481515018110211191297331013441888226200171126317819574447169023063250037261719144411209698152350260576580253310314399843141430398724602581211232743763901397558117750187699124221080371581875911924348132895011124979149835910939323912033585182359322191740043145043736637920124311060141972377215419560163163470130010581518751914446193831152341982224114351802907380589639878202253181332717651987863182104624287910281740511619397219329503292419722122662610647436975430140815810960016832322701322178522902245181073122354419392271752817466262923017120640476510924048280031304881969604161010304158192015063680108122225290472142991155577013572594220499113141173522300376102303258917104424760192618823845940163827321338201930143637244412151305223670530782198774718596715726015811496178922591782171677487900901494919401072864786411431237724763455977292404233265414371191276197855673745310342422630458120705336612280050702721298240263901073133137606505016146163492201514471361307
SP77Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;cristatus_clade_5781332241066946251032352700766143618543807191356942094206156066255538472878372530131013565512515284226013028240161701193980143944659149112153282430004330106917163319941438727046221834313572898176146162538502443123712283506507925645693214730313710249533425034487380737421372642531175316171916261110779813110124125912830293462868456888063469660336989510863045252711334642684531636332002257533692412408946476631228013016528524862366404513003801612702909117423773807501153358934785641903292403414252744507128032381233430827011232043376173024821224641525828910418184321572572091608560594511283396691657527521351122592222467115498394358132137318300764133961130236952474021820827230239565911413403311294042295503615499235541030620851221770643928279141027359550268221520861051901787235164192105490016140031716481729443267140380191176541983644870572134742398299226240192825917684550587351724919089543996221138000224750359703143528243903574431374610006518623939518632417145402541141320369223333534777319017618931633014941118348679978916025817191118485640522023911929014925073191258045308910180429111685940493577053521190863325412063542452470504121640341264500514020091641224616029320756311536467602508218045951507816360232572211070150730010193919325442091480422445195760230476394001547135202220036339113246610002070009947366658062114683014041445528688103880291010317410326301641231070604600036012722513181134102731152151280380510067576221346293810876713051388300680120141040679658761000124210
SP78Bacteria;Absconditabacteria_(SR1);Absconditabacteria_(SR1)_[C-1];Absconditabacteria_(SR1)_[O-1];Absconditabacteria_(SR1)_[F-1];Absconditabacteria_(SR1)_[G-1];bacterium HMT8745500414500354221289300310202000141114823281120024011000471338633002001621272248423224041627018041004059232300794501035001123301423452250552822250194235001361350560285916786060520517050517244470130360151205711000766503900007922672272810643302103165000611001830084306525500058513310793140211417190030081084004111301322160242230122109000413241920070062121820528030152527112589619400437280091507701916082509716133000205120501052188141947209619197001225243200012010767180507143311301980101800033052044133392651035760206064003303163851760019012100970165357491001403324104282221518024208009166046130160061001187310175000542601151252017236696036309930283818500213507403023028221022834083014312230301251334545971934901664848001071561522000021342542114283041024114110065049910015517110900728221342020591210000017104108513100219338000073511019043461320016210269131607905660011281106063001366410511050059160523311974853861593222446409400004101432326027219018431820003853243341004976579119121571902026333001742157169000401809500297294116065066
SP79Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Porphyromonadaceae;Porphyromonas;sp. HMT28400000000000000001800007000007018060000000000000700017000000000000000000000000170000000000000000340231300000009120000000000100000000000030600000001000000000000000000000000000000000125220003500500000511102200000000000000000000000000005100400000000030000000000000080001530210000500000000000000000000150171700600000022002000000000000000000000000014014000036911008499500201000019774000000000000000000015000000110000000350000098000113800040000000000000200000000921116042000000060000101200350007000000000000000000000000000000000760000005629731019306900003000304430157100120000000000000450000000000630000010000006510000000000000226110003983900000291540001000000000000000700000010000022000000000000000000000000
SP80Bacteria;Firmicutes;Bacilli;Bacillales;Gemellaceae;Gemella;morbillorum55073082025170102351452311604313524571453075021137102894843667536220516421941064652351421251432132534215413414913116640151433261430911870620379577030360201280841196361167129744334041652283949263151210359033067321666736815252123120518480204525001149183100072629675136342323831351715451980296335450045074913642045716684551360018310986489230107153848505157041128867082800012711422112713130755152388932982197422257615073512632724445176278106094750922905424531918401718213946546772330394361420167689794413945137273828361144663113143616482552721316650232681828601069206628231765714927437794067829144741642244161146748711510675163480901191169171741040267201161486002415496012651186163761117129456120537725632315003501160977068439489014237686465761494428943692113047068756321372953657917128362124161122862531733364723404837150383181714130078325884576467692063655528498517412210881255472468321350170590261422221367176396344200104224486067158731043251152527556109162199511708919313135211510652605111269014871085011138648120846275280173409160044433620927777660397259127090320182529878285767481815731841800180242482487133382343047146211704105821503239342771112329227366810322540427433002734974197403783430752493937481732167636402032471001220111890135716213124792015339166343392149323124579614311321652191273443368857437619600061158167419339868623810934630198249210185811601048111485114121382872161422213151543102002045936189920211830
SP81Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;chosunense2866790045610841146101871508097464641909102301366592694751073349317107440364324697376491634671772326382456622232317401418121282258949944177402044138305165096027496785269286430153208201228111417701041973130645011891023311485374391112161197232399293712290542441920721118132645639313363930161521339352946552496485390268312812252325242853619252607363470424224672348720598345295309701196019137933533318998342041722798178314942585111773407295344321560562109332514832121650006373107211861517513993105812504432103795097381815448218562171375349100860120925019065564635793451091176571304010438291145561190634455685181875036796148013731677118049211019926126761224128685351252314477128110811042463812827522544254043720915113196119914151018220298341036310560793275261113439288521957976220160823113003331411630746824076152535433367322822541753717766811862179280969581103647828527537270113126147721171979692535815188673183659262611000180358170074000000077000001402043000462403203243317000240014243449000402400424902712000590000005806037079000480231970176702900000001101800000004740009636000001730011170015000090213193110000053613015301810025122184287153370001700156014712952039026257159900001500000060000025802702570164700380028800000261100005892016300020000144400154309039130022424507370000025327385001043729400000000000000004389000530799000001008749305690000390110192553041029920025036011201213012142421329636570000000070588
SP82Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Leptotrichiaceae;Leptotrichia;sp. HMT392937203120781921411483815310512838195814403701330142475500756502537763334380516000012331832514011672815003628444054729334005740138070018321216012661020078219810521027061255135813191169146551685522512185044901001964828824335001111555527065641000041821631367111100190441092301620110500005818169113102201558275221611556430896160142733423093138100007590222409056085221005287472427082111000033045460837675010481013362896726701207849081148273023130821030417612122500616812519007170000142033155111015590402316966102546409213540616628818160728122931002193969241555104464201150927113870109832911415744477619574103365774717131010171239018017512401555745110943865129304029014502602111301297910141101898126004386374015777351134465941081344442046515265109895698036832768033271049929731631040664573689466704551075501334951405121001182821553762282135941208977905660901285530220000032031717617360616846682244905668837545936890190145554071561348215369288815278588165036160160242356139717113904351065317142437343036504591012561564375576565296757001173720176453096611301482322101142194478851545014101095335101901330510881533314281071062041037251871307914016720382014992245127836770217371500118120939129169486508178054605710216726852376015247206116601221110414000020431670224254870102856034424624733
SP83Bacteria;Bacteroidetes;Flavobacteriia;Flavobacteriales;Flavobacteriaceae;Capnocytophaga;sp. HMT9010000000000004500100000000000600000000000000000000000000000000000000000000004000000000000000050000000000000000000000000001029600007400000000000730290000000000021000003004500000000000000000000000019465000040900000000000000000000000000000000000000010000000250000090000000000000000000000000000001053000030000000000011090000000000060570050414200000000000000143001100320000002600000000400000000000000000000000000000000000000017000000210000000000000000000000000000000000001316100002240000000000228057800000000000246000210120035000000000000000180000000080270000401000000000000000000000000000000000000000011700000000000000040000000000000000000000000001231800000000000000017109600000000000141730018011500
SP84Bacteria;Firmicutes;Negativicutes;Veillonellales;Veillonellaceae;Veillonella;atypica103180237811741670153913868572241396267911331359764311841379183018085851242540226901200011011857141236796171386432982286140376226306330412151433170924161156398962156845733231710611166118538770158825710908846150294412394265223064057410077566480898141829013731901157169313432691291242948211680010821790210153498271806550993020925125906412277121265892170206376468541085466153270689720622282383001123310251996124255796825854342000090810324143491414216023390720677840117142413551014899631987660322428666110451083801120127730111938331419101888891422891572199187868178109300231675377252264184625025152499159729502244825203947110715082911628323451015105530098945814521282113520088614963621116143314991454377812251915501319178528131149622573080252824689220286318781459149760538210413101931092235009961165076990364033235767881357197873832814131734705882609503615179123641582453505259816470039941052812521174298122506418788790000938286502752443124256012857328891295472853444163861633273326700380210000070627006400043005510150000000000000044000000000000000000250000150000750000000800000000000000111100006000001100417900000000000110000000003700000000000000000000000000000000260000000000001400180330000000060000513000000000000066000170000000000580000000000000000020000000000010000000054440000000000001400000000001000046000000000000000014000000
SP85Bacteria;Firmicutes;Bacilli;Lactobacillales;Carnobacteriaceae;Granulicatella;elegans15979011101521011334112332860733056351076123768014522862689581084291464371321409462074119145302145025101543571085575947286437112329510333190491818474134393090088061801140340291116903714018511383658824619931189441599662371231101598524126225102583232310159149530306048011822102031418519465201864155524161495139231765411579200609115163811855600100461573744552775417838157270392513731936193350011058220000193713466311102235702166023524831860155364011259401652470414926072042252662704856727001323064340271000419448119454096800256333175890115600351052191013010297473441010632889047133703485293342232352041152283510000380662351956981201246111854810123514149658628200146273285600870146752282446067718610782010202371400000210000171500024051000014028130110072803606001704150028451000924008280560301900000000033020889000318002805410001390000000558120009700007100010100010526130519032000592013310008022800800001225403500040000000000361102900030001200001439300600000190000000000000029009000000000000510140000011022107000300007000000257300001220000010039512460000007000110000018176000000070000130000160
SP86Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Actinomyces;sp. HMT8960000040000000007001100000000000000006000000000000000700000002200000000000000000000000000000130000001600000000000000000000051000000014570000000000000000000000000000000000000000000008990000020200001700805000000000000000000000001000000000000000000000000000000000000000000000000000000000008000000003000000000000000000000000000000000081720000000715426112671129800000801000000110506366114704711800000000000021200000000000000500000090000005080036518423164190028556000003740000000900005700000000231000014007318411760000020000000000000000000000000000124000000015004555839708000350171000000011207960120421590000000000000000550002420000002400000030000006020048209221900585000000000000000000000000000127700000001061151000000750700000000000000000000
SP87Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Alloprevotella;sp. HMT4731702120023651930230086538610201940143913431830129470644927100336471027848435114419609136101867336319046394097757488296256168122916116112115200711358002680661223018004604132200165422027151711756791921231762211889662300122127300232263816702105521881141167786640414220116440071128236107641982712617710430710491078101232780419239204274676230135175713199621731300221825899150521082334832455525615616323072519243734001651110000061115154632015644525382646436450911137501730172103511880024196514533215708007840003972130110861315610100510101025151604867049700676278236632342370101758404695915234937874941002536231148020186038128159128900618950923117018038315751044439463831254417014158803025301091121974190602851448731207510012010417045218702058771397407808044111500241800000761601180196010118100000117186117970706701628002190545206100429049132014980323070802450000150000002763000852408313233382621830700013821700019039959018001818113304821515066900010427135302717320749600195004100001611116480182400000315104695001100000072984011601382200002015539257262000001027600000195952063080000016000000520000190000660000721681600000171314633801653712000000007043301900250223200000071024112240008915041002612250420200457150000626959002670240122250
SP89Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;saccharolytica439030036000539075000630300004314000500018030090000040514713004005800120000730120016700000050110008900001570011003460000000009808252900210401211913217000732037748003000018303300004000701670000050000067840000000005004958050100110040060000000070140004100300000407070000000000120640001611000973000070000000019030009003506036790004001055420060400990071004508432107209166002056007037120728564369102001440030604866012972202093110148530418780184052601313101066340304613900183510266301800201004193981115700985556196715005120614880184122270047440348148010442000017809003133990263034073101322142221141333021160145852715364900021819820780029253205110034213872785001303400502258011210421980000017513184036113500092972306050707817090143250001600606059046002623440051041003897222700004220781140012402988020041010000286040005239001340000015497438651401640511731801658002425135731320154020300008071009275448101172980
SP9Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;nigrescens1241670088000072379264191835942023971925541110218180624604296267233131094618589001577232008702204362581855249320217232415020208134461226202050619011173619373292717938079220010763984362921529443715611415326396438085264243206958886682599056333115191365344646117446514010695511024142042158410115161411222506511860251900620000015771821848018485534100369721113171014430495439201274852214233524628710400750678701016785585012144295536940102624146851006822212510311270115393780953355286101352413111407821703049134281262977840139011651373435474440235452729325176351048732016815790311545931337301480461221111652851161729409519821208834055205194851000000000583761314510431147179207001450173001071003007073010804033000089320000204091400138010060079400834900203968190296035302422814050932749130451670052509030936015240533037400090121600240022509309001141510024816814000030080000105140000700111866131340097000003631104397912225000003310000442700029200007018677800005700022005000001200477000000000649256270000049931060007520800170452400000000000298311861900000242840022142718120337001520620032814031000010003301400288000771700218710
SP90Bacteria;Bacteroidetes;Flavobacteriia;Flavobacteriales;Flavobacteriaceae;Capnocytophaga;sputigena801293010235152302201685013023221882022620115184144721014289371571992611242291088204120312412113137771721292786550321113011312332755498135071801129592453172719049045426803413237238212690425010378774838572413641521182451265424260158256938205012124691238120918120178192131601436205284021445546771452216318305345110813231261438723315113519614746206353082849242273251783964139260839199916340665158472343399860329224218344364156102143501292335241720262584589301799702032162981045265205666901112214239076393281143578590424746050493081623981121812259698324971524008410748903433431012188125851071780792898101223928133853665792893033302187416677445127109112550181289345553925917327185321473218389108015652961992067122531649438508119205488614317545873627455901981492467431815418021944248556703697225491040587238393155341270152459244708287224513011033101716338282712944112016871681874115277433866465272965571825649329823312311646134302471689695157320278017901394271157313641032614339432252316448323385148251372218780930701142359749120928367171201622130649216565837742842281838278418953176381252553285827482822094355013433923886964137663251154125114731321118119964711138210782494941556318074939616101228290595253504816793474639847816788110429015402084267707888209073825959076647115721025118989622350940015122064425354018611371878052431159111477803985711045013779762712100924169826194313623406109526726754895954209505068963136238011768701481494820267724221132382154868621172823692700190117922815106915878712391514143887301408077514473501461463369422572691219199373106343211726321799937021940556458113962925139314184348737712808598239757494812473419815097518212019155247
SP91Bacteria;Proteobacteria;Betaproteobacteria;Neisseriales;Neisseriaceae;Neisseria;sp. HMT4990000000012320000000000900000000000003900005000000000000000000000800000000000000010000000000000000000800000200000000220000000000000120000000000000000000000001400000000000000000000000000040000000005900000000000000300000000000150001100000000000000080000000000000000000000000000000000000000000000010000000000060000000000004531090090000000000277600000024800140000400002302404800000000025900000000000150180006400000000000035004000000000000000000027000005700000000170000000007000120200000000000000000000000000000000000000000000000000000000000062200078000012000001210000000000038000000000000000000002290000000000000000000040000036000000000000000020000000000000000532800000000000130000000
SP92Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;nanceiensis1181082131633736071429451127227293473074225958941830811736501583315621324775848951492761122329724183253492126716151197183526666356434216366394411244134840263210862562630406246304182873064330160527532097078698622325150844516447522212116529718193602816187330767145386017426481016222617612331766415204675019619792432045347219612467133166217573671917472613783302132891042164181350299725435199262360463412016513567163611331200767574612851057902310020692382649111417607220192663784124216824226415531821421059142051828411330454145132015826946867137754289636868203111351624283129430145041014511608669469335831551629219015559631181360131977457623585602681946954079415010126229542434019113313124577096412499724742213445414906453902171723756498161773944645022444757891961923701441968173713761390752449321162627619655648282620900041515754839268802030000000041903431400000351412640002000505500800040020011010943218450118040000030503505006000882514001800016000020600000000000000033080054130000007801203626000627050611020000009153100840000000070023650100004002159950011000000001109000062301530501100008030600029701504860000000098120110340300007202046000000001501000007850831000000019005001303005629115006057000000000200
SP93Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;koreensis17100018070000000000000000000000000000000000000000130900000031574140000000000000130000001000000001000000015500000000000000460000000002000000000000100001000040400000000000000124181950000000000001700000000000001500000000000000000045010800100194529521000000000000970002000000000140000080736600000000000001518002640000000000024600000010000000002690000000000200000410000000000000000000002000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000100000000000000000000000000000000000000000000000000000000000000000000000000000009000000200000000000000000000001000070020000000011000010000000002000000000001002170000000000000000000000000000000
SP94Bacteria;Proteobacteria;Gammaproteobacteria;Pasteurellales;Pasteurellaceae;Haemophilus;haemolyticus48631161142661886310421256752797437131607363352941612247312172198928379243062019915524414059778111633336863597530117244190558128146283638455241561190529561010004419034440231013415711672159112926713720123949050303711323685210609245163492212662412112182015277114798877063335587168161275426281507559191373813331014455130283291123313330403140957552160919203311261417433851971493149942574679615405727614840911411729303626269015451152539295321223813403287701321511023071161642232711363152867711715280334652910288598156802733518511022078151796611910343084289020960946485527756531137183990832042396307863535810097303152723539800400170474784235017402841393532541212462731126202828570142172285103430218161388793146268116136105326777145012510690000912001601100001200000001192801800002908000000000134720002270021609000900000000050000000000001126069700140700000000000000000001700080000000001100000011000000011000100000000026000030100000000000100040000210000600014000003900900000500700013000000000000000007000000000000000000000000000180000000330003001600200080000060026001300226000405000007000000
SP95Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;sp. HMT3060000680000005855502792910001001813003400000177350000030544000026029718000084940308170000252112700349001281819000000588033321002922700014817961160010743600300001630000380000000000011401641740280100000016416077110000000300590000032200000040000009730300000793132013077000100260000000010818000002425350400278818400018290058000001965851002790015410130000001593098148600195100074150065000494042202900005200000141000003750255016801392840022034540402110000000000780000038007920000000000000000020000000002500000000000000000000000000000000000000000000000000000000000000000000310000000000000000000000000000000000000021000000000000000000000000000000000000000000000000001700000000000009000000000000000000000000000020000000000000000000000000000000000000000000000000002800000000003000000000000000000008000000
SP96Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Alloprevotella;sp. HMT91300001135100013281060000003107290006262810001300057000060000245001025295000000000000029030003005300012700001700000920002140917000140001210100300050000300236110149000041501210700000001534500000004552100003800000012011000000050457026151650330000600050000000013043000000020000001703000000047028136527003330000232004010130000000340201201000400171980107000405916010110000001003680119000035050000396600002725251026000091002430301002491560001140502600680600004000184400005000000000000000000001550706015000254000437400020001100000002880760400000000170108470465500070038710166000000023361401533000073434320000432040000921417500000003101335297440005900006400871625600000000018000000400000002300000800000060084001900003001100000000000034820000000023005321440002912000130013002080000000080005400001440
SP97Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Tannerellaceae;Tannerella;sp. HMT2860012800026044009002109500000000000000157000291014143000761179411100000009800000741200000120020300060150001953000260001900380000150000871100660001509181610017013049100336000606000505117000054000110004300504000000241423140004000001100240213800040141600047090070900070013800000210007000000000000810003824000000000600000110001252806000031614460170040000131409500000900014120700010121900000001700685770000065353461454631104800004138610211560363861990246020904437235132513016230570461049700003499904080035001880048000441713812100212120113076650913120003142943014514329402901415357102010162054008994800152046212914112422752372280102217701606407172020453081944831891369628000485000174030398000000152026131064148000019012043061816045000113501510617735825511038645030070000004713500000206150000095013000004524102040056631200000290000484000140197322004544314000315227480160346871121763000423800377878170012003560570177391100681091371441004650
SP98Bacteria;Firmicutes;Clostridia;Eubacteriales;Peptostreptococcaceae;Peptostreptococcus;stomatis23571114293872301312329058795371195359759612118005252603482902043742467939341315468101132152727014963911121713351813022771121871173106232051189172231909230527946043195048213214198028243114269181118802226501483387720591891375165616411421992800941106931348326953923723207584694193575463080309112221606893312721484343833371853376451372601035500300376831420984524503284820765189311563911517627727171305422192243861573339921006379126914710114691265280050121308793981451511419725520060186860414739152264323815215211011119331502982113171236061386028118785258202832391189470611192360195508574216220718262012915613944552107167433451241004024161237240020325812717987339608604186184454444615472318153143250700826020416160000003800000003954482109001108540115000054000000000000000700000009000030010000000001746000061000065368000001500000290015000000009200040270000230018002350004006102000210000000090000005214300075000000312414713800000027320080000183000080000000000000000000000000000000001227000000039030000000009910000000000001020000000050050201130033451610000300007050000038000000900000
SPN1Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Actinomyces;israelii_nov_96.245%0000000000000000000000000000000000000000000000000000000000000000004800000000000000000000000000000000000000000000000000000000000000000000000000000011827900000000000000000000000000000000000000000000000000000000000000000000000000000230000000000000000000000000000000000000000000000000000000000000000000000000000010424900000000000000000000000000000000000000000000000000000000000000000000000000000136000000000000000000000001380000000000000000000000000000000000000000000000000000039121334820000000000000000000000000000000000000000000000000000000000000000000000000000024000000016000000000000000000000000000000000000000000000000000000000000000000000345262200000000000
SPN100Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Actinomyces;naeslundii_nov_97.813%00000000000000000000000000000000000000000000000000000000000900000000000000000000005000000000000000000000000000001400000000030000000060000000000005000000000000000000000000000000000000062000000000000000000000000000000000013170000006000000000000001200000000000000000000000000000000000000000000000000000000000000000000000000000002762000000000000000000340000000000042000000000000000000000000000000000000000000000155000006240000000000000000000000200000000001000000256963000000000001790000000000000000033630000000000000000009010000000000000000000000000000000000431160000001100000000000000110000003120190000000000006000000000000000001300000023469613800000000000420000000000000
SPN102Bacteria;Actinobacteria;Actinomycetia;Corynebacteriales;Corynebacteriaceae;Corynebacterium;durum_nov_97.904%118630824312001101760101200010000053607809010030000990340192090490201788311105857119088046875000025700002461038220000360186003851000151301320410603023738010558038457915711203715000030013921178601959004323309083440037000022401005100075700004902006074900003500000030433715111000000059130131719469027141427120201526750480506950020219400073285472700474103200012110009236164002405010331728031200010405404370001450019040016710900034121650234160300000312841390260512088709468322613282042387910024010141326013010023728180610181133542154771570140041791161049891191334724357801811645411391582131812518103113085441803090132014005285400609679143577619102933180532860244221400212182631621316210612901179842123126923702694048520372996709261136450021870512271652152436034417500363480342218453259451329650500018258430884106630751557001631484252164371416901198414890032000049776702482689140105458032003964491715486724102010497582053233721531169532511010146263127931671355037401066800050358514425001663090311101951611871879456715701111130481051778133310579601218821479018166013921120697916245249755150011895025631547608320515161089009054644115180142854271884500029093714001088035509099
SPN11Bacteria;Bacteroidetes;Flavobacteriia;Flavobacteriales;Flavobacteriaceae;Capnocytophaga;gingivalis_nov_97.689%0000000000000000000014400000000000000000000000000006003600000023000000036163002550000230008000000000000020000117220000130000021720190005000000000000000000008000000000330000000000000000000005000000340000000000000000008029000000500003600000030000000180004500081700040051500000000070000000090000008117017000000000000000000000000704150000403519020000000000005000000011000018429000000000000000092031120000001016009600000061820010005000273038094276000400138150000000008800003120004000000110577023000230000000000000000000207184184000000453600000000000000500000168000000299100000000000000001631552970000002080070000000722600000086000530002136200000093564300000000036000022000900000001134801730032320000000000000000000793153749000044016031000000
SPN112Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Porphyromonadaceae;Porphyromonas;catoniae_nov_97.342%00000000001201700311000000000010200000000000000003705000030000000000000000000020000000000000001300000000000000000000261080000222000000000000005099000000000000000004000010000000000000000000400000000001020000000000000000046006800000300001400000000002700000000000000360000013170000000000000205130000018000000000000000410000000000000000060026016000000000000440500139990000000000381000000000000000029319340062130000400000000000000000000018000000000000000000000000000001016000000233800000000000000025000000000000000000260041000000000000001900000110000000000062100000000000000001114500000000000000000000000003000000000000000250000020200000000000700703600000124600000000000000222000000000000000001300130000
SPN120Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;jejuni_nov_97.755%007200000000000000066000000000000000004160000000000000000000000001200000000000000000000003210163678001115240000000000000000000000000025000000000000000000000000000000000000000000405000000000000006100000000000000000145000000000000000000000000100000000000000000000000111020336001192090000000000000000000000000080000000000000011000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SPN124Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;parasanguinis_clade_411_nov_97.976%0780611640100040603811000240034000000000005539304300422403171300200012782336001671410127376071192160004682425104217537010570613311100353156000515630000111634514680000611450500001100200001564100000000000040115088402041493225528310038900470221350179022001023221000770081260000021102244061104550006115721417520043930024582120043112511341280121761802770419251269903073007649100585940420181564250000199544221600002492910146000009220000258612020000000000030101792921015710706066701720114300000000000000000000100000000000000000000000000000000000000000080000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002000000000000000000000019000000000000000002000000000000000195000000000000000000000000000030000000000000050000000000000000000000000000004410000000000000000000000000000
SPN129Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Leptotrichiaceae;Pseudoleptotrichia;goodfellowii_nov_90.578%000000000001220000000000000000090000000000000000000025144000000000000000000000000000000001200000000000000002900000000000000027001900000690000000062330243000000020012730790000000000000000000600000000000000000000000000000000000000000000000000007000000002414000000000000000000000000000000000000000000001030000000034000000002000320000000160000000000000000000000210000000000000000000000000000000000000003000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000010000000000000000000000000000000000000000
SPN139Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Actinomyces;sp. HMT175 nov_97.951%0000000000000600400000000000000000000000200000000000000018000000002400000000028000120000090000005000000360037400000000000001046000000030410000000204600001800001000003100002050000000000000871552006300004500000000390000003201300000000000000000000000000000008301657000000000000000045002900746000007000000000420000000001720000000575100002000027000000420000401000000030000000414021307800007600000006594000000469030000015900000000000000017000001292010003083372978191200700000000049299010001345002345800000900000012767051016954000042438383000261462721119000473900011377000037111184800000890044600015000000175923571040590200009400000000572239700006750190000791600180000400000013130000003800010212132898344340001350000000025600000160757810525073800000000057000405911490000013028160005523024221213000001710001839280000291163500000375
SPN140Bacteria;Proteobacteria;Betaproteobacteria;Neisseriales;Neisseriaceae;Kingella;oralis_nov_97.741%000300004000000000002700000000020000000000006000060010000300030000000260900000005000000000000060006300000045030515280002502100000000400004000020000000000000027500200000120000000000000000000000000000000000000004220000002000000004000000000300000000000000000000000005000000000800603000440000000000000000000700000000000000137000700001507050099000000013668003600000000070000029006820090000480012000107015023000000050320000007000000200000001600005050070750240181362066000600521500214190060015332700031000000000000043218180005000000000000000000000000000000001800000000050500000002800009000214000000030500000006000000000000000001100000057016002042564000094572000040600000001600023101600000000000084100015000
SPN150Bacteria;Firmicutes;Clostridia;Eubacteriales;Lachnospiraceae;Lachnospiraceae_[G-2];bacterium HMT088 nov_92.887%1400090000002900000100140027001400000000001300000210000000034000700000000000000000018121601201300000033120000531510009008016000120000000031000021070091225000000030594017900000019481051190000014000000000000000000000000110042400000000012000000060000000000050000000600000000061380000941700220000000000000800667800010000000002700001700000142000000007381316000000009002300000000000000000010000000000080005000000000000001600000000000000000000000000000000000000000000000000120000000000000000000000900000000000140000008000000000000000000000000000000000000000000000000000000000000000044000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SPN157Bacteria;Proteobacteria;Epsilonproteobacteria;Campylobacterales;Campylobacteraceae;Campylobacter;concisus_nov_97.403%046000000000060000001205069244897000080330210000000000004002200000008280401214360000003100615608000001000922510004342000530000143000000000000000000000504007300000844029000025000080000270000600000000000300001808000277240401702406571400000000000000530000000008310006284600000010003172080000062813414990001909000014000018100000000000000000000731400001100000216929640000205000015000000000000000000000000000007000004000000604800000000000000000000000000000000000000000000000000050000200000000060000000000000000000000000000000000000000000000000000000000000000000000000000000000023000600000000000000000000000000000000000000400000000000000080180230000000000005000000000000000000000000000000000000000000000000000
SPN163Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Leptotrichiaceae;Leptotrichia;sp. HMT215 nov_97.397%000000000000050370000000000000000000000000000000009000000000000000000000000400000000000000000000000000000000000000434004500029503300000000000000000000461300000000000000044000000000000000000000000036000000000000000000000000000000000900000900031027000000000000000000000000000000000000021003210000000000000000000000051200521000000000000000000000801719117105000000000000018000000000000001400009400000000000000000007000012500440000000000000000000000000000000000000009700003051344000000000000000000928610000000000000000714000006000096400000000000001600000000000000270000000000000000008000001200002322000000000000000000000000000000000000000002170000431200000000000000000130013900000000000
SPN172Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;veroralis_nov_97.342%000000000000140000013017026000000000020000000000000020000020104205000520000000000000009915400000000016700000000150000000128000000801400553213000280000000010000000000000060000110008000000000000082000014028736000000000000000000000000100000310250183400000000000000000226456000000013700000000210000000971100900414070081911500011500000000900000000000312110000300011000000000000002000028020000000000000000000000000000000000001400000000000000000090000000000056400000000140000000800000000000001000000000000000000000000000000000000000000000000000053000033021000000000005000000000000020000000000000000000000000000900000000000000000000000000000000000000000041931300000000000000000000000001200000000000
SPN179Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Leptotrichiaceae;Leptotrichia;sp. HMT215 nov_96.963%0000000000006400570000000223811550000000000000000000000000000310000000000000000000000000000000000092000000000000000022000000000000050647016000000000000000000000540000000028200000000000031079000000044384147174000000000000000000000000000000000000000000000000000000000600000099000000000000000090000000000000544850080000000000000000010000000000000320000000000001910000000000719650000000000000000000000000000000000000000000000000000000000000000300000000000000000000000000000007327800000000000000000000007000000003000000000000190000000000008742000000000000000000000000000000000000000000000000000000000000000000000000000000000140000000000000037400000000000000000000000000000000
SPN18Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Porphyromonadaceae;Porphyromonas;catoniae_nov_97.951%004400000000931118804644001300051851015000013000000000000030304010240000006030031000000002300000000000000120010000045000002400000160000870000000086212000000000001000000000320000800390120060000000005005000000000011000005400000000000000000120510000270100051000100001400010700000000000000000800000220000035014007000000300600010000010000000000000011000090014000027010710000199291102713103135115410000009420370140000000014803290000045000484433339340027160000050000000000000160000000000022800903720001080004700008000008260000003462165801321500000000000000000140104061001000180180000227006100000009700000000001100000561900003169000000000110000000100000190000000000000100000000000008600000086000000000790000000000057000001760000000000000000000001019800000
SPN186Bacteria;Firmicutes;Negativicutes;Selenomonadales;Selenomonadaceae;Selenomonas;sp. HMT137 nov_95.842%00000000000000005000000000044400000000000000000000011500000000000000000000400000000000000000000000000000000000000827000015000000000000425000000000000038000000201600000000000000000000000000000070000000000040000000000000000070000000000000000000000007000000000000000000000000000000000000000000000040900000000003001080000008015000000000000000000115001600000004101000000000001400000000003415000000000000000000001000040000008300000000000000000000000000058060000091000000000030720000000000130016800016000225000000000000000008210800000000022870000000000000000000000000000000000000000042040000000000149000000027000000000000000000300000004400000000004317530000000000300220000000401200
SPN197Bacteria;Firmicutes;Negativicutes;Selenomonadales;Selenomonadaceae;Selenomonas;flueggei_nov_97.822%860000000000030600000000000010000000000000000000000001000000000000000000000000000000000000000000000000000000000001300520000000000000000000000000000009000000400280020000013000000001000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001800000000000000010070001600752500014000000060141000000000000101178000000800000430000000000000004100000000000000001270330000000002900008000080000000000000011006830030000000018740000017000164000000097010510131015060300761120031111005000000000000000000082000000600000070000000000800044090000000000000223400000190000077010013000000000000000000000001017161600000057140000510270620000000000034079000000
SPN211Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Actinomyces;sp. HMT169 nov_97.992%000000000000000000000000000000210000001200002200008000091000070350000000800270000073000000000110000000000100000000000000033000000180000000000700002210000000000000000000000000000000000000000000000000000400002700001300000003109000002106400000000006000009000000000070000056000058350000070000000000000038000000000050000020100000012170000120000000000000000000000000000000000000018100003100000164000015001702771000000223043000000008900000104000000000000001053000001666270000011000000010900000090010004003260000143027200000000181005000000000000001000000000000000000000000052004103440000643000071002605336460000094700000000001120000046000000000004400003259600009506451000001140000000600000001600000000711100001360133000000392013520000000000
SPN222Bacteria;Actinobacteria;Actinomycetia;Corynebacteriales;Corynebacteriaceae;Corynebacterium;matruchotii_nov_97.331%000000000000000000020033000000000000000016160000001200370000000000000000659000000000000010000000000006900000000016000000000001457200000000000000000000000000000000069000000100000000000000000000001090220000000000000000735170000021000000000000000000039600000000000000000000471400000000000001630000000000314900000000000000000000000000000000000000000000000000054980000000007100143000000000000000062720550000328043830011504000061000000000022300058600000000170067900000071164700046700000000000000000000941116640009000000000000000000000000000010970000000000000000080000000000121705220000000000000000233517490000650910009100000000000000002964000000000008901135000000295194800000000000001900000000000014622680011140000000000000000000000000000394000000000
SPN27Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Actinomyces;sp. HMT175 nov_97.755%00000000000013000000000000000000000000000000000000000005000000070000000000000000000000000000000000000000000000000003900024000000000000000000000000000000024000040000000000000020000001100400000000000000000000000000000000000000000000000002000000000000000000022000000000000100000000016000170000000000000000000000000000005250100000000000000122410064500004700002320000000000000015100000000000046182017259000000000000000000000000000000000000000000000000528773000016000000111140000000000000001380000000000000289299680003400000000000000450000000005000000000000000294000000000000440000000000000002400000110000000000000031000030870240000000000177000370000170002210000000000000001970000000000000016439000600
SPN304Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Leptotrichiaceae;Streptobacillus;notomytis_nov_93.856%1618003501800001493510317000150010301095153581045014050064164009898121000814200572081702700000026090400000003412401113434101355622410310113630273962207592200105002940000081010600041052643203260840921016189149710580851001107152601392000029024116110545226098001802020015000620500003621009000000150026650000116700028023000604570090000380060000000241100000004170725919223010470831005070250054100430039320000049078000000110372111408320351938288130000000424241628400000001426400388000070000000000000712002900000013070014000000040000001100000000000700000030000000000007000000800000180000000000000800000000000001100000012000173000700090050000000000100000000000000000000000014000000000000000000000000000000000000000000000000000000000900000000000000000000000000000000009000000500000005000000000000680000000000000000000
SPN31Bacteria;Bacteroidetes;Flavobacteriia;Flavobacteriales;Flavobacteriaceae;Capnocytophaga;gingivalis_nov_90.546%6700001050003528206480000270007116515000003000000013223000304000841000001051503000045060270000246120000471810817123983927500805200950014300000000297003720062000282726353163800990251006873000006210121047310008288007000911050000300000004700000221000281579140040579000743600051340000000032004501500000015700000157900127410048120000355000007060300000916000303180000891720150000463000011000000405420000014038000622100124840830016108782143200006300020102724100125018900013003652800014300107019339000000500000579270004000350200001728788837658517321583521200750400060022084000000007400904134006000260744155313314009100194003935150000016389037230623060395244000005274185047004622647900300000012802156001218122365000011387000178601701822800070000186001692520404000035000000084502325329177416708127008030000003852000000000000008000056905215970470211004706200000090900000000107700
SPN317Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Alloprevotella;sp. HMT914 nov_97.347%00026172583600212172728244933530000039556562329021844115301136180210617004952170000019942231816002409174207413702501130605250037158043320342188278184380190028524700119381122280584503222151211000000319010040149933120225295328827671798614386400954269348129004911497033900000035439410000320160471000071943585000003102292497500000982423123821085305713118190013215109015300023065014332180030013612034653180236562780602850042002822482167209371650069528112916110217991201160069045352150120004066510000007390252791355416396806430564190288418138350001754134149266000002171101591900000110391580300000000000000081451300100071851001304000008600000000001001080000000000000000000000809000030017350000481000190000232400000000000000000460000801016036139440047020225060000000900000000011090000000000000000000000001122130000000014800000000012303000220000037000000160000000000000460000000800003000000000000000000003200290902300080002000067014280000500900000009000
SPN37Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Porphyromonadaceae;Porphyromonas;catoniae_nov_97.536%7450000000000000015282500000000011101000206010001571380000001000100000000000004200000000000000001000001800013400000000000100000000000000520000010000010100000000003000002008910000000000000001300000000030000000340000000243900000000000000000000011000100010000000000060000000000100000000000000000000000000430000000001000100000001000000000050062041000000000000026693430000000288000000027000003073287520000000000000000030041300000000200070000000000000100001400065290000000000000000000000000000000011000000000010000000000227800000000000000348100000000030000000200000021361931000000000000000000013900000000130000000000130000000000000025230000000000000000000000000000000000000000000000000000000
SPN404Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Actinomyces;sp. HMT175 nov_97.746%00000000000000000141957670000000560210000150000013100060340006000000000040000810000000000230000000001000001814000000000010200060590000164900000000514000000000000000000000000000000090000000000000025591561131790000016254060008700000321300140600000000000000230000330000600100025700150000000007900900000000160036000782000000160000000141000000000000000000060000000000000000000350000006921637022500000001823293630004230100029002930750128049200001204100024000050000040100221419901240000001300000642100000000001810003241880000137718300000000594400000000015000000000000000031000318000000027900000191525125055838420000000317814181204800013014000011888006235106046000000042100000760000000002000159003372843360260000100010638620067116800000002350037800017051463000053112200000100101440000000000000135000018680000000250
SPN413Bacteria;Proteobacteria;Gammaproteobacteria;Cardiobacteriales;Cardiobacteriaceae;Cardiobacterium;hominis_nov_97.510%000600006500300050050000000000000003000006000004000000060020030000001700000304000000000000000018100076712006000104900000310000000100000000006004000000000141600000001300400000000000000000002500200000000000000000000220000000000030000000000000000003000000004000000005110000130002200140060000020000000000000000000000030000054106071030900170000000268560030002550013001761202456200091550007269000654870162000720868000029000600150002857000000026210356100010068512300500003421722700343771041110613114710567902990000815100000270374045046000723001312401400000622471171108231439735012013410400000000232800170741626800000221001813000236600240700460059600000736000061000008000013640000000948516601860577008718020000211043200004940012013941326290381000001970000030970184014804720049450076017016000000214010900365352119044480230
SPN44Bacteria;Saccharibacteria_(TM7);Saccharibacteria_(TM7)_[C-1];Saccharibacteria_(TM7)_[O-1];Saccharibacteria_(TM7)_[F-1];Saccharibacteria_(TM7)_[G-1];bacterium HMT347 nov_95.759%000000000001200000000001900000000000001200200000000110019780000000002556000062000018290017000018000008220015011015000000163900000016000000000002200000018001800000000000000600000002400000015200000000000000000130000110002039000000000000000008800000000000000000000000000000000000000000000970000002010000021000000000000000000000000000026000000000000000001990000006211902901400000110000001680042009350120700002300129001122130077004123032000000042180190051270009395184334000012714041000104001790004401000142341246000022011300000009000139044036400180900143555000000000000000003800000016514000000000000000003700140900006200000002403825670000020500003200000000042000000005930000000000610000001600029300005060177402600890000002100000000000000740000017482000000000000000020200
SPN506Bacteria;Bacteroidetes;Flavobacteriia;Flavobacteriales;Flavobacteriaceae;Capnocytophaga;gingivalis_nov_96.218%000210120001229068014060005500000017100504000110080120000003342100000000000101809667119818001160007000024000921000002216015150000000000388801601200134903407080713365074811405007800000000067012000072012038000007000300150320600000068001970065033000000002000000018700000000000000007023130003100008000160107202200000384300000002005900651502077000091503600000017010429600000000000006600562600110260100000237116015901261012269263242200052102600990949002642540005300194154000004007818001300000004601811880041130001796800960002212902384810729500744330930200000002200109597526210001029152383802703203663002155098619695003612290530000000251931671800017503223008500001612401502200147353249332012000736060062492003807200000001400000000452200080000040445173870001028050027620900530002518106833051370240110755330198125800000000005600130000130011010814017032321240492890835190635001009837000000018001106701100154038
SPN519Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;sp. HMT305 nov_93.865%1313081141424021875055201368872850530086895977100142833024311277124017142200001593243448127124088538638064046495141615702715214301434103320438340085103431991344140571807573631009242070300000000248002107681751960197917967105262103023313611317491166655218106922819147149130271005056210522335001441011935213490116832325400420010771112351010104383160162502109950736000004166715382010842831040015160030192085008666000574126482412249513592511115412098514550555819817007143714824000000245917238612715691646447620905913016005735015158377422530454841021811180149683701000085110780990000000000000000000000001000080000000000500000000000500001010000000000000000000000000000000000400000000190000000000000000000000000000000003500000560020000001200020000000000000000000000000000000000000000000000000020000000000003000000019000100000000000000000000000000000000000000000000000000000010000000000000000000000000000000
SPN54Bacteria;Firmicutes;Negativicutes;Selenomonadales;Selenomonadaceae;Selenomonas;sp. HMT137 nov_97.228%14103000000500000000000100600000000000000000000000000023000000060000000000010000000000000000008002000220000050000600000000000000000000000000000000002000000000000000360000000000000000002400000000080000000000500000000000000000400000000000000000000000000600000000000000010034031213000000000000000000000000000000000000000000000000026562500730052000000000150280280000000150192300010100335413002536003715000036100480460000000000037101200000000015630048002174001500000536595731160000000000000000000000000000000000000000000000017069508000002346200000000000280350000000100622000158000467400012520018116000000018270000000000401111000000000002330014304213000000003001731227395990000000000000000000000000000000000000000000000580
SPN563Bacteria;Actinobacteria;Actinomycetia;Corynebacteriales;Corynebacteriaceae;Corynebacterium;matruchotii_nov_97.967%00000000000000013015000000000000001800000000000000000000000000195000000000220000000000000000000000000006600000000000000000000000000001854000000000000000020000000000021075000000000000000130000000000000000104000000000000000000000000004640000000000000000000000000000000004002400000000000000000000000000003400000000000000000000000000005000000000000000000834271217000001163201034100000850004300000000000000000000000629000000001086215800000000000000000000000296000222100000000000000000000000000004007100100000000000000026000000000001034090200000000000000071519421300000516006620000010441902300000000000000000000000558000000000573000000000000000000000000000336000000000000000000000000000014192750000000000000000000000000039401642
SPN576Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Schaalia;sp. HMT180 nov_97.925%0000630000000007000000000000000036720434000000035694350000000000000000000000000000000000000000000000064058000000000000000000000000000000000000094687450000000000000000000000000000047200000000032000000000000000015641935300000001370430000000000000000000000000000000000000000000000011508300000000000000452000000000000000000000035791107122000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007000000000000000000000000000
SPN588Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Alloprevotella;sp. HMT308 nov_97.347%14000311821900206335355000000044145126800000882816000000035013149821912231638200109480004634522528400603007202510871133505635045710001230044400950000000280030000000000023500705320008300000000040744700000002200900005201301006050000293515809173638500000006179600000042112921006200405124521281400025421425500211610004399710747200000002501480167416009513461380071330000016000000391491100250000000000507800507770400016700000430000017101900000020002400320830348147000000000000001600000000340000000000000000000000000000000000000200000000000000009015000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001300000000000000000018000000050000000000004708000050000001100000000000009000000000000000000000000000000000000000000000000000000000000
SPN59Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;sanguinis_nov_97.782%124610000380000114676000023600361110000000000000410000016000000000001160000000000000000624000000000310000000010060000002767000000000031000055413294006590350002850062000000000006011502200000000000003043400027510000002100002100121400000000000001620000025187700000000085300000000000000037000000000270000000017300000015750000025000020000024832171001220127910038001130000055500000332027105160002200000000103451526001055000005026581200005120066850000000000000153000002734190000000002270900000000000000016490000000007700000000490102600000627645000001500008980000155143394900281401638000172800161000000000012301979027010000000000004192637890034191000010888410000600004061000000000000059700000324167198000015000028682199000000000000000247500000000010800006000511072140000044113100000850000340601214073416827600908030313080057900192200004020000070730243603550000305400000003205
SPN596Bacteria;Proteobacteria;Gammaproteobacteria;Pseudomonadales;Moraxellaceae;Moraxella;oblonga_nov_93.776%00000000000038440133351001800002684743715300130000000000150000000004212130000000000000007000088000000163030000001060000024004000016600000000001032000770023120008687545273473635800000002030832118380000000622340162018270008860000007500000001503502000000020226921531258000010306000000000001000000000000000000000000000058000000200301490601300000000000383000026000000000005762000141281530970000000019004300000005100004000151000000000000006386012186486003440002601091884006430000000013050000000008781000000000000000004001500000011948059100005827000000038000000000000001776000310172000035011141344925934360000001190635252375000000033213201427210339007270600000028100000001230000000000117023107800001490000000000000000000000000000000000000000057000000023000000016000000000007500007600000000000108400004241890170000000400700000001900004000700
SPN597Bacteria;Firmicutes;Clostridia;Eubacteriales;Lachnospiraceae;Lacrimispora;xylanolytica_nov_88.613%0000000000000000000180000000690000000000000000000000001270000000000009103870800012000000007000000000870049000000000000000000280000000000000000132000008000000201140000001101604500000000000060000000008000013000000000000400007000000194000000000000001701000000000400080000000006800007000220000080000000000000000800000034000000000009093001819010003300000057000000050000002850022000018510000000000441140000000000000003800001600002600540008400008320120690087507240015456290088400000000000236000004835000000185501100001640014094017000013101427709719835073072038300004790000001111170000000024902270048000024800000098000015100000074000000900001521056048000354556900007109000101094000094000028000980000093000000181400153700014003603906680055093012600006014200106239002204905
SPN60Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Porphyromonadaceae;Porphyromonas;catoniae_nov_97.746%0000000000231410000000600000321400000000000000000000000343800000000000000700001050000000000000000000160000000000000000000000000014000350000000000000000000000000000000000800001000000000000000000000190000011200000000000000009200000000012000001800001000270000000000000000000000000000000000000000001400004800000000000000000006000000005900000000000000071229000000027000010639613000000244300000000000000001993500000000000000180000460092000000000000000053800000000044000000060000000410000325000000000000000000000000000000000160000000000080000000000047001930000004700000000000000009230000000000000000000000015600000000000000003400000000600000000000000002591800051000000000000000000070000007408000000
SPN605Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Fusobacteriaceae;Fusobacterium;hwasookii_nov_97.783%11970013000000668700400472424008700911475380001280008150000206402300340045128303244000003900350000000000147382640471010041230343000004901305801649007419000065028000000401400650005125493900033133005455470876000000015983932658289000149005600031000000025004100870001907325100006800003300000100000000004000000000008250000000285531517175078300091001500000519100027802751600002702000000403700985600005855000000027260114134000000055700017720560000000000000002200088007000000001700000000000000000000000000200000002100000000000000000000000300000018000000000000000000000000000000000000000000000000000000000000000031000000000000000004200000000000065000000000000000000000000000000000000000000000000000800000000000000000000000000000000000000000000000000000850000000000000000000
SPN70Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Actinomyces;israelii_nov_94.882%0000000000426000000000000000000000000000000000000000000000000000000880000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000830000000000000000000011000000000000000000000000000000000000000000000000000000000000003000000000000000015220974000000000000000000000000000000000033400000000000000000001550000000000000000000062000000000000000000170000000000000000000000000000000000000000003912800000000000130000436224300000000000000000000000000000000002200006800000000000000160000000000000000001000248000000000000000000000000000000000000000000000000000000000000351000000
SPN73Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Actinomyces;israelii_nov_97.410%0000000000000000000000000000000000000000000000000000000000000000005747000001800000000000000000000003600000000000000000000000000000000000000000000000130000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001800080000000000000000000000000000000000000000000000000000000012000000000000000000000000000020000000000000000004800046000000000009000027100000000000214700000022000000000610003684327000000442000000000000000000000000000000000000000000000092000000000016000000000000000004300000000000000000200000000000000000000000000000000001420000034000000000533900157180000000000000000000000000000000000000000000000000000002200000000002600
SPN84Bacteria;Proteobacteria;Betaproteobacteria;Neisseriales;Neisseriaceae;Neisseria;sp. HMT018 nov_97.942%00000000000217000000000000000000000000001000000000000000000000000000000000000000000000000000000000000000004000000010100000000000000000030300000000000000000000000000000000000000500000000000000000000000000110000000000000000000000000000000000000000000000000000000000000000000000005900000000000000000005900000000000000000000000000000000000000000000000000000000000000006700000000000000000000000007800000000000000000000000000000000000000000000001030000000000000000069813100000000000000000000000000000000000007000000000000000000000000006770000000000000000000000012200000000000000000000000000000000000000000000000125900000000000000001210956080000000000000000000000000
SPN94Bacteria;Bacteroidetes;Flavobacteriia;Flavobacteriales;Flavobacteriaceae;Capnocytophaga;sp. HMT863 nov_97.890%0000000000000000000056000000064000000000013060000000089000000038000120518000000006000000000000000000000000000000007801400000000000000000000000000000000000000000080019000000000000000000000000000000640000004060400043000000120000000000000050000000000000000000004170000000000300000000680690000000000000000000000000000000000000000040079000000000000000000000090000000106700000080470297889011000000683660000000146200151400003300000000009000000104900000000000000000005000000000022000000000000000000000000000000019000207000000000000000000000000000000552000000001203223002030000001100000000603900121113000000000000001200000098600000000000000000001690169000000000000000000000000000000000000000570001900
SPP11Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Fusobacteriaceae;Fusobacterium;multispecies_spp11_21338936302902035301568693012292463136501503596006550102111000202802002929004523032101003224090016237890220018190431816100121751170256100149157261001132778423388003414540063110181535222512021044101319065401232201811261001010287068182401323510016127771240150001002702436003824001102869200078114160031210020100110229360011000000783010001622140450301420312252222056062154223176150461293000771712035156018168001292923540522525001282462316290088130372937605980073336339017292047205454034700110009000101049011009418296800000001000909790002000500000191000020000011506900140001357009000933151700000700003801100315000151900110023018630100101000001300240230021000011640000800320000001323100058000091328310000101000311050502802800031000010200017300003009000002145000150000400012007000000000010000000550152001217000037001008000003341200000000700170083027001011300005711093300000193231930001745000000
SPP18Bacteria;Firmicutes;Clostridia;Eubacteriales;Lachnospiraceae;Oribacterium;multispecies_spp18_263564878422094281399632552874398153931271371723299194738818916849268179252106111701203233702522190424216301271281003541114156019123828124172141627149218385443959013919102754313305136084115211020641483711651733651777321811513259887566040156460152957461839026511339073523914738193581581371479991137136455410524682711211125985113811798732914783002693791743901903641580769659152226117452452971652573132623229541511533223661074811408251212062691624185373071611971801322306935197729992001712111460360582141702395216571471651330417223170211102711486652021761983041412335898187382321307205123152176012991702236936461088061325326481117857291227943300165619175341001391432352715910055241156134527182278301027287732101239616828612783277410424155431788005891751012140400000000000503000000000000000000000000000000021000003035000000000000000000000000000000000000000000017000000000000000000000000000000000000000000008000000000000000000000000000040000000000000004000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SPP2Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;multispecies_spp2_31653615127771234126552340040837326862760236015429690001172082561923955855495498015101847502260462100834692341741850179002386270203064873309816048860260133053126312258181349118137350125132410976101890336690542151710152283215446095040105918113803202029203005915326327459077018486619235448145112314126122641211271222842029101120190563490082634840303312740131843428106071124001031931333195645012704613313500021160166524250136044022891325525140203160693115082306982012680009956222041388321078850171771352852317001023765422923095305758244502380140190304125833366191004900152176010111909182011106843622200525719118413003819121026725493041933035497145242135414136213226236836223478029100017641388703614363711570000000000240000002615000037026000000120010000000000920820054000000002600000000000320001401200000000001320180000000000005800000002000000000000000000000000012017116733130090000101000033401200000000000000701900200000000000000360000000003500027600000000000000000000000000000160000000000280053000000001900000000000000000104000000000000000002401214166696750000000005015102300
SPP3Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;multispecies_spp3_30000054000250000000004802200000380360000000000000000000000000000000001480000000001603300167000000000000000000000002300000043000000000007312408656000000000000002100000913658364032111002692723600000004130004100000000090000000000000033000000000000000000000000000013000000000113000000000000000006000000003502130000010000000000000341751361458500000000000000900000267422627077498003440980000000000000000000000000000000000000000000000000000000000000000000000000000000090000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SPP34Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;multispecies_spp34_2000000000000000000000000131700000000000000000000000000000011000000000000000000000000000000000000000000169000000000000000552102200000033000000000500000000000000000000000000000000000001200000000380000000000000000000000000000000000000000000000002000000000000000000000000034000000000700000280000000000000800043020000000000000000000000000000000000000015500000004370120000000000000000000090000000011000000000000000000000000200000000000000000016501240000000000000157878015200000000163000000000220000000000000000000000000000000000022000000102226012280000000000000000000000000000000000000000000000000000000000000000000000000600000000000004662583700000000000000029500000000000000000000000
SPP39Bacteria;Proteobacteria;Gammaproteobacteria;Pasteurellales;Pasteurellaceae;Haemophilus;multispecies_spp39_200005200000142407400000100000024600344008000000000900005004226782013021280000490070000000029408912190065128297000090000292900590010000000020300011801180103450002313700008100065023360000112692164000003381300000000000000032000000000004002290000000000110000007700232300007285000000047000000022213420360003613145444000002800900490016000001018000703804220006760005680026006500310018530000000169030305206400000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000580000000000000000000000000000000000000000000000120000006000000000000000000
SPP4Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;multispecies_spp4_24221075751848683111517670583312035641013693701686721286105341114210451187423352171275086310341553117391763617829933467636631620134127774310401993102503501196177264514441214767838891130611533802412831763121261026209382099977127383852516829401525120443101481602789104813843213112021431555443396361112141920585628752904100576859765104466212721720687632300160510641454125837503831431907784565178639312781945267141955159849416999211670270110670103213918188563584881029459171541801188773105754641048471162266695268021121276257493144866518178565924823171344342225133695176714554039529907001744265213771427158612168910291879783071801156361740482764726183381849456743592838161245534186460741306166128923941472256314661637674475251445539203826331719697317912207261191611917121067688267249235328540775480295346658488095274373436902454498806532789623904713066592655158327921511058265920302977517800181425760882277173619214028328961330608253511121181515021680344110410591318970242100239079325672072722392765829850816918690715765023608012378143580211720001950157313008006465748620271388008465000327228700066570379371136424651417483300070060017028301505674300350655022152241000032829670015109033111000139228618301630005104410133201101020363808905361113000247555003180000011119032352189088415646237531150981111222538000002134483762135304919090010220112001728617901714232429610212302167984310476167143331617163000254824200520254611720120483870238301603015120052007547809213320800001871130268170708114251380341680240000729413715342913091813144237000174486856147360000820695123
SPP42Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Tannerellaceae;Tannerella;multispecies_spp42_28033060000000000000000000000000000003000000000000000001400604160000900027015700000000000000000018002000015005717000000000016891000041000250000010022152700300100002011162600000000000327060000600000000050900000014001500060120000000000000061700001740000000000000000000000000000240500200000301014000000190002775170000024000000000200120000100000417002214000000121000598505004000021106004200000518003310800088115701100000100001000000000020417924280540631160752300119291420018255000700550000000004355036320245906590086163209001813300000963225000018705214301486103512627027111200246017107100000072143600000000310067878051325000000000000230501960000176901400090000011000000000800200100270070000114351100850039000000220000004925100004661200000305500127142012000042000024807393659310047310806500374103356500000025000000001300
SPP43Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;multispecies_spp43_2000000000000000000068000000000000000911043000000000000014377000000000000000000000000000000203000950000084000000000000000000000010709900000000071100164920001640620000000000000000003800000000000000000000000000000000000969640000000015800002560000000000000000000000000000000117000000000000000000000000000000001430630000000000000202300057000000000000000000000000000000000000000000000000000000000140000000000000740000000000000000000000000000001800000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000670000000000000500000000000000000000000000000000000000000000000000000000000000000000000000000001300000000000000000000000000
SPP47Bacteria;Firmicutes;Clostridia;Eubacteriales;Lachnospiraceae;Lachnoanaerobaculum;multispecies_spp47_2000000031006432360631000700741693401600033028800200002413006018013403412019001301132120082220000900000004901900530030005902930044335023928100120070006023445221000190000000026130192772010291613100037181600013300000003760002400020069840180625000001035353329203200070230000000270000028039811138401403902220017048000002148000837016183600330521300000780860007213201436000080502968000002300600001006100211722121818220002420000027090000000000005416000711231072437712400000194043360590000144719004037100256000000000025075306121022018200000001900270002070068000054001500000011374220024161701600550000000267980000120000029000005384212000240213081521140090000003351000000000006142120281020011003700230128006760118350009935341390630000500401100000001730000130000000130017000140000001127390000040000066000000230000000037000000000000000023420400007404500000000043020002712
SPP50Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;multispecies_spp50_21151686972867309992608743373162176024507283119201170191558535832331177207194331438428586431905937384014363249564542131525631109213155397143188322074760113909111215290111000181144284240611222330582879162646178533143331691883921251119761582224383096110671543801355254631721611282242122341047703103806729259001287112133841421409625245545704113093178101273471173273794107849106066149543130747159082782271217124474068821211480121737514101807892815632900232250014965951078429414985701652702030884571031116351129318889228215135338597522745957222810768155439668330691996725959620027951220873422968868337410931733216331227253631952861475847612521911371014515510783635683111098274449123398413665211034492511371318971742926481769077820621336265234605007404056756792825682515551096322666633241184329699197000000000000000000001200001000000000000000039000000000000000000000002500000000000000000000000000000000000000000000000000001000000000000000000000000000000000000000000000000000000023020000000000000000000000000000000000000000000000000000000000000000000000000000000000000005000000000000000000000000000000000000000000000000
SPP59Bacteria;Firmicutes;Negativicutes;Veillonellales;Veillonellaceae;Veillonella;multispecies_spp59_2941299172443173391534251811749729752456523636884788315059917159474740142633259390122352545437782874471077411741194215638578373294841140818343714825339239768026530635595739126854240741147871861276282813419228711955907718913958574043553040391037781628318010216221058191289481024568493984707523208549913416610138119212031390349056748510112391351341589025124856272712111924856856027208217017110826342014326813363231785188715244831160937556273449727722367130566110387203003079286432930735654073169512032821571209580505035225731744819535087442121338043121311783921706707389091470865182222185300117137918176553871462341661755707451305479912156125943479186342246572167255520919144974930726648579812314868342577081515299106921871942127674106930112859751464575391344838910076677642068983025315641163542399046295057792612739402162376113643817512104128486259893655413976954713920094738484897164954761276523845642731378216233431774158525622386119448893327564322748435380134139061579531392141103646332831920166811812834519176076023131834514578278513241096767282321714424161937118613381778160838071290329376532511127110996176449145914457430156824239552831117296614365933161821137176614519063136313141147812316920131145202405783065602971893074156830153534857128107140852780470237899040851701523348811667351121568127473251072939769317192242201291389001132149279313767412684420042611274463231681434269386907523489258311461807382998431506293451966491389904118045128086412161985687324272109172527921632987891171331084561136710424551101129592511910732415510387467649117918460168514351136192293995710873138563629096715391892623230747915234441503408199037927216977036150599805514255280741149934193167148843415981793501242138961332291372072012139687752271219963991941382156119155002133530135529192713563701183303333833977255120151428632562240837549398214721104561
SPP6Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;multispecies_spp6_20000000000000000000123000000000018500000000000000000277000000000000000000000009500000076000000025717119074600200000000000000000382480000000000000000000000000000000000000000005300000000000000000000029000000000000000000000000000000000000000000000000043004500000001880000000360001720020001100000000000000108000001800000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SPP60Bacteria;Firmicutes;Negativicutes;Veillonellales;Veillonellaceae;Veillonella;multispecies_spp60_302691222418708385922076251651539167091291154084676537088209741400107003476652448337222418647168131209772814989938836382827302742821174182666029870142403114025698093912706681492728290063617696213710247741844524758045220113912848523117554885164127136453194308573900808565466591149514112710996576560706398016147038478428160408142003873249019810171014803041661000022833715883725913446665468472239558372325895973080119931164367019719222694149041120105411117141591112962416504712110000060954233003275519405183613393302211257389232529494481022721480140639245957118896178123524559579582404504102779015841425745731331251261175400531126072300431231522502336827728965035628519247418006113477497661399576832277311073880491137803138171564668509013311110020859712653485112024175010311024000081253331644586173171243119556426166210689463853889455500000150000148000000000000000000000000000000000000000000000001202800000000000000000000006000000000000000000090000000000000000104000000000000000390000000000000000000000000000001600000000003000000000000000000000000000000011000000000000000000000000000000310000000000000000009000000000000000022000000170000000000000000000000000000
SPP62Bacteria;Firmicutes;Negativicutes;Veillonellales;Veillonellaceae;Veillonella;multispecies_spp62_20203501025811160000105304200089103200071071051154004021363903153062070312110000700008933247000000004365131623650200013001150016810905762390282492661000303700012139300000030015110981855010111441172210705053100007319122000019120116116000102001400042113100001610190152002201726000106023000400010001013060072019800010340132466623641050003603010337429016952089263071401420640027448564200465029164525072711031613401231161106240001164123075000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SPP9Bacteria;Bacteroidetes;Flavobacteriia;Flavobacteriales;Flavobacteriaceae;Capnocytophaga;multispecies_spp9_2000000000000390200000000000000000000000000000000000003614900000011000000080120000000011000000000000000000000000008000000000000000000001300000008220000000000000000000000000000000000000000000000000000000000000000000000000000227000000016000000478900000000000000000000000000000000000150000000000000000000000000000170000000000000000000000000000000126000590005400000025035800000000001190001000000036002494200210003200080000120680000106025000000000000000000000000000003631400000000000000900235542280000835900000025000001200000000000000000000003306009200000000000000000000030000000000000950073000253220000005913710001748900323000004580000000000000000000089000000000000000001829009266000000000000180000000000000000
SPPN13Bacteria;Firmicutes;Tissierellia;Tissierellales;Peptoniphilaceae;Parvimonas;multispecies_sppn13_2_nov_96.842%000003100000018082041270000000774301284752353368027140000940296214000000013602110051078011000621303403904089501000136021318000003400031060009340000162002560000000000001900820220002412404625045456101162536617100963911881290000001451407000000030343125000115146009000005116156000000397423327209119000000000017517804000000000002822441500073700032733092012700793050018000000137816064240000000001580553820000000000003050100032000921300352340060282110029053024926600000200103310000000158011000000000000000000000004060000000000000000000000000004000000000000000000000000000000000000000000000000000000000008000000000000000040001000000000000000000000007000000000000000500000002000000000000000000000000000000000000000200000000000000000000000000000000000000000000000000000200000000000000000000000000000000000000
SPPN28Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;multispecies_sppn28_2_nov_97.773%0161001140157369147623954860000002130000443000300111939516002570000000351208300010800095456107005000005100018000910040110027000000002116300840004000008600002000000007811300000000000000000098661379126900000000000000708005002418115761294200044000408003270171503104490190142492008800000003600130051221400124654351005610500003810811270139000199480000000000000001941500297008000000928000001500000001519000000075300000000001532272482574058000000000009000000005005000000000000000000000000000000000000000000000000000000000000000000000007000000000000000000000000000000000001200000000000000000000000000000000000000000000000000000000002000000000000000000000000000000220000030000000001142000001400000000000000000000600000000000000000000000000000003300000000004200000000000000000
SPPN5Bacteria;Cyanobacteria;Gloeobacteria;Gloeobacterales;Gloeobacteraceae;Gloeobacter;multispecies_sppn5_2_nov_84.211%000000001662000000000000700000000000040000067000000007008300200102000000050538290236200000000000001911008640000000200000000000020001200000000000000000000000000000000008002900000000000000000005000015000000000000009000000000000000003600000000056200000005700000060000000000000000000000000001605300001900000000000000000000000000088000000010719010000000000004000000000000000000000000000000030000000000020000000000000001300200000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004000000000000000000000000000000000000006000
SPPN9Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Fusobacteriaceae;Fusobacterium;multispecies_sppn9_3_nov_97.845%000000000000000097101000005564900001100000000000090600013005642050000003003420000036000000022141100000036034000310018719000571800012012090013746000009716360000000000000300000600000176100060900000000000006000310000002118310000730000210000000525000000191800240000040090000009000001604312200014000710170003700160000405000806502401101600000781210909700000000000000002500003919170034016000000000000000000000000400000000000000000000000000000001170000000002450000000000000030000000000140000000000320640000000009420000001811900000000000000000000000000000000470000000000000000000000000000000000000070000000000000000000000000000000000700000007600000000000000000000000000000001207010000005160008100000000040000000000000000000
 
 
Download OTU Tables at Different Taxonomy Levels
PhylumCount*: Relative**: CLR***:
ClassCount*: Relative**: CLR***:
OrderCount*: Relative**: CLR***:
FamilyCount*: Relative**: CLR***:
GenusCount*: Relative**: CLR***:
SpeciesCount*: Relative**: CLR***:
* Read count
** Relative abundance (count/total sample count)
*** Centered log ratio transformed abundance
;
 
The species listed in the table has full taxonomy and a dynamically assigned species ID specific to this report. When some reads match with the reference sequences of more than one species equally (i.e., same percent identiy and alignmnet coverage), they can't be assigned to a particular species. Instead, they are assigned to multiple species with the species notaton "s__multispecies_spp2_2". In this notation, spp2 is the dynamic ID assigned to these reads that hit multiple sequences and the "_2" at the end of the notation means there are two species in the spp2.

You can look up which species are included in the multi-species assignment, in this table below:
 
 
 
 
Another type of notation is "s__multispecies_sppn2_2", in which the "n" in the sppn2 means it's a potential novel species because all the reads in this species have < 98% idenity to any of the reference sequences. They were grouped together based on de novo OTU clustering at 98% identity cutoff. And then a representative sequence was chosed to BLASTN search against the reference database to find the closest match (but will still be < 98%). This representative sequence also matched equally to more than one species, hence the "spp" was given in the label.
 
 

Taxonomy Bar Plots for All Samples

 
 

Taxonomy Bar Plots for Individual Comparison Groups

 
 
Comparison No.Comparison NameFamiliesGeneraSpecies
Comparison 1Saliva.V1.Brush_Only vs Saliva.V3.Brush_OnlyPDFSVGPDFSVGPDFSVG
Comparison 2Saliva.V1.Jolly_Rancher vs Saliva.V3.Jolly_RancherPDFSVGPDFSVGPDFSVG
Comparison 3Saliva.V1.Listerine vs Saliva.V3.ListerinePDFSVGPDFSVGPDFSVG
Comparison 4Saliva.V3.Brush_Only vs Saliva.V3.Jolly_RancherPDFSVGPDFSVGPDFSVG
Comparison 5Saliva.V3.Brush_Only vs Saliva.V3.ListerinePDFSVGPDFSVGPDFSVG
Comparison 6Saliva.V3.Jolly_Rancher vs Saliva.V3.ListerinePDFSVGPDFSVGPDFSVG
Comparison 7Plaque.V1.Brush_Only vs Plaque.V3.Brush_OnlyPDFSVGPDFSVGPDFSVG
Comparison 8Plaque.V1.Jolly_Rancher vs Plaque.V3.Jolly_RancherPDFSVGPDFSVGPDFSVG
Comparison 9Plaque.V1.Listerine vs Plaque.V3.ListerinePDFSVGPDFSVGPDFSVG
Comparison 10Plaque.V3.Brush_Only vs Plaque.V3.Jolly_RancherPDFSVGPDFSVGPDFSVG
Comparison 11Plaque.V3.Brush_Only vs Plaque.V3.ListerinePDFSVGPDFSVGPDFSVG
Comparison 12Plaque.V3.Jolly_Rancher vs Plaque.V3.ListerinePDFSVGPDFSVGPDFSVG
 
 

VIII. Analysis - Alpha Diversity

 

In ecology, alpha diversity (α-diversity) is the mean species diversity in sites or habitats at a local scale. The term was introduced by R. H. Whittaker[5][6] together with the terms beta diversity (β-diversity) and gamma diversity (γ-diversity). Whittaker's idea was that the total species diversity in a landscape (gamma diversity) is determined by two different things, the mean species diversity in sites or habitats at a more local scale (alpha diversity) and the differentiation among those habitats (beta diversity).

 

References:

  1. Whittaker, R. H. (1960) Vegetation of the Siskiyou Mountains, Oregon and California. Ecological Monographs, 30, 279–338. doi:10.2307/1943563
  2. Whittaker, R. H. (1972). Evolution and Measurement of Species Diversity. Taxon, 21, 213-251. doi:10.2307/1218190

 

Alpha Diversity Analysis by Rarefaction

Diversity measures are affected by the sampling depth. Rarefaction is a technique to assess species richness from the results of sampling. Rarefaction allows the calculation of species richness for a given number of individual samples, based on the construction of so-called rarefaction curves. This curve is a plot of the number of species as a function of the number of samples. Rarefaction curves generally grow rapidly at first, as the most common species are found, but the curves plateau as only the rarest species remain to be sampled [7].


References:

  1. Willis AD. Rarefaction, Alpha Diversity, and Statistics. Front Microbiol. 2019 Oct 23;10:2407. doi: 10.3389/fmicb.2019.02407. PMID: 31708888; PMCID: PMC6819366.

 
 
 

Boxplot of Alpha-diversity Indices

The two main factors taken into account when measuring diversity are richness and evenness. Richness is a measure of the number of different kinds of organisms present in a particular area. Evenness compares the similarity of the population size of each of the species present. There are many different ways to measure the richness and evenness. These measurements are called "estimators" or "indices". Below is a diversity of 3 commonly used indices showing the values for all the samples (dots) and in groups (boxes).

Printed on each graph is the statistical significance p values of the difference between the groups. The significance is calculated using either Kruskal-Wallis test or the Wilcoxon rank sum test, both are non-parametric methods (since microbiome read count data are considered non-normally distributed) for testing whether samples originate from the same distribution (i.e., no difference between groups). The Kruskal-Wallis test is used to compare three or more independent groups to determine if there are statistically significant differences between their medians. The Wilcoxon Rank Sum test, also known as the Mann-Whitney U test, is used to compare two independent groups to determine if there is a significant difference between their distributions.
The p-value is shown on the top of each graph. A p-value < 0.05 is considered statistically significant between/among the test groups.

 
Alpha Diversity Box Plots for All Groups
 
 
 
 
 
 
 
Alpha Diversity Box Plots for Individual Comparisons at Species level
 
Comparison 1Saliva.V1.Brush_Only vs Saliva.V3.Brush_OnlyView in PDFView in SVG
Comparison 2Saliva.V1.Jolly_Rancher vs Saliva.V3.Jolly_RancherView in PDFView in SVG
Comparison 3Saliva.V1.Listerine vs Saliva.V3.ListerineView in PDFView in SVG
Comparison 4Saliva.V3.Brush_Only vs Saliva.V3.Jolly_RancherView in PDFView in SVG
Comparison 5Saliva.V3.Brush_Only vs Saliva.V3.ListerineView in PDFView in SVG
Comparison 6Saliva.V3.Jolly_Rancher vs Saliva.V3.ListerineView in PDFView in SVG
Comparison 7Plaque.V1.Brush_Only vs Plaque.V3.Brush_OnlyView in PDFView in SVG
Comparison 8Plaque.V1.Jolly_Rancher vs Plaque.V3.Jolly_RancherView in PDFView in SVG
Comparison 9Plaque.V1.Listerine vs Plaque.V3.ListerineView in PDFView in SVG
Comparison 10Plaque.V3.Brush_Only vs Plaque.V3.Jolly_RancherView in PDFView in SVG
Comparison 11Plaque.V3.Brush_Only vs Plaque.V3.ListerineView in PDFView in SVG
Comparison 12Plaque.V3.Jolly_Rancher vs Plaque.V3.ListerineView in PDFView in SVG
 
The above comparisons are at the species-level. Comparisons of other taxonomy levels, from phylum to genus, are also available:
 
 
 
 

Group Significance Evaluation of Alpha-diversity Indices with QIIME2

The above comparisons and significance tests were done under the R environment. For compasison (also because this was included in the pipeline early on) we also use the Kruskal Wallis H test provided the "alpha-group-significance" fucntion in the QIIME 2 "diversity" package. As mentioned above, Kruskal Wallis test is the non-parametric alternative to the One Way ANOVA. Non-parametric means that the test doesn’t assume your data comes from a particular distribution. The H test is used when the assumptions for ANOVA aren’t met (assumption of normality). It is sometimes called the one-way ANOVA on ranks, as the ranks of the data values are used in the test rather than the actual data points. The H test determines whether the medians of two or more groups are different.

Below are the Kruskal Wallis H test results for each comparison based on three different alpha diversity measures: 1) Observed species (features), 2) Shannon index, and 3) Simpson index.

 
 
Comparison 1.Saliva.V1.Brush_Only vs Saliva.V3.Brush_OnlyObserved FeaturesShannon IndexSimpson Index
Comparison 2.Saliva.V1.Jolly_Rancher vs Saliva.V3.Jolly_RancherObserved FeaturesShannon IndexSimpson Index
Comparison 3.Saliva.V1.Listerine vs Saliva.V3.ListerineObserved FeaturesShannon IndexSimpson Index
Comparison 4.Saliva.V3.Brush_Only vs Saliva.V3.Jolly_RancherObserved FeaturesShannon IndexSimpson Index
Comparison 5.Saliva.V3.Brush_Only vs Saliva.V3.ListerineObserved FeaturesShannon IndexSimpson Index
Comparison 6.Saliva.V3.Jolly_Rancher vs Saliva.V3.ListerineObserved FeaturesShannon IndexSimpson Index
Comparison 7.Plaque.V1.Brush_Only vs Plaque.V3.Brush_OnlyObserved FeaturesShannon IndexSimpson Index
Comparison 8.Plaque.V1.Jolly_Rancher vs Plaque.V3.Jolly_RancherObserved FeaturesShannon IndexSimpson Index
Comparison 9.Plaque.V1.Listerine vs Plaque.V3.ListerineObserved FeaturesShannon IndexSimpson Index
Comparison 10.Plaque.V3.Brush_Only vs Plaque.V3.Jolly_RancherObserved FeaturesShannon IndexSimpson Index
Comparison 11.Plaque.V3.Brush_Only vs Plaque.V3.ListerineObserved FeaturesShannon IndexSimpson Index
Comparison 12.Plaque.V3.Jolly_Rancher vs Plaque.V3.ListerineObserved FeaturesShannon IndexSimpson Index
 
 

IX. Analysis - Beta Diversity

 

NMDS and PCoA Plots

Beta diversity compares the similarity (or dissimilarity) of microbial profiles between different groups of samples. There are many different similarity/dissimilarity metrics [8]. In general, they can be quantitative (using sequence abundance, e.g., Bray-Curtis or weighted UniFrac) or binary (considering only presence-absence of sequences, e.g., binary Jaccard or unweighted UniFrac). They can be even based on phylogeny (e.g., UniFrac metrics) or not (non-UniFrac metrics, such as Bray-Curtis, etc.).

For microbiome studies, species profiles of samples can be compared with the Bray-Curtis dissimilarity, which is based on the count data type. The pair-wise Bray-Curtis dissimilarity matrix of all samples can then be subject to either multi-dimensional scaling (MDS, also known as PCoA) or non-metric MDS (NMDS).

MDS/PCoA is a scaling or ordination method that starts with a matrix of similarities or dissimilarities between a set of samples and aims to produce a low-dimensional graphical plot of the data in such a way that distances between points in the plot are close to original dissimilarities.

NMDS is similar to MDS, however it does not use the dissimilarities data, instead it converts them into the ranks and use these ranks in the calculation.

In our beta diversity analysis, Bray-Curtis dissimilarity matrix was first calculated and then plotted by the PCoA and NMDS separately. Below are beta diveristy results for all groups together:

References:

  1. Plantinga, AM, Wu, MC (2021). Beta Diversity and Distance-Based Analysis of Microbiome Data. In: Datta, S., Guha, S. (eds) Statistical Analysis of Microbiome Data. Frontiers in Probability and the Statistical Sciences. Springer, Cham. https://doi.org/10.1007/978-3-030-73351-3_5

 
 
NMDS and PCoA Plots for All Groups
 
 
 
 
 

The above PCoA and NMDS plots are based on count data. The count data can also be transformed into centered log ratio (CLR) for each species. The CLR data is no longer count data and cannot be used in Bray-Curtis dissimilarity calculation. Instead CLR can be compared with Euclidean distances. When CLR data are compared by Euclidean distance, the distance is also called Aitchison distance.

Below are the NMDS and PCoA plots of the Aitchison distances of the samples:

 
 
 
 
 
 
 
NMDS and PCoA Plots for Individual Comparisons at Species level
 
 
Comparison No.Comparison NameNMDAPCoA
Bray-CurtisCLR EuclideanBray-CurtisCLR Euclidean
Comparison 1Saliva.V1.Brush_Only vs Saliva.V3.Brush_OnlyPDFSVGPDFSVGPDFSVGPDFSVG
Comparison 2Saliva.V1.Jolly_Rancher vs Saliva.V3.Jolly_RancherPDFSVGPDFSVGPDFSVGPDFSVG
Comparison 3Saliva.V1.Listerine vs Saliva.V3.ListerinePDFSVGPDFSVGPDFSVGPDFSVG
Comparison 4Saliva.V3.Brush_Only vs Saliva.V3.Jolly_RancherPDFSVGPDFSVGPDFSVGPDFSVG
Comparison 5Saliva.V3.Brush_Only vs Saliva.V3.ListerinePDFSVGPDFSVGPDFSVGPDFSVG
Comparison 6Saliva.V3.Jolly_Rancher vs Saliva.V3.ListerinePDFSVGPDFSVGPDFSVGPDFSVG
Comparison 7Plaque.V1.Brush_Only vs Plaque.V3.Brush_OnlyPDFSVGPDFSVGPDFSVGPDFSVG
Comparison 8Plaque.V1.Jolly_Rancher vs Plaque.V3.Jolly_RancherPDFSVGPDFSVGPDFSVGPDFSVG
Comparison 9Plaque.V1.Listerine vs Plaque.V3.ListerinePDFSVGPDFSVGPDFSVGPDFSVG
Comparison 10Plaque.V3.Brush_Only vs Plaque.V3.Jolly_RancherPDFSVGPDFSVGPDFSVGPDFSVG
Comparison 11Plaque.V3.Brush_Only vs Plaque.V3.ListerinePDFSVGPDFSVGPDFSVGPDFSVG
Comparison 12Plaque.V3.Jolly_Rancher vs Plaque.V3.ListerinePDFSVGPDFSVGPDFSVGPDFSVG
 
 
 
 
 
 

Interactive 3D PCoA Plots - Bray-Curtis Dissimilarity

 
 
 

Interactive 3D PCoA Plots - Euclidean Distance

 
 
 

Interactive 3D PCoA Plots - Correlation Coefficients

 
 
 

Group Significance of Beta-diversity Indices

To test whether the between-group dissimilarities are significantly greater than the within-group dissimilarities, the "beta-group-significance" function provided in the QIIME 2 "diversity" package was used with PERMANOVA (permutational multivariate analysis of variance) as the group significant testing method.

Three beta diversity matrics were used: 1) Bray–Curtis dissimilarity 2) Correlation coefficient matrix , and 3) Aitchison distance (Euclidean distance between clr-transformed compositions).

 
 
Comparison 1.Saliva.V1.Brush_Only vs Saliva.V3.Brush_OnlyBray–CurtisCorrelationAitchison
Comparison 2.Saliva.V1.Jolly_Rancher vs Saliva.V3.Jolly_RancherBray–CurtisCorrelationAitchison
Comparison 3.Saliva.V1.Listerine vs Saliva.V3.ListerineBray–CurtisCorrelationAitchison
Comparison 4.Saliva.V3.Brush_Only vs Saliva.V3.Jolly_RancherBray–CurtisCorrelationAitchison
Comparison 5.Saliva.V3.Brush_Only vs Saliva.V3.ListerineBray–CurtisCorrelationAitchison
Comparison 6.Saliva.V3.Jolly_Rancher vs Saliva.V3.ListerineBray–CurtisCorrelationAitchison
Comparison 7.Plaque.V1.Brush_Only vs Plaque.V3.Brush_OnlyBray–CurtisCorrelationAitchison
Comparison 8.Plaque.V1.Jolly_Rancher vs Plaque.V3.Jolly_RancherBray–CurtisCorrelationAitchison
Comparison 9.Plaque.V1.Listerine vs Plaque.V3.ListerineBray–CurtisCorrelationAitchison
Comparison 10.Plaque.V3.Brush_Only vs Plaque.V3.Jolly_RancherBray–CurtisCorrelationAitchison
Comparison 11.Plaque.V3.Brush_Only vs Plaque.V3.ListerineBray–CurtisCorrelationAitchison
Comparison 12.Plaque.V3.Jolly_Rancher vs Plaque.V3.ListerineBray–CurtisCorrelationAitchison
 
 
 

X. Analysis - Differential Abundance

16S rRNA next generation sequencing (NGS) generates a fixed number of reads that reflect the proportion of different species in a sample, i.e., the relative abundance of species, instead of the absolute abundance. In Mathematics, measurements involving probabilities, proportions, percentages, and ppm can all be thought of as compositional data. This makes the microbiome read count data “compositional” (Gloor et al, 2017). In general, compositional data represent parts of a whole which only carry relative information [9].

The problem of microbiome data being compositional arises when comparing two groups of samples for identifying “differentially abundant” species. A species with the same absolute abundance between two conditions, its relative abundances in the two conditions (e.g., percent abundance) can become different if the relative abundance of other species change greatly. This problem can lead to incorrect conclusion in terms of differential abundance for microbial species in the samples.

When studying differential abundance (DA), the current better approach is to transform the read count data into log ratio data. The ratios are calculated between read counts of all species in a sample to a “reference” count (e.g., mean read count of the sample). The log ratio data allow the detection of DA species without being affected by percentage bias mentioned above

In this report, a compositional DA analysis tool “ANCOM” (analysis of composition of microbiomes) was used [10]. ANCOM transforms the count data into log-ratios and thus is more suitable for comparing the composition of microbiomes in two or more populations. "ANCOM" generates a table of features with W-statistics and whether the null hypothesis is rejected. The “W” is the W-statistic, or number of features that a single feature is tested to be significantly different against. Hence the higher the "W" the more statistical sifgnificant that a feature/species is differentially abundant.

References:

  1. Gloor GB, Macklaim JM, Pawlowsky-Glahn V, Egozcue JJ. Microbiome Datasets Are Compositional: And This Is Not Optional. Front Microbiol. 2017 Nov 15;8:2224. doi: 10.3389/fmicb.2017.02224. PMID: 29187837; PMCID: PMC5695134.
  2. Mandal S, Van Treuren W, White RA, Eggesbø M, Knight R, Peddada SD. Analysis of composition of microbiomes: a novel method for studying microbial composition. Microb Ecol Health Dis. 2015 May 29;26:27663. doi: 10.3402/mehd.v26.27663. PMID: 26028277; PMCID: PMC4450248.
 
 

ANCOM Differential Abundance Analysis

 
ANCOM Results for Individual Comparisons
Comparison No.Comparison Name
Comparison 1.Saliva.V1.Brush_Only vs Saliva.V3.Brush_Only
Comparison 2.Saliva.V1.Jolly_Rancher vs Saliva.V3.Jolly_Rancher
Comparison 3.Saliva.V1.Listerine vs Saliva.V3.Listerine
Comparison 4.Saliva.V3.Brush_Only vs Saliva.V3.Jolly_Rancher
Comparison 5.Saliva.V3.Brush_Only vs Saliva.V3.Listerine
Comparison 6.Saliva.V3.Jolly_Rancher vs Saliva.V3.Listerine
Comparison 7.Plaque.V1.Brush_Only vs Plaque.V3.Brush_Only
Comparison 8.Plaque.V1.Jolly_Rancher vs Plaque.V3.Jolly_Rancher
Comparison 9.Plaque.V1.Listerine vs Plaque.V3.Listerine
Comparison 10.Plaque.V3.Brush_Only vs Plaque.V3.Jolly_Rancher
Comparison 11.Plaque.V3.Brush_Only vs Plaque.V3.Listerine
Comparison 12.Plaque.V3.Jolly_Rancher vs Plaque.V3.Listerine
 
 

ANCOM-BC2 Differential Abundance Analysis

 

Starting with version V1.2, we include the results of ANCOM-BC (Analysis of Compositions of Microbiomes with Bias Correction) (Lin and Peddada 2020) [11]. ANCOM-BC is an updated version of "ANCOM" that:
(a) provides statistically valid test with appropriate p-values,
(b) provides confidence intervals for differential abundance of each taxon,
(c) controls the False Discovery Rate (FDR),
(d) maintains adequate power, and
(e) is computationally simple to implement.

The bias correction (BC) addresses a challenging problem of the bias introduced by differences in the sampling fractions across samples. This bias has been a major hurdle in performing DA analysis of microbiome data. ANCOM-BC estimates the unknown sampling fractions and corrects the bias induced by their differences among samples. The absolute abundance data are modeled using a linear regression framework.

Starting with version V1.43, ANCOM-BC2 is used instead of ANCOM-BC, So that multiple pairwise directional test can be performed (if there are more than two gorups in a comparison). When performing pairwise directional test, the mixed directional false discover rate (mdFDR) is taken into account. The mdFDR is the combination of false discovery rate due to multiple testing, multiple pairwise comparisons, and directional tests within each pairwise comparison. The mdFDR is adopted from (Guo, Sarkar, and Peddada 2010 [12]; Grandhi, Guo, and Peddada 2016 [13]). For more detail explanation and additional features of ANCOM-BC2 please see author's documentation.

References:

  1. Lin H, Peddada SD. Analysis of compositions of microbiomes with bias correction. Nat Commun. 2020 Jul 14;11(1):3514. doi: 10.1038/s41467-020-17041-7. PMID: 32665548; PMCID: PMC7360769.
  2. Guo W, Sarkar SK, Peddada SD. Controlling false discoveries in multidimensional directional decisions, with applications to gene expression data on ordered categories. Biometrics. 2010 Jun;66(2):485-92. doi: 10.1111/j.1541-0420.2009.01292.x. Epub 2009 Jul 23. PMID: 19645703; PMCID: PMC2895927.
  3. Grandhi A, Guo W, Peddada SD. A multiple testing procedure for multi-dimensional pairwise comparisons with application to gene expression studies. BMC Bioinformatics. 2016 Feb 25;17:104. doi: 10.1186/s12859-016-0937-5. PMID: 26917217; PMCID: PMC4768411.
 
 
ANCOM-BC Results for Individual Comparisons
 
Comparison No.Comparison Name
Comparison 1.Saliva.V1.Brush_Only vs Saliva.V3.Brush_Only
Comparison 2.Saliva.V1.Jolly_Rancher vs Saliva.V3.Jolly_Rancher
Comparison 3.Saliva.V1.Listerine vs Saliva.V3.Listerine
Comparison 4.Saliva.V3.Brush_Only vs Saliva.V3.Jolly_Rancher
Comparison 5.Saliva.V3.Brush_Only vs Saliva.V3.Listerine
Comparison 6.Saliva.V3.Jolly_Rancher vs Saliva.V3.Listerine
Comparison 7.Plaque.V1.Brush_Only vs Plaque.V3.Brush_Only
Comparison 8.Plaque.V1.Jolly_Rancher vs Plaque.V3.Jolly_Rancher
Comparison 9.Plaque.V1.Listerine vs Plaque.V3.Listerine
Comparison 10.Plaque.V3.Brush_Only vs Plaque.V3.Jolly_Rancher
Comparison 11.Plaque.V3.Brush_Only vs Plaque.V3.Listerine
Comparison 12.Plaque.V3.Jolly_Rancher vs Plaque.V3.Listerine
 
 
 
 
 

LEfSe - Linear Discriminant Analysis Effect Size

LEfSe (Linear Discriminant Analysis Effect Size) is an alternative method to find "organisms, genes, or pathways that consistently explain the differences between two or more microbial communities" (Segata et al., 2011) [14]. Specifically, LEfSe uses rank-based Kruskal-Wallis (KW) sum-rank test to detect features with significant differential (relative) abundance with respect to the class of interest. Since it is rank-based, instead of proportional based, the differential species identified among the comparison groups is less biased (than percent abundance based).

Reference:

  1. Segata N, Izard J, Waldron L, Gevers D, Miropolsky L, Garrett WS, Huttenhower C. Metagenomic biomarker discovery and explanation. Genome Biol. 2011 Jun 24;12(6):R60. doi: 10.1186/gb-2011-12-6-r60. PMID: 21702898; PMCID: PMC3218848.
 
Saliva.V1.Brush_Only vs Saliva.V3.Brush_Only
 
 
 
 
 
 
 
LEfSe Results for All Comparisons
 
Comparison No.Comparison Name
Comparison 1.Saliva.V1.Brush_Only vs Saliva.V3.Brush_Only
Comparison 2.Saliva.V1.Jolly_Rancher vs Saliva.V3.Jolly_Rancher
Comparison 3.Saliva.V1.Listerine vs Saliva.V3.Listerine
Comparison 4.Saliva.V3.Brush_Only vs Saliva.V3.Jolly_Rancher
Comparison 5.Saliva.V3.Brush_Only vs Saliva.V3.Listerine
Comparison 6.Saliva.V3.Jolly_Rancher vs Saliva.V3.Listerine
Comparison 7.Plaque.V1.Brush_Only vs Plaque.V3.Brush_Only
Comparison 8.Plaque.V1.Jolly_Rancher vs Plaque.V3.Jolly_Rancher
Comparison 9.Plaque.V1.Listerine vs Plaque.V3.Listerine
Comparison 10.Plaque.V3.Brush_Only vs Plaque.V3.Jolly_Rancher
Comparison 11.Plaque.V3.Brush_Only vs Plaque.V3.Listerine
Comparison 12.Plaque.V3.Jolly_Rancher vs Plaque.V3.Listerine
 
 

XI. Analysis - Heatmap Profile

 

Species vs Sample Abundance Heatmap for All Samples

 
 
 

Heatmaps for Individual Comparisons

 
A) Two-way clustering - clustered on both columns (Samples) and rows (organism)
Comparison No.Comparison NameFamily LevelGenus LevelSpecies Level
Comparison 1Saliva.V1.Brush_Only vs Saliva.V3.Brush_OnlyPDFSVGPDFSVGPDFSVG
Comparison 2Saliva.V1.Jolly_Rancher vs Saliva.V3.Jolly_RancherPDFSVGPDFSVGPDFSVG
Comparison 3Saliva.V1.Listerine vs Saliva.V3.ListerinePDFSVGPDFSVGPDFSVG
Comparison 4Saliva.V3.Brush_Only vs Saliva.V3.Jolly_RancherPDFSVGPDFSVGPDFSVG
Comparison 5Saliva.V3.Brush_Only vs Saliva.V3.ListerinePDFSVGPDFSVGPDFSVG
Comparison 6Saliva.V3.Jolly_Rancher vs Saliva.V3.ListerinePDFSVGPDFSVGPDFSVG
Comparison 7Plaque.V1.Brush_Only vs Plaque.V3.Brush_OnlyPDFSVGPDFSVGPDFSVG
Comparison 8Plaque.V1.Jolly_Rancher vs Plaque.V3.Jolly_RancherPDFSVGPDFSVGPDFSVG
Comparison 9Plaque.V1.Listerine vs Plaque.V3.ListerinePDFSVGPDFSVGPDFSVG
Comparison 10Plaque.V3.Brush_Only vs Plaque.V3.Jolly_RancherPDFSVGPDFSVGPDFSVG
Comparison 11Plaque.V3.Brush_Only vs Plaque.V3.ListerinePDFSVGPDFSVGPDFSVG
Comparison 12Plaque.V3.Jolly_Rancher vs Plaque.V3.ListerinePDFSVGPDFSVGPDFSVG
 
 
B) One-way clustering - clustered on rows (organism) only
Comparison No.Comparison NameFamily LevelGenus LevelSpecies Level
Comparison 1Saliva.V1.Brush_Only vs Saliva.V3.Brush_OnlyPDFSVGPDFSVGPDFSVG
Comparison 2Saliva.V1.Jolly_Rancher vs Saliva.V3.Jolly_RancherPDFSVGPDFSVGPDFSVG
Comparison 3Saliva.V1.Listerine vs Saliva.V3.ListerinePDFSVGPDFSVGPDFSVG
Comparison 4Saliva.V3.Brush_Only vs Saliva.V3.Jolly_RancherPDFSVGPDFSVGPDFSVG
Comparison 5Saliva.V3.Brush_Only vs Saliva.V3.ListerinePDFSVGPDFSVGPDFSVG
Comparison 6Saliva.V3.Jolly_Rancher vs Saliva.V3.ListerinePDFSVGPDFSVGPDFSVG
Comparison 7Plaque.V1.Brush_Only vs Plaque.V3.Brush_OnlyPDFSVGPDFSVGPDFSVG
Comparison 8Plaque.V1.Jolly_Rancher vs Plaque.V3.Jolly_RancherPDFSVGPDFSVGPDFSVG
Comparison 9Plaque.V1.Listerine vs Plaque.V3.ListerinePDFSVGPDFSVGPDFSVG
Comparison 10Plaque.V3.Brush_Only vs Plaque.V3.Jolly_RancherPDFSVGPDFSVGPDFSVG
Comparison 11Plaque.V3.Brush_Only vs Plaque.V3.ListerinePDFSVGPDFSVGPDFSVG
Comparison 12Plaque.V3.Jolly_Rancher vs Plaque.V3.ListerinePDFSVGPDFSVGPDFSVG
 
 
C) No clustering
Comparison No.Comparison NameFamily LevelGenus LevelSpecies Level
Comparison 1Saliva.V1.Brush_Only vs Saliva.V3.Brush_OnlyPDFSVGPDFSVGPDFSVG
Comparison 2Saliva.V1.Jolly_Rancher vs Saliva.V3.Jolly_RancherPDFSVGPDFSVGPDFSVG
Comparison 3Saliva.V1.Listerine vs Saliva.V3.ListerinePDFSVGPDFSVGPDFSVG
Comparison 4Saliva.V3.Brush_Only vs Saliva.V3.Jolly_RancherPDFSVGPDFSVGPDFSVG
Comparison 5Saliva.V3.Brush_Only vs Saliva.V3.ListerinePDFSVGPDFSVGPDFSVG
Comparison 6Saliva.V3.Jolly_Rancher vs Saliva.V3.ListerinePDFSVGPDFSVGPDFSVG
Comparison 7Plaque.V1.Brush_Only vs Plaque.V3.Brush_OnlyPDFSVGPDFSVGPDFSVG
Comparison 8Plaque.V1.Jolly_Rancher vs Plaque.V3.Jolly_RancherPDFSVGPDFSVGPDFSVG
Comparison 9Plaque.V1.Listerine vs Plaque.V3.ListerinePDFSVGPDFSVGPDFSVG
Comparison 10Plaque.V3.Brush_Only vs Plaque.V3.Jolly_RancherPDFSVGPDFSVGPDFSVG
Comparison 11Plaque.V3.Brush_Only vs Plaque.V3.ListerinePDFSVGPDFSVGPDFSVG
Comparison 12Plaque.V3.Jolly_Rancher vs Plaque.V3.ListerinePDFSVGPDFSVGPDFSVG
 
 

XII. Analysis - Network Association

To analyze the co-occurrence or co-exclusion between microbial species among different samples, network correlation analysis tools are usually used for this purpose. However, microbiome count data are compositional. If count data are normalized to the total number of counts in the sample, the data become not independent and traditional statistical metrics (e.g., correlation) for the detection of specie-species relationships can lead to spurious results. In addition, sequencing-based studies typically measure hundreds of OTUs (species) on few samples; thus, inference of OTU-OTU association networks is severely under-powered. Here we use SPIEC-EASI (SParse InversE Covariance Estimation for Ecological Association Inference), a statistical method for the inference of microbial ecological networks from amplicon sequencing datasets that addresses both of these issues (Kurtz et al., 2015) [15]. SPIEC-EASI combines data transformations developed for compositional data analysis with a graphical model inference framework that assumes the underlying ecological association network is sparse. SPIEC-EASI provides two algorithms for network inferencing – 1) Meinshausen-Bühlmann's neighborhood selection (MB method) and inverse covariance selection (GLASSO method, i.e., graphical least absolute shrinkage and selection operator). This is fundamentally distinct from SparCC, which essentially estimate pairwise correlations. In addition to these two methods, we provide the results of a third method - SparCC (Sparse Correlations for Compositional Data)(Friedman & Alm 2012)[16], which is also a method for inferring correlations from compositional data. SparCC estimates the linear Pearson correlations between the log-transformed components.

References:

  1. Kurtz ZD, Müller CL, Miraldi ER, Littman DR, Blaser MJ, Bonneau RA. Sparse and compositionally robust inference of microbial ecological networks. PLoS Comput Biol. 2015 May 7;11(5):e1004226. doi: 10.1371/journal.pcbi.1004226. PMID: 25950956; PMCID: PMC4423992.
  2. Friedman J, Alm EJ. Inferring correlation networks from genomic survey data. PLoS Comput Biol. 2012;8(9):e1002687. doi: 10.1371/journal.pcbi.1002687. Epub 2012 Sep 20. PMID: 23028285; PMCID: PMC3447976.
 

SPIEC-EASI Network Inference by Neighborhood Selection (MB Method)

 
 

 

Association Network Inference by SparCC

 
 

 
 

XIII. Disclaimer

The results of this analysis are for research purpose only. They are not intended to diagnose, treat, cure, or prevent any disease. Forsyth and FOMC are not responsible for use of information provided in this report outside the research area.

 
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